{"id":"https://openalex.org/W2745126627","doi":"https://doi.org/10.1109/tnnls.2017.2721448","title":"Model Approximation for Switched Genetic Regulatory Networks","display_name":"Model Approximation for Switched Genetic Regulatory Networks","publication_year":2017,"publication_date":"2017-08-07","ids":{"openalex":"https://openalex.org/W2745126627","doi":"https://doi.org/10.1109/tnnls.2017.2721448","mag":"2745126627","pmid":"https://pubmed.ncbi.nlm.nih.gov/28792906"},"language":"en","primary_location":{"id":"doi:10.1109/tnnls.2017.2721448","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tnnls.2017.2721448","pdf_url":null,"source":{"id":"https://openalex.org/S4210175523","display_name":"IEEE Transactions on Neural Networks and Learning Systems","issn_l":"2162-237X","issn":["2162-237X","2162-2388"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Neural Networks and Learning Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060187104","display_name":"Mengqi Xue","orcid":"https://orcid.org/0000-0002-1681-8865"},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mengqi Xue","raw_affiliation_strings":["Key Laboratory of Advanced Control and Optimization for Chemical Processes, Ministry of Education, East China University of Science and Technology, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0002-1681-8865","affiliations":[{"raw_affiliation_string":"Key Laboratory of Advanced Control and Optimization for Chemical Processes, Ministry of Education, East China University of Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I143593769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028570509","display_name":"Yang Tang","orcid":"https://orcid.org/0000-0002-2750-8029"},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Tang","raw_affiliation_strings":["Key Laboratory of Advanced Control and Optimization for Chemical Processes, Ministry of Education, East China University of Science and Technology, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0002-2750-8029","affiliations":[{"raw_affiliation_string":"Key Laboratory of Advanced Control and Optimization for Chemical Processes, Ministry of Education, East China University of Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I143593769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108047839","display_name":"Ligang Wu","orcid":"https://orcid.org/0000-0001-8198-5267"},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ligang Wu","raw_affiliation_strings":["Research Institute of Intelligent Control and Systems, Harbin Institute of Technology, Harbin, China"],"raw_orcid":"https://orcid.org/0000-0001-8198-5267","affiliations":[{"raw_affiliation_string":"Research Institute of Intelligent Control and Systems, Harbin Institute of Technology, Harbin, China","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100603023","display_name":"Feng Qian","orcid":"https://orcid.org/0000-0003-2781-332X"},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feng Qian","raw_affiliation_strings":["Key Laboratory of Advanced Control and Optimization for Chemical Processes, Ministry of Education, East China University of Science and Technology, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0003-2781-332X","affiliations":[{"raw_affiliation_string":"Key Laboratory of Advanced Control and Optimization for Chemical Processes, Ministry of Education, East China University of Science and Technology, Shanghai, China","institution_ids":["https://openalex.org/I143593769"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8974,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.73755535,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"29","issue":"8","first_page":"3404","last_page":"3417"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11236","display_name":"Control Systems and Identification","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2207","display_name":"Control and Systems Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9790999889373779,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bounding-overwatch","display_name":"Bounding overwatch","score":0.7222979068756104},{"id":"https://openalex.org/keywords/attenuation","display_name":"Attenuation","score":0.5685332417488098},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.5340216755867004},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.5091099143028259},{"id":"https://openalex.org/keywords/approximation-error","display_name":"Approximation error","score":0.5006000995635986},{"id":"https://openalex.org/keywords/approximation-algorithm","display_name":"Approximation algorithm","score":0.47473034262657166},{"id":"https://openalex.org/keywords/minification","display_name":"Minification","score":0.46493619680404663},{"id":"https://openalex.org/keywords/stability","display_name":"Stability (learning theory)","score":0.4573823809623718},{"id":"https://openalex.org/keywords/linear-approximation","display_name":"Linear approximation","score":0.43300697207450867},{"id":"https://openalex.org/keywords/dwell-time","display_name":"Dwell time","score":0.4144546389579773},{"id":"https://openalex.org/keywords/control-theory","display_name":"Control theory (sociology)","score":0.40066394209861755},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.398891806602478},{"id":"https://openalex.org/keywords/applied-mathematics","display_name":"Applied mathematics","score":0.34544503688812256},{"id":"https://openalex.org/keywords/nonlinear-system","display_name":"Nonlinear system","score":0.25256818532943726},{"id":"https://openalex.org/keywords/control","display_name":"Control (management)","score":0.12954717874526978}],"concepts":[{"id":"https://openalex.org/C63584917","wikidata":"https://www.wikidata.org/wiki/Q333286","display_name":"Bounding overwatch","level":2,"score":0.7222979068756104},{"id":"https://openalex.org/C184652730","wikidata":"https://www.wikidata.org/wiki/Q2357982","display_name":"Attenuation","level":2,"score":0.5685332417488098},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.5340216755867004},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.5091099143028259},{"id":"https://openalex.org/C122383733","wikidata":"https://www.wikidata.org/wiki/Q865920","display_name":"Approximation error","level":2,"score":0.5006000995635986},{"id":"https://openalex.org/C148764684","wikidata":"https://www.wikidata.org/wiki/Q621751","display_name":"Approximation algorithm","level":2,"score":0.47473034262657166},{"id":"https://openalex.org/C147764199","wikidata":"https://www.wikidata.org/wiki/Q6865248","display_name":"Minification","level":2,"score":0.46493619680404663},{"id":"https://openalex.org/C112972136","wikidata":"https://www.wikidata.org/wiki/Q7595718","display_name":"Stability (learning theory)","level":2,"score":0.4573823809623718},{"id":"https://openalex.org/C160824197","wikidata":"https://www.wikidata.org/wiki/Q2071054","display_name":"Linear approximation","level":3,"score":0.43300697207450867},{"id":"https://openalex.org/C151637689","wikidata":"https://www.wikidata.org/wiki/Q5318064","display_name":"Dwell time","level":2,"score":0.4144546389579773},{"id":"https://openalex.org/C47446073","wikidata":"https://www.wikidata.org/wiki/Q5165890","display_name":"Control theory (sociology)","level":3,"score":0.40066394209861755},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.398891806602478},{"id":"https://openalex.org/C28826006","wikidata":"https://www.wikidata.org/wiki/Q33521","display_name":"Applied mathematics","level":1,"score":0.34544503688812256},{"id":"https://openalex.org/C158622935","wikidata":"https://www.wikidata.org/wiki/Q660848","display_name":"Nonlinear system","level":2,"score":0.25256818532943726},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.12954717874526978},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tnnls.2017.2721448","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tnnls.2017.2721448","pdf_url":null,"source":{"id":"https://openalex.org/S4210175523","display_name":"IEEE Transactions on Neural Networks and Learning Systems","issn_l":"2162-237X","issn":["2162-237X","2162-2388"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Neural Networks and Learning Systems","raw_type":"journal-article"},{"id":"pmid:28792906","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28792906","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on neural networks and learning systems","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities","score":0.4099999964237213}],"awards":[{"id":"https://openalex.org/G1095201215","display_name":null,"funder_award_id":"141059","funder_id":"https://openalex.org/F4320326297","funder_display_name":"Fok Ying Tung Education Foundation"},{"id":"https://openalex.org/G2362846374","display_name":null,"funder_award_id":"61422303","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5123388924","display_name":null,"funder_award_id":"61525303","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7289406721","display_name":null,"funder_award_id":"61333010","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7619714573","display_name":null,"funder_award_id":"14ZR1410000","funder_id":"https://openalex.org/F4320309612","funder_display_name":"Natural Science Foundation of Shanghai"}],"funders":[{"id":"https://openalex.org/F4320309612","display_name":"Natural Science Foundation of Shanghai","ror":null},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320326297","display_name":"Fok Ying Tung Education Foundation","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W1195653569","https://openalex.org/W1535136082","https://openalex.org/W1645305843","https://openalex.org/W1783908245","https://openalex.org/W1895111777","https://openalex.org/W1965168231","https://openalex.org/W1987032998","https://openalex.org/W1994947552","https://openalex.org/W2001738877","https://openalex.org/W2007784570","https://openalex.org/W2016562720","https://openalex.org/W2036900244","https://openalex.org/W2037686415","https://openalex.org/W2039867272","https://openalex.org/W2043270542","https://openalex.org/W2062563339","https://openalex.org/W2062974796","https://openalex.org/W2064640535","https://openalex.org/W2066689921","https://openalex.org/W2067568029","https://openalex.org/W2075353843","https://openalex.org/W2082982706","https://openalex.org/W2100935517","https://openalex.org/W2102922646","https://openalex.org/W2112509480","https://openalex.org/W2120510384","https://openalex.org/W2134759932","https://openalex.org/W2139656224","https://openalex.org/W2145644212","https://openalex.org/W2156377786","https://openalex.org/W2162800561","https://openalex.org/W2165273705","https://openalex.org/W2170256406","https://openalex.org/W2188238115","https://openalex.org/W2319355247","https://openalex.org/W2326132599","https://openalex.org/W2342560477","https://openalex.org/W2344696031","https://openalex.org/W2395517654","https://openalex.org/W2409795543","https://openalex.org/W2444115642","https://openalex.org/W2962718458","https://openalex.org/W4236323066","https://openalex.org/W6671346601"],"related_works":["https://openalex.org/W2046314839","https://openalex.org/W2017216075","https://openalex.org/W2110817230","https://openalex.org/W3091355678","https://openalex.org/W3122413977","https://openalex.org/W1606488336","https://openalex.org/W96441109","https://openalex.org/W2037008369","https://openalex.org/W1988569331","https://openalex.org/W189995875"],"abstract_inverted_index":{"The":[0,59],"model":[1,24,106],"approximation":[2,42,83,107],"problem":[3,108,116],"is":[4,51,118],"studied":[5],"in":[6],"this":[7],"paper":[8],"for":[9,81,90,94],"switched":[10],"genetic":[11],"regulatory":[12],"networks":[13],"(GRNs)":[14],"with":[15,54],"time-varying":[16],"delays.":[17],"We":[18],"focus":[19],"on":[20],"constructing":[21],"a":[22,55,113],"reduced-order":[23,49,92],"to":[25,36,120,136],"approximate":[26],"the":[27,32,41,46,63,77,82,87,91,95,101,105,127,138,141,144],"high-order":[28],"GRNs":[29,96],"considered":[30],"under":[31],"switching":[33],"signal":[34],"subject":[35,119],"certain":[37],"constraints,":[38],"such":[39],"that":[40,117],"error":[43,84],"system":[44],"between":[45],"original":[47],"and":[48,62,76,140],"systems":[50],"exponentially":[52],"stable":[53],"disturbance":[56,64],"attenuation":[57,65],"performance.":[58],"stability":[60],"conditions":[61,89],"performance":[66],"are":[67,97,134],"established":[68,99],"by":[69,125],"utilizing":[70],"two":[71],"integral":[72],"inequality":[73,123],"bounding":[74],"techniques":[75],"average":[78],"dwell-time":[79],"method":[80],"system.":[85],"Then,":[86],"solvability":[88],"models":[93],"also":[98],"using":[100,126],"projection":[102],"method.":[103],"Furthermore,":[104],"can":[109],"be":[110],"transferred":[111],"into":[112],"sequential":[114],"minimization":[115],"linear":[121],"matrix":[122],"constraints":[124],"cone":[128],"complementarity":[129],"algorithm.":[130],"Finally,":[131],"several":[132],"examples":[133],"provided":[135],"illustrate":[137],"effectiveness":[139],"advantages":[142],"of":[143],"proposed":[145],"methods.":[146]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}