{"id":"https://openalex.org/W4383173614","doi":"https://doi.org/10.1109/tpami.2023.3292363","title":"Towards Causality-Aware Inferring: A Sequential Discriminative Approach for Medical Diagnosis","display_name":"Towards Causality-Aware Inferring: A Sequential Discriminative Approach for Medical Diagnosis","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W4383173614","doi":"https://doi.org/10.1109/tpami.2023.3292363","pmid":"https://pubmed.ncbi.nlm.nih.gov/37405895"},"language":"en","primary_location":{"id":"doi:10.1109/tpami.2023.3292363","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/tpami.2023.3292363","pdf_url":null,"source":{"id":"https://openalex.org/S199944782","display_name":"IEEE Transactions on Pattern Analysis and Machine Intelligence","issn_l":"0162-8828","issn":["0162-8828","1939-3539","2160-9292"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320439","host_organization_name":"IEEE Computer Society","host_organization_lineage":["https://openalex.org/P4310320439","https://openalex.org/P4310319808"],"host_organization_lineage_names":["IEEE Computer Society","Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Pattern Analysis and Machine Intelligence","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007186226","display_name":"Junfan Lin","orcid":"https://orcid.org/0000-0002-0099-6886"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Junfan Lin","raw_affiliation_strings":["School of Computer Science and Engineering, Sun Yat-sen University, Guangzhou, China","Engineering Research Center for Advanced Computing Engineering Software of the Ministry of Education, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Sun Yat-sen University, Guangzhou, China","institution_ids":["https://openalex.org/I157773358"]},{"raw_affiliation_string":"Engineering Research Center for Advanced Computing Engineering Software of the Ministry of Education, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088124671","display_name":"Keze Wang","orcid":"https://orcid.org/0000-0002-7817-8306"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Keze Wang","raw_affiliation_strings":["School of Computer Science and Engineering, Sun Yat-sen University, Guangzhou, China","Engineering Research Center for Advanced Computing Engineering Software of the Ministry of Education, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Sun Yat-sen University, Guangzhou, China","institution_ids":["https://openalex.org/I157773358"]},{"raw_affiliation_string":"Engineering Research Center for Advanced Computing Engineering Software of the Ministry of Education, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101601907","display_name":"Ziliang Chen","orcid":"https://orcid.org/0000-0003-2026-6028"},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ziliang Chen","raw_affiliation_strings":["Guangdong Institute of Smart Education, Jinan University, China"],"affiliations":[{"raw_affiliation_string":"Guangdong Institute of Smart Education, Jinan University, China","institution_ids":["https://openalex.org/I159948400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047878798","display_name":"Xiaodan Liang","orcid":"https://orcid.org/0000-0003-3213-3062"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaodan Liang","raw_affiliation_strings":["School of Intelligent Systems Engineering, Sun Yat-sen University, Guangzhou, China","Engineering Research Center for Advanced Computing Engineering Software of the Ministry of Education, China"],"affiliations":[{"raw_affiliation_string":"School of Intelligent Systems Engineering, Sun Yat-sen University, Guangzhou, China","institution_ids":["https://openalex.org/I157773358"]},{"raw_affiliation_string":"Engineering Research Center for Advanced Computing Engineering Software of the Ministry of Education, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100412937","display_name":"Liang Lin","orcid":"https://orcid.org/0000-0003-2248-3755"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Liang Lin","raw_affiliation_strings":["Engineering Research Center for Advanced Computing Engineering Software of the Ministry of Education, China"],"affiliations":[{"raw_affiliation_string":"Engineering Research Center for Advanced Computing Engineering Software of the Ministry of Education, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5007186226"],"corresponding_institution_ids":["https://openalex.org/I157773358"],"apc_list":null,"apc_paid":null,"fwci":1.2179,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.83070224,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"45","issue":"11","first_page":"1","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10028","display_name":"Topic Modeling","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10456","display_name":"Multi-Agent Systems and Negotiation","score":0.9739999771118164,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6400676965713501},{"id":"https://openalex.org/keywords/causality","display_name":"Causality (physics)","score":0.6304356455802917},{"id":"https://openalex.org/keywords/matching","display_name":"Matching (statistics)","score":0.6080896258354187},{"id":"https://openalex.org/keywords/discriminative-model","display_name":"Discriminative model","score":0.5772000551223755},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.568668007850647},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5542635917663574},{"id":"https://openalex.org/keywords/task","display_name":"Task (project management)","score":0.4986443519592285},{"id":"https://openalex.org/keywords/causal-inference","display_name":"Causal inference","score":0.446725457906723},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3502994179725647},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.34926652908325195},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.14635500311851501},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.10411134362220764}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6400676965713501},{"id":"https://openalex.org/C64357122","wikidata":"https://www.wikidata.org/wiki/Q1149766","display_name":"Causality (physics)","level":2,"score":0.6304356455802917},{"id":"https://openalex.org/C165064840","wikidata":"https://www.wikidata.org/wiki/Q1321061","display_name":"Matching (statistics)","level":2,"score":0.6080896258354187},{"id":"https://openalex.org/C97931131","wikidata":"https://www.wikidata.org/wiki/Q5282087","display_name":"Discriminative model","level":2,"score":0.5772000551223755},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.568668007850647},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5542635917663574},{"id":"https://openalex.org/C2780451532","wikidata":"https://www.wikidata.org/wiki/Q759676","display_name":"Task (project management)","level":2,"score":0.4986443519592285},{"id":"https://openalex.org/C158600405","wikidata":"https://www.wikidata.org/wiki/Q5054566","display_name":"Causal inference","level":2,"score":0.446725457906723},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3502994179725647},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.34926652908325195},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14635500311851501},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.10411134362220764},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C201995342","wikidata":"https://www.wikidata.org/wiki/Q682496","display_name":"Systems engineering","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015984","descriptor_name":"Causality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015984","descriptor_name":"Causality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tpami.2023.3292363","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/tpami.2023.3292363","pdf_url":null,"source":{"id":"https://openalex.org/S199944782","display_name":"IEEE Transactions on Pattern Analysis and Machine Intelligence","issn_l":"0162-8828","issn":["0162-8828","1939-3539","2160-9292"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320439","host_organization_name":"IEEE Computer Society","host_organization_lineage":["https://openalex.org/P4310320439","https://openalex.org/P4310319808"],"host_organization_lineage_names":["IEEE Computer Society","Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Pattern Analysis and Machine Intelligence","raw_type":"journal-article"},{"id":"pmid:37405895","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37405895","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on pattern analysis and machine intelligence","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10","score":0.7099999785423279}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":73,"referenced_works":["https://openalex.org/W1511986666","https://openalex.org/W1673419196","https://openalex.org/W1953155912","https://openalex.org/W1990214804","https://openalex.org/W1994094188","https://openalex.org/W2003905926","https://openalex.org/W2036193982","https://openalex.org/W2045968318","https://openalex.org/W2049910836","https://openalex.org/W2062175565","https://openalex.org/W2097796257","https://openalex.org/W2103009569","https://openalex.org/W2127726843","https://openalex.org/W2127992265","https://openalex.org/W2132917208","https://openalex.org/W2143117649","https://openalex.org/W2143891888","https://openalex.org/W2145339207","https://openalex.org/W2150291618","https://openalex.org/W2155027007","https://openalex.org/W2155163959","https://openalex.org/W2290798512","https://openalex.org/W2466989778","https://openalex.org/W2571927164","https://openalex.org/W2617547828","https://openalex.org/W2783543950","https://openalex.org/W2788477667","https://openalex.org/W2798914047","https://openalex.org/W2807588596","https://openalex.org/W2886305736","https://openalex.org/W2896457183","https://openalex.org/W2903928064","https://openalex.org/W2906902945","https://openalex.org/W2909534157","https://openalex.org/W2949252816","https://openalex.org/W2951799221","https://openalex.org/W2952993422","https://openalex.org/W2963789888","https://openalex.org/W2964067469","https://openalex.org/W2964077278","https://openalex.org/W2967737057","https://openalex.org/W2987123286","https://openalex.org/W2997281057","https://openalex.org/W3008613063","https://openalex.org/W3023069629","https://openalex.org/W3035017890","https://openalex.org/W3035103424","https://openalex.org/W3035145964","https://openalex.org/W3035651653","https://openalex.org/W3097981474","https://openalex.org/W3123974754","https://openalex.org/W3195968524","https://openalex.org/W3216656735","https://openalex.org/W4290742115","https://openalex.org/W4298857966","https://openalex.org/W4312609624","https://openalex.org/W4313156423","https://openalex.org/W6636922523","https://openalex.org/W6637220762","https://openalex.org/W6637967152","https://openalex.org/W6640927224","https://openalex.org/W6683204974","https://openalex.org/W6685444567","https://openalex.org/W6731619401","https://openalex.org/W6734696739","https://openalex.org/W6747812028","https://openalex.org/W6752244597","https://openalex.org/W6755207826","https://openalex.org/W6756303580","https://openalex.org/W6757324869","https://openalex.org/W6757835162","https://openalex.org/W6757864324","https://openalex.org/W6763168094"],"related_works":["https://openalex.org/W2965546495","https://openalex.org/W4389116644","https://openalex.org/W2153315159","https://openalex.org/W3103844505","https://openalex.org/W259157601","https://openalex.org/W4205463238","https://openalex.org/W2574301230","https://openalex.org/W1547624382","https://openalex.org/W4320159092","https://openalex.org/W4213427734"],"abstract_inverted_index":{"Medical":[0],"diagnosis":[1,187,190,216],"assistant":[2],"(MDA)":[3],"aims":[4],"to":[5,11,56,91,129,152,161,163,200,218,222],"build":[6],"an":[7],"interactive":[8],"diagnostic":[9,54,225],"agent":[10,55,146,240],"sequentially":[12],"inquire":[13,153,219],"about":[14,220],"symptoms":[15,221],"for":[16,24,182],"discriminating":[17],"diseases.":[18],"However,":[19],"since":[20],"the":[21,32,44,47,53,61,86,93,140,145,155,164,178,193,202,205,209,215,224,230,244,260],"dialogue":[22],"records":[23,34],"building":[25,125],"a":[26,108,119,126,172],"patient":[27,87,127,194,231],"simulator":[28,88,128],"are":[29],"collected":[30,33,142],"passively,":[31],"might":[35,51,147],"be":[36],"deteriorated":[37],"by":[38,149,198,214],"some":[39,97],"task-unrelated":[40],"biases,":[41,71],"such":[42],"as":[43,229],"preference":[45],"of":[46,204,262],"collectors.":[48],"These":[49],"biases":[50],"hinder":[52],"capture":[57],"transportable":[58],"knowledge":[59],"from":[60,85],"simulator.":[62],"This":[63],"work":[64],"identifies":[65],"and":[66,76,105,185,196,258],"resolves":[67],"two":[68],"representative":[69],"non-causal":[70],"i.e.,":[72,113],"(i)":[73,83],"default-answer":[74],"bias":[75,104],"(ii)":[77,135],"distributional":[78],"inquiry":[79,184,206,210],"bias.":[80],"Specifically,":[81],"Bias":[82,134],"originates":[84],"which":[89,176,227],"tries":[90],"answer":[92,131],"unrecorded":[94,132],"inquiries":[95],"with":[96,139],"biased":[98],"default":[99],"answers.":[100],"To":[101,167],"eliminate":[102,201],"this":[103,168,235],"improve":[106,242],"upon":[107,243],"well-known":[109],"causal":[110],"inference":[111],"technique,":[112],"propensity":[114,121],"score":[115],"matching,":[116],"we":[117,170],"propose":[118,171],"novel":[120],"latent":[122],"matching":[123],"in":[124],"effectively":[130],"inquiries;":[133],"inherently":[136],"comes":[137],"along":[138],"passively":[141],"data":[143,157],"that":[144,251],"learn":[148],"remembering":[150],"what":[151],"within":[154],"training":[156],"while":[158],"not":[159],"able":[160],"generalize":[162],"out-of-distribution":[165,245],"cases.":[166],"end,":[169],"progressive":[173],"assurance":[174],"agent,":[175],"includes":[177],"dual":[179],"processes":[180],"accounting":[181],"symptom":[183],"disease":[186],"respectively.":[188],"The":[189],"process":[191,211,217],"pictures":[192],"mentally":[195],"probabilistically":[197],"intervention":[199],"effect":[203],"behavior.":[207],"And":[208],"is":[212],"driven":[213],"enhance":[223],"confidence":[226],"alters":[228],"distribution":[232],"changes.":[233],"In":[234],"cooperative":[236],"manner,":[237],"our":[238,252],"proposed":[239],"can":[241],"generalization":[246],"significantly.":[247],"Extensive":[248],"experiments":[249],"demonstrate":[250],"framework":[253],"achieves":[254],"new":[255],"state-of-the-art":[256],"performance":[257],"possesses":[259],"advantage":[261],"transportability.":[263]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-04-02T15:55:50.835912","created_date":"2025-10-10T00:00:00"}