{"id":"https://openalex.org/W4406047462","doi":"https://doi.org/10.1109/tmi.2024.3525299","title":"Supervised Information Mining From Weakly Paired Images for Breast IHC Virtual Staining","display_name":"Supervised Information Mining From Weakly Paired Images for Breast IHC Virtual Staining","publication_year":2025,"publication_date":"2025-01-03","ids":{"openalex":"https://openalex.org/W4406047462","doi":"https://doi.org/10.1109/tmi.2024.3525299","pmid":"https://pubmed.ncbi.nlm.nih.gov/40030860"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2024.3525299","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2024.3525299","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110672258","display_name":"Xianchao Guan","orcid":null},"institutions":[{"id":"https://openalex.org/I158809036","display_name":"Shenzhen Institute of Information Technology","ror":"https://ror.org/03wrf9427","country_code":"CN","type":"education","lineage":["https://openalex.org/I158809036"]},{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xianchao Guan","raw_affiliation_strings":["School of Computer Science and Technology, Harbin Institute of Technology at Shenzhen, Shenzhen, China","Computer Science and Technology, Harbin Institute of Technology (Shenzhen), Shenzhen, SZ, CHN"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Harbin Institute of Technology at Shenzhen, Shenzhen, China","institution_ids":["https://openalex.org/I158809036","https://openalex.org/I204983213"]},{"raw_affiliation_string":"Computer Science and Technology, Harbin Institute of Technology (Shenzhen), Shenzhen, SZ, CHN","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100459168","display_name":"Zheng Zhang","orcid":"https://orcid.org/0000-0003-1470-6998"},"institutions":[{"id":"https://openalex.org/I158809036","display_name":"Shenzhen Institute of Information Technology","ror":"https://ror.org/03wrf9427","country_code":"CN","type":"education","lineage":["https://openalex.org/I158809036"]},{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zheng Zhang","raw_affiliation_strings":["School of Computer Science and Technology, Harbin Institute of Technology at Shenzhen, Shenzhen, China","Computer Science and Technology, Harbin Institute of Technology (Shenzhen), Shenzhen, SZ, CHN"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Harbin Institute of Technology at Shenzhen, Shenzhen, China","institution_ids":["https://openalex.org/I158809036","https://openalex.org/I204983213"]},{"raw_affiliation_string":"Computer Science and Technology, Harbin Institute of Technology (Shenzhen), Shenzhen, SZ, CHN","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089151617","display_name":"Yifeng Wang","orcid":"https://orcid.org/0000-0001-8317-8434"},"institutions":[{"id":"https://openalex.org/I158809036","display_name":"Shenzhen Institute of Information Technology","ror":"https://ror.org/03wrf9427","country_code":"CN","type":"education","lineage":["https://openalex.org/I158809036"]},{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yifeng Wang","raw_affiliation_strings":["School of Science, Harbin Institute of Technology at Shenzhen, Shenzhen, China","School of Science, Harbin Institute of Technology (Shenzhen), Shenzhen, SZ, CHN"],"affiliations":[{"raw_affiliation_string":"School of Science, Harbin Institute of Technology at Shenzhen, Shenzhen, China","institution_ids":["https://openalex.org/I158809036","https://openalex.org/I204983213"]},{"raw_affiliation_string":"School of Science, Harbin Institute of Technology (Shenzhen), Shenzhen, SZ, CHN","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101753750","display_name":"Yueheng Li","orcid":"https://orcid.org/0000-0003-1327-3334"},"institutions":[{"id":"https://openalex.org/I158809036","display_name":"Shenzhen Institute of Information Technology","ror":"https://ror.org/03wrf9427","country_code":"CN","type":"education","lineage":["https://openalex.org/I158809036"]},{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yueheng Li","raw_affiliation_strings":["School of Computer Science and Technology, Harbin Institute of Technology at Shenzhen, Shenzhen, China","Computer Science and Technology, Harbin Institute of Technology (Shenzhen), Shenzhen, SZ, CHN"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Harbin Institute of Technology at Shenzhen, Shenzhen, China","institution_ids":["https://openalex.org/I158809036","https://openalex.org/I204983213"]},{"raw_affiliation_string":"Computer Science and Technology, Harbin Institute of Technology (Shenzhen), Shenzhen, SZ, CHN","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101653272","display_name":"Yongbing Zhang","orcid":"https://orcid.org/0009-0008-1568-3728"},"institutions":[{"id":"https://openalex.org/I158809036","display_name":"Shenzhen Institute of Information Technology","ror":"https://ror.org/03wrf9427","country_code":"CN","type":"education","lineage":["https://openalex.org/I158809036"]},{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yongbing Zhang","raw_affiliation_strings":["School of Computer Science and Technology, Harbin Institute of Technology at Shenzhen, Shenzhen, China","Computer Science and Technology, Harbin Institute of Technology (Shenzhen), Shenzhen, SZ, CHN"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Harbin Institute of Technology at Shenzhen, Shenzhen, China","institution_ids":["https://openalex.org/I158809036","https://openalex.org/I204983213"]},{"raw_affiliation_string":"Computer Science and Technology, Harbin Institute of Technology (Shenzhen), Shenzhen, SZ, CHN","institution_ids":["https://openalex.org/I204983213"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5110672258"],"corresponding_institution_ids":["https://openalex.org/I158809036","https://openalex.org/I204983213"],"apc_list":null,"apc_paid":null,"fwci":14.141,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.9836948,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"44","issue":"5","first_page":"2120","last_page":"2130"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9772999882698059,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10824","display_name":"Image Retrieval and Classification Techniques","score":0.9555000066757202,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7266194224357605},{"id":"https://openalex.org/keywords/immunohistochemistry","display_name":"Immunohistochemistry","score":0.6255632042884827},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6192936301231384},{"id":"https://openalex.org/keywords/stain","display_name":"Stain","score":0.5879172086715698},{"id":"https://openalex.org/keywords/consistency","display_name":"Consistency (knowledge bases)","score":0.47232669591903687},{"id":"https://openalex.org/keywords/h-e-stain","display_name":"H&E stain","score":0.43964773416519165},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4236315190792084},{"id":"https://openalex.org/keywords/staining","display_name":"Staining","score":0.4201209247112274},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.295612633228302},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.22708731889724731}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7266194224357605},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.6255632042884827},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6192936301231384},{"id":"https://openalex.org/C2781294515","wikidata":"https://www.wikidata.org/wiki/Q2733470","display_name":"Stain","level":3,"score":0.5879172086715698},{"id":"https://openalex.org/C2776436953","wikidata":"https://www.wikidata.org/wiki/Q5163215","display_name":"Consistency (knowledge bases)","level":2,"score":0.47232669591903687},{"id":"https://openalex.org/C125473707","wikidata":"https://www.wikidata.org/wiki/Q9914","display_name":"H&E stain","level":3,"score":0.43964773416519165},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4236315190792084},{"id":"https://openalex.org/C74864618","wikidata":"https://www.wikidata.org/wiki/Q2332446","display_name":"Staining","level":2,"score":0.4201209247112274},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.295612633228302},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.22708731889724731}],"mesh":[{"descriptor_ui":"D000069553","descriptor_name":"Supervised Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069553","descriptor_name":"Supervised Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069553","descriptor_name":"Supervised Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069553","descriptor_name":"Supervised Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tmi.2024.3525299","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2024.3525299","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:40030860","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40030860","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G381440177","display_name":null,"funder_award_id":"HIT.OCEF.2023050","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G5217273760","display_name":null,"funder_award_id":"62031023","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5703881306","display_name":null,"funder_award_id":"62031023 & 62331011","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G656675884","display_name":null,"funder_award_id":"GXWD20220818170353009","funder_id":"https://openalex.org/F4320336569","funder_display_name":"Shenzhen Science and Technology Innovation Program"},{"id":"https://openalex.org/G7099010488","display_name":null,"funder_award_id":"HIT.OCEF.2023050","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8137439496","display_name":null,"funder_award_id":"62331011","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null},{"id":"https://openalex.org/F4320336569","display_name":"Shenzhen Science and Technology Innovation Program","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W2064076387","https://openalex.org/W2133665775","https://openalex.org/W2842511635","https://openalex.org/W2962793481","https://openalex.org/W2963073614","https://openalex.org/W2963079738","https://openalex.org/W2963767194","https://openalex.org/W2963800363","https://openalex.org/W3009330671","https://openalex.org/W3026766084","https://openalex.org/W3034600949","https://openalex.org/W3035037798","https://openalex.org/W3035242260","https://openalex.org/W3045198623","https://openalex.org/W3098491829","https://openalex.org/W3108316907","https://openalex.org/W3128646645","https://openalex.org/W3141929194","https://openalex.org/W3191728126","https://openalex.org/W4225010001","https://openalex.org/W4225985635","https://openalex.org/W4295936365","https://openalex.org/W4312696983","https://openalex.org/W4312709987","https://openalex.org/W4313413108","https://openalex.org/W4320483710","https://openalex.org/W4323037718","https://openalex.org/W4381684985","https://openalex.org/W4386121230","https://openalex.org/W4386327995","https://openalex.org/W4387211539","https://openalex.org/W4387640467","https://openalex.org/W4389065219","https://openalex.org/W4392754499","https://openalex.org/W4393317756","https://openalex.org/W4402373303","https://openalex.org/W4402774574","https://openalex.org/W6678815747","https://openalex.org/W6682962330","https://openalex.org/W6753914649","https://openalex.org/W6765779288","https://openalex.org/W6766150548"],"related_works":["https://openalex.org/W1705932695","https://openalex.org/W90289501","https://openalex.org/W2040366372","https://openalex.org/W2043390473","https://openalex.org/W3163749585","https://openalex.org/W4384826841","https://openalex.org/W4310665281","https://openalex.org/W4390098721","https://openalex.org/W4311305828","https://openalex.org/W2336199709"],"abstract_inverted_index":{"Immunohistochemistry":[0],"(IHC)":[1],"examination":[2],"is":[3,36,224],"essential":[4],"to":[5,24,50,59,74,113,214],"determine":[6],"the":[7,30,76,84,106,153,163,180,183,190,202,215],"tumour":[8],"subtypes,":[9],"provide":[10],"key":[11],"prognostic":[12],"factors,":[13],"and":[14,26,39,92,141,162,189,220],"develop":[15],"personalized":[16],"treatment":[17],"plans":[18],"for":[19,126],"breast":[20,127,209],"cancer.":[21],"However,":[22],"compared":[23,213],"Hematoxylin":[25],"Eosin":[27],"(H&E)":[28],"staining,":[29,130],"preparation":[31],"process":[32],"of":[33,83,204],"IHC":[34,51,61,93,128,167,187,194],"staining":[35],"more":[37,72],"complex":[38],"expensive,":[40],"which":[41,87,109,131],"limits":[42],"its":[43],"application":[44],"in":[45,155],"clinical":[46],"practice.":[47],"Therefore,":[48],"H&E":[49,91,160],"stain":[52],"transfer":[53],"may":[54],"be":[55,70],"an":[56,133],"ideal":[57],"solution":[58],"obtain":[60],"staining.":[62],"To":[63,116],"ensure":[64],"high":[65],"transferring":[66],"quality,":[67],"it":[68],"would":[69],"much":[71,171],"desirable":[73],"exploit":[75],"supervised":[77,136,145],"information":[78,137,146],"between":[79,159,182],"adjacent":[80,97,164],"layer":[81,98],"images":[82,100,161,188],"same":[85],"tissue,":[86],"are":[88,101],"stained":[89],"by":[90],"stainings,":[94],"respectively.":[95],"Nevertheless,":[96],"tissue":[99,210],"not":[102],"accurately":[103],"paired":[104],"at":[105,226],"pixel":[107],"level,":[108],"poses":[110],"significant":[111],"challenges":[112],"network":[114,125,154],"training.":[115],"address":[117],"this":[118],"problem,":[119],"we":[120],"propose":[121],"a":[122,142],"generative":[123],"adversarial":[124],"virtual":[129,186],"contains":[132],"optimal":[134],"transport-based":[135],"mining":[138,147,156],"(OT-SIM)":[139],"mechanism":[140],"pathological":[143],"correlation-based":[144],"(PC-SIM)":[148],"mechanism.":[149],"The":[150,176,222],"OT-SIM":[151],"guides":[152],"matching":[157],"consistency":[158,181],"layer's":[165],"real":[166,193],"images,":[168,195],"providing":[169,196],"as":[170,174],"instance-level":[172],"supervision":[173],"possible.":[175],"PC-SIM":[177],"further":[178],"explores":[179],"correlation":[184,191],"among":[185,192],"batch-level":[197],"supervision.":[198],"Extensive":[199],"experiments":[200],"show":[201],"superiority":[203],"our":[205],"method":[206],"on":[207],"two":[208],"benchmark":[211],"datasets":[212],"state-of-the-art":[216],"methods":[217],"both":[218],"quantitatively":[219],"qualitatively.":[221],"code":[223],"available":[225],"https://github.com/xianchaoguan/SIM-GAN.":[227]},"counts_by_year":[{"year":2025,"cited_by_count":6}],"updated_date":"2026-04-09T08:11:56.329763","created_date":"2025-10-10T00:00:00"}