{"id":"https://openalex.org/W2889735150","doi":"https://doi.org/10.1109/tmi.2018.2867602","title":"Improved Photoacoustic-Based Oxygen Saturation Estimation With SNR-Regularized Local Fluence Correction","display_name":"Improved Photoacoustic-Based Oxygen Saturation Estimation With SNR-Regularized Local Fluence Correction","publication_year":2018,"publication_date":"2018-09-21","ids":{"openalex":"https://openalex.org/W2889735150","doi":"https://doi.org/10.1109/tmi.2018.2867602","mag":"2889735150","pmid":"https://pubmed.ncbi.nlm.nih.gov/30207951"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2018.2867602","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tmi.2018.2867602","pdf_url":"https://ieeexplore.ieee.org/ielx7/42/8632831/08458163.pdf","source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://ieeexplore.ieee.org/ielx7/42/8632831/08458163.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050527536","display_name":"Mohamed A. Naser","orcid":"https://orcid.org/0000-0003-1020-4966"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mohamed A. Naser","raw_affiliation_strings":["Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"],"raw_orcid":"https://orcid.org/0000-0003-1020-4966","affiliations":[{"raw_affiliation_string":"Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001245300","display_name":"Diego R. T. Sampaio","orcid":"https://orcid.org/0000-0002-3568-2828"},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Diego R. T. Sampaio","raw_affiliation_strings":["Department of Physics, University of Sao Paulo, Ribeirao Preto, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, University of Sao Paulo, Ribeirao Preto, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082364062","display_name":"Nina M. Mu\u00f1oz","orcid":"https://orcid.org/0000-0001-7733-4883"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nina M. Munoz","raw_affiliation_strings":["Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"],"raw_orcid":"https://orcid.org/0000-0001-7733-4883","affiliations":[{"raw_affiliation_string":"Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014606757","display_name":"Cayla Wood","orcid":"https://orcid.org/0000-0002-8445-3343"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cayla A. Wood","raw_affiliation_strings":["The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA"],"raw_orcid":"https://orcid.org/0000-0002-8445-3343","affiliations":[{"raw_affiliation_string":"The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I919571938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013437628","display_name":"Trevor Mitcham","orcid":"https://orcid.org/0000-0001-6985-5486"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Trevor M. Mitcham","raw_affiliation_strings":["The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I919571938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090718664","display_name":"Wolfgang Stefan","orcid":null},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wolfgang Stefan","raw_affiliation_strings":["Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005161326","display_name":"Konstantin Sokolov","orcid":"https://orcid.org/0000-0002-0198-2005"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Konstantin V. Sokolov","raw_affiliation_strings":["The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA"],"raw_orcid":"https://orcid.org/0000-0002-0198-2005","affiliations":[{"raw_affiliation_string":"The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I919571938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049990102","display_name":"Theo Z. Pavan","orcid":"https://orcid.org/0000-0002-9931-8558"},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Theo Z. Pavan","raw_affiliation_strings":["Department of Physics, University of Sao Paulo, Ribeirao Preto, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-9931-8558","affiliations":[{"raw_affiliation_string":"Department of Physics, University of Sao Paulo, Ribeirao Preto, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042362382","display_name":"Rony Avritscher","orcid":"https://orcid.org/0000-0002-5122-3445"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rony Avritscher","raw_affiliation_strings":["Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046922371","display_name":"Richard R. Bouchard","orcid":"https://orcid.org/0000-0003-4763-9875"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard R. Bouchard","raw_affiliation_strings":["The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA"],"raw_orcid":"https://orcid.org/0000-0003-4763-9875","affiliations":[{"raw_affiliation_string":"The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I919571938"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9382,"has_fulltext":true,"cited_by_count":41,"citation_normalized_percentile":{"value":0.85639947,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"38","issue":"2","first_page":"561","last_page":"571"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10727","display_name":"Ultrasound Imaging and Elastography","score":0.9836999773979187,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4517093598842621},{"id":"https://openalex.org/keywords/saturation","display_name":"Saturation (graph theory)","score":0.4372250437736511},{"id":"https://openalex.org/keywords/fluence","display_name":"Fluence","score":0.43380415439605713},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.413800984621048},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.37292996048927307},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.29530853033065796},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.24872660636901855},{"id":"https://openalex.org/keywords/laser","display_name":"Laser","score":0.14082294702529907},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.1375381052494049},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.11431625485420227}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4517093598842621},{"id":"https://openalex.org/C9930424","wikidata":"https://www.wikidata.org/wiki/Q7426587","display_name":"Saturation (graph theory)","level":2,"score":0.4372250437736511},{"id":"https://openalex.org/C22078206","wikidata":"https://www.wikidata.org/wiki/Q1418023","display_name":"Fluence","level":3,"score":0.43380415439605713},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.413800984621048},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.37292996048927307},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.29530853033065796},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.24872660636901855},{"id":"https://openalex.org/C520434653","wikidata":"https://www.wikidata.org/wiki/Q38867","display_name":"Laser","level":2,"score":0.14082294702529907},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.1375381052494049},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.11431625485420227}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006499","descriptor_name":"Hepatic Artery","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006499","descriptor_name":"Hepatic Artery","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006499","descriptor_name":"Hepatic Artery","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020342","descriptor_name":"Finite Element Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020342","descriptor_name":"Finite Element Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020342","descriptor_name":"Finite Element Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061088","descriptor_name":"Photoacoustic Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D061088","descriptor_name":"Photoacoustic Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D061088","descriptor_name":"Photoacoustic Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1109/tmi.2018.2867602","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tmi.2018.2867602","pdf_url":"https://ieeexplore.ieee.org/ielx7/42/8632831/08458163.pdf","source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:30207951","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30207951","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null},{"id":"pmh:002988107","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1109/tmi.2018.2867602","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da USP (Biblioteca Digital da Produ\u00e7\u00e3o Intelectual)","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:pubmedcentral.nih.gov:6445252","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6445252","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Med Imaging","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1109/tmi.2018.2867602","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tmi.2018.2867602","pdf_url":"https://ieeexplore.ieee.org/ielx7/42/8632831/08458163.pdf","source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G111615301","display_name":null,"funder_award_id":"P30 CA-016672","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G1207441742","display_name":null,"funder_award_id":"P30CA016672","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1310324363","display_name":null,"funder_award_id":"2016/22720-3","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G2378704884","display_name":null,"funder_award_id":"CA 016672","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G291452731","display_name":"Imaging-based quantitative analysis of vascular perfusion and tissue oxygenation to improve therapy of hepatocellular carcinoma","funder_award_id":"RP160229","funder_id":"https://openalex.org/F4320308129","funder_display_name":"Cancer Prevention and Research Institute of Texas"},{"id":"https://openalex.org/G4276892241","display_name":null,"funder_award_id":"P30CA016672","funder_id":"https://openalex.org/F4320308129","funder_display_name":"Cancer Prevention and Research Institute of Texas"},{"id":"https://openalex.org/G4961656942","display_name":null,"funder_award_id":"S10 OD010403","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5805939586","display_name":null,"funder_award_id":"S10 OD019946","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G788993117","display_name":null,"funder_award_id":"CA016672","funder_id":"https://openalex.org/F4320308129","funder_display_name":"Cancer Prevention and Research Institute of Texas"}],"funders":[{"id":"https://openalex.org/F4320308129","display_name":"Cancer Prevention and Research Institute of Texas","ror":"https://ror.org/0003xa228"},{"id":"https://openalex.org/F4320320997","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","ror":"https://ror.org/02ddkpn78"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2889735150.pdf","grobid_xml":"https://content.openalex.org/works/W2889735150.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W107831540","https://openalex.org/W576893836","https://openalex.org/W1485692275","https://openalex.org/W1527004007","https://openalex.org/W1963704146","https://openalex.org/W1964423256","https://openalex.org/W1969900212","https://openalex.org/W1976292567","https://openalex.org/W1981761079","https://openalex.org/W1989541248","https://openalex.org/W1991489579","https://openalex.org/W2002365765","https://openalex.org/W2006535396","https://openalex.org/W2007492138","https://openalex.org/W2013492930","https://openalex.org/W2019076931","https://openalex.org/W2019196396","https://openalex.org/W2030964582","https://openalex.org/W2033978063","https://openalex.org/W2040661938","https://openalex.org/W2043723584","https://openalex.org/W2054178107","https://openalex.org/W2056831021","https://openalex.org/W2059568694","https://openalex.org/W2061135416","https://openalex.org/W2071404056","https://openalex.org/W2072096031","https://openalex.org/W2079024242","https://openalex.org/W2089901886","https://openalex.org/W2091996440","https://openalex.org/W2097683070","https://openalex.org/W2098410051","https://openalex.org/W2102280597","https://openalex.org/W2123894943","https://openalex.org/W2125096092","https://openalex.org/W2125379982","https://openalex.org/W2137492016","https://openalex.org/W2148309086","https://openalex.org/W2151904753","https://openalex.org/W2163462294","https://openalex.org/W2164074898","https://openalex.org/W2165241843","https://openalex.org/W2167916339","https://openalex.org/W2178925703","https://openalex.org/W2397824795","https://openalex.org/W2474740874","https://openalex.org/W2518605307","https://openalex.org/W2730181263","https://openalex.org/W2740135936","https://openalex.org/W4206399495","https://openalex.org/W4230659916","https://openalex.org/W6659127852","https://openalex.org/W6660622358","https://openalex.org/W6674600552","https://openalex.org/W7073955791","https://openalex.org/W7074260767"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W119862936","https://openalex.org/W2000938092","https://openalex.org/W2051487156","https://openalex.org/W2924945250","https://openalex.org/W2072550192","https://openalex.org/W19848063","https://openalex.org/W1983536937"],"abstract_inverted_index":{"As":[0],"photoacoustic":[1],"(PA)":[2],"imaging":[3],"makes":[4],"its":[5],"way":[6],"into":[7],"the":[8,10,111,114,120,128],"clinic,":[9],"accuracy":[11,112],"of":[12,58,82,113,122],"PA-based":[13],"metrics":[14],"becomes":[15],"increasingly":[16],"important.":[17],"To":[18],"address":[19],"this":[20],"need,":[21],"a":[22,53],"method":[23,116],"combining":[24],"finite-element-based":[25],"local":[26],"fluence":[27],"correction":[28],"(LFC)":[29],"with":[30,108,119,141],"signal-to-noise-ratio":[31],"(SNR)":[32],"regularization":[33],"was":[34,62,117],"developed":[35],"and":[36,75,88,98,105],"validated":[37],"to":[38,103,134],"accurately":[39,135],"estimate":[40],"oxygen":[41],"saturation":[42],"(SO":[43],"<sub":[44,71,85,92,138],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[45,72,86,93,139],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">2</sub>":[46,73,87,94,140],")":[47,74],"in":[48,64,76,90],"tissue.":[49],"With":[50],"data":[51],"from":[52,96],"Vevo":[54],"LAZR":[55],"system,":[56],"performance":[57],"our":[59],"LFC":[60,102,115,133],"approach":[61],"assessed":[63],"ex":[65],"vivo":[66,77],"blood":[67],"targets":[68],"(37.6%-99.6%":[69],"SO":[70,84,91,137],"rat":[78],"arteries.":[79],"Estimation":[80],"error":[81],"absolute":[83],"change":[89],"reduced":[95],"10.1%":[97],"6.4%,":[99],"respectively,":[100,107],"without":[101],"2.8%":[104],"2.0%,":[106],"LFC,":[109],"while":[110],"correlated":[118],"number":[121],"wavelengths":[123],"acquired.":[124],"This":[125],"paper":[126],"demonstrates":[127],"need":[129],"for":[130],"an":[131],"SNR-regularized":[132],"quantify":[136],"PA":[142],"imaging.":[143]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":3}],"updated_date":"2026-08-01T09:00:35.917206","created_date":"2025-10-10T00:00:00"}