{"id":"https://openalex.org/W2983970873","doi":"https://doi.org/10.1109/tmi.2019.2953054","title":"Deep Learning Analysis of Coronary Arteries in Cardiac CT Angiography for Detection of Patients Requiring Invasive Coronary Angiography","display_name":"Deep Learning Analysis of Coronary Arteries in Cardiac CT Angiography for Detection of Patients Requiring Invasive Coronary Angiography","publication_year":2019,"publication_date":"2019-11-12","ids":{"openalex":"https://openalex.org/W2983970873","doi":"https://doi.org/10.1109/tmi.2019.2953054","mag":"2983970873","pmid":"https://pubmed.ncbi.nlm.nih.gov/31725371"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2019.2953054","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2019.2953054","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"preprint","indexed_in":["arxiv","crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/1906.04419","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057331980","display_name":"Majd Zreik","orcid":"https://orcid.org/0000-0002-6739-3297"},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Majd Zreik","raw_affiliation_strings":["Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands","Image Sciences Institute, University Medical Center Utrecht, Utrecht, CS, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]},{"raw_affiliation_string":"Image Sciences Institute, University Medical Center Utrecht, Utrecht, CS, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063560179","display_name":"Robbert W. van Hamersvelt","orcid":"https://orcid.org/0000-0002-6084-0656"},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Robbert W. van Hamersvelt","raw_affiliation_strings":["Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands","Department of Radiology, University Medical Center Utrecht, Utrecht, CS, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]},{"raw_affiliation_string":"Department of Radiology, University Medical Center Utrecht, Utrecht, CS, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010819964","display_name":"Nadieh Khalili","orcid":null},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Nadieh Khalili","raw_affiliation_strings":["Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands","Image Sciences Institute, University Medical Center Utrecht, Utrecht, CS, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]},{"raw_affiliation_string":"Image Sciences Institute, University Medical Center Utrecht, Utrecht, CS, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028639654","display_name":"Jelmer M. Wolterink","orcid":"https://orcid.org/0000-0001-5505-475X"},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jelmer M. Wolterink","raw_affiliation_strings":["Department of Biomedical Engineering and Physics, Amsterdam University Medical Center, Amsterdam, The Netherlands","Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands","Image Sciences Institute, University Medical Center Utrecht, Utrecht, CS, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering and Physics, Amsterdam University Medical Center, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210151833"]},{"raw_affiliation_string":"Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]},{"raw_affiliation_string":"Image Sciences Institute, University Medical Center Utrecht, Utrecht, CS, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017351131","display_name":"Michiel Voskuil","orcid":"https://orcid.org/0000-0001-9285-9573"},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Michiel Voskuil","raw_affiliation_strings":["Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands","Utrecht University, Utrecht, The Netherlands","Department of Cardiology, University Medical Center Utrecht, Utrecht, CS, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]},{"raw_affiliation_string":"Utrecht University, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"Department of Cardiology, University Medical Center Utrecht, Utrecht, CS, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033933581","display_name":"Max A. Viergever","orcid":"https://orcid.org/0000-0003-2582-042X"},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Max A. Viergever","raw_affiliation_strings":["Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands","Utrecht University, Utrecht, The Netherlands","Image Sciences Institute, University Medical Center Utrecht, Utrecht, CS, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]},{"raw_affiliation_string":"Utrecht University, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"Image Sciences Institute, University Medical Center Utrecht, Utrecht, CS, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053071529","display_name":"Tim Leiner","orcid":"https://orcid.org/0000-0003-1885-5499"},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Tim Leiner","raw_affiliation_strings":["Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands","Utrecht University, Utrecht, The Netherlands","Department of Radiology, University Medical Center Utrecht, Utrecht, CS, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]},{"raw_affiliation_string":"Utrecht University, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"Department of Radiology, University Medical Center Utrecht, Utrecht, CS, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084070018","display_name":"Ivana I\u0161gum","orcid":"https://orcid.org/0000-0003-1869-5034"},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Ivana Isgum","raw_affiliation_strings":["Department of Biomedical Engineering and Physics, Amsterdam University Medical Center, Amsterdam, The Netherlands","Department of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands","Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands","Image Sciences Institute, University Medical Center Utrecht, Utrecht, CS, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering and Physics, Amsterdam University Medical Center, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210151833"]},{"raw_affiliation_string":"Department of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands","institution_ids":[]},{"raw_affiliation_string":"Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]},{"raw_affiliation_string":"Image Sciences Institute, University Medical Center Utrecht, Utrecht, CS, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5057331980"],"corresponding_institution_ids":["https://openalex.org/I3018483916"],"apc_list":null,"apc_paid":null,"fwci":1.028,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.78180023,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"39","issue":"5","first_page":"1545","last_page":"1557"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/coronary-arteries","display_name":"Coronary arteries","score":0.8542778491973877},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.789899468421936},{"id":"https://openalex.org/keywords/stenosis","display_name":"Stenosis","score":0.6369703412055969},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"Coronary artery disease","score":0.5885086059570312},{"id":"https://openalex.org/keywords/artery","display_name":"Artery","score":0.5594670176506042},{"id":"https://openalex.org/keywords/angiography","display_name":"Angiography","score":0.5264217257499695},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.49998974800109863},{"id":"https://openalex.org/keywords/fractional-flow-reserve","display_name":"Fractional flow reserve","score":0.4905375838279724},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.4847933351993561},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.46968013048171997},{"id":"https://openalex.org/keywords/coronary-angiography","display_name":"Coronary angiography","score":0.3270876705646515},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"Myocardial infarction","score":0.15892630815505981}],"concepts":[{"id":"https://openalex.org/C2778742706","wikidata":"https://www.wikidata.org/wiki/Q18361829","display_name":"Coronary arteries","level":3,"score":0.8542778491973877},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.789899468421936},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.6369703412055969},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.5885086059570312},{"id":"https://openalex.org/C2776820930","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Artery","level":2,"score":0.5594670176506042},{"id":"https://openalex.org/C2780643987","wikidata":"https://www.wikidata.org/wiki/Q468414","display_name":"Angiography","level":2,"score":0.5264217257499695},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.49998974800109863},{"id":"https://openalex.org/C2777987666","wikidata":"https://www.wikidata.org/wiki/Q1440572","display_name":"Fractional flow reserve","level":4,"score":0.4905375838279724},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4847933351993561},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46968013048171997},{"id":"https://openalex.org/C3019004856","wikidata":"https://www.wikidata.org/wiki/Q42297149","display_name":"Coronary angiography","level":3,"score":0.3270876705646515},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.15892630815505981}],"mesh":[{"descriptor_ui":"D000072226","descriptor_name":"Computed Tomography Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072226","descriptor_name":"Computed Tomography Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072226","descriptor_name":"Computed Tomography Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017023","descriptor_name":"Coronary Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017023","descriptor_name":"Coronary Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017023","descriptor_name":"Coronary Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053805","descriptor_name":"Fractional Flow Reserve, Myocardial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053805","descriptor_name":"Fractional Flow Reserve, Myocardial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053805","descriptor_name":"Fractional Flow Reserve, Myocardial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":8,"locations":[{"id":"doi:10.1109/tmi.2019.2953054","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2019.2953054","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:31725371","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31725371","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null},{"id":"pmh:oai:arXiv.org:1906.04419","is_oa":true,"landing_page_url":"http://arxiv.org/abs/1906.04419","pdf_url":"https://arxiv.org/pdf/1906.04419","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"pmh:oai:pure.amsterdamumc.nl:publications/0b1ca08f-3acc-4e75-afcb-f4c4c71d48b8","is_oa":true,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/0b1ca08f-3acc-4e75-afcb-f4c4c71d48b8","pdf_url":"https://pure.amsterdamumc.nl/files/155921195/Deep-learning-analysis-of-coronary-arteries-in-cardiac-ct-angiography-for-detection-of-patients-requiring-invasive-coron.pdf","source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Zreik, M, van Hamersvelt, R W, Khalili, N, Wolterink, J M, Voskuil, M, Viergever, M A, Leiner, T & Isgum, I 2020, 'Deep Learning Analysis of Coronary Arteries in Cardiac CT Angiography for Detection of Patients Requiring Invasive Coronary Angiography', IEEE transactions on medical imaging, vol. 39, no. 5, 8896989, pp. 1545-1557. https://doi.org/10.1109/TMI.2019.2953054","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:amcpub:oai:pure.amc.nl:publications/057ae4ed-ccc2-494f-8110-399b6c0e337c","is_oa":true,"landing_page_url":"https://pure.amc.nl/en/publications/deep-learning-analysis-of-coronary-arteries-in-cardiac-ct-angiography-for-detection-of-patients-requiring-invasive-coronary-angiography(057ae4ed-ccc2-494f-8110-399b6c0e337c).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE transactions on medical imaging, 39(5):8896989, 1545 - 1557. Institute of Electrical and Electronics Engineers Inc.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:amcpub:oai:pure.amc.nl:publications/874b6e06-3508-442c-8d00-1c9b2efb9e99","is_oa":false,"landing_page_url":"https://pure.amc.nl/en/publications/deep-learning-analysis-of-coronary-arteries-in-cardiac-ct-angiography-for-detection-of-patients-requiring-invasive-coronary-angiography(874b6e06-3508-442c-8d00-1c9b2efb9e99).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE transactions on medical imaging, 39(5), 1545 - 1557. Institute of Electrical and Electronics Engineers Inc.","raw_type":"info:eu-repo/semantics/article"},{"id":"doi:10.48550/arxiv.1906.04419","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.1906.04419","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article"},{"id":"mag:2983970873","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:arXiv.org:1906.04419","is_oa":true,"landing_page_url":"http://arxiv.org/abs/1906.04419","pdf_url":"https://arxiv.org/pdf/1906.04419","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7599999904632568}],"awards":[{"id":"https://openalex.org/G684346720","display_name":null,"funder_award_id":"104003009","funder_id":"https://openalex.org/F4320321007","funder_display_name":"ZonMw"},{"id":"https://openalex.org/G6914820615","display_name":null,"funder_award_id":"1040030","funder_id":"https://openalex.org/F4320321007","funder_display_name":"ZonMw"}],"funders":[{"id":"https://openalex.org/F4320321007","display_name":"ZonMw","ror":"https://ror.org/01yaj9a77"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W49580647","https://openalex.org/W127494906","https://openalex.org/W161598465","https://openalex.org/W185443885","https://openalex.org/W359807119","https://openalex.org/W1260204519","https://openalex.org/W1522301498","https://openalex.org/W1540562167","https://openalex.org/W1836465849","https://openalex.org/W2008103786","https://openalex.org/W2013832297","https://openalex.org/W2046115776","https://openalex.org/W2064675550","https://openalex.org/W2068053518","https://openalex.org/W2082304218","https://openalex.org/W2107275754","https://openalex.org/W2110756756","https://openalex.org/W2115416118","https://openalex.org/W2118810625","https://openalex.org/W2119821739","https://openalex.org/W2130942839","https://openalex.org/W2132401137","https://openalex.org/W2136655611","https://openalex.org/W2141408670","https://openalex.org/W2155007397","https://openalex.org/W2157331557","https://openalex.org/W2161812533","https://openalex.org/W2163922914","https://openalex.org/W2165023525","https://openalex.org/W2166538393","https://openalex.org/W2320707747","https://openalex.org/W2324798816","https://openalex.org/W2335916523","https://openalex.org/W2407173596","https://openalex.org/W2422494935","https://openalex.org/W2557283755","https://openalex.org/W2606285014","https://openalex.org/W2754657547","https://openalex.org/W2769042349","https://openalex.org/W2791453970","https://openalex.org/W2807965844","https://openalex.org/W2886584550","https://openalex.org/W2895401428","https://openalex.org/W2901903036","https://openalex.org/W2919115771","https://openalex.org/W2949416428","https://openalex.org/W2951004968","https://openalex.org/W2963046541","https://openalex.org/W2963231672","https://openalex.org/W2963397057","https://openalex.org/W3098809754","https://openalex.org/W4239510810","https://openalex.org/W4256714814","https://openalex.org/W6631190155","https://openalex.org/W6638667902","https://openalex.org/W6640963894","https://openalex.org/W6675944832","https://openalex.org/W6679436768","https://openalex.org/W6755875945"],"related_works":["https://openalex.org/W2987614960","https://openalex.org/W3130183364","https://openalex.org/W3098809754","https://openalex.org/W2892179333","https://openalex.org/W3006078122","https://openalex.org/W2114782775","https://openalex.org/W3010018504","https://openalex.org/W3186953906","https://openalex.org/W2114225307","https://openalex.org/W2364464050","https://openalex.org/W3029145205","https://openalex.org/W3031126751","https://openalex.org/W2797377773","https://openalex.org/W2462272338","https://openalex.org/W2369011583","https://openalex.org/W2337499961","https://openalex.org/W2357652553","https://openalex.org/W2378668198","https://openalex.org/W1999656282","https://openalex.org/W2967267431"],"abstract_inverted_index":{"In":[0],"patients":[1,48,215,232],"with":[2,122],"obstructive":[3],"coronary":[4,12,35,57,83,99,105,171,222],"artery":[5,13,223],"disease,":[6],"the":[7,94,98,104,186,196,203,208,229],"functional":[8,95],"significance":[9,96],"of":[10,47,55,70,74,97,103,138,170,191,210,214,231],"a":[11,40,90,135,163],"stenosis":[14,125],"needs":[15],"to":[16,19,111,159],"be":[17],"determined":[18],"guide":[20],"treatment.":[21],"This":[22,225],"is":[23],"typically":[24],"established":[25],"through":[26],"fractional":[27],"flow":[28],"reserve":[29],"(FFR)":[30],"measurement,":[31],"performed":[32],"during":[33],"invasive":[34,77,174],"angiography":[36,62],"(ICA).":[37],"We":[38,65],"present":[39],"method":[41],"for":[42,93],"automatic":[43,211],"and":[44,109,144,150,198,219],"non-invasive":[45,212],"detection":[46,169,213],"requiring":[49,173],"ICA,":[50,128],"employing":[51],"deep":[52],"unsupervised":[53],"analysis":[54],"complete":[56],"arteries":[58,106,121,161,172],"in":[59,80,182],"cardiac":[60],"CT":[61],"(CCTA)":[63],"images.":[64],"retrospectively":[66],"collected":[67],"CCTA":[68],"scans":[69],"187":[71],"patients,":[72],"137":[73],"them":[75],"underwent":[76],"FFR":[78,86],"measurement":[79],"192":[81],"different":[82],"arteries.":[84],"These":[85],"measurements":[87],"served":[88],"as":[89],"reference":[91],"standard":[92],"stenosis.":[100],"The":[101,168,205],"centerlines":[102],"were":[107,157],"extracted":[108],"used":[110],"reconstruct":[112],"straightened":[113],"multi-planar":[114],"reformatted":[115],"(MPR)":[116],"volumes.":[117],"To":[118],"automatically":[119],"identify":[120],"functionally":[123],"significant":[124],"that":[126,216,233],"require":[127,217],"each":[129],"MPR":[130],"volume":[131],"was":[132],"encoded":[133],"into":[134],"fixed":[136],"number":[137,230],"encodings":[139,156],"using":[140,162,177],"two":[141],"disjoint":[142],"3D":[143],"1D":[145],"convolutional":[146],"autoencoders":[147],"performing":[148],"spatial":[149],"sequential":[151],"encodings,":[152],"respectively.":[153],"Thereafter,":[154],"these":[155],"employed":[158],"classify":[160],"support":[164],"vector":[165],"machine":[166],"classifier.":[167],"evaluation,":[175],"evaluated":[176],"repeated":[178],"cross-validation":[179],"experiments,":[180],"resulted":[181],"an":[183],"area":[184],"under":[185],"receiver":[187],"operating":[188],"characteristic":[189],"curve":[190],"0.81":[192],"\u00b1":[193,200],"0.02":[194,201],"on":[195,202],"artery-level,":[197],"0.87":[199],"patient-level.":[204],"results":[206],"demonstrate":[207],"feasibility":[209],"ICA":[218],"possibly":[220],"subsequent":[221],"intervention.":[224],"could":[226],"potentially":[227],"reduce":[228],"unnecessarily":[234],"undergo":[235],"ICA.":[236]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}