{"id":"https://openalex.org/W2285032621","doi":"https://doi.org/10.1109/tmi.2015.2478742","title":"Gradient-Based Quantitative Image Reconstruction in Ultrasound-Modulated Optical Tomography: First Harmonic Measurement Type in a Linearised Diffusion Formulation","display_name":"Gradient-Based Quantitative Image Reconstruction in Ultrasound-Modulated Optical Tomography: First Harmonic Measurement Type in a Linearised Diffusion Formulation","publication_year":2015,"publication_date":"2015-09-14","ids":{"openalex":"https://openalex.org/W2285032621","doi":"https://doi.org/10.1109/tmi.2015.2478742","mag":"2285032621","pmid":"https://pubmed.ncbi.nlm.nih.gov/26390449"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2015.2478742","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tmi.2015.2478742","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["arxiv","crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1109/tmi.2015.2478742","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Samuel Powell","orcid":null},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Samuel Powell","raw_affiliation_strings":["Department of Computer Science, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Simon R. Arridge","orcid":null},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Simon R. Arridge","raw_affiliation_strings":["Department of Computer Science, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":null,"display_name":"Terence S. Leung","orcid":null},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Terence S. Leung","raw_affiliation_strings":["Department of Medical Physics and Biomedical Engineering, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Physics and Biomedical Engineering, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I45129253"],"apc_list":{"value":2645,"currency":"USD","value_usd":2645},"apc_paid":{"value":2645,"currency":"USD","value_usd":2645},"fwci":0.4973,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.69986649,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"35","issue":"2","first_page":"456","last_page":"467"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.7336999773979187,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.7336999773979187,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.20020000636577606,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11569","display_name":"Optical Coherence Tomography Applications","score":0.02160000056028366,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/optical-tomography","display_name":"Optical tomography","score":0.6036999821662903},{"id":"https://openalex.org/keywords/raster-scan","display_name":"Raster scan","score":0.5476999878883362},{"id":"https://openalex.org/keywords/iterative-reconstruction","display_name":"Iterative reconstruction","score":0.5120999813079834},{"id":"https://openalex.org/keywords/diffuse-optical-imaging","display_name":"Diffuse optical imaging","score":0.4758000075817108},{"id":"https://openalex.org/keywords/image-resolution","display_name":"Image resolution","score":0.4593999981880188},{"id":"https://openalex.org/keywords/sensitivity","display_name":"Sensitivity (control systems)","score":0.454800009727478},{"id":"https://openalex.org/keywords/gaussian","display_name":"Gaussian","score":0.42980000376701355},{"id":"https://openalex.org/keywords/raster-graphics","display_name":"Raster graphics","score":0.4203000068664551},{"id":"https://openalex.org/keywords/boundary","display_name":"Boundary (topology)","score":0.39910000562667847},{"id":"https://openalex.org/keywords/convolution","display_name":"Convolution (computer science)","score":0.39890000224113464}],"concepts":[{"id":"https://openalex.org/C2777413408","wikidata":"https://www.wikidata.org/wiki/Q1968843","display_name":"Optical tomography","level":3,"score":0.6036999821662903},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.5598000288009644},{"id":"https://openalex.org/C145406643","wikidata":"https://www.wikidata.org/wiki/Q2641959","display_name":"Raster scan","level":2,"score":0.5476999878883362},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.5120999813079834},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.49300000071525574},{"id":"https://openalex.org/C145417883","wikidata":"https://www.wikidata.org/wiki/Q5275421","display_name":"Diffuse optical imaging","level":3,"score":0.4758000075817108},{"id":"https://openalex.org/C205372480","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"Image resolution","level":2,"score":0.4593999981880188},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.454800009727478},{"id":"https://openalex.org/C163716315","wikidata":"https://www.wikidata.org/wiki/Q901177","display_name":"Gaussian","level":2,"score":0.42980000376701355},{"id":"https://openalex.org/C181844469","wikidata":"https://www.wikidata.org/wiki/Q182270","display_name":"Raster graphics","level":2,"score":0.4203000068664551},{"id":"https://openalex.org/C62354387","wikidata":"https://www.wikidata.org/wiki/Q875399","display_name":"Boundary (topology)","level":2,"score":0.39910000562667847},{"id":"https://openalex.org/C45347329","wikidata":"https://www.wikidata.org/wiki/Q5166604","display_name":"Convolution (computer science)","level":3,"score":0.39890000224113464},{"id":"https://openalex.org/C175231954","wikidata":"https://www.wikidata.org/wiki/Q1942321","display_name":"Optical transfer function","level":2,"score":0.37139999866485596},{"id":"https://openalex.org/C123079801","wikidata":"https://www.wikidata.org/wiki/Q750240","display_name":"Modulation (music)","level":2,"score":0.36880001425743103},{"id":"https://openalex.org/C191486275","wikidata":"https://www.wikidata.org/wiki/Q210028","display_name":"Scattering","level":2,"score":0.365200012922287},{"id":"https://openalex.org/C127934551","wikidata":"https://www.wikidata.org/wiki/Q1148098","display_name":"Harmonic","level":2,"score":0.34599998593330383},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.34060001373291016},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.3361999988555908},{"id":"https://openalex.org/C100921725","wikidata":"https://www.wikidata.org/wiki/Q1650811","display_name":"Spatial frequency","level":2,"score":0.3319000005722046},{"id":"https://openalex.org/C19118579","wikidata":"https://www.wikidata.org/wiki/Q786423","display_name":"Frequency domain","level":2,"score":0.3294999897480011},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.32739999890327454},{"id":"https://openalex.org/C55020928","wikidata":"https://www.wikidata.org/wiki/Q3813865","display_name":"Image quality","level":3,"score":0.326200008392334},{"id":"https://openalex.org/C182310444","wikidata":"https://www.wikidata.org/wiki/Q1332643","display_name":"Boundary value problem","level":2,"score":0.3253999948501587},{"id":"https://openalex.org/C103824480","wikidata":"https://www.wikidata.org/wiki/Q185889","display_name":"Time domain","level":2,"score":0.32350000739097595},{"id":"https://openalex.org/C132771110","wikidata":"https://www.wikidata.org/wiki/Q506922","display_name":"Adaptive optics","level":2,"score":0.31529998779296875},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.30820000171661377},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.3057999908924103},{"id":"https://openalex.org/C18762648","wikidata":"https://www.wikidata.org/wiki/Q42213","display_name":"Work (physics)","level":2,"score":0.295199990272522},{"id":"https://openalex.org/C163716698","wikidata":"https://www.wikidata.org/wiki/Q841267","display_name":"Tomography","level":2,"score":0.29350000619888306},{"id":"https://openalex.org/C143724316","wikidata":"https://www.wikidata.org/wiki/Q312468","display_name":"Series (stratigraphy)","level":2,"score":0.28870001435279846},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.2865000069141388},{"id":"https://openalex.org/C115635565","wikidata":"https://www.wikidata.org/wiki/Q860900","display_name":"Digital image correlation","level":2,"score":0.28110000491142273},{"id":"https://openalex.org/C138268822","wikidata":"https://www.wikidata.org/wiki/Q1051925","display_name":"Resolution (logic)","level":2,"score":0.2809000015258789},{"id":"https://openalex.org/C69179731","wikidata":"https://www.wikidata.org/wiki/Q510427","display_name":"Point spread function","level":2,"score":0.2800000011920929},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.27090001106262207},{"id":"https://openalex.org/C9417928","wikidata":"https://www.wikidata.org/wiki/Q1070689","display_name":"Image processing","level":3,"score":0.2689000070095062},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2687999904155731},{"id":"https://openalex.org/C119666444","wikidata":"https://www.wikidata.org/wiki/Q5977280","display_name":"Temporal resolution","level":2,"score":0.260699987411499},{"id":"https://openalex.org/C61326573","wikidata":"https://www.wikidata.org/wiki/Q1496376","display_name":"Gaussian process","level":3,"score":0.2572999894618988},{"id":"https://openalex.org/C120456961","wikidata":"https://www.wikidata.org/wiki/Q210028","display_name":"Light scattering","level":3,"score":0.2533000111579895}],"mesh":[{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020342","descriptor_name":"Finite Element Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020342","descriptor_name":"Finite Element Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020342","descriptor_name":"Finite Element Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1109/tmi.2015.2478742","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tmi.2015.2478742","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:26390449","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26390449","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":"Journal Article"},{"id":"pmh:oai:arXiv.org:1409.2035","is_oa":true,"landing_page_url":"http://arxiv.org/abs/1409.2035","pdf_url":"https://arxiv.org/pdf/1409.2035","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"pmh:oai:nottingham-repository.worktribe.com:3791700","is_oa":true,"landing_page_url":"https://nottingham-repository.worktribe.com/output/3791700","pdf_url":null,"source":{"id":"https://openalex.org/S4306402483","display_name":"Repository@Nottingham (University of Nottingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I142263535","host_organization_name":"University of Nottingham","host_organization_lineage":["https://openalex.org/I142263535"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1109/tmi.2015.2478742","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tmi.2015.2478742","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1342968423","display_name":null,"funder_award_id":"EP/G005036/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G2519880784","display_name":"Tomographic imaging of flow and chromophore concentrations in biological tissue","funder_award_id":"EP/N032055/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G7909925325","display_name":null,"funder_award_id":"EP/N032055/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8266975289","display_name":"A hybrid optical and ultrasound system to measure localized oxygenation, blood flow and oxygen consumption in the human body","funder_award_id":"EP/G005036/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W311663650","https://openalex.org/W1966152886","https://openalex.org/W1971997342","https://openalex.org/W1975915764","https://openalex.org/W1978323846","https://openalex.org/W1986682629","https://openalex.org/W1989038201","https://openalex.org/W1989541248","https://openalex.org/W1994443713","https://openalex.org/W2004043663","https://openalex.org/W2007135667","https://openalex.org/W2007318338","https://openalex.org/W2012755947","https://openalex.org/W2016170197","https://openalex.org/W2019463947","https://openalex.org/W2020784063","https://openalex.org/W2033106066","https://openalex.org/W2037472202","https://openalex.org/W2038725456","https://openalex.org/W2045255039","https://openalex.org/W2046192310","https://openalex.org/W2052998383","https://openalex.org/W2053358046","https://openalex.org/W2053851915","https://openalex.org/W2063293760","https://openalex.org/W2064317969","https://openalex.org/W2069009977","https://openalex.org/W2069440048","https://openalex.org/W2074939412","https://openalex.org/W2075463757","https://openalex.org/W2075801641","https://openalex.org/W2081589438","https://openalex.org/W2082495127","https://openalex.org/W2084242407","https://openalex.org/W2085564184","https://openalex.org/W2087257456","https://openalex.org/W2091725182","https://openalex.org/W2101218782","https://openalex.org/W2101516194","https://openalex.org/W2102994171","https://openalex.org/W2106444568","https://openalex.org/W2113542224","https://openalex.org/W2125915704","https://openalex.org/W2133404950","https://openalex.org/W2142393916","https://openalex.org/W2143163067","https://openalex.org/W2143465387","https://openalex.org/W2148309086","https://openalex.org/W2151904753","https://openalex.org/W2154521780","https://openalex.org/W2157048271","https://openalex.org/W2157946377","https://openalex.org/W2164506952","https://openalex.org/W2164668388","https://openalex.org/W2964205751","https://openalex.org/W4293775970","https://openalex.org/W6649808808"],"related_works":[],"abstract_inverted_index":{"Ultrasound-modulated":[0],"optical":[1,26,87,129],"tomography":[2],"is":[3,170],"an":[4,38,100],"emerging":[5],"biomedical":[6],"imaging":[7],"modality":[8,82],"which":[9,50,76,107],"uses":[10],"the":[11,23,52,58,68,74,78,81,86,97,109,147,151,161,164,168],"spatially":[12],"localised":[13],"acoustically-driven":[14],"modulation":[15],"of":[16,22,28,40,60,73,80,89,99,115,128,150,156,163],"coherent":[17],"light":[18],"as":[19],"a":[20,46,61,116],"probe":[21],"structure":[24],"and":[25,66,112,131,135,145],"properties":[27],"biological":[29],"tissues.":[30],"In":[31],"this":[32],"work":[33,124],"we":[34,92],"begin":[35],"by":[36,125],"providing":[37],"overview":[39],"forward":[41],"modelling":[42],"methods,":[43],"before":[44],"deriving":[45],"linearised":[47],"diffusion-style":[48],"model":[49,75],"calculates":[51],"first-harmonic":[53],"modulated":[54],"flux":[55],"measured":[56],"on":[57],"boundary":[59],"given":[62],"domain.":[63],"We":[64,121],"derive":[65],"examine":[67],"correlation":[69],"measurement":[70],"density":[71],"functions":[72,95],"describe":[77],"sensitivity":[79],"to":[83,153,172],"perturbations":[84],"in":[85,96,133],"parameters":[88,152],"interest.":[90],"Finally,":[91],"employ":[93],"said":[94],"development":[98],"adjoint-assisted":[101],"gradient":[102],"based":[103],"image":[104],"reconstruction":[105],"method,":[106],"ameliorates":[108],"computational":[110],"burden":[111],"memory":[113],"requirements":[114],"traditional":[117],"Newton-based":[118],"optimisation":[119],"approach.":[120],"validate":[122],"our":[123],"performing":[126],"reconstructions":[127],"absorption":[130],"scattering":[132],"two-":[134],"three-dimensions":[136],"using":[137],"simulated":[138],"measurements":[139],"with":[140],"1%":[141],"proportional":[142],"Gaussian":[143],"noise,":[144],"demonstrate":[146],"successful":[148],"recovery":[149],"within":[154],"\u00b15%":[155],"their":[157],"true":[158],"values":[159],"when":[160],"resolution":[162],"ultrasound":[165],"raster":[166],"probing":[167],"domain":[169],"sufficient":[171],"delineate":[173],"perturbing":[174],"inclusions.":[175]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2017,"cited_by_count":2}],"updated_date":"2026-08-27T14:10:00.468798","created_date":"2016-06-24T00:00:00"}