{"id":"https://openalex.org/W4389961012","doi":"https://doi.org/10.1109/tnnls.2023.3341347","title":"MARML: Motif-Aware Deep Representation Learning in Multilayer Networks","display_name":"MARML: Motif-Aware Deep Representation Learning in Multilayer Networks","publication_year":2023,"publication_date":"2023-12-19","ids":{"openalex":"https://openalex.org/W4389961012","doi":"https://doi.org/10.1109/tnnls.2023.3341347","pmid":"https://pubmed.ncbi.nlm.nih.gov/38113155"},"language":"en","primary_location":{"id":"doi:10.1109/tnnls.2023.3341347","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tnnls.2023.3341347","pdf_url":null,"source":{"id":"https://openalex.org/S4210175523","display_name":"IEEE Transactions on Neural Networks and Learning Systems","issn_l":"2162-237X","issn":["2162-237X","2162-2388"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Neural Networks and Learning Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11557564/pdf/nihms-2020893.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100726923","display_name":"Da Zhang","orcid":"https://orcid.org/0000-0003-3321-1835"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Da Zhang","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Miami, Coral Gables, FL, USA","Department of Neurology, University of California at San Francisco, San Francisco, CA, USA"],"raw_orcid":"https://orcid.org/0000-0003-3321-1835","affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Miami, Coral Gables, FL, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Neurology, University of California at San Francisco, San Francisco, CA, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038550961","display_name":"Mansur R. Kabuka","orcid":"https://orcid.org/0000-0003-2516-7942"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mansur R. Kabuka","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Miami, Coral Gables, FL, USA"],"raw_orcid":"https://orcid.org/0000-0003-2516-7942","affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Miami, Coral Gables, FL, USA","institution_ids":["https://openalex.org/I145608581"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3842,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.55554902,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"35","issue":"9","first_page":"11649","last_page":"11660"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10064","display_name":"Complex Network Analysis Techniques","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10064","display_name":"Complex Network Analysis Techniques","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11273","display_name":"Advanced Graph Neural Networks","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12536","display_name":"Topological and Geometric Data Analysis","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/motif","display_name":"Motif (music)","score":0.8613706827163696},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.46713709831237793},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.45179933309555054},{"id":"https://openalex.org/keywords/network-motif","display_name":"Network motif","score":0.41677534580230713},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.41528528928756714},{"id":"https://openalex.org/keywords/cognitive-science","display_name":"Cognitive science","score":0.3452807366847992},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.3033785820007324},{"id":"https://openalex.org/keywords/art","display_name":"Art","score":0.1585683822631836},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.1450197994709015},{"id":"https://openalex.org/keywords/aesthetics","display_name":"Aesthetics","score":0.14447927474975586},{"id":"https://openalex.org/keywords/complex-network","display_name":"Complex network","score":0.10406246781349182}],"concepts":[{"id":"https://openalex.org/C32276052","wikidata":"https://www.wikidata.org/wiki/Q908349","display_name":"Motif (music)","level":2,"score":0.8613706827163696},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.46713709831237793},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.45179933309555054},{"id":"https://openalex.org/C60723933","wikidata":"https://www.wikidata.org/wiki/Q7001080","display_name":"Network motif","level":3,"score":0.41677534580230713},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.41528528928756714},{"id":"https://openalex.org/C188147891","wikidata":"https://www.wikidata.org/wiki/Q147638","display_name":"Cognitive science","level":1,"score":0.3452807366847992},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3033785820007324},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.1585683822631836},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.1450197994709015},{"id":"https://openalex.org/C107038049","wikidata":"https://www.wikidata.org/wiki/Q35986","display_name":"Aesthetics","level":1,"score":0.14447927474975586},{"id":"https://openalex.org/C34947359","wikidata":"https://www.wikidata.org/wiki/Q665189","display_name":"Complex network","level":2,"score":0.10406246781349182}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1109/tnnls.2023.3341347","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tnnls.2023.3341347","pdf_url":null,"source":{"id":"https://openalex.org/S4210175523","display_name":"IEEE Transactions on Neural Networks and Learning Systems","issn_l":"2162-237X","issn":["2162-237X","2162-2388"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Neural Networks and Learning Systems","raw_type":"journal-article"},{"id":"pmid:38113155","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38113155","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on neural networks and learning systems","raw_type":null},{"id":"pmh:oai:europepmc.org:11212252","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11557564","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11557564/pdf/nihms-2020893.pdf","source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:11557564","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11557564/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Neural Netw Learn Syst","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:11212252","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11557564","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11557564/pdf/nihms-2020893.pdf","source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2754703424","display_name":null,"funder_award_id":"R44 GM143996","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4290690937","display_name":null,"funder_award_id":"R44CA206782","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320309249","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4389961012.pdf","grobid_xml":"https://content.openalex.org/works/W4389961012.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W1888005072","https://openalex.org/W1972878774","https://openalex.org/W1995907191","https://openalex.org/W2004559608","https://openalex.org/W2015208937","https://openalex.org/W2033579242","https://openalex.org/W2046399560","https://openalex.org/W2071158443","https://openalex.org/W2076363162","https://openalex.org/W2100527889","https://openalex.org/W2123583562","https://openalex.org/W2124637492","https://openalex.org/W2132022337","https://openalex.org/W2133986066","https://openalex.org/W2151936673","https://openalex.org/W2153624566","https://openalex.org/W2154851992","https://openalex.org/W2161917555","https://openalex.org/W2163485494","https://openalex.org/W2247119764","https://openalex.org/W2289974125","https://openalex.org/W2342114889","https://openalex.org/W2393319904","https://openalex.org/W2543598748","https://openalex.org/W2607500032","https://openalex.org/W2735272571","https://openalex.org/W2787927827","https://openalex.org/W2790197930","https://openalex.org/W2797105966","https://openalex.org/W2798673265","https://openalex.org/W2801116648","https://openalex.org/W2895544589","https://openalex.org/W2896956537","https://openalex.org/W2903634148","https://openalex.org/W2914425291","https://openalex.org/W2937762029","https://openalex.org/W2952448092","https://openalex.org/W2962752269","https://openalex.org/W2962756421","https://openalex.org/W2963127791","https://openalex.org/W2964015378","https://openalex.org/W3003893414","https://openalex.org/W3008903937","https://openalex.org/W3037826211","https://openalex.org/W3093850691","https://openalex.org/W3098727933","https://openalex.org/W3104097132","https://openalex.org/W4246877238","https://openalex.org/W4293651439","https://openalex.org/W4365397291","https://openalex.org/W6678846912","https://openalex.org/W6744557953","https://openalex.org/W6748660260","https://openalex.org/W6966985351"],"related_works":["https://openalex.org/W2731899572","https://openalex.org/W3215138031","https://openalex.org/W3079957389","https://openalex.org/W3009238340","https://openalex.org/W4321369474","https://openalex.org/W4360585206","https://openalex.org/W4285208911","https://openalex.org/W3082895349","https://openalex.org/W4213079790","https://openalex.org/W2248239756"],"abstract_inverted_index":{"The":[0,157],"rapid":[1],"increase":[2],"in":[3,50,75,108,163],"high-throughput,":[4],"complex,":[5],"and":[6,17,27,54,124,169,178,189],"heterogeneous":[7],"data":[8,23,58,78],"has":[9],"led":[10],"to":[11,29,33,35,39,62,79,166,174],"the":[12,103,135,182],"adoption":[13],"of":[14,68,91,184,197],"network-structured":[15],"models":[16],"analyses":[18],"for":[19,112],"interpretation.":[20],"However,":[21],"these":[22],"are":[24,59],"inherently":[25],"complex":[26,198],"challenging":[28],"understand,":[30],"prompting":[31],"researchers":[32],"turn":[34],"graph":[36],"embedding":[37,45,85],"methods":[38],"facilitate":[40],"analysis.":[41],"While":[42],"general":[43],"network":[44,114,141,191],"techniques":[46],"have":[47,72],"shown":[48],"promise":[49],"improving":[51],"downstream":[52],"prediction":[53,168],"classification":[55],"tasks,":[56],"real-world":[57],"complicated":[60],"due":[61],"cross-domain":[63],"interactions":[64,92],"between":[65,176],"different":[66,89,155],"types":[67,90],"entities.":[69],"Multilayered":[70],"networks":[71,111],"been":[73],"successful":[74],"integrating":[76],"biological":[77,81,199],"represent":[80],"systems'":[82],"hierarchy,":[83],"but":[84],"nodes":[86],"based":[87],"on":[88],"remains":[93],"an":[94],"unsolved":[95],"problem.":[96],"To":[97],"address":[98],"this":[99],"challenge,":[100],"we":[101,193],"propose":[102],"Motif-aware":[104],"deep":[105],"representation":[106],"learning":[107,113],"multilayer":[109,140],"(MARML)":[110],"representations.":[115],"Our":[116],"method":[117,137],"considers":[118,150],"recurring":[119],"motif":[120,147],"patterns,":[121],"topological":[122,190],"information,":[123,148],"attributive":[125],"information":[126],"from":[127],"other":[128],"sources":[129],"as":[130],"node":[131,187],"features.":[132],"We":[133],"validated":[134],"MARML":[136,149],"using":[138],"various":[139],"datasets.":[142],"In":[143],"addition,":[144],"by":[145],"incorporating":[146],"higher":[151],"order":[152],"connections":[153],"across":[154],"hierarchies.":[156],"learned":[158],"features":[159],"exhibited":[160],"excellent":[161],"accuracy":[162],"tasks":[164],"related":[165],"link":[167,170],"differentiation,":[171],"enabling":[172],"us":[173],"distinguish":[175],"existing":[177],"disconnected":[179],"triplets.":[180],"Through":[181],"integration":[183],"both":[185],"intrinsic":[186],"attributes":[188],"structures,":[192],"enhance":[194],"our":[195],"understanding":[196],"systems.":[200]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1}],"updated_date":"2026-08-01T09:00:35.917206","created_date":"2025-10-10T00:00:00"}