{"id":"https://openalex.org/W4391582558","doi":"https://doi.org/10.1109/tmi.2024.3362852","title":"Multi-Instance Multi-Task Learning for Joint Clinical Outcome and Genomic Profile Predictions From the Histopathological Images","display_name":"Multi-Instance Multi-Task Learning for Joint Clinical Outcome and Genomic Profile Predictions From the Histopathological Images","publication_year":2024,"publication_date":"2024-02-06","ids":{"openalex":"https://openalex.org/W4391582558","doi":"https://doi.org/10.1109/tmi.2024.3362852","pmid":"https://pubmed.ncbi.nlm.nih.gov/38319755"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2024.3362852","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2024.3362852","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076674630","display_name":"Wei Shao","orcid":"https://orcid.org/0000-0003-1476-2068"},"institutions":[{"id":"https://openalex.org/I9842412","display_name":"Nanjing University of Aeronautics and Astronautics","ror":"https://ror.org/01scyh794","country_code":"CN","type":"education","lineage":["https://openalex.org/I9842412"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Shao","raw_affiliation_strings":["College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China"],"raw_orcid":"https://orcid.org/0000-0003-1476-2068","affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China","institution_ids":["https://openalex.org/I9842412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028162489","display_name":"Hang Shi","orcid":"https://orcid.org/0000-0001-6472-3302"},"institutions":[{"id":"https://openalex.org/I9842412","display_name":"Nanjing University of Aeronautics and Astronautics","ror":"https://ror.org/01scyh794","country_code":"CN","type":"education","lineage":["https://openalex.org/I9842412"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hang Shi","raw_affiliation_strings":["College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China","institution_ids":["https://openalex.org/I9842412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015394916","display_name":"Jianxin Liu","orcid":"https://orcid.org/0000-0001-9395-4150"},"institutions":[{"id":"https://openalex.org/I9842412","display_name":"Nanjing University of Aeronautics and Astronautics","ror":"https://ror.org/01scyh794","country_code":"CN","type":"education","lineage":["https://openalex.org/I9842412"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianxin Liu","raw_affiliation_strings":["College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China","institution_ids":["https://openalex.org/I9842412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063561693","display_name":"Yingli Zuo","orcid":null},"institutions":[{"id":"https://openalex.org/I9842412","display_name":"Nanjing University of Aeronautics and Astronautics","ror":"https://ror.org/01scyh794","country_code":"CN","type":"education","lineage":["https://openalex.org/I9842412"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yingli Zuo","raw_affiliation_strings":["College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China","institution_ids":["https://openalex.org/I9842412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043777246","display_name":"Liang Sun","orcid":"https://orcid.org/0000-0003-2326-4802"},"institutions":[{"id":"https://openalex.org/I9842412","display_name":"Nanjing University of Aeronautics and Astronautics","ror":"https://ror.org/01scyh794","country_code":"CN","type":"education","lineage":["https://openalex.org/I9842412"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liang Sun","raw_affiliation_strings":["College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China"],"raw_orcid":"https://orcid.org/0000-0003-2326-4802","affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China","institution_ids":["https://openalex.org/I9842412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101301702","display_name":"Tiansong Xia","orcid":null},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tiansong Xia","raw_affiliation_strings":["First Affiliated Hospital of Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Affiliated Hospital of Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826","https://openalex.org/I4210152119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004424210","display_name":"Wanyuan Chen","orcid":"https://orcid.org/0000-0002-8216-9568"},"institutions":[{"id":"https://openalex.org/I4210165441","display_name":"Hangzhou Medical College","ror":"https://ror.org/05gpas306","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210165441"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wanyuan Chen","raw_affiliation_strings":["Department of Pathology, Cancer Center, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Cancer Center, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China","institution_ids":["https://openalex.org/I4210165441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077395936","display_name":"Peng Wan","orcid":"https://orcid.org/0000-0002-6094-7250"},"institutions":[{"id":"https://openalex.org/I9842412","display_name":"Nanjing University of Aeronautics and Astronautics","ror":"https://ror.org/01scyh794","country_code":"CN","type":"education","lineage":["https://openalex.org/I9842412"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peng Wan","raw_affiliation_strings":["College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China"],"raw_orcid":"https://orcid.org/0000-0002-6094-7250","affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China","institution_ids":["https://openalex.org/I9842412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060513618","display_name":"Jianpeng Sheng","orcid":"https://orcid.org/0000-0002-5535-5541"},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianpeng Sheng","raw_affiliation_strings":["First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101652370","display_name":"Qi Zhu","orcid":"https://orcid.org/0000-0001-5497-9478"},"institutions":[{"id":"https://openalex.org/I9842412","display_name":"Nanjing University of Aeronautics and Astronautics","ror":"https://ror.org/01scyh794","country_code":"CN","type":"education","lineage":["https://openalex.org/I9842412"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qi Zhu","raw_affiliation_strings":["College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China"],"raw_orcid":"https://orcid.org/0000-0001-5497-9478","affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China","institution_ids":["https://openalex.org/I9842412"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018821033","display_name":"Daoqiang Zhang","orcid":"https://orcid.org/0000-0002-5658-7643"},"institutions":[{"id":"https://openalex.org/I9842412","display_name":"Nanjing University of Aeronautics and Astronautics","ror":"https://ror.org/01scyh794","country_code":"CN","type":"education","lineage":["https://openalex.org/I9842412"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Daoqiang Zhang","raw_affiliation_strings":["College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China"],"raw_orcid":"https://orcid.org/0000-0002-5658-7643","affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, and the MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China","institution_ids":["https://openalex.org/I9842412"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.7234,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.95328575,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"43","issue":"6","first_page":"2266","last_page":"2278"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6531203985214233},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.638077974319458},{"id":"https://openalex.org/keywords/task","display_name":"Task (project management)","score":0.6126229166984558},{"id":"https://openalex.org/keywords/joint","display_name":"Joint (building)","score":0.5896933078765869},{"id":"https://openalex.org/keywords/outcome","display_name":"Outcome (game theory)","score":0.49133220314979553},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.45770713686943054},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1291002631187439},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.08151587843894958}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6531203985214233},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.638077974319458},{"id":"https://openalex.org/C2780451532","wikidata":"https://www.wikidata.org/wiki/Q759676","display_name":"Task (project management)","level":2,"score":0.6126229166984558},{"id":"https://openalex.org/C18555067","wikidata":"https://www.wikidata.org/wiki/Q8375051","display_name":"Joint (building)","level":2,"score":0.5896933078765869},{"id":"https://openalex.org/C148220186","wikidata":"https://www.wikidata.org/wiki/Q7111912","display_name":"Outcome (game theory)","level":2,"score":0.49133220314979553},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.45770713686943054},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1291002631187439},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08151587843894958},{"id":"https://openalex.org/C144237770","wikidata":"https://www.wikidata.org/wiki/Q747534","display_name":"Mathematical economics","level":1,"score":0.0},{"id":"https://openalex.org/C201995342","wikidata":"https://www.wikidata.org/wiki/Q682496","display_name":"Systems engineering","level":1,"score":0.0},{"id":"https://openalex.org/C170154142","wikidata":"https://www.wikidata.org/wiki/Q150737","display_name":"Architectural engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tmi.2024.3362852","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2024.3362852","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:38319755","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38319755","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1261530336","display_name":null,"funder_award_id":"62376123","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2320048606","display_name":null,"funder_award_id":"2023YFF1204803","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G3081035669","display_name":null,"funder_award_id":"62272226","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5293734332","display_name":null,"funder_award_id":"62076129","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6569153270","display_name":null,"funder_award_id":"2019YFA0803000","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G7869937607","display_name":null,"funder_award_id":"62136004","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8386303559","display_name":null,"funder_award_id":"62276130","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G85760107","display_name":null,"funder_award_id":"62371234","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W1969450298","https://openalex.org/W1978213837","https://openalex.org/W2049137769","https://openalex.org/W2064208261","https://openalex.org/W2092349886","https://openalex.org/W2103243046","https://openalex.org/W2117130368","https://openalex.org/W2344480160","https://openalex.org/W2514628397","https://openalex.org/W2745940724","https://openalex.org/W2752782242","https://openalex.org/W2753709519","https://openalex.org/W2753919178","https://openalex.org/W2761668583","https://openalex.org/W2769322745","https://openalex.org/W2884728705","https://openalex.org/W2890655214","https://openalex.org/W2963430933","https://openalex.org/W2963877604","https://openalex.org/W2964247799","https://openalex.org/W2966182616","https://openalex.org/W2980256439","https://openalex.org/W3034534840","https://openalex.org/W3035105468","https://openalex.org/W3043535018","https://openalex.org/W3044996171","https://openalex.org/W3085046840","https://openalex.org/W3128646645","https://openalex.org/W3133711868","https://openalex.org/W3141797743","https://openalex.org/W3176719058","https://openalex.org/W3178324441","https://openalex.org/W3201041614","https://openalex.org/W3203898052","https://openalex.org/W3210525534","https://openalex.org/W4206402984","https://openalex.org/W4210590194","https://openalex.org/W4214547251","https://openalex.org/W4220802999","https://openalex.org/W4225604175","https://openalex.org/W4288809219","https://openalex.org/W4296693015","https://openalex.org/W4306250152","https://openalex.org/W4309658701","https://openalex.org/W4312274013","https://openalex.org/W4360995290","https://openalex.org/W4365447146","https://openalex.org/W4367856046","https://openalex.org/W4379660110","https://openalex.org/W6803426362"],"related_works":["https://openalex.org/W2978999882","https://openalex.org/W3141031773","https://openalex.org/W1595686156","https://openalex.org/W2181392282","https://openalex.org/W2119369480","https://openalex.org/W148937441","https://openalex.org/W2153369162","https://openalex.org/W4367046737","https://openalex.org/W2033914206","https://openalex.org/W2042327336"],"abstract_inverted_index":{"With":[0],"the":[1,8,48,53,63,75,84,99,178,184,200,220],"remarkable":[2],"success":[3],"of":[4,62,87,223],"digital":[5],"histopathology":[6],"and":[7,146,218],"deep":[9,18,40,101],"learning":[10,19,41,102,125,140],"technology,":[11],"many":[12],"whole-slide":[13],"pathological":[14],"images":[15],"(WSIs)":[16],"based":[17,164],"models":[20],"are":[21,43],"designed":[22],"to":[23,46,97,153,173,181],"help":[24,182],"pathologists":[25],"diagnose":[26],"human":[27],"cancers.":[28],"Recently,":[29],"rather":[30],"than":[31,241],"predicting":[32,70],"categorical":[33],"variables":[34,50],"as":[35,52],"in":[36],"cancer":[37,196,214],"diagnosis,":[38,215],"several":[39],"studies":[42,65],"also":[44],"proposed":[45],"estimate":[47],"continuous":[49],"such":[51],"patients'":[54],"survival":[55,216],"or":[56],"their":[57],"transcriptional":[58,221],"profile.":[59],"However,":[60],"most":[61],"existing":[64],"focus":[66],"on":[67,187,194,236],"conducting":[68],"these":[69],"tasks":[71,152,180,211,240],"separately,":[72],"which":[73],"overlooks":[74],"useful":[76,175],"intrinsic":[77],"correlation":[78],"among":[79],"them":[80],"that":[81,230],"can":[82,232],"boost":[83],"prediction":[85,130,185,210,217,239],"performance":[86,186],"each":[88,158,206],"individual":[89,159],"task.":[90,160,189],"In":[91,116],"addition,":[92],"it":[93],"is":[94,107,171],"sill":[95],"challenge":[96],"design":[98],"WSI-based":[100],"models,":[103],"since":[104],"a":[105,121,137,162],"WSI":[106],"with":[108,113,167],"huge":[109],"size":[110],"but":[111],"annotated":[112],"coarse":[114],"label.":[115],"this":[117],"study,":[118],"we":[119,134],"propose":[120,136],"general":[122],"multi-instance":[123,139],"multi-task":[124],"framework":[126],"(HistMIMT)":[127],"for":[128,157],"multi-purpose":[129,209],"from":[131,177,199,213],"WSIs.":[132],"Specifically,":[133],"firstly":[135],"novel":[138],"module":[141,166],"(TMICS)":[142],"considering":[143],"both":[144],"common":[145],"specific":[147],"task":[148],"information":[149,176],"across":[150],"different":[151],"generate":[154],"bag":[155],"representation":[156],"Then,":[161],"soft-mask":[163],"fusion":[165],"channel":[168],"attention":[169],"(SFCA)":[170],"developed":[172],"leverage":[174],"related":[179],"improve":[183],"target":[188],"We":[190],"evaluate":[191],"our":[192,208],"method":[193],"three":[195],"cohorts":[197],"derived":[198],"Cancer":[201],"Genome":[202],"Atlas":[203],"(TCGA).":[204],"For":[205],"cohort,":[207],"range":[212],"estimating":[219],"profile":[222],"gene":[224],"TP53.":[225],"The":[226],"experimental":[227],"results":[228],"demonstrated":[229],"HistMIMT":[231],"yield":[233],"better":[234],"outcome":[235],"all":[237],"clinical":[238],"its":[242],"competitors.":[243]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}