{"id":"https://openalex.org/W2033980362","doi":"https://doi.org/10.1109/tsmcc.2012.2217326","title":"Using Multidimensional Bayesian Network Classifiers to Assist the Treatment of Multiple Sclerosis","display_name":"Using Multidimensional Bayesian Network Classifiers to Assist the Treatment of Multiple Sclerosis","publication_year":2012,"publication_date":"2012-11-01","ids":{"openalex":"https://openalex.org/W2033980362","doi":"https://doi.org/10.1109/tsmcc.2012.2217326","mag":"2033980362"},"language":"en","primary_location":{"id":"doi:10.1109/tsmcc.2012.2217326","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tsmcc.2012.2217326","pdf_url":null,"source":{"id":"https://openalex.org/S4210227557","display_name":"IEEE Transactions on Systems Man and Cybernetics Part C (Applications and Reviews)","issn_l":"1094-6977","issn":["1094-6977","1558-2442"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Systems, Man, and Cybernetics, Part C (Applications and Reviews)","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104171289","display_name":"Juan Diego Rodr\u00edguez","orcid":null},"institutions":[{"id":"https://openalex.org/I169108374","display_name":"University of the Basque Country","ror":"https://ror.org/000xsnr85","country_code":"ES","type":"education","lineage":["https://openalex.org/I169108374"]},{"id":"https://openalex.org/I4210105785","display_name":"Intelligent Systems Research (United States)","ror":"https://ror.org/01reevc91","country_code":"US","type":"company","lineage":["https://openalex.org/I4210105785"]}],"countries":["ES","US"],"is_corresponding":false,"raw_author_name":"Juan Diego Rodriguez","raw_affiliation_strings":["Intelligent Systems Group, Department of Computer Science and Artificial Intelligence, University of the Basque Country, San Sebastian, Spain","Dept. of Comput. Sci. & Artificial Intell., Univ. of the Basque Country, San Sebastian, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Intelligent Systems Group, Department of Computer Science and Artificial Intelligence, University of the Basque Country, San Sebastian, Spain","institution_ids":["https://openalex.org/I4210105785"]},{"raw_affiliation_string":"Dept. of Comput. Sci. & Artificial Intell., Univ. of the Basque Country, San Sebastian, Spain","institution_ids":["https://openalex.org/I169108374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053399459","display_name":"Aritz P\u00e9rez","orcid":"https://orcid.org/0000-0002-8128-1099"},"institutions":[{"id":"https://openalex.org/I169108374","display_name":"University of the Basque Country","ror":"https://ror.org/000xsnr85","country_code":"ES","type":"education","lineage":["https://openalex.org/I169108374"]},{"id":"https://openalex.org/I4210105785","display_name":"Intelligent Systems Research (United States)","ror":"https://ror.org/01reevc91","country_code":"US","type":"company","lineage":["https://openalex.org/I4210105785"]}],"countries":["ES","US"],"is_corresponding":false,"raw_author_name":"Aritz Perez","raw_affiliation_strings":["Intelligent Systems Group, Department of Computer Science and Artificial Intelligence, University of the Basque Country, San Sebastian, Spain","Dept. of Comput. Sci. & Artificial Intell., Univ. of the Basque Country, San Sebastian, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Intelligent Systems Group, Department of Computer Science and Artificial Intelligence, University of the Basque Country, San Sebastian, Spain","institution_ids":["https://openalex.org/I4210105785"]},{"raw_affiliation_string":"Dept. of Comput. Sci. & Artificial Intell., Univ. of the Basque Country, San Sebastian, Spain","institution_ids":["https://openalex.org/I169108374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103552921","display_name":"David Arteta","orcid":null},"institutions":[{"id":"https://openalex.org/I4210131846","display_name":"Artificial Intelligence Research Institute","ror":"https://ror.org/03c0ach84","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I4210131846"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"David Arteta","raw_affiliation_strings":["Intelligent Systems Group, Department of Computer Science and Artificial Intelligence, Progenika Biopharma S.A., Derio, Spain","Progenika Biopharma S.A., Derio, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Intelligent Systems Group, Department of Computer Science and Artificial Intelligence, Progenika Biopharma S.A., Derio, Spain","institution_ids":["https://openalex.org/I4210131846"]},{"raw_affiliation_string":"Progenika Biopharma S.A., Derio, Spain","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103469181","display_name":"Diego Tejedor","orcid":null},"institutions":[{"id":"https://openalex.org/I4210131846","display_name":"Artificial Intelligence Research Institute","ror":"https://ror.org/03c0ach84","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I4210131846"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Diego Tejedor","raw_affiliation_strings":["Intelligent Systems Group, Department of Computer Science and Artificial Intelligence, Progenika Biopharma S.A., Derio, Spain","Progenika Biopharma S.A., Derio, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Intelligent Systems Group, Department of Computer Science and Artificial Intelligence, Progenika Biopharma S.A., Derio, Spain","institution_ids":["https://openalex.org/I4210131846"]},{"raw_affiliation_string":"Progenika Biopharma S.A., Derio, Spain","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050500830","display_name":"Jos\u00e9 A. Lozano","orcid":"https://orcid.org/0000-0002-4683-8111"},"institutions":[{"id":"https://openalex.org/I169108374","display_name":"University of the Basque Country","ror":"https://ror.org/000xsnr85","country_code":"ES","type":"education","lineage":["https://openalex.org/I169108374"]},{"id":"https://openalex.org/I4210105785","display_name":"Intelligent Systems Research (United States)","ror":"https://ror.org/01reevc91","country_code":"US","type":"company","lineage":["https://openalex.org/I4210105785"]}],"countries":["ES","US"],"is_corresponding":false,"raw_author_name":"Jose A. Lozano","raw_affiliation_strings":["Intelligent Systems Group, Department of Computer Science and Artificial Intelligence, University of the Basque Country, San Sebastian, Spain","Dept. of Comput. Sci. & Artificial Intell., Univ. of the Basque Country, San Sebastian, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Intelligent Systems Group, Department of Computer Science and Artificial Intelligence, University of the Basque Country, San Sebastian, Spain","institution_ids":["https://openalex.org/I4210105785"]},{"raw_affiliation_string":"Dept. of Comput. Sci. & Artificial Intell., Univ. of the Basque Country, San Sebastian, Spain","institution_ids":["https://openalex.org/I169108374"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0594,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.75309818,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"42","issue":"6","first_page":"1705","last_page":"1715"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9927999973297119,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9927999973297119,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9836999773979187,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.954800009727478,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interpretability","display_name":"Interpretability","score":0.8951832056045532},{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"Multiple sclerosis","score":0.7030652761459351},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.6560873985290527},{"id":"https://openalex.org/keywords/bayesian-network","display_name":"Bayesian network","score":0.5968831777572632},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5942744612693787},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5701833963394165},{"id":"https://openalex.org/keywords/bayesian-probability","display_name":"Bayesian probability","score":0.525272011756897},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4964664578437805},{"id":"https://openalex.org/keywords/exploit","display_name":"Exploit","score":0.4962065815925598},{"id":"https://openalex.org/keywords/class","display_name":"Class (philosophy)","score":0.4801428020000458},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4598764479160309},{"id":"https://openalex.org/keywords/bayes-theorem","display_name":"Bayes' theorem","score":0.4369519054889679},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.42413222789764404},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.07934585213661194}],"concepts":[{"id":"https://openalex.org/C2781067378","wikidata":"https://www.wikidata.org/wiki/Q17027399","display_name":"Interpretability","level":2,"score":0.8951832056045532},{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.7030652761459351},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6560873985290527},{"id":"https://openalex.org/C33724603","wikidata":"https://www.wikidata.org/wiki/Q812540","display_name":"Bayesian network","level":2,"score":0.5968831777572632},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5942744612693787},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5701833963394165},{"id":"https://openalex.org/C107673813","wikidata":"https://www.wikidata.org/wiki/Q812534","display_name":"Bayesian probability","level":2,"score":0.525272011756897},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4964664578437805},{"id":"https://openalex.org/C165696696","wikidata":"https://www.wikidata.org/wiki/Q11287","display_name":"Exploit","level":2,"score":0.4962065815925598},{"id":"https://openalex.org/C2777212361","wikidata":"https://www.wikidata.org/wiki/Q5127848","display_name":"Class (philosophy)","level":2,"score":0.4801428020000458},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4598764479160309},{"id":"https://openalex.org/C207201462","wikidata":"https://www.wikidata.org/wiki/Q182505","display_name":"Bayes' theorem","level":3,"score":0.4369519054889679},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.42413222789764404},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.07934585213661194},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/tsmcc.2012.2217326","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tsmcc.2012.2217326","pdf_url":null,"source":{"id":"https://openalex.org/S4210227557","display_name":"IEEE Transactions on Systems Man and Cybernetics Part C (Applications and Reviews)","issn_l":"1094-6977","issn":["1094-6977","1558-2442"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Systems, Man, and Cybernetics, Part C (Applications and Reviews)","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.550000011920929,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W42649658","https://openalex.org/W193321262","https://openalex.org/W228173739","https://openalex.org/W229986433","https://openalex.org/W1495061682","https://openalex.org/W1502772707","https://openalex.org/W1505979743","https://openalex.org/W1515344597","https://openalex.org/W1528620860","https://openalex.org/W1530427892","https://openalex.org/W1538041071","https://openalex.org/W1550206324","https://openalex.org/W1560107318","https://openalex.org/W1562963886","https://openalex.org/W1563088657","https://openalex.org/W1593793857","https://openalex.org/W1625504505","https://openalex.org/W1678889691","https://openalex.org/W1680392829","https://openalex.org/W1817561967","https://openalex.org/W1853953842","https://openalex.org/W1970424517","https://openalex.org/W1984810231","https://openalex.org/W1994435442","https://openalex.org/W1999954155","https://openalex.org/W2008499862","https://openalex.org/W2013014665","https://openalex.org/W2045031658","https://openalex.org/W2049487246","https://openalex.org/W2065069176","https://openalex.org/W2098740506","https://openalex.org/W2099276641","https://openalex.org/W2111315936","https://openalex.org/W2112081648","https://openalex.org/W2112165124","https://openalex.org/W2112299196","https://openalex.org/W2122672280","https://openalex.org/W2123504579","https://openalex.org/W2139212933","https://openalex.org/W2139906483","https://openalex.org/W2143381319","https://openalex.org/W2146241755","https://openalex.org/W2147169507","https://openalex.org/W2148018895","https://openalex.org/W2150046657","https://openalex.org/W2156308848","https://openalex.org/W2156909104","https://openalex.org/W2158143121","https://openalex.org/W2171640468","https://openalex.org/W2228013739","https://openalex.org/W2401866995","https://openalex.org/W2611370172","https://openalex.org/W4241890711","https://openalex.org/W4244238212","https://openalex.org/W4285719527","https://openalex.org/W4292864963","https://openalex.org/W6632865047","https://openalex.org/W6636859864","https://openalex.org/W6637386731","https://openalex.org/W6639104094","https://openalex.org/W6682062829","https://openalex.org/W7057985793"],"related_works":["https://openalex.org/W2905433371","https://openalex.org/W2888392564","https://openalex.org/W4310278675","https://openalex.org/W4388422664","https://openalex.org/W4390569940","https://openalex.org/W4361193272","https://openalex.org/W2963326959","https://openalex.org/W4388685194","https://openalex.org/W4312407344","https://openalex.org/W2894289927"],"abstract_inverted_index":{"Multiple":[0],"sclerosis":[1,33],"is":[2,27,55,59,66,96,108,122,186],"an":[3],"autoimmune":[4],"disorder":[5],"of":[6,17,42,45,81,178,183,190,201,208,224],"the":[7,13,40,43,46,49,52,64,79,82,100,109,155,161,168,176,184,199,209,221,225,230],"central":[8],"nervous":[9],"system":[10],"and":[11,30,57,136,153,227],"potentially":[12],"most":[14,231],"common":[15],"cause":[16],"neurological":[18],"disability":[19],"in":[20,212],"young":[21],"adults.":[22],"The":[23,181,206],"clinical":[24],"disease":[25,53,101,134,226],"course":[26],"highly":[28,88],"variable":[29],"different":[31,73],"multiple":[32],"subtypes":[34],"can":[35,151,164,215],"be":[36,165],"defined":[37],"depending":[38,77],"on":[39,78],"progression":[41,80,223],"severity":[44,65,115,141],"disease.":[47],"In":[48],"early":[50,84],"stages,":[51],"subtype":[54,135],"unknown,":[56],"there":[58,71],"no":[60],"information":[61,105],"about":[62],"how":[63],"going":[67],"to":[68,98,106,112,128,138,175,197,219,228],"evolve.":[69],"As":[70],"are":[72],"treatment":[74],"options":[75],"available":[76],"disease,":[83],"identification":[85],"has":[86],"become":[87],"relevant.":[89],"Thus,":[90],"given":[91],"a":[92,114,191,217],"new":[93],"patient,":[94],"it":[95],"important":[97],"diagnose":[99],"subtype.":[102],"Another":[103],"relevant":[104],"predict":[107,129],"expected":[110,222],"time":[111,137],"reach":[113,139],"level":[116],"indicating":[117],"that":[118,125],"assistance":[119],"for":[120],"walking":[121],"required.":[123],"Given":[124],"we":[126,143],"have":[127],"two":[130],"correlated":[131],"class":[132,203],"variables:":[133],"certain":[140],"level,":[142],"use":[144],"multidimensional":[145],"Bayesian":[146,179],"network":[147],"classifiers":[148,185],"because":[149],"they":[150],"model":[152],"exploit":[154],"relations":[156],"among":[157],"both":[158,202],"variables.":[159],"Besides,":[160],"obtained":[162],"models":[163],"validated":[166],"by":[167,188],"physicians":[169],"using":[170],"their":[171],"expert":[172],"knowledge":[173],"due":[174],"interpretability":[177],"networks.":[180],"learning":[182],"made":[187],"means":[189],"novel":[192],"multiobjective":[193],"approach":[194],"which":[195],"tries":[196],"maximize":[198],"accuracy":[200],"variables":[204],"simultaneously.":[205],"application":[207],"methodology":[210],"proposed":[211],"this":[213],"paper":[214],"help":[216],"physician":[218],"identify":[220],"plan":[229],"suitable":[232],"treatment.":[233]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
