{"id":"https://openalex.org/W2805090272","doi":"https://doi.org/10.1109/tmi.2018.2841910","title":"Corneal Endothelial Cell Segmentation by Classifier-Driven Merging of Oversegmented Images","display_name":"Corneal Endothelial Cell Segmentation by Classifier-Driven Merging of Oversegmented Images","publication_year":2018,"publication_date":"2018-05-29","ids":{"openalex":"https://openalex.org/W2805090272","doi":"https://doi.org/10.1109/tmi.2018.2841910","mag":"2805090272","pmid":"https://pubmed.ncbi.nlm.nih.gov/29993573"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2018.2841910","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tmi.2018.2841910","pdf_url":"https://ieeexplore.ieee.org/ielx7/42/8478012/08368279.pdf","source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://ieeexplore.ieee.org/ielx7/42/8478012/08368279.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035599050","display_name":"Juan P. Vigueras-Guill\u00e9n","orcid":"https://orcid.org/0000-0002-5676-8217"},"institutions":[{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Juan P. Vigueras-Guillen","raw_affiliation_strings":["Department of Imaging Physics, Delft University of Technology, Delft, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Imaging Physics, Delft University of Technology, Delft, The Netherlands","institution_ids":["https://openalex.org/I98358874"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001356671","display_name":"Eleni\u2010Rosalina Andrinopoulou","orcid":"https://orcid.org/0000-0002-5372-4163"},"institutions":[{"id":"https://openalex.org/I4210130497","display_name":"Combined Ophthalmic Research Rotterdam","ror":"https://ror.org/03cfd9m08","country_code":"NL","type":"nonprofit","lineage":["https://openalex.org/I4210130497"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Eleni-Rosalina Andrinopoulou","raw_affiliation_strings":["Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands","institution_ids":["https://openalex.org/I4210130497"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085148334","display_name":"Angela Engel","orcid":"https://orcid.org/0000-0001-5585-5637"},"institutions":[{"id":"https://openalex.org/I4210130497","display_name":"Combined Ophthalmic Research Rotterdam","ror":"https://ror.org/03cfd9m08","country_code":"NL","type":"nonprofit","lineage":["https://openalex.org/I4210130497"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Angela Engel","raw_affiliation_strings":["Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands","institution_ids":["https://openalex.org/I4210130497"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011555439","display_name":"Hans G. Lemij","orcid":"https://orcid.org/0000-0001-8508-8985"},"institutions":[{"id":"https://openalex.org/I4210120534","display_name":"Rotterdam Eye Hospital","ror":"https://ror.org/02hjc7j46","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210120534"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Hans G. Lemij","raw_affiliation_strings":["Rotterdam Eye Hospital, Rotterdam, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Rotterdam Eye Hospital, Rotterdam, The Netherlands","institution_ids":["https://openalex.org/I4210120534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033340316","display_name":"Jeroen van Rooij","orcid":"https://orcid.org/0000-0001-9754-073X"},"institutions":[{"id":"https://openalex.org/I4210120534","display_name":"Rotterdam Eye Hospital","ror":"https://ror.org/02hjc7j46","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210120534"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jeroen van Rooij","raw_affiliation_strings":["Rotterdam Eye Hospital, Rotterdam, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Rotterdam Eye Hospital, Rotterdam, The Netherlands","institution_ids":["https://openalex.org/I4210120534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016237956","display_name":"Koenraad A. Vermeer","orcid":"https://orcid.org/0000-0002-4038-3945"},"institutions":[{"id":"https://openalex.org/I4210130497","display_name":"Combined Ophthalmic Research Rotterdam","ror":"https://ror.org/03cfd9m08","country_code":"NL","type":"nonprofit","lineage":["https://openalex.org/I4210130497"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Koenraad A. Vermeer","raw_affiliation_strings":["Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands","institution_ids":["https://openalex.org/I4210130497"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065440033","display_name":"Lucas J. van Vliet","orcid":"https://orcid.org/0000-0001-7018-726X"},"institutions":[{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Lucas J. van Vliet","raw_affiliation_strings":["Department of Imaging Physics, Delft University of Technology, Delft, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Imaging Physics, Delft University of Technology, Delft, The Netherlands","institution_ids":["https://openalex.org/I98358874"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5035599050"],"corresponding_institution_ids":["https://openalex.org/I98358874"],"apc_list":null,"apc_paid":null,"fwci":3.0663,"has_fulltext":true,"cited_by_count":38,"citation_normalized_percentile":{"value":0.91871851,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"37","issue":"10","first_page":"2278","last_page":"2289"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10563","display_name":"Corneal surgery and disorders","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10563","display_name":"Corneal surgery and disorders","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10381","display_name":"Ophthalmology and Visual Impairment Studies","score":0.993399977684021,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/corneal-endothelium","display_name":"Corneal endothelium","score":0.7659397125244141},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.6564268469810486},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6509870290756226},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5426166653633118},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5400031805038452},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.522491991519928},{"id":"https://openalex.org/keywords/cornea","display_name":"Cornea","score":0.49240243434906006},{"id":"https://openalex.org/keywords/pleomorphism","display_name":"Pleomorphism (cytology)","score":0.4713525176048279},{"id":"https://openalex.org/keywords/confocal","display_name":"Confocal","score":0.46819931268692017},{"id":"https://openalex.org/keywords/microscopy","display_name":"Microscopy","score":0.46498435735702515},{"id":"https://openalex.org/keywords/confocal-microscopy","display_name":"Confocal microscopy","score":0.45747897028923035},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3947039246559143},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3376670777797699},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.2250824272632599},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.22282201051712036},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.15160229802131653},{"id":"https://openalex.org/keywords/ophthalmology","display_name":"Ophthalmology","score":0.13351285457611084},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.12878453731536865}],"concepts":[{"id":"https://openalex.org/C2775901793","wikidata":"https://www.wikidata.org/wiki/Q1189806","display_name":"Corneal endothelium","level":3,"score":0.7659397125244141},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.6564268469810486},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6509870290756226},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5426166653633118},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5400031805038452},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.522491991519928},{"id":"https://openalex.org/C2776882836","wikidata":"https://www.wikidata.org/wiki/Q168291","display_name":"Cornea","level":2,"score":0.49240243434906006},{"id":"https://openalex.org/C142160229","wikidata":"https://www.wikidata.org/wiki/Q3005740","display_name":"Pleomorphism (cytology)","level":3,"score":0.4713525176048279},{"id":"https://openalex.org/C136009344","wikidata":"https://www.wikidata.org/wiki/Q336201","display_name":"Confocal","level":2,"score":0.46819931268692017},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.46498435735702515},{"id":"https://openalex.org/C2779178360","wikidata":"https://www.wikidata.org/wiki/Q902045","display_name":"Confocal microscopy","level":2,"score":0.45747897028923035},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3947039246559143},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3376670777797699},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2250824272632599},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.22282201051712036},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.15160229802131653},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.13351285457611084},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.12878453731536865},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004728","descriptor_name":"Endothelium, Corneal","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D004728","descriptor_name":"Endothelium, Corneal","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D004728","descriptor_name":"Endothelium, Corneal","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D004728","descriptor_name":"Endothelium, Corneal","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004728","descriptor_name":"Endothelium, Corneal","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004728","descriptor_name":"Endothelium, Corneal","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018613","descriptor_name":"Microscopy, Confocal","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018613","descriptor_name":"Microscopy, Confocal","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018613","descriptor_name":"Microscopy, Confocal","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D060388","descriptor_name":"Support Vector Machine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060388","descriptor_name":"Support Vector Machine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060388","descriptor_name":"Support Vector Machine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1109/tmi.2018.2841910","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tmi.2018.2841910","pdf_url":"https://ieeexplore.ieee.org/ielx7/42/8478012/08368279.pdf","source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:29993573","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29993573","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null},{"id":"pmh:tud:oai:tudelft.nl:uuid:ed324a6b-d219-4f74-bc9e-bc0475ce84a9","is_oa":true,"landing_page_url":"http://resolver.tudelft.nl/uuid:ed324a6b-d219-4f74-bc9e-bc0475ce84a9","pdf_url":"http://resolver.tudelft.nl/uuid:ed324a6b-d219-4f74-bc9e-bc0475ce84a9","source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Transactions on Medical Imaging, 37(10)","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:eur:oai:pure.eur.nl:publications/3a5d5a35-f87c-4b8b-872d-c2b16d8fbae0","is_oa":false,"landing_page_url":"https://pure.eur.nl/en/publications/3a5d5a35-f87c-4b8b-872d-c2b16d8fbae0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Transactions on Medical Imaging, 37(10), 2278 - 2289. Institute of Electrical and Electronics Engineers Inc.","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1109/tmi.2018.2841910","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tmi.2018.2841910","pdf_url":"https://ieeexplore.ieee.org/ielx7/42/8478012/08368279.pdf","source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6000000238418579,"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15"}],"awards":[{"id":"https://openalex.org/G1869279702","display_name":null,"funder_award_id":"842005004","funder_id":"https://openalex.org/F4320321007","funder_display_name":"ZonMw"},{"id":"https://openalex.org/G989490438","display_name":null,"funder_award_id":"842005007","funder_id":"https://openalex.org/F4320321007","funder_display_name":"ZonMw"}],"funders":[{"id":"https://openalex.org/F4320321007","display_name":"ZonMw","ror":"https://ror.org/01yaj9a77"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2805090272.pdf","grobid_xml":"https://content.openalex.org/works/W2805090272.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W772940482","https://openalex.org/W1123185514","https://openalex.org/W1618905105","https://openalex.org/W1658330868","https://openalex.org/W1674518387","https://openalex.org/W1963844593","https://openalex.org/W1978803831","https://openalex.org/W1979854281","https://openalex.org/W1981173496","https://openalex.org/W1986300050","https://openalex.org/W1990416505","https://openalex.org/W1994235406","https://openalex.org/W2009699682","https://openalex.org/W2023941742","https://openalex.org/W2038590892","https://openalex.org/W2039873713","https://openalex.org/W2055029167","https://openalex.org/W2056194685","https://openalex.org/W2064326102","https://openalex.org/W2086843392","https://openalex.org/W2086892210","https://openalex.org/W2115932454","https://openalex.org/W2137311041","https://openalex.org/W2153571188","https://openalex.org/W2417504260","https://openalex.org/W2421619057","https://openalex.org/W2548695521","https://openalex.org/W4230076583","https://openalex.org/W4296086914","https://openalex.org/W6622551206","https://openalex.org/W6637158889","https://openalex.org/W6645345489","https://openalex.org/W6648906691"],"related_works":["https://openalex.org/W2726111829","https://openalex.org/W2294824445","https://openalex.org/W4250585504","https://openalex.org/W2008049857","https://openalex.org/W1978803831","https://openalex.org/W2105513520","https://openalex.org/W2580002495","https://openalex.org/W2056668469","https://openalex.org/W82035557","https://openalex.org/W2055029167"],"abstract_inverted_index":{"Corneal":[0],"endothelium":[1,41,189],"images":[2,47,119],"obtained":[3,75],"by":[4],"in":[5,54,115,151,212],"vivo":[6,116,187],"specular":[7,117],"microscopy":[8,118],"provide":[9],"important":[10],"information":[11,88],"to":[12,37,46,63,92],"assess":[13],"the":[14,18,40,65,81,90,107,134,138,141,197,200],"health":[15],"status":[16],"of":[17,21,73,89,114,140,199],"cornea.":[19],"Estimation":[20],"clinical":[22],"parameters,":[23],"such":[24],"as":[25],"cell":[26,33,55],"density,":[27],"polymegethism,":[28],"and":[29,86,94,127,154,179,183,190,210,221],"pleomorphism,":[30,216],"requires":[31],"accurate":[32],"segmentation.":[34],"State-of-the-art":[35],"techniques":[36],"automatically":[38],"segment":[39,64],"are":[42],"error-prone":[43],"when":[44],"applied":[45],"with":[48,68,196],"low":[49],"contrast":[50],"and/or":[51],"large":[52],"variation":[53],"size.":[56],"Here,":[57],"we":[58,204],"propose":[59],"an":[60,69],"automatic":[61,108],"method":[62,83],"endothelium.":[66],"Starting":[67],"oversegmented":[70],"image":[71],"comprised":[72],"superpixels":[74,91],"from":[76,171],"a":[77,99,111,146,155,218],"stochastic":[78],"watershed":[79],"segmentation,":[80],"proposed":[82],"uses":[84],"intensity":[85],"shape":[87],"identify":[93],"merge":[95],"those":[96],"that":[97],"constitute":[98],"cell,":[100],"using":[101],"support":[102],"vector":[103],"machines.":[104],"We":[105,131],"evaluated":[106,133,165],"segmentation":[109],"on":[110,166],"data":[112,169,201],"set":[113],"(Topcon":[120],"SP-1P),":[121],"obtaining":[122,145],"95.8%":[123],"correctly":[124],"merged":[125],"cells":[126],"2.0%":[128],"undersegmented":[129],"cells.":[130],"also":[132,164],"parameter":[135,161],"estimation":[136,162],"against":[137],"results":[139],"vendor's":[142],"built-in":[143],"software,":[144],"statistically":[147,206],"significant":[148,207],"better":[149,158,208],"precision":[150,211,222],"all":[152,213],"parameters":[153,214],"similar":[156,219],"or":[157],"accuracy.":[159],"The":[160],"was":[163],"three":[167],"other":[168],"sets":[170],"different":[172],"imaging":[173],"modalities":[174],"(confocal":[175],"microscopy,":[176,178],"phase-contrast":[177],"fluorescence":[180],"confocal":[181],"microscopy)":[182],"tissue":[184],"types":[185],"(ex":[186],"corneal":[188],"retinal":[191],"pigment":[192],"epithelium).":[193],"In":[194],"comparison":[195],"estimates":[198],"sets'":[202],"authors,":[203],"achieved":[205],"accuracy":[209,220],"except":[215],"where":[217],"were":[223],"obtained.":[224]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1}],"updated_date":"2026-04-02T15:55:50.835912","created_date":"2025-10-10T00:00:00"}
