{"id":"https://openalex.org/W2999106318","doi":"https://doi.org/10.1109/tmi.2020.2964310","title":"Deep Learning of Imaging Phenotype and Genotype for Predicting Overall Survival Time of Glioblastoma Patients","display_name":"Deep Learning of Imaging Phenotype and Genotype for Predicting Overall Survival Time of Glioblastoma Patients","publication_year":2020,"publication_date":"2020-01-06","ids":{"openalex":"https://openalex.org/W2999106318","doi":"https://doi.org/10.1109/tmi.2020.2964310","mag":"2999106318","pmid":"https://pubmed.ncbi.nlm.nih.gov/31905135"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2020.2964310","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2020.2964310","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7289674","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101553435","display_name":"Zhenyu Tang","orcid":"https://orcid.org/0000-0002-6998-2669"},"institutions":[{"id":"https://openalex.org/I4210165198","display_name":"Beijing Advanced Sciences and Innovation Center","ror":"https://ror.org/05qm21180","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165198"]},{"id":"https://openalex.org/I82880672","display_name":"Beihang University","ror":"https://ror.org/00wk2mp56","country_code":"CN","type":"education","lineage":["https://openalex.org/I82880672"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhenyu Tang","raw_affiliation_strings":["Beijing Advanced Innovation Center for Big Data and Brain Computing, Beihang University, Beijing, China"],"affiliations":[{"raw_affiliation_string":"Beijing Advanced Innovation Center for Big Data and Brain Computing, Beihang University, Beijing, China","institution_ids":["https://openalex.org/I4210165198","https://openalex.org/I82880672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101659209","display_name":"Yuyun Xu","orcid":"https://orcid.org/0000-0003-2818-852X"},"institutions":[{"id":"https://openalex.org/I4210131061","display_name":"Zhejiang Provincial People's Hospital","ror":"https://ror.org/03k14e164","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131061"]},{"id":"https://openalex.org/I4210165441","display_name":"Hangzhou Medical College","ror":"https://ror.org/05gpas306","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210165441"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuyun Xu","raw_affiliation_strings":["Hangzhou Medical College, Hangzhou, China","Zhejiang Provincial People\u2019s Hospital, Hangzhou, China","Zhejiang Provincial People's Hospital, Hangzhou, China"],"affiliations":[{"raw_affiliation_string":"Hangzhou Medical College, Hangzhou, China","institution_ids":["https://openalex.org/I4210165441"]},{"raw_affiliation_string":"Zhejiang Provincial People\u2019s Hospital, Hangzhou, China","institution_ids":["https://openalex.org/I4210131061"]},{"raw_affiliation_string":"Zhejiang Provincial People's Hospital, Hangzhou, China","institution_ids":["https://openalex.org/I4210131061"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lei Jin","orcid":"https://orcid.org/0000-0001-7951-1521"},"institutions":[{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lei Jin","raw_affiliation_strings":["Neurologic Surgery Department, Glioma Surgery Division, Huashan Hospital, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Neurologic Surgery Department, Glioma Surgery Division, Huashan Hospital, Shanghai, China","institution_ids":["https://openalex.org/I4210159575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114036232","display_name":"Abudumijiti Aibaidula","orcid":null},"institutions":[{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Abudumijiti Aibaidula","raw_affiliation_strings":["Neurologic Surgery Department, Glioma Surgery Division, Huashan Hospital, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Neurologic Surgery Department, Glioma Surgery Division, Huashan Hospital, Shanghai, China","institution_ids":["https://openalex.org/I4210159575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035848394","display_name":"Junfeng Lu","orcid":"https://orcid.org/0000-0002-6091-5742"},"institutions":[{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junfeng Lu","raw_affiliation_strings":["Neurologic Surgery Department, Glioma Surgery Division, Huashan Hospital, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Neurologic Surgery Department, Glioma Surgery Division, Huashan Hospital, Shanghai, China","institution_ids":["https://openalex.org/I4210159575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052716839","display_name":"Zhicheng Jiao","orcid":"https://orcid.org/0000-0002-6968-0919"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhicheng Jiao","raw_affiliation_strings":["Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, USA"],"affiliations":[{"raw_affiliation_string":"Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011184859","display_name":"Jinsong Wu","orcid":"https://orcid.org/0000-0001-7854-9798"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210097554","display_name":"Center for Excellence in Brain Science and Intelligence Technology","ror":"https://ror.org/00vpwhm04","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210097554"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinsong Wu","raw_affiliation_strings":["Brain Function Laboratory, Neurosurgical Institute, Fudan University, Shanghai, China","Neurologic Surgery Department, Glioma Surgery Division, Huashan Hospital, Shanghai, China","Zhangjiang Laboratory, Institute of Brain-Intelligence Technology, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Brain Function Laboratory, Neurosurgical Institute, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"Neurologic Surgery Department, Glioma Surgery Division, Huashan Hospital, Shanghai, China","institution_ids":["https://openalex.org/I4210159575"]},{"raw_affiliation_string":"Zhangjiang Laboratory, Institute of Brain-Intelligence Technology, Shanghai, China","institution_ids":["https://openalex.org/I4210097554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108049200","display_name":"Han Zhang","orcid":"https://orcid.org/0000-0002-6645-8810"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Han Zhang","raw_affiliation_strings":["Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, USA"],"affiliations":[{"raw_affiliation_string":"Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000937401","display_name":"Dinggang Shen","orcid":"https://orcid.org/0000-0002-7934-5698"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR","US"],"is_corresponding":false,"raw_author_name":"Dinggang Shen","raw_affiliation_strings":["Department of Brain and Cognitive Engineering, Korea University, Seoul, South Korea","Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, USA"],"affiliations":[{"raw_affiliation_string":"Department of Brain and Cognitive Engineering, Korea University, Seoul, South Korea","institution_ids":["https://openalex.org/I197347611"]},{"raw_affiliation_string":"Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, USA","institution_ids":["https://openalex.org/I114027177"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5101553435"],"corresponding_institution_ids":["https://openalex.org/I4210165198","https://openalex.org/I82880672"],"apc_list":null,"apc_paid":null,"fwci":6.3584,"has_fulltext":false,"cited_by_count":102,"citation_normalized_percentile":{"value":0.97493906,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"39","issue":"6","first_page":"2100","last_page":"2109"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9890999794006348,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiogenomics","display_name":"Radiogenomics","score":0.7663701772689819},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.7428462505340576},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.6763806939125061},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.6199841499328613},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.6010738611221313},{"id":"https://openalex.org/keywords/glioblastoma","display_name":"Glioblastoma","score":0.5851303339004517},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5569754838943481},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"Neuroimaging","score":0.5401512384414673},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5292149186134338},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5005064010620117},{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.47855764627456665},{"id":"https://openalex.org/keywords/brain-tumor","display_name":"Brain tumor","score":0.44240546226501465},{"id":"https://openalex.org/keywords/medical-imaging","display_name":"Medical imaging","score":0.4246867001056671},{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"Personalized medicine","score":0.4170008897781372},{"id":"https://openalex.org/keywords/recurrent-neural-network","display_name":"Recurrent neural network","score":0.4164387583732605},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.3688081204891205},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.30803942680358887},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.2517976760864258},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.21517091989517212},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.19317218661308289},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.16300150752067566},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.13619175553321838},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.11511889100074768},{"id":"https://openalex.org/keywords/radiomics","display_name":"Radiomics","score":0.10900929570198059}],"concepts":[{"id":"https://openalex.org/C163500349","wikidata":"https://www.wikidata.org/wiki/Q7281263","display_name":"Radiogenomics","level":3,"score":0.7663701772689819},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.7428462505340576},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.6763806939125061},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.6199841499328613},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.6010738611221313},{"id":"https://openalex.org/C2776194525","wikidata":"https://www.wikidata.org/wiki/Q282142","display_name":"Glioblastoma","level":2,"score":0.5851303339004517},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5569754838943481},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.5401512384414673},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5292149186134338},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5005064010620117},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.47855764627456665},{"id":"https://openalex.org/C2779130545","wikidata":"https://www.wikidata.org/wiki/Q233309","display_name":"Brain tumor","level":2,"score":0.44240546226501465},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.4246867001056671},{"id":"https://openalex.org/C32220436","wikidata":"https://www.wikidata.org/wiki/Q2072214","display_name":"Personalized medicine","level":2,"score":0.4170008897781372},{"id":"https://openalex.org/C147168706","wikidata":"https://www.wikidata.org/wiki/Q1457734","display_name":"Recurrent neural network","level":3,"score":0.4164387583732605},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.3688081204891205},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30803942680358887},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2517976760864258},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.21517091989517212},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.19317218661308289},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.16300150752067566},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13619175553321838},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11511889100074768},{"id":"https://openalex.org/C2778559731","wikidata":"https://www.wikidata.org/wiki/Q23808793","display_name":"Radiomics","level":2,"score":0.10900929570198059},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/tmi.2020.2964310","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2020.2964310","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:31905135","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31905135","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:7289674","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7289674","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Med Imaging","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7289674","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7289674","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Med Imaging","raw_type":"Text"},"sustainable_development_goals":[{"score":0.41999998688697815,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":76,"referenced_works":["https://openalex.org/W273955616","https://openalex.org/W1510168180","https://openalex.org/W1568793698","https://openalex.org/W1641498739","https://openalex.org/W1680392829","https://openalex.org/W1763022604","https://openalex.org/W1881549354","https://openalex.org/W1897243882","https://openalex.org/W1902059139","https://openalex.org/W1971735090","https://openalex.org/W1979300931","https://openalex.org/W1984503751","https://openalex.org/W1990337776","https://openalex.org/W2000269560","https://openalex.org/W2008056655","https://openalex.org/W2015660037","https://openalex.org/W2019154144","https://openalex.org/W2035021866","https://openalex.org/W2040458067","https://openalex.org/W2044197183","https://openalex.org/W2067825653","https://openalex.org/W2071664396","https://openalex.org/W2071690225","https://openalex.org/W2092919444","https://openalex.org/W2097475056","https://openalex.org/W2099742943","https://openalex.org/W2103168300","https://openalex.org/W2117699623","https://openalex.org/W2121942316","https://openalex.org/W2123299008","https://openalex.org/W2139984188","https://openalex.org/W2148977460","https://openalex.org/W2149409455","https://openalex.org/W2151140401","https://openalex.org/W2162615325","https://openalex.org/W2163605009","https://openalex.org/W2163859522","https://openalex.org/W2164801635","https://openalex.org/W2174661749","https://openalex.org/W2229833142","https://openalex.org/W2346352626","https://openalex.org/W2461805626","https://openalex.org/W2465688795","https://openalex.org/W2513843238","https://openalex.org/W2518419661","https://openalex.org/W2525157777","https://openalex.org/W2526998669","https://openalex.org/W2585426403","https://openalex.org/W2751069891","https://openalex.org/W2751210549","https://openalex.org/W2758383347","https://openalex.org/W2760969998","https://openalex.org/W2767128594","https://openalex.org/W2774207949","https://openalex.org/W2782757127","https://openalex.org/W2786447217","https://openalex.org/W2787206897","https://openalex.org/W2790168597","https://openalex.org/W2790522557","https://openalex.org/W2796857898","https://openalex.org/W2889488215","https://openalex.org/W2911964244","https://openalex.org/W2912884588","https://openalex.org/W2967184931","https://openalex.org/W4230172521","https://openalex.org/W4293241248","https://openalex.org/W4300465534","https://openalex.org/W6610017368","https://openalex.org/W6637386731","https://openalex.org/W6639490048","https://openalex.org/W6661324352","https://openalex.org/W6682376995","https://openalex.org/W6684191040","https://openalex.org/W6744169265","https://openalex.org/W6748259793","https://openalex.org/W6748501025"],"related_works":["https://openalex.org/W2594804317","https://openalex.org/W3031917654","https://openalex.org/W2791434829","https://openalex.org/W2803669118","https://openalex.org/W4205914284","https://openalex.org/W2790233990","https://openalex.org/W2252911892","https://openalex.org/W2271119709","https://openalex.org/W3088261055","https://openalex.org/W3193504098"],"abstract_inverted_index":{"Glioblastoma":[0],"(GBM)":[1],"is":[2,21,78,83],"the":[3,40,60,69,80,146,158,169,196],"most":[4],"common":[5],"and":[6,120,140],"deadly":[7],"malignant":[8],"brain":[9,118,173],"tumor.":[10],"For":[11],"personalized":[12],"treatment,":[13],"an":[14],"accurate":[15],"pre-operative":[16,41,112],"prognosis":[17],"for":[18,102,155],"GBM":[19,51,103,177],"patients":[20],"highly":[22],"desired.":[23],"Recently,":[24],"many":[25,181],"machine":[26],"learning-based":[27,98],"methods":[28],"have":[29],"been":[30,53,66],"adopted":[31],"to":[32,55,123,135,189,202],"predict":[33],"overall":[34],"survival":[35],"(OS)":[36],"time":[37,163],"based":[38],"on":[39],"mono-":[42],"or":[43],"multi-modal":[44],"imaging":[45,116],"phenotype.":[46],"The":[47,75],"genotypic":[48],"information":[49],"of":[50,59,160,175],"has":[52,64],"proven":[54],"be":[56,165],"strongly":[57],"indicative":[58],"prognosis;":[61],"however,":[62],"this":[63,91],"not":[65],"considered":[67],"in":[68],"existing":[70],"imaging-based":[71],"OS":[72,99,124,141,162,198],"prediction":[73,100,142,199],"methods.":[74,205],"main":[76],"reason":[77],"that":[79],"tumor":[81,108,138,152],"genotype":[82,139,156],"unavailable":[84],"pre-operatively":[85],"unless":[86],"deriving":[87],"from":[88,111,150],"craniotomy.":[89],"In":[90,168],"paper,":[92],"we":[93,127],"propose":[94,128],"a":[95,129],"new":[96],"deep":[97],"method":[101,194],"patients,":[104,178],"which":[105],"can":[106,148,164],"derive":[107],"genotype-related":[109,153],"features":[110,154],"multimodal":[113,171],"magnetic":[114],"resonance":[115],"(MRI)":[117],"data":[119],"feed":[121],"them":[122],"prediction.":[125],"Specifically,":[126],"multi-task":[130],"convolutional":[131],"neural":[132],"network":[133,147],"(CNN)":[134],"accomplish":[136],"both":[137],"tasks":[143],"jointly.":[144],"As":[145],"benefit":[149],"learning":[151],"prediction,":[157],"accuracy":[159,200],"predicting":[161],"prominently":[166],"improved.":[167],"experiments,":[170],"MRI":[172],"dataset":[174],"120":[176],"with":[179],"as":[180,182],"four":[183],"different":[184],"genotypic/molecular":[185],"biomarkers,":[186],"are":[187],"used":[188],"evaluate":[190],"our":[191],"method.":[192],"Our":[193],"achieves":[195],"highest":[197],"compared":[201],"other":[203],"state-of-the-art":[204]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":21},{"year":2024,"cited_by_count":18},{"year":2023,"cited_by_count":22},{"year":2022,"cited_by_count":19},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":5}],"updated_date":"2026-04-12T07:58:50.170612","created_date":"2025-10-10T00:00:00"}