{"id":"https://openalex.org/W2939171697","doi":"https://doi.org/10.1109/tmi.2019.2910386","title":"Multi-Exponential Relaxometry Using $\\ell_{{1}}$ -Regularized Iterative NNLS (MERLIN) With Application to Myelin Water Fraction Imaging","display_name":"Multi-Exponential Relaxometry Using $\\ell_{{1}}$ -Regularized Iterative NNLS (MERLIN) With Application to Myelin Water Fraction Imaging","publication_year":2019,"publication_date":"2019-04-17","ids":{"openalex":"https://openalex.org/W2939171697","doi":"https://doi.org/10.1109/tmi.2019.2910386","mag":"2939171697","pmid":"https://pubmed.ncbi.nlm.nih.gov/30990178"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2019.2910386","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2019.2910386","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083251698","display_name":"Markus Zimmermann","orcid":"https://orcid.org/0000-0003-1273-5218"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Markus Zimmermann","raw_affiliation_strings":["Institute of Neuroscience and Medicine 4, Forschungszentrum J\u00fclich, J\u00fclich, Germany"],"raw_orcid":"https://orcid.org/0000-0003-1273-5218","affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Medicine 4, Forschungszentrum J\u00fclich, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064737523","display_name":"Ana\u2010Maria Oros\u2010Peusquens","orcid":"https://orcid.org/0000-0002-8536-8044"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ana-Maria Oros-Peusquens","raw_affiliation_strings":["Institute of Neuroscience and Medicine 4, Forschungszentrum J\u00fclich, J\u00fclich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Medicine 4, Forschungszentrum J\u00fclich, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078298339","display_name":"Elene Iordanishvili","orcid":"https://orcid.org/0000-0001-5937-3790"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Elene Iordanishvili","raw_affiliation_strings":["Institute of Neuroscience and Medicine 4, Forschungszentrum J\u00fclich, J\u00fclich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Medicine 4, Forschungszentrum J\u00fclich, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038634573","display_name":"Seonyeong Shin","orcid":null},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Seonyeong Shin","raw_affiliation_strings":["Institute of Neuroscience and Medicine 4, Forschungszentrum J\u00fclich, J\u00fclich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Medicine 4, Forschungszentrum J\u00fclich, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007753703","display_name":"Seong Dae Yun","orcid":"https://orcid.org/0000-0001-7398-1899"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Seong Dae Yun","raw_affiliation_strings":["Institute of Neuroscience and Medicine 4, Forschungszentrum J\u00fclich, J\u00fclich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Medicine 4, Forschungszentrum J\u00fclich, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015869273","display_name":"Zaheer Abbas","orcid":"https://orcid.org/0000-0002-0650-8388"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]},{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Zaheer Abbas","raw_affiliation_strings":["Department of Neurology, RWTH Aachen University, Aachen, Germany","Institute of Neuroscience and Medicine 4, Forschungszentrum J\u00fclich, J\u00fclich, Germany"],"raw_orcid":"https://orcid.org/0000-0002-0650-8388","affiliations":[{"raw_affiliation_string":"Department of Neurology, RWTH Aachen University, Aachen, Germany","institution_ids":["https://openalex.org/I887968799"]},{"raw_affiliation_string":"Institute of Neuroscience and Medicine 4, Forschungszentrum J\u00fclich, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071643772","display_name":"N. Jon Shah","orcid":"https://orcid.org/0000-0002-8151-6169"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]},{"id":"https://openalex.org/I4210133912","display_name":"J\u00fclich Aachen Research Alliance","ror":"https://ror.org/02r0e4r58","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758","https://openalex.org/I4210133912"]},{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"N. Jon Shah","raw_affiliation_strings":["Department of Neurology, RWTH Aachen University, Aachen, Germany","Institute of Neuroscience and Medicine 4, Forschungszentrum J\u00fclich, J\u00fclich, Germany","JARA, Forschungszentrum J\u00fclich, Institute of Neuroscience and Medicine 11, J\u00fclich, Germany","JARA-BRAIN Institute of Translational Medicine, Aachen, Germany"],"raw_orcid":"https://orcid.org/0000-0002-8151-6169","affiliations":[{"raw_affiliation_string":"Department of Neurology, RWTH Aachen University, Aachen, Germany","institution_ids":["https://openalex.org/I887968799"]},{"raw_affiliation_string":"Institute of Neuroscience and Medicine 4, Forschungszentrum J\u00fclich, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]},{"raw_affiliation_string":"JARA, Forschungszentrum J\u00fclich, Institute of Neuroscience and Medicine 11, J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]},{"raw_affiliation_string":"JARA-BRAIN Institute of Translational Medicine, Aachen, Germany","institution_ids":["https://openalex.org/I4210133912"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5083251698"],"corresponding_institution_ids":["https://openalex.org/I171892758"],"apc_list":null,"apc_paid":null,"fwci":0.7144,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.74478477,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"38","issue":"11","first_page":"2676","last_page":"2686"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10688","display_name":"Image and Signal Denoising Methods","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10688","display_name":"Image and Signal Denoising Methods","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12603","display_name":"NMR spectroscopy and applications","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/3106","display_name":"Nuclear and High Energy Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11205","display_name":"Numerical methods in inverse problems","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/2610","display_name":"Mathematical Physics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/relaxometry","display_name":"Relaxometry","score":0.7252293825149536},{"id":"https://openalex.org/keywords/exponential-function","display_name":"Exponential function","score":0.6225054860115051},{"id":"https://openalex.org/keywords/iterative-reconstruction","display_name":"Iterative reconstruction","score":0.47757890820503235},{"id":"https://openalex.org/keywords/myelin","display_name":"Myelin","score":0.4604829251766205},{"id":"https://openalex.org/keywords/fraction","display_name":"Fraction (chemistry)","score":0.4583333134651184},{"id":"https://openalex.org/keywords/iterative-method","display_name":"Iterative method","score":0.4505241811275482},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.4347354769706726},{"id":"https://openalex.org/keywords/nuclear-magnetic-resonance","display_name":"Nuclear magnetic resonance","score":0.4223119914531708},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.397106796503067},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.32631945610046387},{"id":"https://openalex.org/keywords/mathematical-analysis","display_name":"Mathematical analysis","score":0.27873414754867554},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.2729104161262512},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.26813650131225586},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.26123613119125366},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.23319539427757263},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.18280646204948425},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.15459796786308289},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.10944744944572449},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.10807189345359802}],"concepts":[{"id":"https://openalex.org/C73286259","wikidata":"https://www.wikidata.org/wiki/Q7310885","display_name":"Relaxometry","level":4,"score":0.7252293825149536},{"id":"https://openalex.org/C151376022","wikidata":"https://www.wikidata.org/wiki/Q168698","display_name":"Exponential function","level":2,"score":0.6225054860115051},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.47757890820503235},{"id":"https://openalex.org/C2778609137","wikidata":"https://www.wikidata.org/wiki/Q105790271","display_name":"Myelin","level":3,"score":0.4604829251766205},{"id":"https://openalex.org/C149629883","wikidata":"https://www.wikidata.org/wiki/Q660926","display_name":"Fraction (chemistry)","level":2,"score":0.4583333134651184},{"id":"https://openalex.org/C159694833","wikidata":"https://www.wikidata.org/wiki/Q2321565","display_name":"Iterative method","level":2,"score":0.4505241811275482},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.4347354769706726},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.4223119914531708},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.397106796503067},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.32631945610046387},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.27873414754867554},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2729104161262512},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.26813650131225586},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.26123613119125366},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.23319539427757263},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.18280646204948425},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15459796786308289},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.10944744944572449},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10807189345359802},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.0},{"id":"https://openalex.org/C83042744","wikidata":"https://www.wikidata.org/wiki/Q904043","display_name":"Spin echo","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001834","descriptor_name":"Body Water","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001834","descriptor_name":"Body Water","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001834","descriptor_name":"Body Water","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009186","descriptor_name":"Myelin Sheath","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009186","descriptor_name":"Myelin Sheath","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009186","descriptor_name":"Myelin Sheath","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tmi.2019.2910386","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2019.2910386","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:30990178","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30990178","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7200000286102295,"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W1513489978","https://openalex.org/W1562101002","https://openalex.org/W1967906448","https://openalex.org/W1971082159","https://openalex.org/W1974082131","https://openalex.org/W1974603254","https://openalex.org/W1980477024","https://openalex.org/W1986660440","https://openalex.org/W1991475061","https://openalex.org/W1996287810","https://openalex.org/W1999383339","https://openalex.org/W2000678814","https://openalex.org/W2009423817","https://openalex.org/W2011301426","https://openalex.org/W2011412251","https://openalex.org/W2013244508","https://openalex.org/W2027576059","https://openalex.org/W2035309554","https://openalex.org/W2045632597","https://openalex.org/W2046972731","https://openalex.org/W2061602594","https://openalex.org/W2061939373","https://openalex.org/W2080737598","https://openalex.org/W2092950440","https://openalex.org/W2103559027","https://openalex.org/W2107901445","https://openalex.org/W2128498965","https://openalex.org/W2142058898","https://openalex.org/W2146292423","https://openalex.org/W2153820018","https://openalex.org/W2158940042","https://openalex.org/W2164278908","https://openalex.org/W2166312597","https://openalex.org/W2169459006","https://openalex.org/W2404056086","https://openalex.org/W2483990523","https://openalex.org/W2626498913","https://openalex.org/W2729067655","https://openalex.org/W2739746216","https://openalex.org/W2758754714","https://openalex.org/W2767396100","https://openalex.org/W2795555249","https://openalex.org/W2800626254","https://openalex.org/W2802493769","https://openalex.org/W4214806317","https://openalex.org/W4292363360"],"related_works":["https://openalex.org/W3112223792","https://openalex.org/W1989212405","https://openalex.org/W4401570420","https://openalex.org/W4389011098","https://openalex.org/W2107386309","https://openalex.org/W2545869789","https://openalex.org/W2141090006","https://openalex.org/W1964555484","https://openalex.org/W3048932468","https://openalex.org/W2148504016"],"abstract_inverted_index":{"A":[0],"new":[1],"parameter":[2,75],"estimation":[3],"algorithm,":[4],"MERLIN,":[5],"is":[6,34,53,58,78,105,123],"presented":[7],"for":[8,160],"accurate":[9],"and":[10,42,55,63,72,95,109,136],"robust":[11],"multiexponential":[12],"relaxometry":[13,33],"using":[14,113],"magnetic":[15],"resonance":[16],"imaging,":[17],"a":[18,79,114,137],"tool":[19],"that":[20,84],"can":[21,43,67],"provide":[22],"valuable":[23],"insight":[24],"into":[25],"the":[26,30,38,50,99,126],"tissue":[27],"microstructure":[28],"of":[29,98,155,163],"brain.":[31],"Multi-exponential":[32],"used":[35],"to":[36,45,61,69,92,125,157],"analyze":[37],"myelin":[39],"water":[40],"fraction":[41],"help":[44],"detect":[46],"related":[47],"diseases.":[48],"However,":[49],"underlying":[51],"problem":[52],"ill-conditioned,":[54],"as":[56],"such,":[57],"extremely":[59],"sensitive":[60],"noise":[62],"measurement":[64],"imperfections,":[65],"which":[66],"lead":[68],"less":[70],"precise":[71],"more":[73],"biased":[74],"estimates.":[76],"MERLIN":[77,122],"fully":[80],"automated,":[81],"multi-voxel":[82],"approach":[83],"incorporates":[85],"state-of-the-art":[86],"\u2113":[87,129],"<sub":[88,130],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[89,131],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">1</sub>":[90],"-regularization":[91],"enforce":[93],"sparsity":[94],"spatial":[96,141],"consistency":[97],"estimated":[100],"distributions.":[101],"The":[102],"proposed":[103],"method":[104],"validated":[106],"in":[107,110,165],"simulations":[108],"vivo":[111],"experiments,":[112],"multi-echo":[115],"gradient-echo":[116],"(MEGE)":[117],"sequence":[118],"at":[119],"3":[120],"T.":[121],"compared":[124],"conventional":[127],"single-voxel":[128],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">2</sub>":[132],"-regularized":[133],"NNLS":[134],"(rNNLS)":[135],"multivoxel":[138],"extension":[139],"with":[140],"priors":[142],"(rNNLS":[143],"+":[144],"SP),":[145],"where":[146],"it":[147],"consistently":[148],"showed":[149],"lower":[150],"root":[151],"mean":[152],"squared":[153],"errors":[154],"up":[156],"70":[158],"percent":[159],"all":[161],"parameters":[162],"interest":[164],"these":[166],"simulations.":[167]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2}],"updated_date":"2026-05-16T08:24:45.110214","created_date":"2019-04-25T00:00:00"}