{"id":"https://openalex.org/W4410809513","doi":"https://doi.org/10.1109/tnnls.2025.3568036","title":"RadCLIP: Enhancing Radiologic Image Analysis Through Contrastive Language\u2013Image Pretraining","display_name":"RadCLIP: Enhancing Radiologic Image Analysis Through Contrastive Language\u2013Image Pretraining","publication_year":2025,"publication_date":"2025-05-28","ids":{"openalex":"https://openalex.org/W4410809513","doi":"https://doi.org/10.1109/tnnls.2025.3568036","pmid":"https://pubmed.ncbi.nlm.nih.gov/40434863"},"language":"en","primary_location":{"id":"doi:10.1109/tnnls.2025.3568036","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tnnls.2025.3568036","pdf_url":null,"source":{"id":"https://openalex.org/S4210175523","display_name":"IEEE Transactions on Neural Networks and Learning Systems","issn_l":"2162-237X","issn":["2162-237X","2162-2388"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Neural Networks and Learning Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12498476/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000606753","display_name":"Zhixiu Lu","orcid":"https://orcid.org/0009-0000-9904-9741"},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhixiu Lu","raw_affiliation_strings":["Department of Radiology, Imaging Research Center, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA"],"raw_orcid":"https://orcid.org/0009-0000-9904-9741","affiliations":[{"raw_affiliation_string":"Department of Radiology, Imaging Research Center, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100440674","display_name":"Hailong Li","orcid":"https://orcid.org/0000-0002-5267-2875"},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hailong Li","raw_affiliation_strings":["Imaging Research Center, Department of Radiology, the Artificial Intelligence Imaging Research Center, Neurodevelopmental Disorders Prevention Center, Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA"],"raw_orcid":"https://orcid.org/0000-0002-5267-2875","affiliations":[{"raw_affiliation_string":"Imaging Research Center, Department of Radiology, the Artificial Intelligence Imaging Research Center, Neurodevelopmental Disorders Prevention Center, Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085962055","display_name":"Nehal A. Parikh","orcid":"https://orcid.org/0000-0002-1375-1247"},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nehal A. Parikh","raw_affiliation_strings":["Neurodevelopmental Disorders Prevention Center, Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA"],"raw_orcid":"https://orcid.org/0000-0002-1375-1247","affiliations":[{"raw_affiliation_string":"Neurodevelopmental Disorders Prevention Center, Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011185996","display_name":"Jonathan R. Dillman","orcid":"https://orcid.org/0000-0003-0124-0164"},"institutions":[{"id":"https://openalex.org/I92156820","display_name":"University of Cincinnati Medical Center","ror":"https://ror.org/02p72h367","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I92156820"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan R. Dillman","raw_affiliation_strings":["Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA"],"raw_orcid":"https://orcid.org/0000-0003-0124-0164","affiliations":[{"raw_affiliation_string":"Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA","institution_ids":["https://openalex.org/I92156820"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040059979","display_name":"Lili He","orcid":"https://orcid.org/0000-0002-5246-6107"},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lili He","raw_affiliation_strings":["Imaging Research Center, Department of Radiology, the Artificial Intelligence Imaging Research Center, Neurodevelopmental Disorders Prevention Center, Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA"],"raw_orcid":"https://orcid.org/0000-0002-5246-6107","affiliations":[{"raw_affiliation_string":"Imaging Research Center, Department of Radiology, the Artificial Intelligence Imaging Research Center, Neurodevelopmental Disorders Prevention Center, Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA","institution_ids":["https://openalex.org/I1285204247"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.0729,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.93802709,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"36","issue":"10","first_page":"17613","last_page":"17622"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.9413999915122986,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.6638287901878357},{"id":"https://openalex.org/keywords/contrastive-analysis","display_name":"Contrastive analysis","score":0.5009810924530029},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4426334500312805},{"id":"https://openalex.org/keywords/linguistics","display_name":"Linguistics","score":0.43164199590682983},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.42246460914611816},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.3756326735019684},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.36244961619377136},{"id":"https://openalex.org/keywords/philosophy","display_name":"Philosophy","score":0.07117199897766113}],"concepts":[{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.6638287901878357},{"id":"https://openalex.org/C2777629044","wikidata":"https://www.wikidata.org/wiki/Q614959","display_name":"Contrastive analysis","level":2,"score":0.5009810924530029},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4426334500312805},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.43164199590682983},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.42246460914611816},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.3756326735019684},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.36244961619377136},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.07117199897766113}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007802","descriptor_name":"Language","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007802","descriptor_name":"Language","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007802","descriptor_name":"Language","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007802","descriptor_name":"Language","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/tnnls.2025.3568036","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tnnls.2025.3568036","pdf_url":null,"source":{"id":"https://openalex.org/S4210175523","display_name":"IEEE Transactions on Neural Networks and Learning Systems","issn_l":"2162-237X","issn":["2162-237X","2162-2388"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Neural Networks and Learning Systems","raw_type":"journal-article"},{"id":"pmid:40434863","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40434863","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on neural networks and learning systems","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:12498476","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12498476/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Neural Netw Learn Syst","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:12498476","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12498476/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Neural Netw Learn Syst","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10","score":0.4699999988079071}],"awards":[{"id":"https://openalex.org/G1341050533","display_name":null,"funder_award_id":"R01-EB030582","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8726399932","display_name":null,"funder_award_id":"R01-EB029944","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W2108598243","https://openalex.org/W2592929672","https://openalex.org/W2906216422","https://openalex.org/W2914203365","https://openalex.org/W2963466845","https://openalex.org/W2979839221","https://openalex.org/W3003650457","https://openalex.org/W3035588244","https://openalex.org/W3094286186","https://openalex.org/W3138516171","https://openalex.org/W3159019058","https://openalex.org/W3201906559","https://openalex.org/W4223899585","https://openalex.org/W4226283877","https://openalex.org/W4288068240","https://openalex.org/W4312713789","https://openalex.org/W4312956471","https://openalex.org/W4317436377","https://openalex.org/W4321479797","https://openalex.org/W4324144441","https://openalex.org/W4365143687","https://openalex.org/W4381486916","https://openalex.org/W4383343032","https://openalex.org/W4385573131","https://openalex.org/W4386065554","https://openalex.org/W4386566421","https://openalex.org/W4386758381","https://openalex.org/W4386918813","https://openalex.org/W4387211014","https://openalex.org/W4387225969","https://openalex.org/W4387490536","https://openalex.org/W4388854793","https://openalex.org/W4399564385","https://openalex.org/W4402701904"],"related_works":["https://openalex.org/W2772917594","https://openalex.org/W2036807459","https://openalex.org/W2058170566","https://openalex.org/W2755342338","https://openalex.org/W2166024367","https://openalex.org/W3116076068","https://openalex.org/W2229312674","https://openalex.org/W2951359407","https://openalex.org/W2079911747","https://openalex.org/W1969923398"],"abstract_inverted_index":{"The":[0],"integration":[1],"of":[2,29,117,211],"artificial":[3],"intelligence":[4],"(AI)":[5],"with":[6,127,199],"radiology":[7],"signifies":[8],"a":[9,73,80,100,113,134,175,187,195],"transformative":[10],"era":[11],"in":[12,63,133,147,167],"medicine.":[13],"Vision":[14],"foundation":[15,189],"models":[16],"have":[17],"been":[18],"adopted":[19],"to":[20,85],"enhance":[21],"radiologic":[22,33,64,68,87,118,125,139,150,180,215],"imaging":[23],"analysis.":[24,89],"However,":[25],"the":[26,59,92],"inherent":[27],"complexities":[28],"2D":[30,205],"and":[31,57,109,153,165,207],"3D":[32],"data":[34],"present":[35],"unique":[36],"challenges":[37],"that":[38,78],"existing":[39],"models,":[40],"which":[41],"are":[42],"typically":[43],"pretrained":[44,111],"on":[45,91,191,213],"general":[46],"nonmedical":[47],"images,":[48,206],"do":[49],"not":[50],"adequately":[51],"address.":[52],"To":[53],"bridge":[54],"this":[55,192],"gap":[56],"harness":[58],"diagnostic":[60,163],"precision":[61],"required":[62],"imaging,":[65],"we":[66],"introduce":[67],"contrastive":[69,93],"language-image":[70,94],"pretraining":[71,82,95,122,184],"(RadCLIP):":[72],"cross-modal":[74,154],"vision-language":[75,81,188],"foundational":[76],"model":[77,190],"utilizes":[79],"(VLP)":[83],"framework":[84],"improve":[86],"image":[88,107,151],"Building":[90],"(CLIP)":[96],"approach,":[97],"RadCLIP":[98,185,212],"incorporates":[99],"slice":[101,196],"pooling":[102,197],"mechanism":[103,202],"designed":[104],"for":[105,138,161,203],"volumetric":[106],"analysis":[108],"is":[110],"using":[112],"large,":[114],"diverse":[115,179],"dataset":[116,177],"image-text":[119,155,182],"pairs.":[120],"This":[121],"effectively":[123],"aligns":[124],"images":[126],"their":[128],"corresponding":[129],"text":[130],"annotations,":[131],"resulting":[132],"robust":[135],"vision":[136],"backbone":[137],"imaging.":[140],"Extensive":[141],"experiments":[142],"demonstrate":[143],"RadCLIP's":[144],"superior":[145],"performance":[146],"both":[148],"unimodal":[149],"classification":[152],"matching,":[156],"underscoring":[157],"its":[158],"significant":[159],"promise":[160],"enhancing":[162],"accuracy":[164],"efficiency":[166],"clinical":[168],"settings.":[169],"Our":[170],"key":[171],"contributions":[172],"include":[173],"curating":[174],"large":[176],"featuring":[178],"2D/3D":[181],"pairs,":[183],"as":[186],"dataset,":[193],"developing":[194],"adapter":[198],"an":[200],"attention":[201],"integrating":[204],"conducting":[208],"comprehensive":[209],"evaluations":[210],"various":[214],"downstream":[216],"tasks.":[217]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}