{"id":"https://openalex.org/W3161401602","doi":"https://doi.org/10.1109/tmi.2021.3080991","title":"Two-Stream Compare and Contrast Network for Vertebral Compression Fracture Diagnosis","display_name":"Two-Stream Compare and Contrast Network for Vertebral Compression Fracture Diagnosis","publication_year":2021,"publication_date":"2021-05-17","ids":{"openalex":"https://openalex.org/W3161401602","doi":"https://doi.org/10.1109/tmi.2021.3080991","mag":"3161401602","pmid":"https://pubmed.ncbi.nlm.nih.gov/33999815"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2021.3080991","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2021.3080991","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108280801","display_name":"Shixiang Feng","orcid":"https://orcid.org/0009-0000-1831-0304"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210099312","display_name":"Shandong Jiaotong University","ror":"https://ror.org/01848hk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210099312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shixiang Feng","raw_affiliation_strings":["Cooperative Medianet Innovation Center, Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cooperative Medianet Innovation Center, Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210099312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100623317","display_name":"Beibei Liu","orcid":"https://orcid.org/0000-0003-3788-018X"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210144482","display_name":"Shanghai Sixth People's Hospital","ror":"https://ror.org/049zrh188","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210144482"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Beibei Liu","raw_affiliation_strings":["Institute of Diagnostic and Interventional Radiology, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China","Institute of Diagnostic and Interventional Radiology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Diagnostic and Interventional Radiology, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I4210144482"]},{"raw_affiliation_string":"Institute of Diagnostic and Interventional Radiology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210144482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100342828","display_name":"Ya Zhang","orcid":"https://orcid.org/0000-0002-5390-9053"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210099312","display_name":"Shandong Jiaotong University","ror":"https://ror.org/01848hk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210099312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ya Zhang","raw_affiliation_strings":["Cooperative Medianet Innovation Center, Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0002-5390-9053","affiliations":[{"raw_affiliation_string":"Cooperative Medianet Innovation Center, Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210099312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100452809","display_name":"Xiaoyun Zhang","orcid":"https://orcid.org/0000-0001-7680-4062"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210099312","display_name":"Shandong Jiaotong University","ror":"https://ror.org/01848hk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210099312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoyun Zhang","raw_affiliation_strings":["Cooperative Medianet Innovation Center, Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0001-7680-4062","affiliations":[{"raw_affiliation_string":"Cooperative Medianet Innovation Center, Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210099312"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100721621","display_name":"Yuehua Li","orcid":"https://orcid.org/0000-0001-8028-248X"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210144482","display_name":"Shanghai Sixth People's Hospital","ror":"https://ror.org/049zrh188","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210144482"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuehua Li","raw_affiliation_strings":["Institute of Diagnostic and Interventional Radiology, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China","Institute of Diagnostic and Interventional Radiology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Diagnostic and Interventional Radiology, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I4210144482"]},{"raw_affiliation_string":"Institute of Diagnostic and Interventional Radiology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210144482"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7982,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.66078439,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"40","issue":"9","first_page":"2496","last_page":"2506"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14510","display_name":"Medical Imaging and Analysis","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T14510","display_name":"Medical Imaging and Analysis","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12209","display_name":"Bone and Joint Diseases","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11293","display_name":"Orthopedic Infections and Treatments","score":0.9860000014305115,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7398222088813782},{"id":"https://openalex.org/keywords/contrast","display_name":"Contrast (vision)","score":0.6221432685852051},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.598040759563446},{"id":"https://openalex.org/keywords/class","display_name":"Class (philosophy)","score":0.571048378944397},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5062648057937622},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.4517377018928528},{"id":"https://openalex.org/keywords/vertebral-compression-fracture","display_name":"Vertebral compression fracture","score":0.43271711468696594},{"id":"https://openalex.org/keywords/compression","display_name":"Compression (physics)","score":0.39455652236938477},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.23507782816886902}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7398222088813782},{"id":"https://openalex.org/C2776502983","wikidata":"https://www.wikidata.org/wiki/Q690182","display_name":"Contrast (vision)","level":2,"score":0.6221432685852051},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.598040759563446},{"id":"https://openalex.org/C2777212361","wikidata":"https://www.wikidata.org/wiki/Q5127848","display_name":"Class (philosophy)","level":2,"score":0.571048378944397},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5062648057937622},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.4517377018928528},{"id":"https://openalex.org/C2779386548","wikidata":"https://www.wikidata.org/wiki/Q2289642","display_name":"Vertebral compression fracture","level":3,"score":0.43271711468696594},{"id":"https://openalex.org/C180016635","wikidata":"https://www.wikidata.org/wiki/Q2712821","display_name":"Compression (physics)","level":2,"score":0.39455652236938477},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.23507782816886902},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013131","descriptor_name":"Spine","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D013131","descriptor_name":"Spine","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D013131","descriptor_name":"Spine","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D016103","descriptor_name":"Spinal Fractures","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D016103","descriptor_name":"Spinal Fractures","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D016103","descriptor_name":"Spinal Fractures","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D050815","descriptor_name":"Fractures, Compression","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D050815","descriptor_name":"Fractures, Compression","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D050815","descriptor_name":"Fractures, Compression","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tmi.2021.3080991","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2021.3080991","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:33999815","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33999815","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5299999713897705,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G1866817718","display_name":null,"funder_award_id":"2018-RGZN-02046","funder_id":"https://openalex.org/F4320325413","funder_display_name":"Shanghai Municipal Commission of Economy and Informatization"},{"id":"https://openalex.org/G2603165212","display_name":"\u9762\u5411\u5206\u5e03\u5f0f\u6700\u4f18\u5316\u95ee\u9898\u7684\u673a\u5668\u5b66\u4e60\u6c42\u89e3\u7b97\u6cd5\u7814\u7a76","funder_award_id":"12071145","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7814127966","display_name":null,"funder_award_id":"18DZ2270700","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321885","display_name":"Science and Technology Commission of Shanghai Municipality","ror":"https://ror.org/03kt66j61"},{"id":"https://openalex.org/F4320325413","display_name":"Shanghai Municipal Commission of Economy and Informatization","ror":"https://ror.org/04166ws88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W1510681258","https://openalex.org/W1686810756","https://openalex.org/W1995890416","https://openalex.org/W2003106423","https://openalex.org/W2030002027","https://openalex.org/W2096733369","https://openalex.org/W2118978333","https://openalex.org/W2187089797","https://openalex.org/W2194775991","https://openalex.org/W2279560745","https://openalex.org/W2295109081","https://openalex.org/W2394599079","https://openalex.org/W2440599146","https://openalex.org/W2508374236","https://openalex.org/W2592719727","https://openalex.org/W2601810159","https://openalex.org/W2752782242","https://openalex.org/W2783715470","https://openalex.org/W2784790358","https://openalex.org/W2795282075","https://openalex.org/W2798381792","https://openalex.org/W2798869704","https://openalex.org/W2800043213","https://openalex.org/W2883888092","https://openalex.org/W2888860107","https://openalex.org/W2890599568","https://openalex.org/W2891951760","https://openalex.org/W2901559346","https://openalex.org/W2914959431","https://openalex.org/W2940562104","https://openalex.org/W2957485116","https://openalex.org/W2962858109","https://openalex.org/W2963371670","https://openalex.org/W2963404649","https://openalex.org/W2963420686","https://openalex.org/W2963691377","https://openalex.org/W2963967185","https://openalex.org/W2970941190","https://openalex.org/W2979338452","https://openalex.org/W2979777575","https://openalex.org/W2980218604","https://openalex.org/W3034711780","https://openalex.org/W3035131301","https://openalex.org/W3097781047","https://openalex.org/W3099206234","https://openalex.org/W4289454094","https://openalex.org/W6637373629","https://openalex.org/W6734614501","https://openalex.org/W6747746473","https://openalex.org/W6750523955","https://openalex.org/W6764733053","https://openalex.org/W6779091605"],"related_works":["https://openalex.org/W2182101718","https://openalex.org/W1997445737","https://openalex.org/W2291795816","https://openalex.org/W2395822617","https://openalex.org/W2611802601","https://openalex.org/W2892248074","https://openalex.org/W1985690632","https://openalex.org/W3155494986","https://openalex.org/W2045753233","https://openalex.org/W4390971595"],"abstract_inverted_index":{"Differentiating":[0],"Vertebral":[1],"Compression":[2],"Fractures":[3],"(VCFs)":[4],"associated":[5],"with":[6],"trauma":[7],"and":[8,41,68,74,80,89,110,133,138,144,148,183,188,192],"osteoporosis":[9],"(benign":[10],"VCFs)":[11,19],"or":[12,47],"those":[13],"caused":[14],"by":[15,85],"metastatic":[16],"cancer":[17],"(malignant":[18],"is":[20,31,96,173],"critically":[21],"important":[22],"for":[23,114,153],"treatment":[24],"decisions.":[25],"So":[26],"far,":[27],"automatic":[28],"VCFs":[29,40,56,72,115,130,181],"diagnosis":[30,57],"solved":[32],"in":[33],"a":[34,59,106,123,139,162,176],"two-step":[35],"manner,":[36],"i.e.,":[37,63],"first":[38],"identify":[39,129],"then":[42],"classify":[43],"them":[44],"into":[45],"benign":[46,66],"malignant.":[48],"In":[49],"this":[50],"paper,":[51],"we":[52,104],"explore":[53],"to":[54,128,150],"model":[55],"as":[58],"three-class":[60],"classification":[61,75,140],"problem,":[62],"normal":[64],"vertebrae,":[65,137],"VCFs,":[67],"malignant":[69],"VCFs.":[70],"However,":[71],"recognition":[73,124],"require":[76],"very":[77],"different":[78],"features,":[79],"both":[81],"tasks":[82],"are":[83,159],"characterized":[84],"high":[86,90],"intra-class":[87,147],"variation":[88],"inter-class":[91,149],"similarity.":[92],"Moreover,":[93],"the":[94,101,185],"dataset":[95,177],"extremely":[97],"class-imbalanced.":[98],"To":[99],"address":[100],"above":[102],"challenges,":[103],"propose":[105],"novel":[107],"Two-Stream":[108],"Compare":[109],"Contrast":[111],"Network":[112],"(TSCCN)":[113],"diagnosis.":[116],"This":[117],"network":[118],"consists":[119],"of":[120,179,190],"two":[121,157],"streams,":[122],"stream":[125,141],"which":[126,142,167],"learns":[127],"through":[131],"comparing":[132],"contrasting":[134],"between":[135,146],"adjacent":[136],"compares":[143],"contrasts":[145],"learn":[151],"features":[152],"fine-grained":[154],"classification.":[155],"The":[156],"streams":[158],"integrated":[160],"via":[161],"learnable":[163],"weight":[164],"control":[165],"module":[166],"adaptively":[168],"sets":[169],"their":[170],"contribution.":[171],"TSCCN":[172],"evaluated":[174],"on":[175],"consisting":[178],"239":[180],"patients":[182],"achieves":[184],"average":[186],"sensitivity":[187],"specificity":[189],"92.56%":[191],"96.29%,":[193],"respectively.":[194]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1}],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}