{"id":"https://openalex.org/W2068565697","doi":"https://doi.org/10.1109/tmi.2012.2220153","title":"Combining Boundary-Based Methods With Tensor-Based Morphometry in the Measurement of Longitudinal Brain Change","display_name":"Combining Boundary-Based Methods With Tensor-Based Morphometry in the Measurement of Longitudinal Brain Change","publication_year":2012,"publication_date":"2012-09-21","ids":{"openalex":"https://openalex.org/W2068565697","doi":"https://doi.org/10.1109/tmi.2012.2220153","mag":"2068565697","pmid":"https://pubmed.ncbi.nlm.nih.gov/23014714"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2012.2220153","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2012.2220153","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3775845","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001221823","display_name":"Evan Fletcher","orcid":"https://orcid.org/0000-0002-9761-3131"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Evan Fletcher","raw_affiliation_strings":["IDeA Laboratory, Department of Neurology, University of California-Davis, Davis, CA 95618, USA. evanfletcher@gmail.com","Department of Neurology University of California Davis Davis CA USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IDeA Laboratory, Department of Neurology, University of California-Davis, Davis, CA 95618, USA. evanfletcher@gmail.com","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Department of Neurology University of California Davis Davis CA USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008640397","display_name":"Alexander Knaack","orcid":"https://orcid.org/0000-0002-5231-3637"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]},{"id":"https://openalex.org/I98947143","display_name":"California State Polytechnic University","ror":"https://ror.org/05by5hm18","country_code":"US","type":"education","lineage":["https://openalex.org/I98947143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander Knaack","raw_affiliation_strings":["Department of Computer Science, California State Polytechnic University, Pomona, CA, USA","Department of Neurology University of California Davis Davis CA USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, California State Polytechnic University, Pomona, CA, USA","institution_ids":["https://openalex.org/I98947143"]},{"raw_affiliation_string":"Department of Neurology University of California Davis Davis CA USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027576519","display_name":"Baljeet Singh","orcid":"https://orcid.org/0000-0002-8029-8577"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Baljeet Singh","raw_affiliation_strings":["University of California Davis, Davis, CA, US","Department of Neurology University of California Davis Davis CA USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Davis, Davis, CA, US","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Department of Neurology University of California Davis Davis CA USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017059217","display_name":"Evan Lloyd","orcid":null},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Evan Lloyd","raw_affiliation_strings":["Department of Computer Science, University of California-Los Angeles, Los Angeles, CA, USA","Department of Neurology University of California Davis Davis CA USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of California-Los Angeles, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Department of Neurology University of California Davis Davis CA USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072643068","display_name":"Evan Wu","orcid":null},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Evan Wu","raw_affiliation_strings":["Department of Neurology, IDeA Laboratory, Davis, CA, USA","Department of Neurology University of California Davis Davis CA USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, IDeA Laboratory, Davis, CA, USA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Department of Neurology University of California Davis Davis CA USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054637868","display_name":"Owen Carmichael","orcid":"https://orcid.org/0000-0002-0576-0047"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Owen Carmichael","raw_affiliation_strings":["Department of Neurology, IDeA Laboratory, Davis, CA, USA","Department of Neurology University of California Davis Davis CA USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, IDeA Laboratory, Davis, CA, USA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Department of Neurology University of California Davis Davis CA USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113986658","display_name":"Charles DeCarli","orcid":null},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles DeCarli","raw_affiliation_strings":["Department of Neurology, IDeA Laboratory, Davis, CA, USA","Department of Neurology University of California Davis Davis CA USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, IDeA Laboratory, Davis, CA, USA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Department of Neurology University of California Davis Davis CA USA","institution_ids":["https://openalex.org/I84218800"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.5383,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.828896,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"32","issue":"2","first_page":"223","last_page":"236"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.984000027179718,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9829000234603882,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.7658771276473999},{"id":"https://openalex.org/keywords/sensitivity","display_name":"Sensitivity (control systems)","score":0.6163963675498962},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5378161668777466},{"id":"https://openalex.org/keywords/inverse-problem","display_name":"Inverse problem","score":0.4958866536617279},{"id":"https://openalex.org/keywords/consistency","display_name":"Consistency (knowledge bases)","score":0.48225122690200806},{"id":"https://openalex.org/keywords/inverse","display_name":"Inverse","score":0.46367570757865906},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4533407986164093},{"id":"https://openalex.org/keywords/change-detection","display_name":"Change detection","score":0.43537795543670654},{"id":"https://openalex.org/keywords/tensor","display_name":"Tensor (intrinsic definition)","score":0.42390304803848267},{"id":"https://openalex.org/keywords/boundary","display_name":"Boundary (topology)","score":0.4236159026622772},{"id":"https://openalex.org/keywords/neurophysiology","display_name":"Neurophysiology","score":0.4234265983104706},{"id":"https://openalex.org/keywords/term","display_name":"Term (time)","score":0.4164086580276489},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.38197755813598633},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3735820949077606},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.36635416746139526},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.1593286395072937},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.1493816375732422},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.11490777134895325}],"concepts":[{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.7658771276473999},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.6163963675498962},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5378161668777466},{"id":"https://openalex.org/C135252773","wikidata":"https://www.wikidata.org/wiki/Q1567213","display_name":"Inverse problem","level":2,"score":0.4958866536617279},{"id":"https://openalex.org/C2776436953","wikidata":"https://www.wikidata.org/wiki/Q5163215","display_name":"Consistency (knowledge bases)","level":2,"score":0.48225122690200806},{"id":"https://openalex.org/C207467116","wikidata":"https://www.wikidata.org/wiki/Q4385666","display_name":"Inverse","level":2,"score":0.46367570757865906},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4533407986164093},{"id":"https://openalex.org/C203595873","wikidata":"https://www.wikidata.org/wiki/Q25389927","display_name":"Change detection","level":2,"score":0.43537795543670654},{"id":"https://openalex.org/C155281189","wikidata":"https://www.wikidata.org/wiki/Q3518150","display_name":"Tensor (intrinsic definition)","level":2,"score":0.42390304803848267},{"id":"https://openalex.org/C62354387","wikidata":"https://www.wikidata.org/wiki/Q875399","display_name":"Boundary (topology)","level":2,"score":0.4236159026622772},{"id":"https://openalex.org/C152478114","wikidata":"https://www.wikidata.org/wiki/Q660910","display_name":"Neurophysiology","level":2,"score":0.4234265983104706},{"id":"https://openalex.org/C61797465","wikidata":"https://www.wikidata.org/wiki/Q1188986","display_name":"Term (time)","level":2,"score":0.4164086580276489},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.38197755813598633},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3735820949077606},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.36635416746139526},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.1593286395072937},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1493816375732422},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.11490777134895325},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013382","descriptor_name":"Subtraction Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013382","descriptor_name":"Subtraction Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013382","descriptor_name":"Subtraction Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D038524","descriptor_name":"Diffusion Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D038524","descriptor_name":"Diffusion Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D038524","descriptor_name":"Diffusion Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1109/tmi.2012.2220153","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2012.2220153","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:23014714","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23014714","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null},{"id":"pmh:oai:europepmc.org:2895265","is_oa":false,"landing_page_url":"http://europepmc.org/articles/PMC3775845","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3775845","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3775845","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Med Imaging","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3775845","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3775845","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Med Imaging","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/16","score":0.44999998807907104,"display_name":"Peace, Justice and strong institutions"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W1518961746","https://openalex.org/W1536265295","https://openalex.org/W1549545612","https://openalex.org/W1719894433","https://openalex.org/W1888801276","https://openalex.org/W1965537927","https://openalex.org/W1972099553","https://openalex.org/W1973637437","https://openalex.org/W1977832043","https://openalex.org/W1982361270","https://openalex.org/W2001666669","https://openalex.org/W2004293194","https://openalex.org/W2006907540","https://openalex.org/W2008152557","https://openalex.org/W2009463061","https://openalex.org/W2015936728","https://openalex.org/W2029214174","https://openalex.org/W2041398617","https://openalex.org/W2063859734","https://openalex.org/W2069456254","https://openalex.org/W2078524519","https://openalex.org/W2089371040","https://openalex.org/W2101487986","https://openalex.org/W2102099319","https://openalex.org/W2103069600","https://openalex.org/W2105991991","https://openalex.org/W2113576511","https://openalex.org/W2116114482","https://openalex.org/W2120973488","https://openalex.org/W2138790588","https://openalex.org/W2144314866","https://openalex.org/W2156311276","https://openalex.org/W2157848968","https://openalex.org/W2158728639","https://openalex.org/W2159956122","https://openalex.org/W2169212716","https://openalex.org/W2171051269","https://openalex.org/W4241414925","https://openalex.org/W6639551022"],"related_works":["https://openalex.org/W2568858292","https://openalex.org/W2915014248","https://openalex.org/W1515964938","https://openalex.org/W2389381914","https://openalex.org/W3181296946","https://openalex.org/W2376528221","https://openalex.org/W2359428812","https://openalex.org/W2331917905","https://openalex.org/W3155039083","https://openalex.org/W1970914699"],"abstract_inverted_index":{"Tensor-based":[0],"morphometry":[1],"is":[2,76],"a":[3,25,43,64],"powerful":[4],"tool":[5],"for":[6],"automatically":[7],"computing":[8],"longitudinal":[9],"change":[10,59,75],"in":[11,17,20],"brain":[12],"structure.":[13],"Because":[14],"of":[15,37,56,128],"bias":[16],"images":[18],"and":[19,28,49,86,93,99,124],"the":[21,35,46,84,90,126],"algorithm":[22],"itself,":[23],"however,":[24],"penalty":[26,91],"term":[27,92],"inverse":[29,94],"consistency":[30,95],"are":[31],"needed":[32],"to":[33,53,78,82,118],"control":[34],"over-reporting":[36],"nonbiological":[38],"change.":[39],"These":[40],"may":[41],"force":[42],"tradeoff":[44],"between":[45],"intrinsic":[47],"sensitivity":[48,108],"specificity,":[50],"potentially":[51],"leading":[52],"an":[54],"under-reporting":[55],"authentic":[57],"biological":[58,74],"with":[60],"time.":[61],"We":[62],"propose":[63],"new":[65],"method":[66,105],"incorporating":[67],"prior":[68],"information":[69],"about":[70],"tissue":[71],"boundaries":[72],"(where":[73],"likely":[77],"exist)":[79],"that":[80,103],"aims":[81],"keep":[83],"robustness":[85],"specificity":[87],"contributed":[88],"by":[89],"while":[96],"maintaining":[97],"localization":[98],"sensitivity.":[100],"Results":[101],"indicate":[102],"this":[104],"has":[106],"improved":[107],"without":[109],"increased":[110],"noise.":[111],"Thus":[112],"it":[113],"will":[114],"have":[115],"enhanced":[116],"power":[117],"detect":[119],"differences":[120],"within":[121],"normal":[122],"aging":[123],"along":[125],"spectrum":[127],"cognitive":[129],"impairment.":[130]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}