{"id":"https://openalex.org/W4306732385","doi":"https://doi.org/10.1109/tmi.2022.3214344","title":"Multi-Scale Investigation of Human Renal Tissue in Three Dimensions","display_name":"Multi-Scale Investigation of Human Renal Tissue in Three Dimensions","publication_year":2022,"publication_date":"2022-11-03","ids":{"openalex":"https://openalex.org/W4306732385","doi":"https://doi.org/10.1109/tmi.2022.3214344","pmid":"https://pubmed.ncbi.nlm.nih.gov/36251918"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2022.3214344","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tmi.2022.3214344","pdf_url":"https://ieeexplore.ieee.org/ielx7/42/9969446/09921310.pdf","source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://ieeexplore.ieee.org/ielx7/42/9969446/09921310.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089351851","display_name":"Madleen Busse","orcid":"https://orcid.org/0000-0002-0114-2380"},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Busse","raw_affiliation_strings":["Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany"],"raw_orcid":"https://orcid.org/0000-0002-0114-2380","affiliations":[{"raw_affiliation_string":"Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085345966","display_name":"Simone Ferstl","orcid":null},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"S. Ferstl","raw_affiliation_strings":["Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","Veridos GmbH, Munich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Veridos GmbH, Munich, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077222008","display_name":"Melanie A. Kimm","orcid":"https://orcid.org/0000-0001-6833-9738"},"institutions":[{"id":"https://openalex.org/I2802619606","display_name":"TUM Klinikum","ror":"https://ror.org/04jc43x05","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802619606","https://openalex.org/I62916508"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. A. Kimm","raw_affiliation_strings":["Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany"],"raw_orcid":"https://orcid.org/0000-0001-6833-9738","affiliations":[{"raw_affiliation_string":"Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany","institution_ids":["https://openalex.org/I2802619606","https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067617381","display_name":"Lorenz Hehn","orcid":"https://orcid.org/0000-0003-4958-7036"},"institutions":[{"id":"https://openalex.org/I4210161922","display_name":"Brainlab (Germany)","ror":"https://ror.org/05ye48k35","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210161922"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"L. Hehn","raw_affiliation_strings":["Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","Brainlab AG, Munich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Brainlab AG, Munich, Germany","institution_ids":["https://openalex.org/I4210161922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001164379","display_name":"Katja Steiger","orcid":"https://orcid.org/0000-0002-7269-5433"},"institutions":[{"id":"https://openalex.org/I2802619606","display_name":"TUM Klinikum","ror":"https://ror.org/04jc43x05","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802619606","https://openalex.org/I62916508"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"K. Steiger","raw_affiliation_strings":["Department of Pathology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany","institution_ids":["https://openalex.org/I2802619606","https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075700136","display_name":"Sebastian Allner","orcid":null},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"S. Allner","raw_affiliation_strings":["Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","MITOS GmbH, Garching, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"MITOS GmbH, Garching, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101667185","display_name":"Mark M\u00fcller","orcid":null},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Muller","raw_affiliation_strings":["Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","SCANLAB GmbH, Puchheim, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"SCANLAB GmbH, Puchheim, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016089837","display_name":"Enken Drecoll","orcid":null},"institutions":[{"id":"https://openalex.org/I176453806","display_name":"University of Potsdam","ror":"https://ror.org/03bnmw459","country_code":"DE","type":"education","lineage":["https://openalex.org/I176453806"]},{"id":"https://openalex.org/I2802619606","display_name":"TUM Klinikum","ror":"https://ror.org/04jc43x05","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802619606","https://openalex.org/I62916508"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"E. Drecoll","raw_affiliation_strings":["Department of Pathology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany","Institute for Pathology, Labor Potsdam, Potsdam, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany","institution_ids":["https://openalex.org/I2802619606","https://openalex.org/I62916508"]},{"raw_affiliation_string":"Institute for Pathology, Labor Potsdam, Potsdam, Germany","institution_ids":["https://openalex.org/I176453806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014006414","display_name":"T. Burkner","orcid":null},"institutions":[{"id":"https://openalex.org/I4210121972","display_name":"Klinikum Ingolstadt","ror":"https://ror.org/035d65343","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210121972"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"T. Burkner","raw_affiliation_strings":["Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","Radiotherapy Ingolstadt, Ingolstadt, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Radiotherapy Ingolstadt, Ingolstadt, Germany","institution_ids":["https://openalex.org/I4210121972"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006070994","display_name":"Martin Dierolf","orcid":"https://orcid.org/0000-0001-5150-2949"},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Dierolf","raw_affiliation_strings":["Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany"],"raw_orcid":"https://orcid.org/0000-0001-5150-2949","affiliations":[{"raw_affiliation_string":"Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060716988","display_name":"Bernhard Gleich","orcid":"https://orcid.org/0000-0002-0574-7678"},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"B. Gleich","raw_affiliation_strings":["Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany"],"raw_orcid":"https://orcid.org/0000-0002-0574-7678","affiliations":[{"raw_affiliation_string":"Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018744564","display_name":"Wilko Weichert","orcid":"https://orcid.org/0000-0001-6139-8372"},"institutions":[{"id":"https://openalex.org/I2802619606","display_name":"TUM Klinikum","ror":"https://ror.org/04jc43x05","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802619606","https://openalex.org/I62916508"]},{"id":"https://openalex.org/I4391767962","display_name":"Deutsches Konsortium f\u00fcr Translationale Krebsforschung","ror":"https://ror.org/02pqn3g31","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4391767962","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"W. Weichert","raw_affiliation_strings":["Department of Pathology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany","German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany","institution_ids":["https://openalex.org/I2802619606","https://openalex.org/I62916508"]},{"raw_affiliation_string":"German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany","institution_ids":["https://openalex.org/I4391767962"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022885146","display_name":"Franz Pfeiffer","orcid":"https://orcid.org/0000-0001-6665-4363"},"institutions":[{"id":"https://openalex.org/I2802619606","display_name":"TUM Klinikum","ror":"https://ror.org/04jc43x05","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802619606","https://openalex.org/I62916508"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"F. Pfeiffer","raw_affiliation_strings":["Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany"],"raw_orcid":"https://orcid.org/0000-0001-6665-4363","affiliations":[{"raw_affiliation_string":"Department of Physics, School of Natural Sciences, Chair of Biomedical Physics, Munich Institute of Biomedical Engineering, Technical University of Munich, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany","institution_ids":["https://openalex.org/I2802619606","https://openalex.org/I62916508"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.2705,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.88566771,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"41","issue":"12","first_page":"3489","last_page":"3497"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11174","display_name":"Pediatric Urology and Nephrology Studies","score":0.9908000230789185,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11174","display_name":"Pediatric Urology and Nephrology Studies","score":0.9908000230789185,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11183","display_name":"Advanced X-ray Imaging Techniques","score":0.9898999929428101,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10606","display_name":"Kidney Stones and Urolithiasis Treatments","score":0.9876000285148621,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/voxel","display_name":"Voxel","score":0.5325713753700256},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5173810720443726},{"id":"https://openalex.org/keywords/scale","display_name":"Scale (ratio)","score":0.5054430961608887},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.46340513229370117},{"id":"https://openalex.org/keywords/medical-physics","display_name":"Medical physics","score":0.36866137385368347},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3493373990058899},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.3384931683540344},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3353472352027893},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.17166948318481445},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.1678437888622284}],"concepts":[{"id":"https://openalex.org/C54170458","wikidata":"https://www.wikidata.org/wiki/Q663554","display_name":"Voxel","level":2,"score":0.5325713753700256},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5173810720443726},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.5054430961608887},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.46340513229370117},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.36866137385368347},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3493373990058899},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3384931683540344},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3353472352027893},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17166948318481445},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1678437888622284},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004801","descriptor_name":"Eosine Yellowish-(YS)","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004801","descriptor_name":"Eosine Yellowish-(YS)","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004801","descriptor_name":"Eosine Yellowish-(YS)","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006652","descriptor_name":"Histological Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006652","descriptor_name":"Histological Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006652","descriptor_name":"Histological Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055114","descriptor_name":"X-Ray Microtomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055114","descriptor_name":"X-Ray Microtomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055114","descriptor_name":"X-Ray Microtomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1109/tmi.2022.3214344","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tmi.2022.3214344","pdf_url":"https://ieeexplore.ieee.org/ielx7/42/9969446/09921310.pdf","source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:36251918","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36251918","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null},{"id":"pmh:oai:mediatum.ub.tum.de:node/1692084","is_oa":false,"landing_page_url":"https://mediatum.ub.tum.de/1692084","pdf_url":null,"source":{"id":"https://openalex.org/S4306400453","display_name":"mediaTUM \u2013 the media and publications repository of the Technical University Munich (Technical University Munich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I62916508","host_organization_name":"Technical University of Munich","host_organization_lineage":["https://openalex.org/I62916508"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},{"id":"pmh:oai:mediatum.ub.tum.de:node/1694611","is_oa":false,"landing_page_url":"https://mediatum.ub.tum.de/1694611","pdf_url":null,"source":{"id":"https://openalex.org/S4306400453","display_name":"mediaTUM \u2013 the media and publications repository of the Technical University Munich (Technical University Munich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I62916508","host_organization_name":"Technical University of Munich","host_organization_lineage":["https://openalex.org/I62916508"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},{"id":"pmh:oai:mediatum.ub.tum.de:node/1772709","is_oa":true,"landing_page_url":"https://mediatum.ub.tum.de/1772709","pdf_url":null,"source":{"id":"https://openalex.org/S4377196330","display_name":"mediaTUM  (Technical University of Munich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I62916508","host_organization_name":"Technical University of Munich","host_organization_lineage":["https://openalex.org/I62916508"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"doi:10.1109/tmi.2022.3214344","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tmi.2022.3214344","pdf_url":"https://ieeexplore.ieee.org/ielx7/42/9969446/09921310.pdf","source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3097986083","display_name":null,"funder_award_id":"H2020-MSCA-IF-2015-703745-CONSALT","funder_id":"https://openalex.org/F4320338337","funder_display_name":"H2020 Marie Sk\u0142odowska-Curie Actions"},{"id":"https://openalex.org/G3313897312","display_name":null,"funder_award_id":"H2020-MSCA-IF-2015-703745-CONSALT","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G3345895242","display_name":null,"funder_award_id":"H2020-MSCA","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G5573126869","display_name":null,"funder_award_id":"H2020-MSCA-IF-2015","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"}],"funders":[{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320338337","display_name":"H2020 Marie Sk\u0142odowska-Curie Actions","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4306732385.pdf","grobid_xml":"https://content.openalex.org/works/W4306732385.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W652544941","https://openalex.org/W1963483517","https://openalex.org/W1965172991","https://openalex.org/W1973891017","https://openalex.org/W1980358325","https://openalex.org/W1985614502","https://openalex.org/W1989787675","https://openalex.org/W1997926517","https://openalex.org/W2016649008","https://openalex.org/W2038665424","https://openalex.org/W2039564097","https://openalex.org/W2070033826","https://openalex.org/W2093057354","https://openalex.org/W2110854390","https://openalex.org/W2136490577","https://openalex.org/W2136866695","https://openalex.org/W2157373537","https://openalex.org/W2161247859","https://openalex.org/W2163543028","https://openalex.org/W2167111693","https://openalex.org/W2407415032","https://openalex.org/W2444473664","https://openalex.org/W2754244961","https://openalex.org/W2767311458","https://openalex.org/W2788032313","https://openalex.org/W2792363490","https://openalex.org/W2806225253","https://openalex.org/W2903406340","https://openalex.org/W2904565695","https://openalex.org/W2945799185","https://openalex.org/W2975757730","https://openalex.org/W2981560996","https://openalex.org/W2986664747","https://openalex.org/W3004400661","https://openalex.org/W3009738277","https://openalex.org/W4236234523","https://openalex.org/W6654444058"],"related_works":["https://openalex.org/W2109867997","https://openalex.org/W2041273352","https://openalex.org/W2146871699","https://openalex.org/W2310750198","https://openalex.org/W2146691973","https://openalex.org/W2160739731","https://openalex.org/W2538301961","https://openalex.org/W3104625815","https://openalex.org/W2685530223","https://openalex.org/W2021379433"],"abstract_inverted_index":{"Histopathology":[0],"as":[1,24],"a":[2,10,39,97,137,141],"diagnostic":[3],"mainstay":[4],"for":[5,44,64,122,140,169],"tissue":[6,31,48,191],"evaluation":[7],"is":[8,149],"strictly":[9],"2D":[11],"technology.":[12],"Combining":[13],"and":[14,81,94,100,117,172],"supplementing":[15],"this":[16,34,184],"technology":[17],"with":[18,53,75,96,110,151,161],"3D":[19],"imaging":[20,171],"has":[21],"been":[22],"proposed":[23],"one":[25],"future":[26,181],"avenue":[27],"towards":[28],"refining":[29],"comprehensive":[30],"analysis.":[32],"To":[33,57],"end,":[35],"we":[36,67],"have":[37],"developed":[38],"laboratory-based":[40],"X-ray":[41,91],"method":[42,63,185],"allowing":[43,139,168],"the":[45,59,118],"investigation":[46,144],"of":[47,61,113,155],"samples":[49],"in":[50,145],"three":[51,73,146],"dimensions":[52,147],"isotropic":[54,174],"volume":[55,175],"information.":[56,176],"assess":[58],"potential":[60],"our":[62,89,101,156],"micro-morphology":[65],"evaluation,":[66],"selected":[68],"several":[69],"kidney":[70,77],"regions":[71],"from":[72,128],"patients":[74],"cystic":[76],"disease,":[78],"obstructive":[79],"nephropathy":[80],"diabetic":[82],"glomerulopathy.":[83],"Tissue":[84],"specimens":[85],"were":[86],"processed":[87],"using":[88],"in-house-developed":[90],"eosin":[92],"stain":[93],"investigated":[95],"commercial":[98],"microCT":[99,105],"in-house-built":[102],"NanoCT.":[103],"The":[104],"system":[106],"provided":[107],"overview":[108],"scans":[109],"voxel":[111,126],"sizes":[112,127],"[Formula:":[114,129],"see":[115,130],"text]":[116,131],"NanoCT":[119],"was":[120],"employed":[121],"higher":[123],"resolutions":[124],"including":[125],"to":[132,163,188],"210":[133],"nm.":[134],"We":[135,177],"present":[136],"methodology":[138,157],"precise":[142],"micro-morphologic":[143],"which":[148],"compatible":[150],"conventional":[152],"histology.":[153],"Advantages":[154],"are":[158],"its":[159],"versatility":[160],"respect":[162],"multi-scale":[164],"investigations,":[165],"being":[166],"laboratory-based,":[167],"non-destructive":[170],"providing":[173],"believe,":[178],"that":[179],"after":[180],"developmental":[182],"work":[183],"might":[186],"contribute":[187],"advanced":[189],"multi-modal":[190],"diagnostics.":[192]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
