{"id":"https://openalex.org/W2774547254","doi":"https://doi.org/10.1109/tmi.2017.2783244","title":"Fast and Accurate Detection of Complex Imaging Genetics Associations Based on Greedy Projected Distance Correlation","display_name":"Fast and Accurate Detection of Complex Imaging Genetics Associations Based on Greedy Projected Distance Correlation","publication_year":2017,"publication_date":"2017-12-13","ids":{"openalex":"https://openalex.org/W2774547254","doi":"https://doi.org/10.1109/tmi.2017.2783244","mag":"2774547254","pmid":"https://pubmed.ncbi.nlm.nih.gov/29990017"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2017.2783244","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2017.2783244","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064967477","display_name":"Jian Fang","orcid":"https://orcid.org/0000-0001-5524-764X"},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jian Fang","raw_affiliation_strings":["Department of Biomedical Engineering, Tulane University, New Orleans, LA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Tulane University, New Orleans, LA, USA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072237935","display_name":"Chao Xu","orcid":"https://orcid.org/0000-0002-3821-6187"},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chao Xu","raw_affiliation_strings":["Department of Biostatistics and Bioinformatics, Tulane University, New Orleans, LA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Bioinformatics, Tulane University, New Orleans, LA, USA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068176773","display_name":"Pascal Zill\u00e9","orcid":"https://orcid.org/0000-0002-8802-1230"},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pascal Zille","raw_affiliation_strings":["Department of Biomedical Engineering, Tulane University, New Orleans, LA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Tulane University, New Orleans, LA, USA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101635490","display_name":"Dongdong Lin","orcid":"https://orcid.org/0000-0001-5645-4798"},"institutions":[{"id":"https://openalex.org/I1334567473","display_name":"Mind Research Network","ror":"https://ror.org/032cjfs80","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1334567473"]},{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dongdong Lin","raw_affiliation_strings":["The Mind Research Networks, The University of New Mexico, Albuquerque, NM, USA"],"affiliations":[{"raw_affiliation_string":"The Mind Research Networks, The University of New Mexico, Albuquerque, NM, USA","institution_ids":["https://openalex.org/I1334567473","https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024194480","display_name":"Hong\u2010Wen Deng","orcid":"https://orcid.org/0000-0002-0387-8818"},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hong-Wen Deng","raw_affiliation_strings":["Department of Biostatistics and Bioinformatics, Tulane University, New Orleans, LA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Bioinformatics, Tulane University, New Orleans, LA, USA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032850756","display_name":"Vince D. Calhoun","orcid":"https://orcid.org/0000-0001-9058-0747"},"institutions":[{"id":"https://openalex.org/I1334567473","display_name":"Mind Research Network","ror":"https://ror.org/032cjfs80","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1334567473"]},{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vince D. Calhoun","raw_affiliation_strings":["The Mind Research Networks, The University of New Mexico, Albuquerque, NM, USA"],"affiliations":[{"raw_affiliation_string":"The Mind Research Networks, The University of New Mexico, Albuquerque, NM, USA","institution_ids":["https://openalex.org/I1334567473","https://openalex.org/I169521973"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100339106","display_name":"Yu\u2010Ping Wang","orcid":"https://orcid.org/0000-0001-9340-5864"},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yu-Ping Wang","raw_affiliation_strings":["Department of Biomedical Engineering, Tulane University, New Orleans, LA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Tulane University, New Orleans, LA, USA","institution_ids":["https://openalex.org/I114832834"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5064967477"],"corresponding_institution_ids":["https://openalex.org/I114832834"],"apc_list":null,"apc_paid":null,"fwci":1.4552,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.82357062,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"37","issue":"4","first_page":"860","last_page":"870"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/correlation","display_name":"Correlation","score":0.7257505655288696},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5996806621551514},{"id":"https://openalex.org/keywords/imaging-genetics","display_name":"Imaging genetics","score":0.5168060064315796},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5132155418395996},{"id":"https://openalex.org/keywords/scalability","display_name":"Scalability","score":0.45233723521232605},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.438210129737854},{"id":"https://openalex.org/keywords/partial-correlation","display_name":"Partial correlation","score":0.43803948163986206},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.39765650033950806},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3206818997859955},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.26314613223075867},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"Neuroimaging","score":0.22559532523155212},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.13013461232185364}],"concepts":[{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.7257505655288696},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5996806621551514},{"id":"https://openalex.org/C18183760","wikidata":"https://www.wikidata.org/wiki/Q6002833","display_name":"Imaging genetics","level":3,"score":0.5168060064315796},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5132155418395996},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.45233723521232605},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.438210129737854},{"id":"https://openalex.org/C64708745","wikidata":"https://www.wikidata.org/wiki/Q2998010","display_name":"Partial correlation","level":3,"score":0.43803948163986206},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.39765650033950806},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3206818997859955},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.26314613223075867},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.22559532523155212},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13013461232185364},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000073216","descriptor_name":"Mental Status and Dementia Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073216","descriptor_name":"Mental Status and Dementia Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073216","descriptor_name":"Mental Status and Dementia Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073216","descriptor_name":"Mental Status and Dementia Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073216","descriptor_name":"Mental Status and Dementia Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073216","descriptor_name":"Mental Status and Dementia Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005821","descriptor_name":"Genetic Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005821","descriptor_name":"Genetic Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005821","descriptor_name":"Genetic Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005821","descriptor_name":"Genetic Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005821","descriptor_name":"Genetic Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005821","descriptor_name":"Genetic Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/tmi.2017.2783244","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2017.2783244","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:29990017","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29990017","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null},{"id":"pmh:oai:europepmc.org:5423232","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6043419","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4407193152","display_name":null,"funder_award_id":"1539067","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":67,"referenced_works":["https://openalex.org/W206906224","https://openalex.org/W1560724230","https://openalex.org/W1620175432","https://openalex.org/W1634632133","https://openalex.org/W1966327575","https://openalex.org/W1967827763","https://openalex.org/W1973891477","https://openalex.org/W1986579353","https://openalex.org/W1987924998","https://openalex.org/W1995245587","https://openalex.org/W1995452282","https://openalex.org/W2002605354","https://openalex.org/W2005821483","https://openalex.org/W2007405802","https://openalex.org/W2008929650","https://openalex.org/W2017518893","https://openalex.org/W2025341678","https://openalex.org/W2027662587","https://openalex.org/W2030561475","https://openalex.org/W2038691711","https://openalex.org/W2040846244","https://openalex.org/W2052680056","https://openalex.org/W2052981010","https://openalex.org/W2061515825","https://openalex.org/W2069088601","https://openalex.org/W2069552222","https://openalex.org/W2079210771","https://openalex.org/W2088126208","https://openalex.org/W2099741732","https://openalex.org/W2104606180","https://openalex.org/W2109046429","https://openalex.org/W2110065044","https://openalex.org/W2111902267","https://openalex.org/W2113506774","https://openalex.org/W2124587329","https://openalex.org/W2126317641","https://openalex.org/W2132622200","https://openalex.org/W2133903921","https://openalex.org/W2135327149","https://openalex.org/W2144902422","https://openalex.org/W2145979309","https://openalex.org/W2147329339","https://openalex.org/W2148702766","https://openalex.org/W2152157708","https://openalex.org/W2156515629","https://openalex.org/W2158200838","https://openalex.org/W2161633633","https://openalex.org/W2163274894","https://openalex.org/W2170917242","https://openalex.org/W2252433728","https://openalex.org/W2263654784","https://openalex.org/W2402346616","https://openalex.org/W2510973425","https://openalex.org/W2552426630","https://openalex.org/W2565638748","https://openalex.org/W2589615506","https://openalex.org/W2963503333","https://openalex.org/W3005621802","https://openalex.org/W3101877337","https://openalex.org/W3106063097","https://openalex.org/W3195149063","https://openalex.org/W6608429153","https://openalex.org/W6675436802","https://openalex.org/W6679614148","https://openalex.org/W6681302627","https://openalex.org/W6681909378","https://openalex.org/W6903518220"],"related_works":["https://openalex.org/W2562018983","https://openalex.org/W1892569393","https://openalex.org/W2095386159","https://openalex.org/W2358202830","https://openalex.org/W2378832745","https://openalex.org/W3111706109","https://openalex.org/W2165707856","https://openalex.org/W2063178317","https://openalex.org/W2014529756","https://openalex.org/W3013810674"],"abstract_inverted_index":{"Recent":[0],"advances":[1],"in":[2],"imaging":[3,75,137],"genetics":[4,76],"produce":[5],"large":[6],"amounts":[7],"of":[8,40,59,136,149],"data":[9,30,176],"including":[10,181],"functional":[11],"MRI":[12],"images,":[13],"single":[14],"nucleotide":[15],"polymorphisms":[16],"(SNPs),":[17],"and":[18,28,38,56,158,184,193],"cognitive":[19],"assessments.":[20],"Understanding":[21],"the":[22,32,51,118,127,163,173],"complex":[23],"interactions":[24],"among":[25,89],"these":[26,60],"heterogeneous":[27],"complementary":[29],"has":[31],"potential":[33],"to":[34,50,70,83,97,172],"help":[35],"with":[36,151,178,201],"diagnosis":[37],"prevention":[39],"mental":[41],"disorders.":[42],"However,":[43],"limited":[44],"efforts":[45],"have":[46],"been":[47],"made":[48],"due":[49],"high":[52],"dimensionality,":[53],"group":[54,100],"structure,":[55],"mixed":[57,91],"type":[58],"data.":[61,77,139],"In":[62,105],"this":[63],"paper":[64],"we":[65,107,168],"present":[66],"a":[67,85,109,146],"novel":[68],"method":[69,171],"detect":[71,98],"conditional":[72,86],"associations":[73,102],"between":[74],"We":[78],"use":[79,94],"projected":[80,120],"distance":[81,121,154],"correlation":[82,122,157,164],"build":[84],"dependency":[87],"graph":[88],"high-dimensional":[90],"data,":[92],"then":[93],"multiple":[95],"testing":[96],"significant":[99,192],"level":[101],"(e.g.,":[103],"ROI-gene).":[104],"addition,":[106],"introduce":[108],"scalable":[110],"algorithm":[111],"based":[112],"on":[113],"orthogonal":[114],"greedy":[115,119],"algorithm,":[116],"yielding":[117],"(G-PDC).":[123],"This":[124],"can":[125],"reduce":[126],"computational":[128],"cost,":[129],"which":[130,197],"is":[131,165,208],"critical":[132],"for":[133],"analyzing":[134],"large-volume":[135],"genomics":[138],"The":[140,187,205],"results":[141,188],"from":[142],"our":[143,170],"simulations":[144],"demonstrate":[145],"higher":[147],"degree":[148],"accuracy":[150],"GPDC":[152],"than":[153],"correlation,":[155,160],"Pearson's":[156],"partial":[159],"especially":[161],"when":[162],"nonlinear.":[166],"Finally,":[167],"apply":[169],"Philadelphia":[174],"Neurodevelopmental":[175],"cohort":[177],"866":[179],"samples":[180],"fMRI":[182],"images":[183],"SNP":[185],"profiles.":[186],"uncover":[189],"several":[190],"statistically":[191],"biologically":[194],"interesting":[195],"interactions,":[196],"are":[198],"further":[199],"validated":[200],"many":[202],"existing":[203],"studies.":[204],"Matlab":[206],"code":[207],"available":[209],"at":[210],"https://sites.google.com/site/jianfang86/gPDC.":[211]},"counts_by_year":[{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":1}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}