{"id":"https://openalex.org/W3201393040","doi":"https://doi.org/10.1109/tmi.2021.3113365","title":"Content-Noise Complementary Learning for Medical Image Denoising","display_name":"Content-Noise Complementary Learning for Medical Image Denoising","publication_year":2021,"publication_date":"2021-09-16","ids":{"openalex":"https://openalex.org/W3201393040","doi":"https://doi.org/10.1109/tmi.2021.3113365","mag":"3201393040","pmid":"https://pubmed.ncbi.nlm.nih.gov/34529565"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2021.3113365","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2021.3113365","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060475920","display_name":"Mufeng Geng","orcid":"https://orcid.org/0000-0002-8995-6994"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210102541","display_name":"Shenzhen Bay Laboratory","ror":"https://ror.org/00sdcjz77","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210102541"]},{"id":"https://openalex.org/I4210127501","display_name":"National Center of Biomedical Analysis","ror":"https://ror.org/03k3bq214","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mufeng Geng","raw_affiliation_strings":["Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China","Institute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen, China","Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, China","Institute of Medical Technology, Peking University Health Science Center, Peking University, Beijing, China","National Biomedical Imaging Center, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0002-8995-6994","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Institute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, China","institution_ids":["https://openalex.org/I4210102541"]},{"raw_affiliation_string":"Institute of Medical Technology, Peking University Health Science Center, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"National Biomedical Imaging Center, Beijing, China","institution_ids":["https://openalex.org/I4210127501"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062821495","display_name":"Xiangxi Meng","orcid":"https://orcid.org/0000-0002-6590-011X"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I223893228","display_name":"National Medical Products Administration","ror":"https://ror.org/002k3wk88","country_code":"CN","type":"government","lineage":["https://openalex.org/I223893228","https://openalex.org/I4405258220"]},{"id":"https://openalex.org/I4210093964","display_name":"Peking University Cancer Hospital","ror":"https://ror.org/00nyxxr91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093964"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiangxi Meng","raw_affiliation_strings":["Department of Nuclear Medicine, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China","Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Beijing, China"],"raw_orcid":"https://orcid.org/0000-0002-6590-011X","affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210093964"]},{"raw_affiliation_string":"Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Beijing, China","institution_ids":["https://openalex.org/I223893228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015770092","display_name":"Jiangyuan Yu","orcid":"https://orcid.org/0000-0002-6834-3080"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I223893228","display_name":"National Medical Products Administration","ror":"https://ror.org/002k3wk88","country_code":"CN","type":"government","lineage":["https://openalex.org/I223893228","https://openalex.org/I4405258220"]},{"id":"https://openalex.org/I4210093964","display_name":"Peking University Cancer Hospital","ror":"https://ror.org/00nyxxr91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093964"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiangyuan Yu","raw_affiliation_strings":["Department of Nuclear Medicine, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China","Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210093964"]},{"raw_affiliation_string":"Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Beijing, China","institution_ids":["https://openalex.org/I223893228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100380630","display_name":"Lei Zhu","orcid":"https://orcid.org/0000-0003-0506-4268"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210102541","display_name":"Shenzhen Bay Laboratory","ror":"https://ror.org/00sdcjz77","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210102541"]},{"id":"https://openalex.org/I4210127501","display_name":"National Center of Biomedical Analysis","ror":"https://ror.org/03k3bq214","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lei Zhu","raw_affiliation_strings":["Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China","Institute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen, China","Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, China","Institute of Medical Technology, Peking University Health Science Center, Peking University, Beijing, China","National Biomedical Imaging Center, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0003-0506-4268","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Institute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, China","institution_ids":["https://openalex.org/I4210102541"]},{"raw_affiliation_string":"Institute of Medical Technology, Peking University Health Science Center, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"National Biomedical Imaging Center, Beijing, China","institution_ids":["https://openalex.org/I4210127501"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022125103","display_name":"Lujia Jin","orcid":"https://orcid.org/0000-0002-7011-0008"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210102541","display_name":"Shenzhen Bay Laboratory","ror":"https://ror.org/00sdcjz77","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210102541"]},{"id":"https://openalex.org/I4210127501","display_name":"National Center of Biomedical Analysis","ror":"https://ror.org/03k3bq214","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lujia Jin","raw_affiliation_strings":["Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China","Institute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen, China","Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, China","Institute of Medical Technology, Peking University Health Science Center, Peking University, Beijing, China","National Biomedical Imaging Center, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Institute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, China","institution_ids":["https://openalex.org/I4210102541"]},{"raw_affiliation_string":"Institute of Medical Technology, Peking University Health Science Center, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"National Biomedical Imaging Center, Beijing, China","institution_ids":["https://openalex.org/I4210127501"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102841815","display_name":"Zhe Jiang","orcid":"https://orcid.org/0000-0002-0682-4882"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210102541","display_name":"Shenzhen Bay Laboratory","ror":"https://ror.org/00sdcjz77","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210102541"]},{"id":"https://openalex.org/I4210127501","display_name":"National Center of Biomedical Analysis","ror":"https://ror.org/03k3bq214","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhe Jiang","raw_affiliation_strings":["Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China","Institute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen, China","Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, China","Institute of Medical Technology, Peking University Health Science Center, Peking University, Beijing, China","National Biomedical Imaging Center, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0002-0682-4882","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Institute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, China","institution_ids":["https://openalex.org/I4210102541"]},{"raw_affiliation_string":"Institute of Medical Technology, Peking University Health Science Center, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"National Biomedical Imaging Center, Beijing, China","institution_ids":["https://openalex.org/I4210127501"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103275241","display_name":"Bin Qiu","orcid":"https://orcid.org/0000-0001-7278-7701"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210102541","display_name":"Shenzhen Bay Laboratory","ror":"https://ror.org/00sdcjz77","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210102541"]},{"id":"https://openalex.org/I4210127501","display_name":"National Center of Biomedical Analysis","ror":"https://ror.org/03k3bq214","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Qiu","raw_affiliation_strings":["Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China","Institute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen, China","Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, China","Institute of Medical Technology, Peking University Health Science Center, Peking University, Beijing, China","National Biomedical Imaging Center, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Institute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, China","institution_ids":["https://openalex.org/I4210102541"]},{"raw_affiliation_string":"Institute of Medical Technology, Peking University Health Science Center, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"National Biomedical Imaging Center, Beijing, China","institution_ids":["https://openalex.org/I4210127501"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100658729","display_name":"Hui Li","orcid":"https://orcid.org/0000-0003-0610-1083"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I223893228","display_name":"National Medical Products Administration","ror":"https://ror.org/002k3wk88","country_code":"CN","type":"government","lineage":["https://openalex.org/I223893228","https://openalex.org/I4405258220"]},{"id":"https://openalex.org/I4210093964","display_name":"Peking University Cancer Hospital","ror":"https://ror.org/00nyxxr91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093964"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Li","raw_affiliation_strings":["Department of Nuclear Medicine, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China","Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210093964"]},{"raw_affiliation_string":"Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Beijing, China","institution_ids":["https://openalex.org/I223893228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101472610","display_name":"Hanjing Kong","orcid":"https://orcid.org/0000-0003-3329-9646"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hanjing Kong","raw_affiliation_strings":["Central Research Institute, UIH Group, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0003-3329-9646","affiliations":[{"raw_affiliation_string":"Central Research Institute, UIH Group, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023029299","display_name":"Jianmin Yuan","orcid":"https://orcid.org/0000-0001-7223-2757"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jianmin Yuan","raw_affiliation_strings":["Central Research Institute, UIH Group, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Research Institute, UIH Group, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100435639","display_name":"Kun Yang","orcid":"https://orcid.org/0000-0002-6782-6689"},"institutions":[{"id":"https://openalex.org/I43337087","display_name":"Hebei University","ror":"https://ror.org/01p884a79","country_code":"CN","type":"education","lineage":["https://openalex.org/I43337087"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kun Yang","raw_affiliation_strings":["College of Quality and Technical Supervision, Hebei University, Baoding, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Quality and Technical Supervision, Hebei University, Baoding, China","institution_ids":["https://openalex.org/I43337087"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049086157","display_name":"Hongming Shan","orcid":"https://orcid.org/0000-0002-0604-3197"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210164150","display_name":"Shanghai Center for Brain Science and Brain-Inspired Technology","ror":"https://ror.org/0551a0y31","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210164150"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongming Shan","raw_affiliation_strings":["Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China","Shanghai Research Center for Brain Science and Brain-Inspired Technology, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0002-0604-3197","affiliations":[{"raw_affiliation_string":"Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210164150"]},{"raw_affiliation_string":"Shanghai Research Center for Brain Science and Brain-Inspired Technology, Shanghai, China","institution_ids":["https://openalex.org/I4210164150"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101856799","display_name":"Hongbin Han","orcid":"https://orcid.org/0000-0002-6988-4698"},"institutions":[{"id":"https://openalex.org/I4210164150","display_name":"Shanghai Center for Brain Science and Brain-Inspired Technology","ror":"https://ror.org/0551a0y31","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210164150"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongbin Han","raw_affiliation_strings":["Beijing Key Laboratory of Magnetic Resonance Imaging Technology, Beijing, China","Shanghai Research Center for Brain Science and Brain-Inspired Technology, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Magnetic Resonance Imaging Technology, Beijing, China","institution_ids":[]},{"raw_affiliation_string":"Shanghai Research Center for Brain Science and Brain-Inspired Technology, Shanghai, China","institution_ids":["https://openalex.org/I4210164150"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102862758","display_name":"Zhi Yang","orcid":"https://orcid.org/0000-0002-8219-4499"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I223893228","display_name":"National Medical Products Administration","ror":"https://ror.org/002k3wk88","country_code":"CN","type":"government","lineage":["https://openalex.org/I223893228","https://openalex.org/I4405258220"]},{"id":"https://openalex.org/I4210093964","display_name":"Peking University Cancer Hospital","ror":"https://ror.org/00nyxxr91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093964"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhi Yang","raw_affiliation_strings":["Department of Nuclear Medicine, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China","Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210093964"]},{"raw_affiliation_string":"Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Beijing, China","institution_ids":["https://openalex.org/I223893228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018389659","display_name":"Qiushi Ren","orcid":"https://orcid.org/0000-0003-3301-9085"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210102541","display_name":"Shenzhen Bay Laboratory","ror":"https://ror.org/00sdcjz77","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210102541"]},{"id":"https://openalex.org/I4210127501","display_name":"National Center of Biomedical Analysis","ror":"https://ror.org/03k3bq214","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiushi Ren","raw_affiliation_strings":["Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China","Institute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen, China","Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, China","Institute of Medical Technology, Peking University Health Science Center, Peking University, Beijing, China","National Biomedical Imaging Center, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Institute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, China","institution_ids":["https://openalex.org/I4210102541"]},{"raw_affiliation_string":"Institute of Medical Technology, Peking University Health Science Center, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"National Biomedical Imaging Center, Beijing, China","institution_ids":["https://openalex.org/I4210127501"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082320568","display_name":"Yanye Lu","orcid":"https://orcid.org/0000-0002-3063-8051"},"institutions":[{"id":"https://openalex.org/I4210164150","display_name":"Shanghai Center for Brain Science and Brain-Inspired Technology","ror":"https://ror.org/0551a0y31","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210164150"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanye Lu","raw_affiliation_strings":["Beijing Key Laboratory of Magnetic Resonance Imaging Technology, Beijing, China","Shanghai Research Center for Brain Science and Brain-Inspired Technology, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0002-3063-8051","affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Magnetic Resonance Imaging Technology, Beijing, China","institution_ids":[]},{"raw_affiliation_string":"Shanghai Research Center for Brain Science and Brain-Inspired Technology, Shanghai, China","institution_ids":["https://openalex.org/I4210164150"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2045,"currency":"USD","value_usd":2045},"apc_paid":null,"fwci":10.5703,"has_fulltext":false,"cited_by_count":182,"citation_normalized_percentile":{"value":0.99095465,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"41","issue":"2","first_page":"407","last_page":"419"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10688","display_name":"Image and Signal Denoising Methods","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10688","display_name":"Image and Signal Denoising Methods","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9937999844551086,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9860000014305115,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7624190449714661},{"id":"https://openalex.org/keywords/noise-reduction","display_name":"Noise reduction","score":0.738200306892395},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6867351531982422},{"id":"https://openalex.org/keywords/generalization","display_name":"Generalization","score":0.58690345287323},{"id":"https://openalex.org/keywords/medical-imaging","display_name":"Medical imaging","score":0.5825930833816528},{"id":"https://openalex.org/keywords/noise","display_name":"Noise (video)","score":0.5480048060417175},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.52765953540802},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.5107231140136719},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.47642478346824646},{"id":"https://openalex.org/keywords/video-denoising","display_name":"Video denoising","score":0.4654539227485657},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.44177931547164917},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.39901095628738403},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.33883175253868103},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.10330396890640259},{"id":"https://openalex.org/keywords/video-processing","display_name":"Video processing","score":0.10147666931152344}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7624190449714661},{"id":"https://openalex.org/C163294075","wikidata":"https://www.wikidata.org/wiki/Q581861","display_name":"Noise reduction","level":2,"score":0.738200306892395},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6867351531982422},{"id":"https://openalex.org/C177148314","wikidata":"https://www.wikidata.org/wiki/Q170084","display_name":"Generalization","level":2,"score":0.58690345287323},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.5825930833816528},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.5480048060417175},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.52765953540802},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.5107231140136719},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.47642478346824646},{"id":"https://openalex.org/C30814859","wikidata":"https://www.wikidata.org/wiki/Q4119603","display_name":"Video denoising","level":5,"score":0.4654539227485657},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.44177931547164917},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.39901095628738403},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.33883175253868103},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.10330396890640259},{"id":"https://openalex.org/C65483669","wikidata":"https://www.wikidata.org/wiki/Q3536669","display_name":"Video processing","level":2,"score":0.10147666931152344},{"id":"https://openalex.org/C23431618","wikidata":"https://www.wikidata.org/wiki/Q1404672","display_name":"Multiview Video Coding","level":4,"score":0.0},{"id":"https://openalex.org/C202474056","wikidata":"https://www.wikidata.org/wiki/Q1931635","display_name":"Video tracking","level":3,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tmi.2021.3113365","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2021.3113365","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:34529565","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34529565","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1981558879","display_name":null,"funder_award_id":"Z210008","funder_id":"https://openalex.org/F4320322919","funder_display_name":"Natural Science Foundation of Beijing Municipality"},{"id":"https://openalex.org/G2954827595","display_name":null,"funder_award_id":"H2019201378","funder_id":"https://openalex.org/F4320322163","funder_display_name":"Natural Science Foundation of Hebei Province"}],"funders":[{"id":"https://openalex.org/F4320322163","display_name":"Natural Science Foundation of Hebei Province","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322919","display_name":"Natural Science Foundation of Beijing Municipality","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":61,"referenced_works":["https://openalex.org/W1836465849","https://openalex.org/W1901129140","https://openalex.org/W2041114617","https://openalex.org/W2073660032","https://openalex.org/W2078762618","https://openalex.org/W2094602468","https://openalex.org/W2110442226","https://openalex.org/W2114770744","https://openalex.org/W2133665775","https://openalex.org/W2146444218","https://openalex.org/W2163054987","https://openalex.org/W2314720829","https://openalex.org/W2570202822","https://openalex.org/W2584483805","https://openalex.org/W2729145866","https://openalex.org/W2743780012","https://openalex.org/W2748739903","https://openalex.org/W2753305843","https://openalex.org/W2775516437","https://openalex.org/W2777741489","https://openalex.org/W2780544323","https://openalex.org/W2787564202","https://openalex.org/W2789588857","https://openalex.org/W2791655542","https://openalex.org/W2799192307","https://openalex.org/W2801585709","https://openalex.org/W2902378515","https://openalex.org/W2948149465","https://openalex.org/W2958646971","https://openalex.org/W2963073614","https://openalex.org/W2963470893","https://openalex.org/W2964101377","https://openalex.org/W2964296115","https://openalex.org/W2964308363","https://openalex.org/W2971983564","https://openalex.org/W2975696535","https://openalex.org/W2996759893","https://openalex.org/W3002137088","https://openalex.org/W3034448817","https://openalex.org/W3037582100","https://openalex.org/W3041500444","https://openalex.org/W3080481874","https://openalex.org/W3083061165","https://openalex.org/W3089335504","https://openalex.org/W3092661142","https://openalex.org/W3099147628","https://openalex.org/W3103261259","https://openalex.org/W3105403262","https://openalex.org/W3110520628","https://openalex.org/W3126820293","https://openalex.org/W3145248306","https://openalex.org/W3157423176","https://openalex.org/W4242059867","https://openalex.org/W4250955649","https://openalex.org/W4295312788","https://openalex.org/W4297813639","https://openalex.org/W6638667902","https://openalex.org/W6639824700","https://openalex.org/W6698971750","https://openalex.org/W6734524426","https://openalex.org/W6766978945"],"related_works":["https://openalex.org/W2387796150","https://openalex.org/W1987356308","https://openalex.org/W3119800349","https://openalex.org/W4385272703","https://openalex.org/W2513570774","https://openalex.org/W2139368882","https://openalex.org/W4214691059","https://openalex.org/W4287907666","https://openalex.org/W2792992868","https://openalex.org/W2997240037"],"abstract_inverted_index":{"Medical":[0],"imaging":[1,16,108],"denoising":[2,17,66,123,156],"faces":[3],"great":[4,9],"challenges,":[5],"yet":[6,34,147],"is":[7,73,76,168],"in":[8,18,43,125,164],"demand.":[10],"With":[11],"its":[12],"distinctive":[13],"characteristics,":[14],"medical":[15,64,107,154],"the":[19,37,53,59,70,95,134,165],"image":[20,60,65,155],"domain":[21],"requires":[22],"innovative":[23],"deep":[24,46],"learning":[25,40,47],"strategies.":[26],"In":[27],"this":[28,119,145],"study,":[29],"we":[30],"propose":[31],"a":[32,79,137,161],"simple":[33,146],"effective":[35,148],"strategy,":[36,42],"content-noise":[38],"complementary":[39],"(CNCL)":[41],"which":[44,158],"two":[45],"predictors":[48],"are":[49,92],"used":[50],"to":[51],"learn":[52],"respective":[54],"content":[55],"and":[56,75,90,113,130,133],"noise":[57],"of":[58,99,127],"dataset":[61],"complementarily.":[62],"A":[63],"pipeline":[67],"based":[68],"on":[69,106],"CNCL":[71],"strategy":[72,120,135,149],"presented,":[74],"implemented":[77,101],"as":[78,94],"generative":[80],"adversarial":[81],"network,":[82],"where":[83],"various":[84],"representative":[85],"networks":[86],"(including":[87],"U-Net,":[88],"DnCNN,":[89],"SRDenseNet)":[91],"investigated":[93],"predictors.":[96],"The":[97,115],"performance":[98],"these":[100],"models":[102],"has":[103],"been":[104],"validated":[105],"datasets":[109],"including":[110],"CT,":[111],"MR,":[112],"PET.":[114],"results":[116],"show":[117],"that":[118,144],"outperforms":[121],"state-of-the-art":[122],"algorithms":[124],"terms":[126],"visual":[128],"quality":[129],"quantitative":[131],"metrics,":[132],"demonstrates":[136,150],"robust":[138],"generalization":[139],"capability.":[140],"These":[141],"findings":[142],"validate":[143],"promising":[151],"potential":[152],"for":[153],"tasks,":[157],"could":[159],"exert":[160],"clinical":[162],"impact":[163],"future.":[166],"Code":[167],"available":[169],"at:":[170],"https://github.com/gengmufeng/CNCL-denoising.":[171]},"counts_by_year":[{"year":2026,"cited_by_count":17},{"year":2025,"cited_by_count":51},{"year":2024,"cited_by_count":58},{"year":2023,"cited_by_count":42},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":2}],"updated_date":"2026-08-28T12:50:07.497085","created_date":"2025-10-10T00:00:00"}