{"id":"https://openalex.org/W4323338640","doi":"https://doi.org/10.1109/tmi.2023.3252576","title":"FDU-Net: Deep Learning-Based Three-Dimensional Diffuse Optical Image Reconstruction","display_name":"FDU-Net: Deep Learning-Based Three-Dimensional Diffuse Optical Image Reconstruction","publication_year":2023,"publication_date":"2023-03-06","ids":{"openalex":"https://openalex.org/W4323338640","doi":"https://doi.org/10.1109/tmi.2023.3252576","pmid":"https://pubmed.ncbi.nlm.nih.gov/37028063"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2023.3252576","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2023.3252576","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10446911/pdf/nihms-1921894.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101624787","display_name":"Bin Deng","orcid":"https://orcid.org/0000-0001-8347-1104"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bin Deng","raw_affiliation_strings":["Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital (MGH), Charlestown, MA, USA","Harvard Medical School (HMS), Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0001-8347-1104","affiliations":[{"raw_affiliation_string":"Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital (MGH), Charlestown, MA, USA","institution_ids":["https://openalex.org/I4210127055","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School (HMS), Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058205569","display_name":"Hanxue Gu","orcid":"https://orcid.org/0000-0003-2622-753X"},"institutions":[{"id":"https://openalex.org/I1311688040","display_name":"Amazon (United States)","ror":"https://ror.org/04mv4n011","country_code":"US","type":"company","lineage":["https://openalex.org/I1311688040"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hanxue Gu","raw_affiliation_strings":["Martinos Center, Massachusetts General Hospital (MGH), Charlestown, MA, USA","People Experience and Technology, Amazon.com Services LLC, Seattle, WA, USA","Department of Electrical and Computer Engineering, Duke University, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Martinos Center, Massachusetts General Hospital (MGH), Charlestown, MA, USA","institution_ids":["https://openalex.org/I4210127055","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"People Experience and Technology, Amazon.com Services LLC, Seattle, WA, USA","institution_ids":["https://openalex.org/I1311688040"]},{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Duke University, Durham, NC, USA","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100744403","display_name":"Hongmin Zhu","orcid":"https://orcid.org/0009-0000-8748-6178"},"institutions":[{"id":"https://openalex.org/I1311688040","display_name":"Amazon (United States)","ror":"https://ror.org/04mv4n011","country_code":"US","type":"company","lineage":["https://openalex.org/I1311688040"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hongmin Zhu","raw_affiliation_strings":["Martinos Center, Massachusetts General Hospital (MGH), Charlestown, MA, USA","People Experience and Technology, Amazon.com Services LLC, Seattle, WA, USA","Department of Electrical and Computer Engineering, Duke University, Durham, NC, USA"],"raw_orcid":"https://orcid.org/0009-0000-8748-6178","affiliations":[{"raw_affiliation_string":"Martinos Center, Massachusetts General Hospital (MGH), Charlestown, MA, USA","institution_ids":["https://openalex.org/I4210127055","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"People Experience and Technology, Amazon.com Services LLC, Seattle, WA, USA","institution_ids":["https://openalex.org/I1311688040"]},{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Duke University, Durham, NC, USA","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039622318","display_name":"Ken Chang","orcid":"https://orcid.org/0000-0001-6956-5059"},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ken Chang","raw_affiliation_strings":["Harvard-MIT Division of Health Sciences and Technology (HST), Massachusetts Institute of Technology (MIT), Cambridge, MA, USA","Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0001-6956-5059","affiliations":[{"raw_affiliation_string":"Harvard-MIT Division of Health Sciences and Technology (HST), Massachusetts Institute of Technology (MIT), Cambridge, MA, USA","institution_ids":["https://openalex.org/I4210092658","https://openalex.org/I63966007"]},{"raw_affiliation_string":"Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060793983","display_name":"Katharina Hoebel","orcid":"https://orcid.org/0000-0002-1881-7065"},"institutions":[{"id":"https://openalex.org/I1311688040","display_name":"Amazon (United States)","ror":"https://ror.org/04mv4n011","country_code":"US","type":"company","lineage":["https://openalex.org/I1311688040"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katharina V. Hoebel","raw_affiliation_strings":["People Experience and Technology, Amazon.com Services LLC, Seattle, WA, USA","Health Sciences and Technology (HST), Massachusetts Institute of Technology (MIT), Cambridge, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-1881-7065","affiliations":[{"raw_affiliation_string":"People Experience and Technology, Amazon.com Services LLC, Seattle, WA, USA","institution_ids":["https://openalex.org/I1311688040"]},{"raw_affiliation_string":"Health Sciences and Technology (HST), Massachusetts Institute of Technology (MIT), Cambridge, MA, USA","institution_ids":["https://openalex.org/I4210092658","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073840305","display_name":"Jay Patel","orcid":"https://orcid.org/0009-0000-2549-8341"},"institutions":[{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jay B. Patel","raw_affiliation_strings":["Health Sciences and Technology (HST), Massachusetts Institute of Technology (MIT), Cambridge, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health Sciences and Technology (HST), Massachusetts Institute of Technology (MIT), Cambridge, MA, USA","institution_ids":["https://openalex.org/I4210092658","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039535916","display_name":"Jayashree Kalpathy\u2013Cramer","orcid":"https://orcid.org/0000-0001-8906-9618"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz Medical Campus","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jayashree Kalpathy-Cramer","raw_affiliation_strings":["Martinos Center, Massachusetts General Hospital (MGH), Charlestown, MA, USA","Harvard Medical School (HMS), Boston, MA, USA","Department of Ophthalmology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Martinos Center, Massachusetts General Hospital (MGH), Charlestown, MA, USA","institution_ids":["https://openalex.org/I4210127055","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School (HMS), Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Ophthalmology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084602505","display_name":"Stefan A. Carp","orcid":"https://orcid.org/0000-0003-4617-3233"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stefan A. Carp","raw_affiliation_strings":["Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital (MGH), Charlestown, MA, USA","Harvard Medical School (HMS), Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0003-4617-3233","affiliations":[{"raw_affiliation_string":"Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital (MGH), Charlestown, MA, USA","institution_ids":["https://openalex.org/I4210127055","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Harvard Medical School (HMS), Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":6.1406,"has_fulltext":true,"cited_by_count":28,"citation_normalized_percentile":{"value":0.96904038,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"42","issue":"8","first_page":"2439","last_page":"2450"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12994","display_name":"Infrared Thermography in Medicine","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/iterative-reconstruction","display_name":"Iterative reconstruction","score":0.7134017944335938},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7074686288833618},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6980798244476318},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.6532372832298279},{"id":"https://openalex.org/keywords/subnet","display_name":"Subnet","score":0.6229228973388672},{"id":"https://openalex.org/keywords/diffuse-optical-imaging","display_name":"Diffuse optical imaging","score":0.5859218835830688},{"id":"https://openalex.org/keywords/image-quality","display_name":"Image quality","score":0.5435975790023804},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.4973457157611847},{"id":"https://openalex.org/keywords/ground-truth","display_name":"Ground truth","score":0.4134209454059601},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.37020230293273926},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.23473161458969116}],"concepts":[{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.7134017944335938},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7074686288833618},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6980798244476318},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.6532372832298279},{"id":"https://openalex.org/C21099817","wikidata":"https://www.wikidata.org/wiki/Q7631721","display_name":"Subnet","level":2,"score":0.6229228973388672},{"id":"https://openalex.org/C145417883","wikidata":"https://www.wikidata.org/wiki/Q5275421","display_name":"Diffuse optical imaging","level":3,"score":0.5859218835830688},{"id":"https://openalex.org/C55020928","wikidata":"https://www.wikidata.org/wiki/Q3813865","display_name":"Image quality","level":3,"score":0.5435975790023804},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4973457157611847},{"id":"https://openalex.org/C146849305","wikidata":"https://www.wikidata.org/wiki/Q370766","display_name":"Ground truth","level":2,"score":0.4134209454059601},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.37020230293273926},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.23473161458969116},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/tmi.2023.3252576","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2023.3252576","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:37028063","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37028063","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10446911","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10446911","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10446911/pdf/nihms-1921894.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Med Imaging","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:10446911","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10446911","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10446911/pdf/nihms-1921894.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Med Imaging","raw_type":"Text"},"sustainable_development_goals":[{"score":0.5299999713897705,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"}],"awards":[{"id":"https://openalex.org/G3613356276","display_name":null,"funder_award_id":"R01CA187595","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6023913522","display_name":null,"funder_award_id":"K01EB02772","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"}],"funders":[{"id":"https://openalex.org/F4320307759","display_name":"General Electric","ror":"https://ror.org/013msgt25"},{"id":"https://openalex.org/F4320309480","display_name":"Nvidia","ror":"https://ror.org/03jdj4y14"},{"id":"https://openalex.org/F4320332193","display_name":"Genentech","ror":"https://ror.org/04gndp242"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4323338640.pdf"},"referenced_works_count":61,"referenced_works":["https://openalex.org/W1522301498","https://openalex.org/W1780084781","https://openalex.org/W1901129140","https://openalex.org/W1973083020","https://openalex.org/W1979610482","https://openalex.org/W1980989869","https://openalex.org/W1987739106","https://openalex.org/W2003170314","https://openalex.org/W2008807821","https://openalex.org/W2018927311","https://openalex.org/W2021829136","https://openalex.org/W2032509868","https://openalex.org/W2058589748","https://openalex.org/W2061135416","https://openalex.org/W2075911794","https://openalex.org/W2080600885","https://openalex.org/W2090967583","https://openalex.org/W2095705004","https://openalex.org/W2122937330","https://openalex.org/W2133059825","https://openalex.org/W2139005519","https://openalex.org/W2140512870","https://openalex.org/W2143163067","https://openalex.org/W2161169693","https://openalex.org/W2226432548","https://openalex.org/W2289346088","https://openalex.org/W2292676122","https://openalex.org/W2460841889","https://openalex.org/W2464708700","https://openalex.org/W2507473942","https://openalex.org/W2560617851","https://openalex.org/W2568992596","https://openalex.org/W2574952845","https://openalex.org/W2584308697","https://openalex.org/W2609867678","https://openalex.org/W2611467245","https://openalex.org/W2762685704","https://openalex.org/W2765625483","https://openalex.org/W2803224943","https://openalex.org/W2805392478","https://openalex.org/W2892158776","https://openalex.org/W2905825954","https://openalex.org/W2919811351","https://openalex.org/W2927072297","https://openalex.org/W2953384591","https://openalex.org/W2969842883","https://openalex.org/W2985938182","https://openalex.org/W3014974815","https://openalex.org/W3027814546","https://openalex.org/W3047454941","https://openalex.org/W3098900881","https://openalex.org/W3100810380","https://openalex.org/W3112701542","https://openalex.org/W3193562516","https://openalex.org/W3194151683","https://openalex.org/W3207759772","https://openalex.org/W4206017534","https://openalex.org/W6631190155","https://openalex.org/W6674330103","https://openalex.org/W6713134421","https://openalex.org/W6800050843"],"related_works":["https://openalex.org/W2757389719","https://openalex.org/W3102052605","https://openalex.org/W2951714568","https://openalex.org/W1988158806","https://openalex.org/W1963814553","https://openalex.org/W2037595954","https://openalex.org/W2507293823","https://openalex.org/W2386146599","https://openalex.org/W2018015402","https://openalex.org/W1995070803"],"abstract_inverted_index":{"Near-infrared":[0],"diffuse":[1],"optical":[2,31],"tomography":[3],"(DOT)":[4],"is":[5,20,127],"a":[6,49,57,63,68,135,185,189],"promising":[7],"functional":[8],"modality":[9],"for":[10,70,108],"breast":[11,186,225,248],"cancer":[12],"imaging;":[13],"however,":[14],"the":[15,109,119,202,223,230,242],"clinical":[16,224,243],"translation":[17],"of":[18,56,91,122,214,247],"DOT":[19,74,204,239],"hampered":[21],"by":[22,62,125,238],"technical":[23],"limitations.":[24],"Specifically,":[25],"conventional":[26,112,203],"finite":[27],"element":[28],"method":[29],"(FEM)-based":[30],"image":[32,75,205],"reconstruction":[33,52,206],"approaches":[34],"are":[35],"time-consuming":[36],"and":[37,67,94,111,134,153,169,245],"ineffective":[38],"in":[39,100,217],"recovering":[40],"full":[41],"lesion":[42,236],"contrast.":[43],"To":[44],"address":[45],"this,":[46],"we":[47],"developed":[48],"deep":[50,195],"learning-based":[51,196],"model":[53,163],"(FDU-Net)":[54],"comprised":[55],"Fully":[58],"connected":[59],"subnet,":[60,66],"followed":[61],"convolutional":[64],"encoder-Decoder":[65],"U-Net":[69],"fast,":[71],"end-to-end":[72],"3D":[73],"reconstruction.":[76,161],"The":[77,162],"FDU-Net":[78,110,126,143,228],"was":[79,98,164],"trained":[80,178],"on":[81,179],"digital":[82],"phantoms":[83],"that":[84,118],"include":[85],"randomly":[86],"located":[87],"singular":[88],"spherical":[89],"inclusions":[90,172],"various":[92],"sizes":[93],"contrasts.":[95],"Reconstruction":[96],"performance":[97],"evaluated":[99],"400":[101],"simulated":[102,180],"cases":[103],"with":[104],"realistic":[105],"noise":[106],"profiles":[107],"FEM":[113],"approaches.":[114],"Our":[115],"results":[116],"show":[117],"overall":[120],"quality":[121],"images":[123],"reconstructed":[124],"significantly":[128],"improved":[129],"compared":[130],"to":[131,148,167,222,232,240],"FEM-based":[132],"methods":[133,207],"previously":[136],"proposed":[137],"deep-learning":[138],"network.":[139],"Importantly,":[140],"once":[141],"trained,":[142],"demonstrates":[144,198],"substantially":[145],"better":[146],"capability":[147],"recover":[149],"true":[150],"inclusion":[151,158],"contrast":[152],"location":[154],"without":[155],"using":[156],"any":[157],"information":[159],"during":[160,174],"also":[165,209],"generalizable":[166],"multi-focal":[168],"irregularly":[170],"shaped":[171],"unseen":[173],"training.":[175],"Finally,":[176],"FDU-Net,":[177],"data,":[181],"could":[182],"successfully":[183],"reconstruct":[184],"tumor":[187],"from":[188],"real":[190],"patient":[191],"measurement.":[192],"Overall,":[193],"our":[194],"approach":[197],"marked":[199],"superiority":[200],"over":[201,211],"while":[208],"offering":[210],"four":[212],"orders":[213],"magnitude":[215],"acceleration":[216],"computational":[218],"time.":[219],"Once":[220],"adapted":[221],"imaging":[226],"workflow,":[227],"has":[229],"potential":[231],"provide":[233],"real-time":[234],"accurate":[235],"characterization":[237],"assist":[241],"diagnosis":[244],"management":[246],"cancer.":[249]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":3}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}