{"id":"https://openalex.org/W2952846208","doi":"https://doi.org/10.1109/tmi.2018.2833420","title":"Automated 3-D Neuron Tracing With Precise Branch Erasing and Confidence Controlled Back Tracking","display_name":"Automated 3-D Neuron Tracing With Precise Branch Erasing and Confidence Controlled Back Tracking","publication_year":2018,"publication_date":"2018-05-04","ids":{"openalex":"https://openalex.org/W2952846208","doi":"https://doi.org/10.1109/tmi.2018.2833420","mag":"2952846208","pmid":"https://pubmed.ncbi.nlm.nih.gov/29993997"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2018.2833420","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2018.2833420","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100390236","display_name":"Siqi Liu","orcid":"https://orcid.org/0000-0002-4675-5498"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Siqi Liu","raw_affiliation_strings":["School of Information Technologies, The University of Sydney, Darlington, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"School of Information Technologies, The University of Sydney, Darlington, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038388335","display_name":"Donghao Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Donghao Zhang","raw_affiliation_strings":["School of Information Technologies, The University of Sydney, Darlington, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"School of Information Technologies, The University of Sydney, Darlington, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041567418","display_name":"Yang Song","orcid":"https://orcid.org/0000-0003-1283-1672"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Yang Song","raw_affiliation_strings":["School of Information Technologies, The University of Sydney, Darlington, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"School of Information Technologies, The University of Sydney, Darlington, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hanchuan Peng","orcid":null},"institutions":[{"id":"https://openalex.org/I1314596251","display_name":"Allen Institute for Brain Science","ror":"https://ror.org/00dcv1019","country_code":"US","type":"facility","lineage":["https://openalex.org/I1314596251","https://openalex.org/I4210140341"]},{"id":"https://openalex.org/I4210140341","display_name":"Allen Institute","ror":"https://ror.org/03cpe7c52","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210140341"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hanchuan Peng","raw_affiliation_strings":["Allen Institute for Brain Science, Seattle, WA, USA"],"affiliations":[{"raw_affiliation_string":"Allen Institute for Brain Science, Seattle, WA, USA","institution_ids":["https://openalex.org/I4210140341","https://openalex.org/I1314596251"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076697411","display_name":"Weidong Cai","orcid":"https://orcid.org/0000-0003-3706-8896"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Weidong Cai","raw_affiliation_strings":["School of Information Technologies, The University of Sydney, Darlington, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"School of Information Technologies, The University of Sydney, Darlington, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100390236"],"corresponding_institution_ids":["https://openalex.org/I129604602"],"apc_list":null,"apc_paid":null,"fwci":9.808,"has_fulltext":false,"cited_by_count":72,"citation_normalized_percentile":{"value":0.9821254,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"37","issue":"11","first_page":"2441","last_page":"2452"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9850999712944031,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7370498180389404},{"id":"https://openalex.org/keywords/tracing","display_name":"Tracing","score":0.7353347539901733},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.6660661101341248},{"id":"https://openalex.org/keywords/tracking","display_name":"Tracking (education)","score":0.6407443284988403},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5705664157867432},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.5235435962677002},{"id":"https://openalex.org/keywords/soma","display_name":"Soma","score":0.516152024269104},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.5080075263977051},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.4936893880367279},{"id":"https://openalex.org/keywords/scale","display_name":"Scale (ratio)","score":0.4632139801979065},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.35969752073287964}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7370498180389404},{"id":"https://openalex.org/C138673069","wikidata":"https://www.wikidata.org/wiki/Q322229","display_name":"Tracing","level":2,"score":0.7353347539901733},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.6660661101341248},{"id":"https://openalex.org/C2775936607","wikidata":"https://www.wikidata.org/wiki/Q466845","display_name":"Tracking (education)","level":2,"score":0.6407443284988403},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5705664157867432},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.5235435962677002},{"id":"https://openalex.org/C2779617337","wikidata":"https://www.wikidata.org/wiki/Q842429","display_name":"Soma","level":2,"score":0.516152024269104},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.5080075263977051},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4936893880367279},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.4632139801979065},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.35969752073287964},{"id":"https://openalex.org/C19417346","wikidata":"https://www.wikidata.org/wiki/Q7922","display_name":"Pedagogy","level":1,"score":0.0},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tmi.2018.2833420","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2018.2833420","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:29993997","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29993997","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309327","display_name":"Google","ror":"https://ror.org/00njsd438"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W160351337","https://openalex.org/W1427337929","https://openalex.org/W1508135620","https://openalex.org/W1587637157","https://openalex.org/W1885626623","https://openalex.org/W1969963182","https://openalex.org/W1971167883","https://openalex.org/W1973195069","https://openalex.org/W1981329364","https://openalex.org/W1989396876","https://openalex.org/W1990994043","https://openalex.org/W2010467836","https://openalex.org/W2033865518","https://openalex.org/W2036901575","https://openalex.org/W2060802334","https://openalex.org/W2084972763","https://openalex.org/W2093230218","https://openalex.org/W2097062636","https://openalex.org/W2108436498","https://openalex.org/W2124257654","https://openalex.org/W2129438083","https://openalex.org/W2143560481","https://openalex.org/W2153965609","https://openalex.org/W2156114286","https://openalex.org/W2157408013","https://openalex.org/W2404192493","https://openalex.org/W2421369267","https://openalex.org/W2483701722","https://openalex.org/W2560171554","https://openalex.org/W2571219130","https://openalex.org/W2587001086","https://openalex.org/W2594660495","https://openalex.org/W2600862990"],"related_works":["https://openalex.org/W2101180249","https://openalex.org/W2040277507","https://openalex.org/W3192405764","https://openalex.org/W2323108107","https://openalex.org/W2033189714","https://openalex.org/W2010336780","https://openalex.org/W2506541720","https://openalex.org/W2405027987","https://openalex.org/W4234050681","https://openalex.org/W1522196789"],"abstract_inverted_index":{"The":[0,51,93,119],"automatic":[1,47],"reconstruction":[2],"of":[3,54,109],"single":[4],"neurons":[5],"from":[6,31,63,89,145],"microscopic":[7,33],"images":[8,34,143],"is":[9,58,76],"essential":[10],"to":[11,26,59,68,78],"enable":[12],"large-scale":[13,123],"data-driven":[14],"investigations":[15],"in":[16],"neuron":[17,49],"morphology":[18],"research.":[19],"However,":[20],"few":[21],"previous":[22,99],"methods":[23,100],"were":[24],"able":[25],"generate":[27],"satisfactory":[28],"results":[29],"automatically":[30],"3-D":[32,48],"without":[35],"human":[36],"intervention.":[37],"In":[38],"this":[39],"paper,":[40],"we":[41],"developed":[42],"a":[43,81,105],"new":[44],"algorithm":[45,57,121,140,156],"for":[46,132],"reconstruction.":[50,92],"main":[52],"idea":[53],"the":[55,64,69,90,98,110,114,138,142,147,151,158],"proposed":[56,120,139,155],"iteratively":[60],"track":[61],"backward":[62],"potential":[65],"neuronal":[66],"termini":[67],"soma":[70],"centre.":[71],"An":[72],"online":[73],"confidence":[74,115],"score":[75],"computed":[77],"decide":[79],"if":[80],"tracing":[82],"iteration":[83],"should":[84],"be":[85],"stopped":[86],"and":[87,113,150],"discarded":[88],"final":[91],"performance":[94],"improvements":[95],"comparing":[96],"with":[97],"are":[101],"mainly":[102],"introduced":[103],"by":[104,125],"more":[106],"accurate":[107],"estimation":[108],"traced":[111],"area":[112],"controlled":[116],"back-tracking":[117],"algorithm.":[118],"supports":[122],"batch-processing":[124],"requiring":[126],"only":[127],"one":[128],"user":[129],"specified":[130],"parameter":[131],"background":[133],"segmentation.":[134],"We":[135],"bench":[136],"tested":[137],"on":[141],"obtained":[144],"both":[146],"DIADEM":[148],"challenge":[149],"BigNeuron":[152],"challenge.":[153],"Our":[154],"achieved":[157],"state-of-the-art":[159],"results.":[160]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1}],"updated_date":"2026-03-25T23:56:10.502304","created_date":"2025-10-10T00:00:00"}