{"id":"https://openalex.org/W3008512199","doi":"https://doi.org/10.1109/tmi.2020.2975853","title":"Multi-View Spatial Aggregation Framework for Joint Localization and Segmentation of Organs at Risk in Head and Neck CT Images","display_name":"Multi-View Spatial Aggregation Framework for Joint Localization and Segmentation of Organs at Risk in Head and Neck CT Images","publication_year":2020,"publication_date":"2020-02-25","ids":{"openalex":"https://openalex.org/W3008512199","doi":"https://doi.org/10.1109/tmi.2020.2975853","mag":"3008512199","pmid":"https://pubmed.ncbi.nlm.nih.gov/32091997"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2020.2975853","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2020.2975853","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048749701","display_name":"Shujun Liang","orcid":"https://orcid.org/0000-0002-9567-0407"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN","US"],"is_corresponding":true,"raw_author_name":"Shujun Liang","raw_affiliation_strings":["Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, China","School of Biomedical Engineering, Southern Medical University, Guangzhou, China","University of North Carolina at Chapel Hill, Chapel Hill, USA"],"raw_orcid":"https://orcid.org/0000-0002-9567-0407","affiliations":[{"raw_affiliation_string":"Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"School of Biomedical Engineering, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"University of North Carolina at Chapel Hill, Chapel Hill, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075744244","display_name":"Kim\u2010Han Thung","orcid":"https://orcid.org/0000-0003-1379-2185"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kim-Han Thung","raw_affiliation_strings":["University of North Carolina at Chapel Hill, Chapel Hill, USA"],"raw_orcid":"https://orcid.org/0000-0003-1379-2185","affiliations":[{"raw_affiliation_string":"University of North Carolina at Chapel Hill, Chapel Hill, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064564558","display_name":"Dong Nie","orcid":"https://orcid.org/0000-0003-0385-8988"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dong Nie","raw_affiliation_strings":["Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, USA"],"raw_orcid":"https://orcid.org/0000-0003-0385-8988","affiliations":[{"raw_affiliation_string":"Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100433430","display_name":"Yu Zhang","orcid":"https://orcid.org/0000-0001-8456-7335"},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Zhang","raw_affiliation_strings":["Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, China","School of Biomedical Engineering, Southern Medical University, Guangzhou, China"],"raw_orcid":"https://orcid.org/0000-0001-8456-7335","affiliations":[{"raw_affiliation_string":"Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"School of Biomedical Engineering, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000937401","display_name":"Dinggang Shen","orcid":"https://orcid.org/0000-0002-7934-5698"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR","US"],"is_corresponding":false,"raw_author_name":"Dinggang Shen","raw_affiliation_strings":["Korea University, Seoul, South Korea","University of North Carolina at Chapel Hill, Chapel Hill, USA"],"raw_orcid":"https://orcid.org/0000-0002-7934-5698","affiliations":[{"raw_affiliation_string":"Korea University, Seoul, South Korea","institution_ids":["https://openalex.org/I197347611"]},{"raw_affiliation_string":"University of North Carolina at Chapel Hill, Chapel Hill, USA","institution_ids":["https://openalex.org/I114027177"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5048749701"],"corresponding_institution_ids":["https://openalex.org/I114027177","https://openalex.org/I58200834"],"apc_list":null,"apc_paid":null,"fwci":8.7456,"has_fulltext":false,"cited_by_count":48,"citation_normalized_percentile":{"value":0.98311911,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"39","issue":"9","first_page":"2794","last_page":"2805"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10036","display_name":"Advanced Neural Network Applications","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.8237338066101074},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7190531492233276},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7146284580230713},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5452147722244263},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.5280828475952148},{"id":"https://openalex.org/keywords/region-of-interest","display_name":"Region of interest","score":0.47553086280822754},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.4462060332298279},{"id":"https://openalex.org/keywords/sagittal-plane","display_name":"Sagittal plane","score":0.4400434195995331},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4351409673690796},{"id":"https://openalex.org/keywords/representation","display_name":"Representation (politics)","score":0.43295615911483765},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.09969276189804077}],"concepts":[{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.8237338066101074},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7190531492233276},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7146284580230713},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5452147722244263},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.5280828475952148},{"id":"https://openalex.org/C19609008","wikidata":"https://www.wikidata.org/wiki/Q2138203","display_name":"Region of interest","level":2,"score":0.47553086280822754},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.4462060332298279},{"id":"https://openalex.org/C178910020","wikidata":"https://www.wikidata.org/wiki/Q2211994","display_name":"Sagittal plane","level":2,"score":0.4400434195995331},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4351409673690796},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.43295615911483765},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.09969276189804077},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058958","descriptor_name":"Organs at Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058958","descriptor_name":"Organs at Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058958","descriptor_name":"Organs at Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tmi.2020.2975853","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2020.2975853","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:32091997","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32091997","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4617950618","display_name":null,"funder_award_id":"61971213","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7462080110","display_name":null,"funder_award_id":"61671230","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W114517082","https://openalex.org/W639708223","https://openalex.org/W1533861849","https://openalex.org/W1871050032","https://openalex.org/W1903029394","https://openalex.org/W1987869189","https://openalex.org/W2074271088","https://openalex.org/W2107595635","https://openalex.org/W2121403362","https://openalex.org/W2123312079","https://openalex.org/W2129259959","https://openalex.org/W2146488048","https://openalex.org/W2155893237","https://openalex.org/W2159676301","https://openalex.org/W2169631870","https://openalex.org/W2194775991","https://openalex.org/W2519106229","https://openalex.org/W2533800772","https://openalex.org/W2560725027","https://openalex.org/W2592929672","https://openalex.org/W2593013519","https://openalex.org/W2766518925","https://openalex.org/W2792155504","https://openalex.org/W2888667538","https://openalex.org/W2896797790","https://openalex.org/W2900677237","https://openalex.org/W2962984928","https://openalex.org/W2963150697","https://openalex.org/W2978708129","https://openalex.org/W4206348406","https://openalex.org/W6631943919","https://openalex.org/W6744318051","https://openalex.org/W6754644398"],"related_works":["https://openalex.org/W2053950117","https://openalex.org/W4293226380","https://openalex.org/W3029575091","https://openalex.org/W4386008762","https://openalex.org/W2536657158","https://openalex.org/W2085797056","https://openalex.org/W2027366028","https://openalex.org/W2329643775","https://openalex.org/W3145923612","https://openalex.org/W1522196789"],"abstract_inverted_index":{"Accurate":[0],"segmentation":[1,59,64,100,118,175,188,238],"of":[2,41,119,128,160,190,228,242],"organs":[3,43],"at":[4],"risk":[5],"(OARs)":[6],"from":[7,150],"head":[8],"and":[9,54,117,157,174,177,184,207,232,235],"neck":[10],"(H&N)":[11],"CT":[12,124,161,230],"images":[13,231],"is":[14,66,131,143],"crucial":[15],"for":[16,92,114,240],"effective":[17],"H&N":[18,123,229],"cancer":[19],"radiotherapy.":[20],"However,":[21],"the":[22,39,71,74,84,96,171,187,209,218],"existing":[23,85],"deep":[24],"learning":[25],"methods":[26,86],"are":[27],"often":[28,76,87],"not":[29],"trained":[30],"in":[31,180],"an":[32,181],"end-to-end":[33,182],"fashion,":[34,183],"i.e.,":[35],"they":[36],"independently":[37],"predetermine":[38],"regions":[40],"target":[42],"before":[44],"organ":[45],"segmentation,":[46],"causing":[47],"limited":[48],"information":[49],"sharing":[50],"between":[51,98],"related":[52],"tasks":[53,176],"thus":[55],"leading":[56],"to":[57,68,145,215],"suboptimal":[58],"results.":[60],"Furthermore,":[61],"when":[62],"conventional":[63],"network":[65,140],"used":[67,144],"segment":[69,216],"all":[70,217],"OARs":[72,79,121,172,192,219,241],"simultaneously,":[73],"results":[75,189],"favor":[77],"big":[78],"over":[80],"small":[81],"OARs.":[82],"Thus,":[83],"train":[88],"a":[89,108,132,194],"specific":[90],"model":[91],"each":[93,151],"OAR,":[94],"ignoring":[95],"correlation":[97],"different":[99],"tasks.":[101],"To":[102],"address":[103],"these":[104],"issues,":[105],"we":[106],"propose":[107],"new":[109],"multi-view":[110,200,211],"spatial":[111,201],"aggregation":[112,202],"framework":[113,130,203,224],"joint":[115],"localization":[116,173],"multiple":[120],"using":[122,225],"images.":[125,162],"The":[126],"core":[127],"our":[129,164,223],"proposed":[133],"region-of-interest":[134],"(ROI)-based":[135],"fine-grained":[136,166,197],"representation":[137,167],"convolutional":[138],"neural":[139],"(CNN),":[141],"which":[142],"generate":[146],"multi-OAR":[147,212],"probability":[148,213],"maps":[149,214],"2D":[152],"view":[153],"(i.e.,":[154],"axial,":[155],"coronal,":[156],"sagittal":[158],"view)":[159],"Specifically,":[163],"ROI-based":[165,196],"CNN":[168],"(1)":[169],"unifies":[170],"trains":[178],"them":[179],"(2)":[185],"improves":[186],"various-sized":[191],"via":[193],"novel":[195],"representation.":[198],"Our":[199],"then":[204],"spatially":[205],"aggregates":[206],"assembles":[208],"generated":[210],"simultaneously.":[220],"We":[221],"evaluate":[222],"two":[226],"sets":[227],"achieve":[233],"competitive":[234],"highly":[236],"robust":[237],"performance":[239],"various":[243],"sizes.":[244]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
