{"id":"https://openalex.org/W4409076917","doi":"https://doi.org/10.1109/tmi.2025.3556402","title":"CBCT Reconstruction Using Single X-Ray Projection With Cycle-Domain Geometry-Integrated Denoising Diffusion Probabilistic Models","display_name":"CBCT Reconstruction Using Single X-Ray Projection With Cycle-Domain Geometry-Integrated Denoising Diffusion Probabilistic Models","publication_year":2025,"publication_date":"2025-04-01","ids":{"openalex":"https://openalex.org/W4409076917","doi":"https://doi.org/10.1109/tmi.2025.3556402","pmid":"https://pubmed.ncbi.nlm.nih.gov/40168234"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2025.3556402","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2025.3556402","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055677011","display_name":"Shaoyan Pan","orcid":"https://orcid.org/0009-0007-1040-0189"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4390039307","display_name":"Winship Cancer Institute","ror":"https://ror.org/02gars961","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I4390039307"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Shaoyan Pan","raw_affiliation_strings":["Department of Radiation Oncology and Winship Cancer Institute, Department of Biomedical Informatics, Emory University, Atlanta, GA, USA","Department of Biomedical Informatics and the Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0009-0007-1040-0189","affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology and Winship Cancer Institute, Department of Biomedical Informatics, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Biomedical Informatics and the Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4390039307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103059319","display_name":"Junbo Peng","orcid":"https://orcid.org/0000-0002-5095-3016"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4390039307","display_name":"Winship Cancer Institute","ror":"https://ror.org/02gars961","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I4390039307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Junbo Peng","raw_affiliation_strings":["Department of Radiation Oncology and Winship Cancer Institute, Department of Biomedical Informatics, Emory University, Atlanta, GA, USA","Department of Biomedical Informatics and the Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology and Winship Cancer Institute, Department of Biomedical Informatics, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Biomedical Informatics and the Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4390039307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101781108","display_name":"Yuan Gao","orcid":"https://orcid.org/0000-0002-6988-4217"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4390039307","display_name":"Winship Cancer Institute","ror":"https://ror.org/02gars961","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I4390039307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuan Gao","raw_affiliation_strings":["Department of Radiation Oncology and Winship Cancer Institute, Department of Biomedical Informatics, Emory University, Atlanta, GA, USA","Department of Biomedical Informatics and the Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0000-0002-6988-4217","affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology and Winship Cancer Institute, Department of Biomedical Informatics, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Biomedical Informatics and the Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4390039307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073032555","display_name":"Shao-Yuan Lo","orcid":"https://orcid.org/0000-0002-9506-794X"},"institutions":[{"id":"https://openalex.org/I4210145184","display_name":"Honda (United States)","ror":"https://ror.org/04vdmc602","country_code":"US","type":"company","lineage":["https://openalex.org/I1283473643","https://openalex.org/I4210145184"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shao-Yuan Lo","raw_affiliation_strings":["Honda Research Institute USA, San Jose, CA, USA"],"raw_orcid":"https://orcid.org/0000-0002-9506-794X","affiliations":[{"raw_affiliation_string":"Honda Research Institute USA, San Jose, CA, USA","institution_ids":["https://openalex.org/I4210145184"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047400466","display_name":"Tianyu Luan","orcid":"https://orcid.org/0000-0001-7333-1052"},"institutions":[{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tianyu Luan","raw_affiliation_strings":["Department of Computer Science and Engineering, State University of New York at Buffalo, Amherst, NY, USA","State University of New York at Buffalo, Amherst, NY, USA"],"raw_orcid":"https://orcid.org/0000-0001-7333-1052","affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, State University of New York at Buffalo, Amherst, NY, USA","institution_ids":["https://openalex.org/I63190737"]},{"raw_affiliation_string":"State University of New York at Buffalo, Amherst, NY, USA","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057291490","display_name":"Junyuan Li","orcid":"https://orcid.org/0009-0005-7739-9341"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Junyuan Li","raw_affiliation_strings":["Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA","Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":"https://orcid.org/0009-0005-7739-9341","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049656223","display_name":"Tonghe Wang","orcid":"https://orcid.org/0000-0001-9021-1204"},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tonghe Wang","raw_affiliation_strings":["Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081954437","display_name":"Chih\u2010Wei Chang","orcid":"https://orcid.org/0000-0002-3818-4381"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4390039307","display_name":"Winship Cancer Institute","ror":"https://ror.org/02gars961","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I4390039307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chih-Wei Chang","raw_affiliation_strings":["Department of Radiation Oncology and Winship Cancer Institute, Department of Biomedical Informatics, Emory University, Atlanta, GA, USA","Department of Biomedical Informatics and the Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0000-0002-3818-4381","affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology and Winship Cancer Institute, Department of Biomedical Informatics, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Biomedical Informatics and the Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4390039307"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zhen Tian","orcid":"https://orcid.org/0000-0002-4098-5882"},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhen Tian","raw_affiliation_strings":["Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL, USA","Department of Radiation & Cellular Oncology, University of Chicago, Chicago, IL, USA"],"raw_orcid":"https://orcid.org/0000-0002-4098-5882","affiliations":[{"raw_affiliation_string":"Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL, USA","institution_ids":["https://openalex.org/I40347166"]},{"raw_affiliation_string":"Department of Radiation & Cellular Oncology, University of Chicago, Chicago, IL, USA","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100619090","display_name":"Xiaofeng Yang","orcid":"https://orcid.org/0000-0001-9023-5855"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4390039307","display_name":"Winship Cancer Institute","ror":"https://ror.org/02gars961","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I4390039307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaofeng Yang","raw_affiliation_strings":["Department of Radiation Oncology, the Department of Computer Science and Biomedical Informatics the Department of Biomedical Engineering and the Winship Cancer Institute, Emory University, Atlanta, GA, USA","Department of Radiation Oncology and Winship Cancer Institute, Department of Computer Science and Biomedical Informatics, and Department of Biomedical Engineering, Emory University, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0000-0001-9023-5855","affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, the Department of Computer Science and Biomedical Informatics the Department of Biomedical Engineering and the Winship Cancer Institute, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Radiation Oncology and Winship Cancer Institute, Department of Computer Science and Biomedical Informatics, and Department of Biomedical Engineering, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4390039307"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5055677011"],"corresponding_institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4390039307"],"apc_list":null,"apc_paid":null,"fwci":2.4034,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.87050785,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"44","issue":"7","first_page":"2933","last_page":"2947"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.9663000106811523,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/projection","display_name":"Projection (relational algebra)","score":0.6280844211578369},{"id":"https://openalex.org/keywords/probabilistic-logic","display_name":"Probabilistic logic","score":0.6134676933288574},{"id":"https://openalex.org/keywords/geometry","display_name":"Geometry","score":0.5297290682792664},{"id":"https://openalex.org/keywords/domain","display_name":"Domain (mathematical analysis)","score":0.5159097909927368},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5143088102340698},{"id":"https://openalex.org/keywords/noise-reduction","display_name":"Noise reduction","score":0.4864354133605957},{"id":"https://openalex.org/keywords/iterative-reconstruction","display_name":"Iterative reconstruction","score":0.483648419380188},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4349586069583893},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.43335139751434326},{"id":"https://openalex.org/keywords/diffusion","display_name":"Diffusion","score":0.4242340326309204},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.2812206745147705},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.27790337800979614},{"id":"https://openalex.org/keywords/mathematical-analysis","display_name":"Mathematical analysis","score":0.1678067445755005},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.13496160507202148}],"concepts":[{"id":"https://openalex.org/C57493831","wikidata":"https://www.wikidata.org/wiki/Q3134666","display_name":"Projection (relational algebra)","level":2,"score":0.6280844211578369},{"id":"https://openalex.org/C49937458","wikidata":"https://www.wikidata.org/wiki/Q2599292","display_name":"Probabilistic logic","level":2,"score":0.6134676933288574},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.5297290682792664},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.5159097909927368},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5143088102340698},{"id":"https://openalex.org/C163294075","wikidata":"https://www.wikidata.org/wiki/Q581861","display_name":"Noise reduction","level":2,"score":0.4864354133605957},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.483648419380188},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4349586069583893},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.43335139751434326},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.4242340326309204},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.2812206745147705},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.27790337800979614},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.1678067445755005},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.13496160507202148},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054893","descriptor_name":"Cone-Beam Computed Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D054893","descriptor_name":"Cone-Beam Computed Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D054893","descriptor_name":"Cone-Beam Computed Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D054893","descriptor_name":"Cone-Beam Computed Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D054893","descriptor_name":"Cone-Beam Computed Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tmi.2025.3556402","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2025.3556402","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:40168234","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40168234","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5099999904632568,"id":"https://metadata.un.org/sdg/11","display_name":"Sustainable cities and communities"}],"awards":[{"id":"https://openalex.org/G1873159316","display_name":null,"funder_award_id":"R01EB032680","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1956664977","display_name":null,"funder_award_id":"R01DE033512","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2777791002","display_name":null,"funder_award_id":"R01CA272991","funder_id":"https://openalex.org/F4320338403","funder_display_name":"Common Fund"},{"id":"https://openalex.org/G3329856668","display_name":null,"funder_award_id":"R01CA272991","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3850380546","display_name":null,"funder_award_id":"U54CA274513","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4285300191","display_name":null,"funder_award_id":"P30CA008748","funder_id":"https://openalex.org/F4320338403","funder_display_name":"Common Fund"},{"id":"https://openalex.org/G5037174621","display_name":null,"funder_award_id":"P30CA008748","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G539169519","display_name":null,"funder_award_id":"R01EB032680","funder_id":"https://openalex.org/F4320338403","funder_display_name":"Common Fund"},{"id":"https://openalex.org/G5430424462","display_name":null,"funder_award_id":"R56EB033332","funder_id":"https://openalex.org/F4320338403","funder_display_name":"Common Fund"},{"id":"https://openalex.org/G7122102308","display_name":null,"funder_award_id":"R56EB033332","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320338403","display_name":"Common Fund","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":54,"referenced_works":["https://openalex.org/W1972150100","https://openalex.org/W2094366314","https://openalex.org/W2111152057","https://openalex.org/W2143163922","https://openalex.org/W2149400409","https://openalex.org/W2164452299","https://openalex.org/W2165565866","https://openalex.org/W2743780012","https://openalex.org/W2745006834","https://openalex.org/W2791871435","https://openalex.org/W2808312419","https://openalex.org/W2894799553","https://openalex.org/W2941093521","https://openalex.org/W2962770929","https://openalex.org/W2962785568","https://openalex.org/W2962914239","https://openalex.org/W2963176524","https://openalex.org/W2963891322","https://openalex.org/W2963926543","https://openalex.org/W2964453626","https://openalex.org/W2982067315","https://openalex.org/W2995942064","https://openalex.org/W3034546843","https://openalex.org/W3035524985","https://openalex.org/W3093612132","https://openalex.org/W3133899621","https://openalex.org/W3135955764","https://openalex.org/W3138516171","https://openalex.org/W3163309171","https://openalex.org/W4200341256","https://openalex.org/W4288242633","https://openalex.org/W4296057829","https://openalex.org/W4296965639","https://openalex.org/W4297828509","https://openalex.org/W4312836452","https://openalex.org/W4327895829","https://openalex.org/W4381332772","https://openalex.org/W4386272462","https://openalex.org/W4386352882","https://openalex.org/W4387296387","https://openalex.org/W4387954532","https://openalex.org/W4389070723","https://openalex.org/W4390970420","https://openalex.org/W4395056684","https://openalex.org/W6678815747","https://openalex.org/W6779823529","https://openalex.org/W6783713337","https://openalex.org/W6788990321","https://openalex.org/W6790649466","https://openalex.org/W6795288823","https://openalex.org/W6809986647","https://openalex.org/W6843184996","https://openalex.org/W6850614898","https://openalex.org/W6853604127"],"related_works":["https://openalex.org/W2943623134","https://openalex.org/W2494523064","https://openalex.org/W2215759665","https://openalex.org/W2030292806","https://openalex.org/W2960358116","https://openalex.org/W2938171715","https://openalex.org/W4287727129","https://openalex.org/W2368237856","https://openalex.org/W2004988775","https://openalex.org/W2765479697"],"abstract_inverted_index":{"In":[0],"the":[1,33,61,117,125,155,174,251],"sphere":[2],"of":[3,98,212,231],"Cone":[4,142],"Beam":[5,143],"Computed":[6],"Tomography":[7],"(CBCT),":[8],"acquiring":[9],"X-ray":[10,144,186],"projections":[11,123,187],"from":[12,77,92,184,190,238],"sufficient":[13],"angles":[14],"is":[15,134,259],"indispensable":[16],"for":[17,32,47,84,119,127,253,262],"traditional":[18],"image":[19],"reconstruction":[20,160,213],"methods":[21,209],"to":[22,73,88,149,179,233],"accurately":[23],"reconstruct":[24,89,180],"3D":[25,90],"anatomical":[26],"intricacies.":[27],"However,":[28],"this":[29,57],"acquisition":[30],"procedure":[31],"linear":[34],"accelerator-mounted":[35],"CBCT":[36,91,96,107,129,181,237],"systems":[37],"in":[38,166,210],"radiotherapy":[39,263],"takes":[40],"approximately":[41],"one":[42],"minute,":[43],"impeding":[44],"its":[45,177],"use":[46],"ultra-fast":[48],"intra-fractional":[49],"motion":[50],"monitoring":[51],"during":[52,102],"treatment":[53,85],"delivery.":[54],"To":[55],"address":[56],"challenge,":[58],"we":[59],"introduce":[60],"Patient-specific":[62],"Cycle-domain":[63],"Geometric-integrated":[64],"Denoising":[65],"Diffusion":[66],"Probabilistic":[67],"Model":[68],"(CG-DDPM).":[69],"This":[70,218,258],"model":[71,249],"aims":[72],"leverage":[74],"patient-specific":[75],"priors":[76],"patient's":[78],"CT/4DCT":[79],"images,":[80],"which":[81],"are":[82],"acquired":[83],"planning":[86],"purposes,":[87],"a":[93,113,141,167,239,247],"single-view":[94,105,240],"2D":[95],"projection":[97,241],"any":[99,243],"arbitrary":[100,244],"angle":[101,245],"treatment,":[103],"namely":[104],"reconstructed":[106,236],"(svCBCT).":[108],"The":[109,193,229],"CG-DDPM":[110,194,232],"framework":[111],"encompasses":[112],"dual":[114,156],"DDPM":[115,208],"structure:":[116],"Projection-DDPM":[118],"synthesizing":[120],"comprehensive":[121],"full-view":[122],"and":[124,162,207,215,226,268],"CBCT-DDPM":[126],"creating":[128],"images.":[130],"A":[131],"key":[132],"innovation":[133],"our":[135],"Cycle-Domain":[136],"Geometry-Integrated":[137],"(CDGI)":[138],"method,":[139],"incorporating":[140],"Geometric":[145],"Transformation":[146],"Module":[147],"(GTM)":[148],"ensure":[150],"precise,":[151],"synergistic":[152],"operation":[153],"between":[154],"DDPMs,":[157],"thereby":[158],"enhancing":[159],"accuracy":[161],"reducing":[163],"artifacts.":[164],"Evaluated":[165],"study":[168],"involving":[169],"37":[170],"lung":[171],"cancer":[172,266],"patients,":[173],"method":[175],"demonstrated":[176],"ability":[178],"not":[182],"only":[183],"simulated":[185],"but":[188],"also":[189],"real-world":[191],"data.":[192],"significantly":[195],"outperforms":[196],"existing":[197],"V-shape":[198],"convolutional":[199],"neural":[200],"networks":[201],"(V-nets),":[202],"Generative":[203],"Adversarial":[204],"Networks":[205],"(GANs),":[206],"terms":[211],"fidelity":[214],"artifact":[216],"minimization.":[217],"was":[219],"confirmed":[220],"through":[221],"extensive":[222],"voxel-level,":[223],"structural,":[224],"visual,":[225],"clinical":[227],"assessments.":[228],"capability":[230],"generate":[234],"high-quality":[235],"at":[242,264],"using":[246],"single":[248],"opens":[250],"door":[252],"ultra-fast,":[254],"in-treatment":[255],"volumetric":[256],"imaging.":[257],"especially":[260],"beneficial":[261],"motion-associated":[265],"sites":[267],"image-guided":[269],"interventional":[270],"procedures.":[271]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}