{"id":"https://openalex.org/W3092991072","doi":"https://doi.org/10.1109/tmi.2020.3031289","title":"Spherical-Patches Extraction for Deep-Learning-Based Critical Points Detection in 3D Neuron Microscopy Images","display_name":"Spherical-Patches Extraction for Deep-Learning-Based Critical Points Detection in 3D Neuron Microscopy Images","publication_year":2020,"publication_date":"2020-10-15","ids":{"openalex":"https://openalex.org/W3092991072","doi":"https://doi.org/10.1109/tmi.2020.3031289","mag":"3092991072","pmid":"https://pubmed.ncbi.nlm.nih.gov/33055023"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2020.3031289","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2020.3031289","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011466255","display_name":"Weixun Chen","orcid":"https://orcid.org/0000-0002-1583-5807"},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Weixun Chen","raw_affiliation_strings":["College of Electrical and Information Engineering, Hunan University, Changsha, China","National Engineering Laboratory for Robot Vision Perception and Control, Hunan University, Changsha, China"],"affiliations":[{"raw_affiliation_string":"College of Electrical and Information Engineering, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"National Engineering Laboratory for Robot Vision Perception and Control, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100343854","display_name":"Min Liu","orcid":"https://orcid.org/0000-0001-6406-4896"},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Liu","raw_affiliation_strings":["College of Electrical and Information Engineering, Hunan University, Changsha, China","National Engineering Laboratory for Robot Vision Perception and Control, Hunan University, Changsha, China"],"affiliations":[{"raw_affiliation_string":"College of Electrical and Information Engineering, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"National Engineering Laboratory for Robot Vision Perception and Control, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101890179","display_name":"Qi Zhan","orcid":"https://orcid.org/0009-0000-4544-3903"},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qi Zhan","raw_affiliation_strings":["College of Electrical and Information Engineering, Hunan University, Changsha, China","National Engineering Laboratory for Robot Vision Perception and Control, Hunan University, Changsha, China"],"affiliations":[{"raw_affiliation_string":"College of Electrical and Information Engineering, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"National Engineering Laboratory for Robot Vision Perception and Control, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011942105","display_name":"Yinghui Tan","orcid":"https://orcid.org/0000-0002-3617-8252"},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yinghui Tan","raw_affiliation_strings":["College of Electrical and Information Engineering, Hunan University, Changsha, China","National Engineering Laboratory for Robot Vision Perception and Control, Hunan University, Changsha, China"],"affiliations":[{"raw_affiliation_string":"College of Electrical and Information Engineering, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"National Engineering Laboratory for Robot Vision Perception and Control, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023548565","display_name":"Erik Meijering","orcid":"https://orcid.org/0000-0001-8015-8358"},"institutions":[{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Erik Meijering","raw_affiliation_strings":["Graduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW, Australia","School of Computer Science and Engineering, University of New South Wales, Sydney, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"Graduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW, Australia","institution_ids":["https://openalex.org/I31746571"]},{"raw_affiliation_string":"School of Computer Science and Engineering, University of New South Wales, Sydney, NSW, Australia","institution_ids":["https://openalex.org/I31746571"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069090518","display_name":"Miroslav Radojevi\u0107","orcid":"https://orcid.org/0000-0003-4480-1232"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Miroslav Radojevic","raw_affiliation_strings":["Nuctech Netherlands, AP Rotterdam, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Nuctech Netherlands, AP Rotterdam, The Netherlands","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025640070","display_name":"Yaonan Wang","orcid":"https://orcid.org/0000-0002-0519-6458"},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaonan Wang","raw_affiliation_strings":["College of Electrical and Information Engineering, Hunan University, Changsha, China","National Engineering Laboratory for Robot Vision Perception and Control, Hunan University, Changsha, China"],"affiliations":[{"raw_affiliation_string":"College of Electrical and Information Engineering, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"National Engineering Laboratory for Robot Vision Perception and Control, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5011466255"],"corresponding_institution_ids":["https://openalex.org/I16609230"],"apc_list":null,"apc_paid":null,"fwci":3.7396,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.93661171,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"40","issue":"2","first_page":"527","last_page":"538"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9901000261306763,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6164076328277588},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5609158277511597},{"id":"https://openalex.org/keywords/point","display_name":"Point (geometry)","score":0.49137082695961},{"id":"https://openalex.org/keywords/critical-point","display_name":"Critical point (mathematics)","score":0.47663414478302},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.46144384145736694},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.45843061804771423},{"id":"https://openalex.org/keywords/azimuth","display_name":"Azimuth","score":0.42196419835090637},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.4055938124656677},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.33125409483909607},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2662341296672821},{"id":"https://openalex.org/keywords/geometry","display_name":"Geometry","score":0.25733691453933716}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6164076328277588},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5609158277511597},{"id":"https://openalex.org/C28719098","wikidata":"https://www.wikidata.org/wiki/Q44946","display_name":"Point (geometry)","level":2,"score":0.49137082695961},{"id":"https://openalex.org/C196298200","wikidata":"https://www.wikidata.org/wiki/Q577705","display_name":"Critical point (mathematics)","level":2,"score":0.47663414478302},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.46144384145736694},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.45843061804771423},{"id":"https://openalex.org/C159737794","wikidata":"https://www.wikidata.org/wiki/Q124274","display_name":"Azimuth","level":2,"score":0.42196419835090637},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4055938124656677},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.33125409483909607},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2662341296672821},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.25733691453933716}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tmi.2020.3031289","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2020.3031289","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:33055023","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33055023","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1259047040","display_name":null,"funder_award_id":"62073126","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3261378140","display_name":null,"funder_award_id":"2020JJ2008","funder_id":"https://openalex.org/F4320322843","funder_display_name":"Natural Science Foundation of\u00a0Hunan Province"},{"id":"https://openalex.org/G7766621390","display_name":null,"funder_award_id":"CX20190301","funder_id":"https://openalex.org/F4320326217","funder_display_name":"Hunan Provincial Innovation Foundation for Postgraduate"},{"id":"https://openalex.org/G8810697831","display_name":null,"funder_award_id":"61771189","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322843","display_name":"Natural Science Foundation of\u00a0Hunan Province","ror":null},{"id":"https://openalex.org/F4320326217","display_name":"Hunan Provincial Innovation Foundation for Postgraduate","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W46659105","https://openalex.org/W1508135620","https://openalex.org/W1522301498","https://openalex.org/W1563397979","https://openalex.org/W1644641054","https://openalex.org/W1832101600","https://openalex.org/W1871050032","https://openalex.org/W1901129140","https://openalex.org/W1968901737","https://openalex.org/W1989396876","https://openalex.org/W1992621211","https://openalex.org/W2001658278","https://openalex.org/W2014252132","https://openalex.org/W2018227909","https://openalex.org/W2028714055","https://openalex.org/W2124257654","https://openalex.org/W2156012604","https://openalex.org/W2156114286","https://openalex.org/W2168393756","https://openalex.org/W2202170526","https://openalex.org/W2209890352","https://openalex.org/W2334170987","https://openalex.org/W2345173121","https://openalex.org/W2404192493","https://openalex.org/W2544277621","https://openalex.org/W2571219130","https://openalex.org/W2594660495","https://openalex.org/W2600862990","https://openalex.org/W2750661942","https://openalex.org/W2752782242","https://openalex.org/W2798122215","https://openalex.org/W2903771707","https://openalex.org/W2910669864","https://openalex.org/W2912059704","https://openalex.org/W2952846208","https://openalex.org/W2962682465","https://openalex.org/W2962731536","https://openalex.org/W2963163009","https://openalex.org/W2963420686","https://openalex.org/W2963637380","https://openalex.org/W2964121744","https://openalex.org/W2966593583","https://openalex.org/W2979910668","https://openalex.org/W2982083293","https://openalex.org/W3022194838","https://openalex.org/W6602002561","https://openalex.org/W6631190155","https://openalex.org/W6639824700","https://openalex.org/W6750469568"],"related_works":["https://openalex.org/W3006474185","https://openalex.org/W2483195039","https://openalex.org/W2611761074","https://openalex.org/W2048211457","https://openalex.org/W2281797687","https://openalex.org/W2358411735","https://openalex.org/W2107024632","https://openalex.org/W2358598243","https://openalex.org/W2331534598","https://openalex.org/W2313632216"],"abstract_inverted_index":{"Digital":[0],"reconstruction":[1,13,210],"of":[2,18,49,69,96,118,137,180,215],"neuronal":[3],"structures":[4],"is":[5,122,159],"very":[6],"important":[7],"to":[8,63,107,134,161,221],"neuroscience":[9],"research.":[10],"Many":[11],"existing":[12],"algorithms":[14],"require":[15],"a":[16,41,61,79,85,94,102,116,145,233],"set":[17,95],"good":[19,34,223],"seed":[20,38,224],"points.":[21,39],"3D":[22,70],"neuron":[23,74,209,218,227,238],"critical":[24,50,71,104,175,201,206,219,239],"points,":[25,32],"including":[26],"terminations,":[27],"branch":[28,184],"points":[29,51,72,202,207,220,225,240],"and":[30,84,140,171],"cross-over":[31,186],"are":[33],"candidates":[35],"for":[36,226,237],"such":[37],"However,":[40],"method":[42,62,83,197],"that":[43,194],"can":[44],"simultaneously":[45,64],"detect":[46,65],"all":[47,66],"types":[48,68],"has":[52,243],"barely":[53],"been":[54,244],"explored.":[55],"In":[56],"this":[57,248],"work,":[58],"we":[59,230],"present":[60],"3":[67],"in":[73,149],"microscopy":[75],"images,":[76],"based":[77,208],"on":[78],"spherical-patches":[80],"extraction":[81],"(SPE)":[82],"2D":[86,119,129,146],"multi-stream":[87,147],"convolutional":[88],"neural":[89],"network":[90],"(CNN).":[91],"SPE":[92],"uses":[93],"concentric":[97],"spherical":[98,120,155,169],"surfaces":[99,127],"centered":[100],"at":[101],"given":[103,174],"point":[105,176,187],"candidate":[106,177],"extract":[108],"intensity":[109,164],"distribution":[110,165],"features":[111,166],"around":[112],"the":[113,126,135,138,141,163,173,195,213,216],"point.":[114,190],"Then,":[115],"group":[117],"patches":[121,132,170],"generated":[123],"by":[124],"projecting":[125],"into":[128,178],"rectangular":[130],"image":[131],"according":[133],"orders":[136],"azimuth":[139],"polar":[142],"angles.":[143],"Finally,":[144],"CNN,":[148],"which":[150,242],"each":[151],"stream":[152],"receives":[153],"one":[154,179],"patch":[156],"as":[157],"input,":[158],"designed":[160],"learn":[162],"from":[167],"those":[168],"classify":[172],"four":[181],"classes:":[182],"termination,":[183],"point,":[185],"or":[188],"non-critical":[189],"Experimental":[191],"results":[192,211],"confirm":[193],"proposed":[196],"outperforms":[198],"other":[199],"state-of-the-art":[200],"detection":[203],"methods.":[204],"The":[205],"demonstrate":[212],"potential":[214],"detected":[217],"be":[222],"reconstruction.":[228],"Additionally,":[229],"have":[231],"established":[232],"public":[234],"dataset":[235],"dedicated":[236],"detection,":[241],"released":[245],"along":[246],"with":[247],"article.":[249]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":9}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
