{"id":"https://openalex.org/W2532740511","doi":"https://doi.org/10.1109/tmi.2016.2620961","title":"Fast Realistic MRI Simulations Based on Generalized Multi-Pool Exchange Tissue Model","display_name":"Fast Realistic MRI Simulations Based on Generalized Multi-Pool Exchange Tissue Model","publication_year":2016,"publication_date":"2016-10-25","ids":{"openalex":"https://openalex.org/W2532740511","doi":"https://doi.org/10.1109/tmi.2016.2620961","mag":"2532740511","pmid":"https://pubmed.ncbi.nlm.nih.gov/28113746"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2016.2620961","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2016.2620961","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5322984","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039127636","display_name":"Fang Liu","orcid":"https://orcid.org/0000-0001-8032-6681"},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Fang Liu","raw_affiliation_strings":["Department of Radiology, University of Wisconsin at Madison, Madison, WI, USA"],"affiliations":[{"raw_affiliation_string":"Department of Radiology, University of Wisconsin at Madison, Madison, WI, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016172501","display_name":"Julia Velikina","orcid":"https://orcid.org/0000-0002-2058-8601"},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julia V. Velikina","raw_affiliation_strings":["Department of Medical Physics, University of Wisconsin at Madison, Madison, WI, USA"],"affiliations":[{"raw_affiliation_string":"Department of Medical Physics, University of Wisconsin at Madison, Madison, WI, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040863782","display_name":"Walter F. Block","orcid":"https://orcid.org/0000-0002-2262-9972"},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Walter F. Block","raw_affiliation_strings":["Department of Medical Physics and Biomedical Engineering, University of Wisconsin at Madison, Madison, WI, USA"],"affiliations":[{"raw_affiliation_string":"Department of Medical Physics and Biomedical Engineering, University of Wisconsin at Madison, Madison, WI, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103085422","display_name":"Richard Kijowski","orcid":"https://orcid.org/0000-0002-2669-267X"},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Kijowski","raw_affiliation_strings":["Department of Radiology, University of Wisconsin at Madison, Madison, WI, USA"],"affiliations":[{"raw_affiliation_string":"Department of Radiology, University of Wisconsin at Madison, Madison, WI, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000930536","display_name":"Alexey Samsonov","orcid":"https://orcid.org/0000-0003-1966-3034"},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexey A. Samsonov","raw_affiliation_strings":["Department of Radiology, University of Wisconsin at Madison, Madison, WI, USA"],"affiliations":[{"raw_affiliation_string":"Department of Radiology, University of Wisconsin at Madison, Madison, WI, USA","institution_ids":["https://openalex.org/I135310074"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5039127636"],"corresponding_institution_ids":["https://openalex.org/I135310074"],"apc_list":null,"apc_paid":null,"fwci":5.694,"has_fulltext":false,"cited_by_count":114,"citation_normalized_percentile":{"value":0.96145639,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"36","issue":"2","first_page":"527","last_page":"537"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11809","display_name":"Advanced NMR Techniques and Applications","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.8101202249526978},{"id":"https://openalex.org/keywords/voxel","display_name":"Voxel","score":0.6486899852752686},{"id":"https://openalex.org/keywords/computational-science","display_name":"Computational science","score":0.6096682548522949},{"id":"https://openalex.org/keywords/representation","display_name":"Representation (politics)","score":0.4540099501609802},{"id":"https://openalex.org/keywords/extensibility","display_name":"Extensibility","score":0.4283924102783203},{"id":"https://openalex.org/keywords/range","display_name":"Range (aeronautics)","score":0.42024660110473633},{"id":"https://openalex.org/keywords/simulation","display_name":"Simulation","score":0.41848015785217285},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2243865728378296},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.1040160059928894}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.8101202249526978},{"id":"https://openalex.org/C54170458","wikidata":"https://www.wikidata.org/wiki/Q663554","display_name":"Voxel","level":2,"score":0.6486899852752686},{"id":"https://openalex.org/C459310","wikidata":"https://www.wikidata.org/wiki/Q117801","display_name":"Computational science","level":1,"score":0.6096682548522949},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.4540099501609802},{"id":"https://openalex.org/C32833848","wikidata":"https://www.wikidata.org/wiki/Q4115054","display_name":"Extensibility","level":2,"score":0.4283924102783203},{"id":"https://openalex.org/C204323151","wikidata":"https://www.wikidata.org/wiki/Q905424","display_name":"Range (aeronautics)","level":2,"score":0.42024660110473633},{"id":"https://openalex.org/C44154836","wikidata":"https://www.wikidata.org/wiki/Q45045","display_name":"Simulation","level":1,"score":0.41848015785217285},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2243865728378296},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.1040160059928894},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1109/tmi.2016.2620961","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2016.2620961","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:28113746","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28113746","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:5322984","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5322984","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Med Imaging","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:5322984","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5322984","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Med Imaging","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation","score":0.800000011920929}],"awards":[{"id":"https://openalex.org/G5941431899","display_name":null,"funder_award_id":"R21EB018483","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G6608879333","display_name":null,"funder_award_id":"R01AR068373","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G988310440","display_name":null,"funder_award_id":"R01NS065034","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W1481312851","https://openalex.org/W1500124743","https://openalex.org/W1855236261","https://openalex.org/W1871922075","https://openalex.org/W1929489224","https://openalex.org/W1964997677","https://openalex.org/W1968006940","https://openalex.org/W1979646717","https://openalex.org/W1992219232","https://openalex.org/W1995773861","https://openalex.org/W1999977619","https://openalex.org/W2015122748","https://openalex.org/W2022514814","https://openalex.org/W2023445344","https://openalex.org/W2026083078","https://openalex.org/W2034392349","https://openalex.org/W2034686094","https://openalex.org/W2035640700","https://openalex.org/W2039886992","https://openalex.org/W2039981583","https://openalex.org/W2040111121","https://openalex.org/W2044930346","https://openalex.org/W2045527031","https://openalex.org/W2050983595","https://openalex.org/W2053999722","https://openalex.org/W2054190705","https://openalex.org/W2055557864","https://openalex.org/W2055958409","https://openalex.org/W2057756493","https://openalex.org/W2062309659","https://openalex.org/W2065699969","https://openalex.org/W2072418533","https://openalex.org/W2072626310","https://openalex.org/W2074036832","https://openalex.org/W2076378544","https://openalex.org/W2080737598","https://openalex.org/W2081774390","https://openalex.org/W2083092827","https://openalex.org/W2086279301","https://openalex.org/W2088764776","https://openalex.org/W2093864226","https://openalex.org/W2100539437","https://openalex.org/W2107915383","https://openalex.org/W2117245594","https://openalex.org/W2123549954","https://openalex.org/W2130735928","https://openalex.org/W2140804420","https://openalex.org/W2146292423","https://openalex.org/W2146730623","https://openalex.org/W2164465395","https://openalex.org/W2165648888","https://openalex.org/W2167233877","https://openalex.org/W2260251644","https://openalex.org/W2324568579","https://openalex.org/W4249760698"],"related_works":["https://openalex.org/W2401862472","https://openalex.org/W2364420803","https://openalex.org/W2368425793","https://openalex.org/W4253241429","https://openalex.org/W2036340253","https://openalex.org/W2049581502","https://openalex.org/W1984116007","https://openalex.org/W2372886617","https://openalex.org/W3157317564","https://openalex.org/W2351444320"],"abstract_inverted_index":{"We":[0],"present":[1],"MRiLab,":[2],"a":[3,13,18,43,57,86,139,173],"new":[4,135,188],"comprehensive":[5],"simulator":[6,136],"for":[7,101,178],"large-scale":[8],"realistic":[9,26],"MRI":[10,34,47,52,125,181,189],"simulations":[11],"on":[12,56,118],"regular":[14],"PC":[15],"equipped":[16],"with":[17,29,76],"modern":[19],"graphical":[20],"processing":[21],"unit":[22],"(GPU).":[23],"MRiLab":[24,69,183],"combines":[25],"tissue":[27,64,74,107,154,197],"modeling":[28],"numerical":[30],"virtualization":[31],"of":[32,42,46,63,88,103,133,142,150,153,187],"an":[33],"system":[35,87],"and":[36,80,122,146,199],"scanning":[37],"experiment":[38],"to":[39,129,137,194],"enable":[40],"assessment":[41],"broad":[44],"range":[45],"approaches":[48],"including":[49],"advanced":[50],"quantitative":[51],"methods":[53],"inferring":[54],"microstructure":[55,65],"sub-voxel":[58],"level.":[59],"A":[60],"flexible":[61],"representation":[62],"is":[66,113],"achieved":[67],"in":[68,94,109,157,166],"by":[70],"employing":[71],"the":[72,104,131,134,185],"generalized":[73],"model":[75],"multiple":[77],"exchanging":[78],"water":[79],"macromolecular":[81],"proton":[82,90],"pools":[83],"rather":[84],"than":[85],"independent":[89],"isochromats":[91],"typically":[92],"used":[93],"previous":[95,158],"simulators.":[96,159],"The":[97],"computational":[98,167],"power":[99],"needed":[100],"simulation":[102],"biologically":[105],"relevant":[106],"models":[108],"large":[110],"3D":[111],"objects":[112],"gained":[114],"using":[115],"parallelized":[116],"execution":[117,161],"GPU.":[119],"Three":[120],"simulated":[121],"one":[123],"actual":[124],"experiments":[126],"were":[127],"performed":[128],"demonstrate":[130,147],"ability":[132],"accommodate":[138],"wide":[140],"variety":[141],"voxel":[143],"composition":[144,198],"scenarios":[145],"detrimental":[148],"effects":[149],"simplified":[151],"treatment":[152],"micro-organization":[155],"adapted":[156],"GPU":[160],"allowed":[162],"\u223c":[163],"200\u00d7":[164],"improvement":[165],"speed":[168],"over":[169],"standard":[170],"CPU.":[171],"As":[172],"cross-platform,":[174],"open-source,":[175],"extensible":[176],"environment":[177],"customizing":[179],"virtual":[180],"experiments,":[182],"streamlines":[184],"development":[186],"methods,":[190],"especially":[191],"those":[192],"aiming":[193],"infer":[195],"quantitatively":[196],"microstructure.":[200]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":22},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":17},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":4}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}