{"id":"https://openalex.org/W4408609529","doi":"https://doi.org/10.1109/tmi.2025.3552692","title":"High Sensitivity Photoacoustic Imaging by Learning From Noisy Data","display_name":"High Sensitivity Photoacoustic Imaging by Learning From Noisy Data","publication_year":2025,"publication_date":"2025-03-19","ids":{"openalex":"https://openalex.org/W4408609529","doi":"https://doi.org/10.1109/tmi.2025.3552692","pmid":"https://pubmed.ncbi.nlm.nih.gov/40106247"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2025.3552692","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2025.3552692","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100385897","display_name":"Xu Tang","orcid":"https://orcid.org/0000-0001-9437-2662"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Xu Tang","raw_affiliation_strings":["Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, SAR, China","Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, China"],"raw_orcid":"https://orcid.org/0000-0001-9437-2662","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I168719708"]},{"raw_affiliation_string":"Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, China","institution_ids":["https://openalex.org/I168719708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087518458","display_name":"Jiangbo Chen","orcid":null},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Jiangbo Chen","raw_affiliation_strings":["Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, SAR, China","Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I168719708"]},{"raw_affiliation_string":"Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, China","institution_ids":["https://openalex.org/I168719708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053633341","display_name":"Zheng Qu","orcid":"https://orcid.org/0000-0003-1286-6058"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Zheng Qu","raw_affiliation_strings":["Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, SAR, China","Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, China"],"raw_orcid":"https://orcid.org/0000-0003-1286-6058","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I168719708"]},{"raw_affiliation_string":"Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, China","institution_ids":["https://openalex.org/I168719708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101574869","display_name":"Jingyi Zhu","orcid":"https://orcid.org/0000-0002-3005-6131"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Jingyi Zhu","raw_affiliation_strings":["Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, SAR, China","Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, China"],"raw_orcid":"https://orcid.org/0000-0002-3005-6131","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I168719708"]},{"raw_affiliation_string":"Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, China","institution_ids":["https://openalex.org/I168719708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040557926","display_name":"Mohammadreza Amjadian","orcid":"https://orcid.org/0000-0003-4404-7815"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Mohammadreza Amjadian","raw_affiliation_strings":["Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, SAR, China","Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I168719708"]},{"raw_affiliation_string":"Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, China","institution_ids":["https://openalex.org/I168719708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101802212","display_name":"Mingxuan Yang","orcid":"https://orcid.org/0000-0001-5141-6290"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Mingxuan Yang","raw_affiliation_strings":["Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, SAR, China","Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, China"],"raw_orcid":"https://orcid.org/0000-0001-5141-6290","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I168719708"]},{"raw_affiliation_string":"Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, China","institution_ids":["https://openalex.org/I168719708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055075769","display_name":"Yingpeng Wan","orcid":"https://orcid.org/0000-0003-1432-9424"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Yingpeng Wan","raw_affiliation_strings":["Department of Chemistry, Center of Super-Diamond and Advanced Films (COSDAF), City University of Hong Kong, Hong Kong, SAR, China","Department of Chemistry, Center of Super-Diamond and Advanced Films (COSDAF), City University of Hong Kong, Kowloon, Hong Kong SAR, P. R. China"],"raw_orcid":"https://orcid.org/0000-0003-1432-9424","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Center of Super-Diamond and Advanced Films (COSDAF), City University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I168719708"]},{"raw_affiliation_string":"Department of Chemistry, Center of Super-Diamond and Advanced Films (COSDAF), City University of Hong Kong, Kowloon, Hong Kong SAR, P. R. China","institution_ids":["https://openalex.org/I168719708"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078864574","display_name":"Lidai Wang","orcid":"https://orcid.org/0000-0003-3463-0740"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Lidai Wang","raw_affiliation_strings":["Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, SAR, China","Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, China"],"raw_orcid":"https://orcid.org/0000-0003-3463-0740","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I168719708"]},{"raw_affiliation_string":"Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, China","institution_ids":["https://openalex.org/I168719708"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I168719708"],"apc_list":null,"apc_paid":null,"fwci":2.1114,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.85781488,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"44","issue":"7","first_page":"2868","last_page":"2877"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11856","display_name":"Thermography and Photoacoustic Techniques","score":0.9933000206947327,"subfield":{"id":"https://openalex.org/subfields/2211","display_name":"Mechanics of Materials"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.9703999757766724,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sensitivity","display_name":"Sensitivity (control systems)","score":0.6637296080589294},{"id":"https://openalex.org/keywords/photoacoustic-imaging-in-biomedicine","display_name":"Photoacoustic imaging in biomedicine","score":0.6094101667404175},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.49734190106391907},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.49064722657203674},{"id":"https://openalex.org/keywords/medical-imaging","display_name":"Medical imaging","score":0.4324287474155426},{"id":"https://openalex.org/keywords/iterative-reconstruction","display_name":"Iterative reconstruction","score":0.4216829836368561},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.39722415804862976},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.25041496753692627},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.16409233212471008},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.08689409494400024}],"concepts":[{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.6637296080589294},{"id":"https://openalex.org/C54932901","wikidata":"https://www.wikidata.org/wiki/Q7187705","display_name":"Photoacoustic imaging in biomedicine","level":2,"score":0.6094101667404175},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.49734190106391907},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.49064722657203674},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.4324287474155426},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.4216829836368561},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.39722415804862976},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.25041496753692627},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.16409233212471008},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08689409494400024},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061088","descriptor_name":"Photoacoustic Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D061088","descriptor_name":"Photoacoustic Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D061088","descriptor_name":"Photoacoustic Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tmi.2025.3552692","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2025.3552692","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:40106247","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40106247","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4566182074","display_name":null,"funder_award_id":"62405093","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6171288897","display_name":null,"funder_award_id":"2023A1515110065","funder_id":"https://openalex.org/F4320337111","funder_display_name":"Basic and Applied Basic Research Foundation of Guangdong Province"},{"id":"https://openalex.org/G7282803097","display_name":null,"funder_award_id":"2023A1515110065","funder_id":"https://openalex.org/F4320320671","funder_display_name":"National Research Foundation"},{"id":"https://openalex.org/G7701535254","display_name":null,"funder_award_id":"81627805","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8086010527","display_name":null,"funder_award_id":"61805102","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320337111","display_name":"Basic and Applied Basic Research Foundation of Guangdong Province","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1974438823","https://openalex.org/W2019189459","https://openalex.org/W2026062752","https://openalex.org/W2077720339","https://openalex.org/W2089901886","https://openalex.org/W2283261814","https://openalex.org/W2565400716","https://openalex.org/W2613485993","https://openalex.org/W2808146670","https://openalex.org/W2893402254","https://openalex.org/W2898006103","https://openalex.org/W2963363021","https://openalex.org/W2974799347","https://openalex.org/W2995782734","https://openalex.org/W3025806813","https://openalex.org/W3036455158","https://openalex.org/W3080539213","https://openalex.org/W3091169880","https://openalex.org/W3093434218","https://openalex.org/W3114272149","https://openalex.org/W3119393341","https://openalex.org/W3126411932","https://openalex.org/W3133258136","https://openalex.org/W3185452917","https://openalex.org/W3208158563","https://openalex.org/W3208997990","https://openalex.org/W3209782513","https://openalex.org/W4220913108","https://openalex.org/W4220998694","https://openalex.org/W4280519662","https://openalex.org/W4283593657","https://openalex.org/W4296293035","https://openalex.org/W4303444720","https://openalex.org/W4309923227","https://openalex.org/W4311678933","https://openalex.org/W4312441397","https://openalex.org/W4380421810","https://openalex.org/W4381245501","https://openalex.org/W4385477380","https://openalex.org/W4390507857","https://openalex.org/W6749271710"],"related_works":["https://openalex.org/W3118253164","https://openalex.org/W2923010535","https://openalex.org/W4404080206","https://openalex.org/W2074827051","https://openalex.org/W1763364486","https://openalex.org/W2800744829","https://openalex.org/W2884876339","https://openalex.org/W4220763478","https://openalex.org/W2731062999","https://openalex.org/W3213584571"],"abstract_inverted_index":{"Photoacoustic":[0],"imaging":[1,7,132,164,169],"(PAI)":[2],"is":[3],"a":[4,14,87],"high-resolution":[5],"biomedical":[6,49],"technology":[8],"for":[9,114],"the":[10,38,94,142,155,163],"non-invasive":[11],"detection":[12],"of":[13,17,41,97,170],"broad":[15],"range":[16],"chromophores":[18],"at":[19],"multiple":[20],"scales":[21],"and":[22,55,124,166,184],"depths.":[23],"However,":[24],"limited":[25],"by":[26,158],"low":[27],"chromophore":[28],"concentration,":[29],"weak":[30],"signals":[31],"in":[32,47,53,149],"deep":[33,89,171],"tissue,":[34],"or":[35,76],"various":[36,130],"noise,":[37],"signal-to-noise":[39,95,156],"ratio":[40,96,157],"photoacoustic":[42,98,131],"images":[43,99],"may":[44],"be":[45,118,178],"compromised":[46],"many":[48,182],"applications.":[50,186],"Although":[51],"improvements":[52],"hardware":[54],"computational":[56],"methods":[57],"have":[58,66],"been":[59,68],"made":[60],"to":[61,72,79,92,160,181],"address":[62],"this":[63,105,175],"problem,":[64],"they":[65],"not":[67,108],"readily":[69,179],"available":[70],"due":[71],"either":[73],"high":[74],"costs":[75],"an":[77],"inability":[78],"generalize":[80],"across":[81,121],"different":[82],"datasets.":[83],"Here,":[84],"we":[85],"present":[86],"self-supervised":[88],"learning":[90],"method":[91,106,140,176],"increase":[93],"using":[100],"noisy":[101],"data":[102,113,127],"only.":[103],"Because":[104],"does":[107],"require":[109],"expensive":[110],"ground":[111],"truth":[112],"training,":[115],"it":[116],"can":[117,177],"easily":[119],"implemented":[120],"scanning":[122],"microscopic":[123],"computed":[125],"tomographic":[126],"acquired":[128],"with":[129],"systems.":[133],"In":[134],"vivo":[135],"results":[136],"show":[137],"that":[138,145],"our":[139],"makes":[141],"vascular":[143],"details":[144],"were":[146],"completely":[147],"submerged":[148],"noise":[150],"become":[151],"clearly":[152],"visible,":[153],"increases":[154],"up":[159],"12-fold,":[161],"doubles":[162],"depth,":[165],"enables":[167],"high-contrast":[168],"tumors.":[172],"We":[173],"believe":[174],"applied":[180],"preclinical":[183],"clinical":[185]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2}],"updated_date":"2025-12-28T23:10:05.387466","created_date":"2025-10-10T00:00:00"}