{"id":"https://openalex.org/W4405936060","doi":"https://doi.org/10.1109/tmi.2024.3524253","title":"Imbalanced Medical Image Segmentation With Pixel-Dependent Noisy Labels","display_name":"Imbalanced Medical Image Segmentation With Pixel-Dependent Noisy Labels","publication_year":2024,"publication_date":"2024-12-31","ids":{"openalex":"https://openalex.org/W4405936060","doi":"https://doi.org/10.1109/tmi.2024.3524253","pmid":"https://pubmed.ncbi.nlm.nih.gov/40030766"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2024.3524253","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2024.3524253","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021341559","display_name":"Erjian Guo","orcid":"https://orcid.org/0000-0002-6406-2505"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Erjian Guo","raw_affiliation_strings":["School of Electrical and Computer Engineering, The University of Sydney, Sydney, NSW, Australia","School of Electrical and Computer Engineering, University of Sydney, Australia"],"affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, The University of Sydney, Sydney, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]},{"raw_affiliation_string":"School of Electrical and Computer Engineering, University of Sydney, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114500326","display_name":"Zicheng Wang","orcid":"https://orcid.org/0000-0002-4286-5120"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Zicheng Wang","raw_affiliation_strings":["School of Electrical and Computer Engineering, The University of Sydney, Sydney, NSW, Australia","School of Electrical and Computer Engineering, University of Sydney, Australia"],"affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, The University of Sydney, Sydney, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]},{"raw_affiliation_string":"School of Electrical and Computer Engineering, University of Sydney, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072694516","display_name":"Zhen Zhao","orcid":"https://orcid.org/0000-0002-0796-4078"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Zhen Zhao","raw_affiliation_strings":["School of Electrical and Computer Engineering, The University of Sydney, Sydney, NSW, Australia","School of Electrical and Computer Engineering, University of Sydney, Australia"],"affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, The University of Sydney, Sydney, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]},{"raw_affiliation_string":"School of Electrical and Computer Engineering, University of Sydney, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100643784","display_name":"Luping Zhou","orcid":"https://orcid.org/0000-0001-8762-2424"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Luping Zhou","raw_affiliation_strings":["School of Electrical and Computer Engineering, The University of Sydney, Sydney, NSW, Australia","School of Electrical and Computer Engineering, University of Sydney, Australia"],"affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, The University of Sydney, Sydney, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]},{"raw_affiliation_string":"School of Electrical and Computer Engineering, University of Sydney, Australia","institution_ids":["https://openalex.org/I129604602"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5021341559"],"corresponding_institution_ids":["https://openalex.org/I129604602"],"apc_list":null,"apc_paid":null,"fwci":1.0492,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.78507953,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"44","issue":"5","first_page":"2016","last_page":"2027"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9817000031471252,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9817000031471252,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12707","display_name":"Vehicle License Plate Recognition","score":0.9783999919891357,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9779000282287598,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7510648369789124},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.7213509678840637},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.7196478843688965},{"id":"https://openalex.org/keywords/pixel","display_name":"Pixel","score":0.6487202048301697},{"id":"https://openalex.org/keywords/medical-imaging","display_name":"Medical imaging","score":0.5742702484130859},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5658220052719116},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.5349729061126709},{"id":"https://openalex.org/keywords/scale-space-segmentation","display_name":"Scale-space segmentation","score":0.5347715020179749},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.4703775942325592},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4565834403038025},{"id":"https://openalex.org/keywords/segmentation-based-object-categorization","display_name":"Segmentation-based object categorization","score":0.4150046408176422}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7510648369789124},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.7213509678840637},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.7196478843688965},{"id":"https://openalex.org/C160633673","wikidata":"https://www.wikidata.org/wiki/Q355198","display_name":"Pixel","level":2,"score":0.6487202048301697},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.5742702484130859},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5658220052719116},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.5349729061126709},{"id":"https://openalex.org/C65885262","wikidata":"https://www.wikidata.org/wiki/Q7429708","display_name":"Scale-space segmentation","level":4,"score":0.5347715020179749},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.4703775942325592},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4565834403038025},{"id":"https://openalex.org/C25694479","wikidata":"https://www.wikidata.org/wiki/Q7446278","display_name":"Segmentation-based object categorization","level":5,"score":0.4150046408176422}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tmi.2024.3524253","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2024.3524253","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:40030766","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40030766","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W2412782625","https://openalex.org/W2510083763","https://openalex.org/W2963659419","https://openalex.org/W2964155802","https://openalex.org/W2981873476","https://openalex.org/W3006326483","https://openalex.org/W3009419078","https://openalex.org/W3024382584","https://openalex.org/W3034185248","https://openalex.org/W3035680157","https://openalex.org/W3036586801","https://openalex.org/W3091211922","https://openalex.org/W3096104140","https://openalex.org/W3171581326","https://openalex.org/W3173733742","https://openalex.org/W3175103763","https://openalex.org/W3182906273","https://openalex.org/W3202865535","https://openalex.org/W4281828860","https://openalex.org/W4282915608","https://openalex.org/W4283076748","https://openalex.org/W4286908677","https://openalex.org/W4287947470","https://openalex.org/W4288049163","https://openalex.org/W6736942654","https://openalex.org/W6740005241","https://openalex.org/W6747898760","https://openalex.org/W6751420435","https://openalex.org/W6758632346","https://openalex.org/W6758742486","https://openalex.org/W6763576130","https://openalex.org/W6773996751","https://openalex.org/W6786683507","https://openalex.org/W6790117478","https://openalex.org/W6796912519","https://openalex.org/W6802864417","https://openalex.org/W6849681138"],"related_works":["https://openalex.org/W3144569342","https://openalex.org/W2945274617","https://openalex.org/W2185902295","https://openalex.org/W2103507220","https://openalex.org/W2055202857","https://openalex.org/W4205800335","https://openalex.org/W2371519352","https://openalex.org/W2386644571","https://openalex.org/W2372421320","https://openalex.org/W2901890255"],"abstract_inverted_index":{"Accurate":[0],"medical":[1,19],"image":[2],"segmentation":[3,61,254],"is":[4,208,276],"often":[5],"hindered":[6],"by":[7,88],"noisy":[8,25,38,50,78,91,135,227],"labels":[9,26,79,92],"in":[10,263],"training":[11],"data,":[12],"due":[13],"to":[14,28,47,112,116,121,134,138,196,210,235,239],"the":[15,33,53,85,123,165,185,198,218,225,241],"challenges":[16],"of":[17,36,55,143,184,201,222,253],"annotating":[18],"images.":[20],"Prior":[21],"research":[22],"works":[23,87],"addressing":[24,96],"tend":[27],"make":[29],"class-dependent":[30],"assumptions,":[31],"overlooking":[32],"pixel-dependent":[34,77,94],"nature":[35],"most":[37],"labels.":[39],"Furthermore,":[40],"existing":[41,86],"methods":[42],"typically":[43],"apply":[44],"fixed":[45],"thresholds":[46],"filter":[48],"out":[49],"labels,":[51,228],"risking":[52],"removal":[54],"minority":[56],"classes":[57],"and":[58,95,103,127,159,194,271],"consequently":[59],"degrading":[60],"performance.":[62,242],"To":[63],"bridge":[64],"these":[65],"gaps,":[66],"our":[67,148,245],"proposed":[68],"framework,":[69,102],"Collaborative":[70],"Learning":[71],"with":[72,80,173,250],"Curriculum":[73,153],"Selection":[74,157],"(CLCS),":[75],"addresses":[76],"class":[81,124,199],"imbalance.":[82],"CLCS":[83,149,246],"advances":[84],"i)":[89],"treating":[90],"as":[93],"them":[97,145],"through":[98,214],"a":[99,106,130,170,204,232],"collaborative":[100,177],"learning":[101,114,178],"ii)":[104],"employing":[105],"curriculum":[107,205],"dynamic":[108,206],"thresholding":[109],"approach":[110],"adapting":[111],"model":[113],"progress":[115],"select":[117,211],"clean":[118],"data":[119,136,140],"samples":[120,137,213],"mitigate":[122],"imbalance":[125],"issue,":[126],"iii)":[128],"applying":[129],"noise":[131],"balance":[132],"loss":[133,175,234],"improve":[139],"utilization":[141],"instead":[142,221],"discarding":[144],"outright.":[146],"Specifically,":[147],"contains":[150],"two":[151,248],"modules:":[152],"Noisy":[154],"Label":[155],"Sample":[156],"(CNS)":[158],"Noise":[160],"Balance":[161],"Loss":[162],"(NBL).":[163],"In":[164,217],"CNS":[166],"module,":[167,220],"we":[168,229],"designed":[169],"two-branch":[171],"network":[172],"discrepancy":[174],"for":[176],"so":[179],"that":[180],"different":[181,251,264],"feature":[182],"representations":[183],"same":[186],"instance":[187],"could":[188],"be":[189],"extracted":[190],"from":[191],"distinct":[192],"views":[193],"used":[195],"vote":[197],"probabilities":[200],"pixels.":[202],"Besides,":[203],"threshold":[207],"adopted":[209],"clean-label":[212],"probability":[215],"voting.":[216],"NBL":[219],"directly":[223],"dropping":[224],"suspiciously":[226],"further":[230],"adopt":[231],"robust":[233],"leverage":[236],"such":[237],"instances":[238],"boost":[240],"We":[243],"verify":[244],"on":[247],"benchmarks":[249],"types":[252],"noise.":[255],"Our":[256,274],"method":[257],"can":[258],"obtain":[259],"new":[260],"state-of-the-art":[261],"performance":[262],"settings,":[265],"yielding":[266],"more":[267],"than":[268],"3%":[269],"Dice":[270],"mIoU":[272],"improvements.":[273],"code":[275],"available":[277],"at":[278],"https://github.com/Erjian96/CLCS.git.":[279]},"counts_by_year":[{"year":2025,"cited_by_count":4}],"updated_date":"2025-12-19T19:40:27.379048","created_date":"2025-10-10T00:00:00"}
