{"id":"https://openalex.org/W2153522384","doi":"https://doi.org/10.1109/tsmcc.2011.2172939","title":"Predicting DNA Motifs by Using Evolutionary Multiobjective Optimization","display_name":"Predicting DNA Motifs by Using Evolutionary Multiobjective Optimization","publication_year":2011,"publication_date":"2011-12-03","ids":{"openalex":"https://openalex.org/W2153522384","doi":"https://doi.org/10.1109/tsmcc.2011.2172939","mag":"2153522384"},"language":"en","primary_location":{"id":"doi:10.1109/tsmcc.2011.2172939","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tsmcc.2011.2172939","pdf_url":null,"source":{"id":"https://openalex.org/S4210227557","display_name":"IEEE Transactions on Systems Man and Cybernetics Part C (Applications and Reviews)","issn_l":"1094-6977","issn":["1094-6977","1558-2442"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Systems, Man, and Cybernetics, Part C (Applications and Reviews)","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111941806","display_name":"David L. Gonz\u00e1lez\u2010\u00c1lvarez","orcid":null},"institutions":[{"id":"https://openalex.org/I80606768","display_name":"Universidad de Extremadura","ror":"https://ror.org/0174shg90","country_code":"ES","type":"education","lineage":["https://openalex.org/I80606768"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"D. L. Gonzalez-\u00c1lvarez","raw_affiliation_strings":["Department of Technologies of Computers and Communications, University of Extremadura, C\u00e1ceres, Spain"],"affiliations":[{"raw_affiliation_string":"Department of Technologies of Computers and Communications, University of Extremadura, C\u00e1ceres, Spain","institution_ids":["https://openalex.org/I80606768"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049408851","display_name":"Miguel A. Vega\u2010Rodr\u00edguez","orcid":"https://orcid.org/0000-0002-3003-758X"},"institutions":[{"id":"https://openalex.org/I80606768","display_name":"Universidad de Extremadura","ror":"https://ror.org/0174shg90","country_code":"ES","type":"education","lineage":["https://openalex.org/I80606768"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M. A. Vega-Rodriguez","raw_affiliation_strings":["Department of Technologies of Computers and Communications, University of Extremadura, C\u00e1ceres, Spain"],"affiliations":[{"raw_affiliation_string":"Department of Technologies of Computers and Communications, University of Extremadura, C\u00e1ceres, Spain","institution_ids":["https://openalex.org/I80606768"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059757284","display_name":"Juan A. G\u00f3mez\u2010Pulido","orcid":"https://orcid.org/0000-0002-0441-9402"},"institutions":[{"id":"https://openalex.org/I80606768","display_name":"Universidad de Extremadura","ror":"https://ror.org/0174shg90","country_code":"ES","type":"education","lineage":["https://openalex.org/I80606768"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"J. A. Gomez-Pulido","raw_affiliation_strings":["Department of Technologies of Computers and Communications, University of Extremadura, C\u00e1ceres, Spain"],"affiliations":[{"raw_affiliation_string":"Department of Technologies of Computers and Communications, University of Extremadura, C\u00e1ceres, Spain","institution_ids":["https://openalex.org/I80606768"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103513190","display_name":"Juan M. S\u00e1nchez\u2010P\u00e9rez","orcid":null},"institutions":[{"id":"https://openalex.org/I80606768","display_name":"Universidad de Extremadura","ror":"https://ror.org/0174shg90","country_code":"ES","type":"education","lineage":["https://openalex.org/I80606768"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"J. M. Sanchez-P\u00e9rez","raw_affiliation_strings":["Department of Technologies of Computers and Communications, University of Extremadura, C\u00e1ceres, Spain"],"affiliations":[{"raw_affiliation_string":"Department of Technologies of Computers and Communications, University of Extremadura, C\u00e1ceres, Spain","institution_ids":["https://openalex.org/I80606768"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5111941806"],"corresponding_institution_ids":["https://openalex.org/I80606768"],"apc_list":null,"apc_paid":null,"fwci":3.766,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.93805072,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"42","issue":"6","first_page":"913","last_page":"925"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10848","display_name":"Advanced Multi-Objective Optimization Algorithms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10848","display_name":"Advanced Multi-Objective Optimization Algorithms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.995199978351593,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9926000237464905,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metaheuristic","display_name":"Metaheuristic","score":0.6768700480461121},{"id":"https://openalex.org/keywords/multi-objective-optimization","display_name":"Multi-objective optimization","score":0.6218271255493164},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.593610405921936},{"id":"https://openalex.org/keywords/motif","display_name":"Motif (music)","score":0.5168743133544922},{"id":"https://openalex.org/keywords/pareto-principle","display_name":"Pareto principle","score":0.49906468391418457},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.47924116253852844},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.452043354511261},{"id":"https://openalex.org/keywords/dna-binding-site","display_name":"DNA binding site","score":0.42697176337242126},{"id":"https://openalex.org/keywords/evolutionary-algorithm","display_name":"Evolutionary algorithm","score":0.4164649546146393},{"id":"https://openalex.org/keywords/dna-sequencing","display_name":"DNA sequencing","score":0.41437897086143494},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.35909634828567505},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.35054320096969604},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.29947900772094727},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2852039337158203},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.23796048760414124},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.22956371307373047},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.19979193806648254},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.10403665900230408},{"id":"https://openalex.org/keywords/promoter","display_name":"Promoter","score":0.07469761371612549}],"concepts":[{"id":"https://openalex.org/C109718341","wikidata":"https://www.wikidata.org/wiki/Q1385229","display_name":"Metaheuristic","level":2,"score":0.6768700480461121},{"id":"https://openalex.org/C68781425","wikidata":"https://www.wikidata.org/wiki/Q2052203","display_name":"Multi-objective optimization","level":2,"score":0.6218271255493164},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.593610405921936},{"id":"https://openalex.org/C32276052","wikidata":"https://www.wikidata.org/wiki/Q908349","display_name":"Motif (music)","level":2,"score":0.5168743133544922},{"id":"https://openalex.org/C137635306","wikidata":"https://www.wikidata.org/wiki/Q182667","display_name":"Pareto principle","level":2,"score":0.49906468391418457},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.47924116253852844},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.452043354511261},{"id":"https://openalex.org/C3662595","wikidata":"https://www.wikidata.org/wiki/Q5205743","display_name":"DNA binding site","level":5,"score":0.42697176337242126},{"id":"https://openalex.org/C159149176","wikidata":"https://www.wikidata.org/wiki/Q14489129","display_name":"Evolutionary algorithm","level":2,"score":0.4164649546146393},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.41437897086143494},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.35909634828567505},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.35054320096969604},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.29947900772094727},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2852039337158203},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.23796048760414124},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.22956371307373047},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19979193806648254},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10403665900230408},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.07469761371612549},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/tsmcc.2011.2172939","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tsmcc.2011.2172939","pdf_url":null,"source":{"id":"https://openalex.org/S4210227557","display_name":"IEEE Transactions on Systems Man and Cybernetics Part C (Applications and Reviews)","issn_l":"1094-6977","issn":["1094-6977","1558-2442"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Systems, Man, and Cybernetics, Part C (Applications and Reviews)","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W34145175","https://openalex.org/W1570624174","https://openalex.org/W1580213736","https://openalex.org/W1984057308","https://openalex.org/W1988393300","https://openalex.org/W1998300401","https://openalex.org/W2003967338","https://openalex.org/W2006138101","https://openalex.org/W2010334716","https://openalex.org/W2032231928","https://openalex.org/W2036131961","https://openalex.org/W2048869777","https://openalex.org/W2050824522","https://openalex.org/W2055030646","https://openalex.org/W2055214702","https://openalex.org/W2056002855","https://openalex.org/W2065715761","https://openalex.org/W2084908610","https://openalex.org/W2091230759","https://openalex.org/W2099612780","https://openalex.org/W2102941368","https://openalex.org/W2103055617","https://openalex.org/W2103691700","https://openalex.org/W2107700484","https://openalex.org/W2110455321","https://openalex.org/W2115269634","https://openalex.org/W2125899728","https://openalex.org/W2126105956","https://openalex.org/W2133412337","https://openalex.org/W2135729552","https://openalex.org/W2141408320","https://openalex.org/W2145295592","https://openalex.org/W2147055980","https://openalex.org/W2149312834","https://openalex.org/W2151638714","https://openalex.org/W2153654820","https://openalex.org/W2153988059","https://openalex.org/W2157120380","https://openalex.org/W2158266834","https://openalex.org/W2159831212","https://openalex.org/W2165212307","https://openalex.org/W2168157737","https://openalex.org/W4213242803","https://openalex.org/W6634719314"],"related_works":["https://openalex.org/W2001591765","https://openalex.org/W4241467429","https://openalex.org/W2863927645","https://openalex.org/W2145877535","https://openalex.org/W3151104768","https://openalex.org/W2147463381","https://openalex.org/W1536531504","https://openalex.org/W2117762792","https://openalex.org/W2044362008","https://openalex.org/W2075016777"],"abstract_inverted_index":{"Bioinformatics":[0],"and":[1,12,49,72,122],"computational":[2],"biology":[3],"include":[4],"researchers":[5],"from":[6,23],"many":[7,30],"areas:":[8],"biochemists,":[9],"physicists,":[10],"mathematicians,":[11],"engineers.":[13],"The":[14],"scale":[15],"of":[16,46,59,66,90,105,126],"the":[17,44,67,88,96,102,133,149,154,166,172,179],"problems":[18],"that":[19,136],"are":[20,139],"discussed":[21],"ranges":[22],"small":[24],"molecules":[25],"to":[26,94,101,148,175],"complex":[27],"systems,":[28],"where":[29],"organisms":[31],"coexist.":[32],"However,":[33],"among":[34],"all":[35],"these":[36,137],"issues,":[37],"we":[38,86,117,152,169],"can":[39],"highlight":[40],"genomics,":[41],"which":[42,157,188],"studies":[43],"genomes":[45],"microorganisms,":[47],"plants,":[48],"animals.":[50],"Predicting":[51],"common":[52],"patterns,":[53],"i.e.,":[54],"motifs,":[55],"in":[56,79,112,193],"a":[57,130],"set":[58],"deoxyribonucleic":[60],"acid":[61],"(DNA)":[62],"sequences":[63],"is":[64,178],"one":[65],"important":[68],"sequence":[69],"analysis":[70],"problems,":[71],"it":[73],"has":[74,158],"not":[75],"yet":[76],"been":[77,159,186],"resolved":[78],"an":[80],"efficient":[81],"manner.":[82],"In":[83],"this":[84],"study,":[85,132],"study":[87],"application":[89],"evolutionary":[91,163],"multiobjective":[92,127],"optimization":[93],"solve":[95],"motif":[97],"discovery":[98],"problem,":[99],"applied":[100],"specific":[103],"task":[104],"discovering":[106,142],"novel":[107],"transcription":[108],"factor":[109],"binding":[110],"sites":[111],"DNA":[113],"sequences.":[114],"For":[115],"this,":[116],"have":[118,185],"designed,":[119],"adapted,":[120],"configured,":[121],"evaluated":[123],"several":[124],"types":[125],"metaheuristics.":[128],"After":[129],"detailed":[131],"results":[134,184],"indicate":[135],"metaheuristics":[138],"appropriate":[140],"for":[141],"motifs.":[143],"To":[144],"find":[145],"good":[146],"approximations":[147],"Pareto":[150,181],"front,":[151],"use":[153,171],"hypervolume":[155,167],"indicator,":[156,168],"successfully":[160],"integrated":[161],"into":[162],"algorithms.":[164],"Besides":[165],"also":[170],"coverage":[173],"relation":[174],"ensure:":[176],"Which":[177],"best":[180],"front?":[182],"New":[183],"obtained,":[187],"significantly":[189],"improve":[190],"those":[191],"published":[192],"previous":[194],"research":[195],"works.":[196]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}