{"id":"https://openalex.org/W2100073770","doi":"https://doi.org/10.1109/tmi.2011.2112669","title":"Hybrid Small Animal Imaging System Combining Magnetic Resonance Imaging With Fluorescence Tomography Using Single Photon Avalanche Diode Detectors","display_name":"Hybrid Small Animal Imaging System Combining Magnetic Resonance Imaging With Fluorescence Tomography Using Single Photon Avalanche Diode Detectors","publication_year":2011,"publication_date":"2011-02-11","ids":{"openalex":"https://openalex.org/W2100073770","doi":"https://doi.org/10.1109/tmi.2011.2112669","mag":"2100073770","pmid":"https://pubmed.ncbi.nlm.nih.gov/21317083"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2011.2112669","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2011.2112669","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://infoscience.epfl.ch/record/178076","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004065817","display_name":"Florian Stuker","orcid":null},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4210090941","display_name":"Institute for Biomedical Engineering","ror":"https://ror.org/00baskk38","country_code":"CH","type":"facility","lineage":["https://openalex.org/I202697423","https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4210090941"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Florian Stuker","raw_affiliation_strings":["Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland. stuker@biomed.ee.ethz.ch","Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland"],"affiliations":[{"raw_affiliation_string":"Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland. stuker@biomed.ee.ethz.ch","institution_ids":["https://openalex.org/I4210090941","https://openalex.org/I35440088"]},{"raw_affiliation_string":"Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210090941","https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089282830","display_name":"Christof Baltes","orcid":null},"institutions":[{"id":"https://openalex.org/I4210090941","display_name":"Institute for Biomedical Engineering","ror":"https://ror.org/00baskk38","country_code":"CH","type":"facility","lineage":["https://openalex.org/I202697423","https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4210090941"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Christof Baltes","raw_affiliation_strings":["Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland"],"affiliations":[{"raw_affiliation_string":"Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210090941","https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065771499","display_name":"Katerina Dikaiou","orcid":null},"institutions":[{"id":"https://openalex.org/I4210090941","display_name":"Institute for Biomedical Engineering","ror":"https://ror.org/00baskk38","country_code":"CH","type":"facility","lineage":["https://openalex.org/I202697423","https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4210090941"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Katerina Dikaiou","raw_affiliation_strings":["Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland"],"affiliations":[{"raw_affiliation_string":"Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210090941","https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048478753","display_name":"Divya Vats","orcid":null},"institutions":[{"id":"https://openalex.org/I4210090941","display_name":"Institute for Biomedical Engineering","ror":"https://ror.org/00baskk38","country_code":"CH","type":"facility","lineage":["https://openalex.org/I202697423","https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4210090941"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Divya Vats","raw_affiliation_strings":["Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland"],"affiliations":[{"raw_affiliation_string":"Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210090941","https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071399320","display_name":"Lucio Carrara","orcid":null},"institutions":[{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Lucio Carrara","raw_affiliation_strings":["Aqua Group, EPF Lausanne, Lausanne, Switzerland"],"affiliations":[{"raw_affiliation_string":"Aqua Group, EPF Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I5124864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026782847","display_name":"Edoardo Charbon","orcid":"https://orcid.org/0000-0002-0620-3365"},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4210090941","display_name":"Institute for Biomedical Engineering","ror":"https://ror.org/00baskk38","country_code":"CH","type":"facility","lineage":["https://openalex.org/I202697423","https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4210090941"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Edoardo Charbon","raw_affiliation_strings":["Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland"],"affiliations":[{"raw_affiliation_string":"Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210090941","https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001905057","display_name":"Jorge Ripoll","orcid":"https://orcid.org/0000-0001-8856-7738"},"institutions":[{"id":"https://openalex.org/I4210127348","display_name":"FORTH Institute of Electronic Structure and Laser","ror":"https://ror.org/02a3mhk13","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210127348","https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Jorge Ripoll","raw_affiliation_strings":["Institute of Electronic Structure and Laser, FORTH, Heraklion, Greece"],"affiliations":[{"raw_affiliation_string":"Institute of Electronic Structure and Laser, FORTH, Heraklion, Greece","institution_ids":["https://openalex.org/I4210127348"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048109297","display_name":"Markus Rudin","orcid":"https://orcid.org/0000-0003-4979-6567"},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4210090941","display_name":"Institute for Biomedical Engineering","ror":"https://ror.org/00baskk38","country_code":"CH","type":"facility","lineage":["https://openalex.org/I202697423","https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4210090941"]},{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Markus Rudin","raw_affiliation_strings":["Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland","Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland"],"affiliations":[{"raw_affiliation_string":"Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210090941","https://openalex.org/I35440088"]},{"raw_affiliation_string":"Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I202697423"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5004065817"],"corresponding_institution_ids":["https://openalex.org/I35440088","https://openalex.org/I4210090941"],"apc_list":null,"apc_paid":null,"fwci":6.5622,"has_fulltext":false,"cited_by_count":75,"citation_normalized_percentile":{"value":0.9681605,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"30","issue":"6","first_page":"1265","last_page":"1273"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.6410162448883057},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.6073950529098511},{"id":"https://openalex.org/keywords/diffuse-optical-imaging","display_name":"Diffuse optical imaging","score":0.5775325894355774},{"id":"https://openalex.org/keywords/tomographic-reconstruction","display_name":"Tomographic reconstruction","score":0.5706855654716492},{"id":"https://openalex.org/keywords/fluorescence-lifetime-imaging-microscopy","display_name":"Fluorescence-lifetime imaging microscopy","score":0.553825318813324},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.542971670627594},{"id":"https://openalex.org/keywords/fluorophore","display_name":"Fluorophore","score":0.5386462211608887},{"id":"https://openalex.org/keywords/molecular-imaging","display_name":"Molecular imaging","score":0.5286619663238525},{"id":"https://openalex.org/keywords/preclinical-imaging","display_name":"Preclinical imaging","score":0.506672203540802},{"id":"https://openalex.org/keywords/optical-tomography","display_name":"Optical tomography","score":0.47933825850486755},{"id":"https://openalex.org/keywords/tomography","display_name":"Tomography","score":0.4693796634674072},{"id":"https://openalex.org/keywords/detector","display_name":"Detector","score":0.44944077730178833},{"id":"https://openalex.org/keywords/fluorescence","display_name":"Fluorescence","score":0.39902400970458984},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3871227204799652},{"id":"https://openalex.org/keywords/nuclear-magnetic-resonance","display_name":"Nuclear magnetic resonance","score":0.36021360754966736},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.19294145703315735},{"id":"https://openalex.org/keywords/in-vivo","display_name":"In vivo","score":0.19265621900558472},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.07735684514045715},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.07698073983192444}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6410162448883057},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.6073950529098511},{"id":"https://openalex.org/C145417883","wikidata":"https://www.wikidata.org/wiki/Q5275421","display_name":"Diffuse optical imaging","level":3,"score":0.5775325894355774},{"id":"https://openalex.org/C97742081","wikidata":"https://www.wikidata.org/wiki/Q7820109","display_name":"Tomographic reconstruction","level":3,"score":0.5706855654716492},{"id":"https://openalex.org/C57477423","wikidata":"https://www.wikidata.org/wiki/Q1434196","display_name":"Fluorescence-lifetime imaging microscopy","level":3,"score":0.553825318813324},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.542971670627594},{"id":"https://openalex.org/C2778617687","wikidata":"https://www.wikidata.org/wiki/Q2448456","display_name":"Fluorophore","level":3,"score":0.5386462211608887},{"id":"https://openalex.org/C136339569","wikidata":"https://www.wikidata.org/wiki/Q1142297","display_name":"Molecular imaging","level":3,"score":0.5286619663238525},{"id":"https://openalex.org/C29331040","wikidata":"https://www.wikidata.org/wiki/Q7239554","display_name":"Preclinical imaging","level":3,"score":0.506672203540802},{"id":"https://openalex.org/C2777413408","wikidata":"https://www.wikidata.org/wiki/Q1968843","display_name":"Optical tomography","level":3,"score":0.47933825850486755},{"id":"https://openalex.org/C163716698","wikidata":"https://www.wikidata.org/wiki/Q841267","display_name":"Tomography","level":2,"score":0.4693796634674072},{"id":"https://openalex.org/C94915269","wikidata":"https://www.wikidata.org/wiki/Q1834857","display_name":"Detector","level":2,"score":0.44944077730178833},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.39902400970458984},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3871227204799652},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.36021360754966736},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.19294145703315735},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.19265621900558472},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07735684514045715},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.07698073983192444},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D008856","descriptor_name":"Microscopy, Fluorescence","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D008856","descriptor_name":"Microscopy, Fluorescence","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D008856","descriptor_name":"Microscopy, Fluorescence","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D008856","descriptor_name":"Microscopy, Fluorescence","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D008856","descriptor_name":"Microscopy, Fluorescence","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D008856","descriptor_name":"Microscopy, Fluorescence","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D008904","descriptor_name":"Miniaturization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008904","descriptor_name":"Miniaturization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008904","descriptor_name":"Miniaturization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010783","descriptor_name":"Photometry","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D010783","descriptor_name":"Photometry","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D010783","descriptor_name":"Photometry","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D010783","descriptor_name":"Photometry","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D010783","descriptor_name":"Photometry","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D010783","descriptor_name":"Photometry","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D012666","descriptor_name":"Semiconductors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012666","descriptor_name":"Semiconductors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012666","descriptor_name":"Semiconductors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013382","descriptor_name":"Subtraction Technique","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D013382","descriptor_name":"Subtraction Technique","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D013382","descriptor_name":"Subtraction Technique","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D013382","descriptor_name":"Subtraction Technique","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D013382","descriptor_name":"Subtraction Technique","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D013382","descriptor_name":"Subtraction Technique","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D014159","descriptor_name":"Transducers","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D014159","descriptor_name":"Transducers","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D014159","descriptor_name":"Transducers","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017785","descriptor_name":"Photons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017785","descriptor_name":"Photons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017785","descriptor_name":"Photons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1109/tmi.2011.2112669","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2011.2112669","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:21317083","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21317083","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.418.2321","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.418.2321","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://ens.ewi.tudelft.nl/pubs/charbon11tmi.pdf","raw_type":"text"},{"id":"pmh:oai:infoscience.epfl.ch:178076","is_oa":true,"landing_page_url":"http://infoscience.epfl.ch/record/178076","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:www.zora.uzh.ch:53720","is_oa":false,"landing_page_url":"https://www.zora.uzh.ch/53720","pdf_url":null,"source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Stuker, F; Baltes, C; Dikaiou, K; Vats, D; Carrara, L; Charbon, E; Ripoll, J; Rudin, M  (2011). Hybrid small animal imaging system combining magnetic resonance imaging with fluorescence tomography using single photon avalanche diode detectors.  IEEE Transactions on Medical Imaging, 30(6):1265-1273.","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:infoscience.epfl.ch:178076","is_oa":true,"landing_page_url":"http://infoscience.epfl.ch/record/178076","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1165229630","display_name":"Critique des donn\u00e9es n\u00e9cessaires pour la simulation num\u00e9rique d'une nappe souterraine. Application \u00e0 la nappe de l'Arve","funder_award_id":"10030","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G4459847873","display_name":null,"funder_award_id":"310030-126029","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G773317043","display_name":"Noninvasive quantitative imaging of amyloid plaque load in the brain of genetically engineered mouse models of cerebral amyloidosis","funder_award_id":"112835","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G8051717526","display_name":null,"funder_award_id":"Grant","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8690818240","display_name":null,"funder_award_id":"310030","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G8954454020","display_name":"Droit \u00e9conomique et commercial international et compar\u00e9.","funder_award_id":"26029","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G8978649484","display_name":"Noninvasive quantitative imaging of amyloid plaque load in the brain of genetically engineered mouse models of cerebral amyloidosis","funder_award_id":"126029","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G971298448","display_name":null,"funder_award_id":"31003","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1898110144","https://openalex.org/W1910923695","https://openalex.org/W1964293644","https://openalex.org/W1965308573","https://openalex.org/W2019230763","https://openalex.org/W2025396449","https://openalex.org/W2037521346","https://openalex.org/W2037692116","https://openalex.org/W2039026859","https://openalex.org/W2040139677","https://openalex.org/W2047615998","https://openalex.org/W2050014887","https://openalex.org/W2050907119","https://openalex.org/W2056780279","https://openalex.org/W2063422023","https://openalex.org/W2069638680","https://openalex.org/W2084202469","https://openalex.org/W2084985760","https://openalex.org/W2086018477","https://openalex.org/W2090985686","https://openalex.org/W2106271386","https://openalex.org/W2126639779","https://openalex.org/W2130193058","https://openalex.org/W2134096426","https://openalex.org/W2148588305","https://openalex.org/W2152386347","https://openalex.org/W2159091624","https://openalex.org/W2160463229","https://openalex.org/W2163801680","https://openalex.org/W6639677835","https://openalex.org/W6639950471","https://openalex.org/W6684073665"],"related_works":["https://openalex.org/W2037916999","https://openalex.org/W2073776015","https://openalex.org/W2318737792","https://openalex.org/W4385335355","https://openalex.org/W3010250986","https://openalex.org/W2111495568","https://openalex.org/W2053862543","https://openalex.org/W2164004284","https://openalex.org/W2010236750","https://openalex.org/W2092074255"],"abstract_inverted_index":{"The":[0],"high":[1,61],"sensitivity":[2],"of":[3,9,24,58,99,135,141,145,154],"fluorescence":[4,50,77,108],"imaging":[5,42,51,73],"enables":[6,55],"the":[7,56,97],"detection":[8,112],"molecular":[10,59,78],"processes":[11],"in":[12,19,149,160],"living":[13],"organisms.":[14],"However,":[15],"diffuse":[16],"light":[17],"propagation":[18],"tissue":[20],"prevents":[21],"accurate":[22,46,139],"recovery":[23],"tomographic":[25],"information":[26],"on":[27,114],"fluorophore":[28],"distribution":[29],"for":[30,49,70,106],"structures":[31],"embedded":[32],"deeper":[33],"than":[34],"0.5":[35],"mm.":[36],"Combining":[37],"optical":[38,100],"with":[39,60],"magnetic":[40],"resonance":[41],"(MRI)":[43],"provides":[44],"an":[45,67,83],"anatomical":[47],"reference":[48],"data":[52,137],"and":[53,138,157],"thereby":[54],"correlation":[57],"quality":[62],"structural/functional":[63],"information.":[64],"We":[65],"describe":[66],"integrated":[68],"system":[69,81],"small":[71],"animal":[72],"incorporating":[74],"a":[75,88,115],"noncontact":[76],"tomography":[79],"(FMT)":[80],"into":[82],"MRI":[84],"detector.":[85],"By":[86],"adopting":[87],"free":[89],"laser":[90],"beam":[91],"design":[92],"geometrical":[93],"constraints":[94],"imposed":[95],"by":[96,151],"use":[98],"fibers":[101],"could":[102],"be":[103],"avoided":[104],"allowing":[105],"flexible":[107],"excitation":[109],"schemes.":[110],"Photon":[111],"based":[113],"single-photon":[116],"avalanche":[117],"diode":[118],"array":[119],"enabled":[120],"simultaneous":[121,152],"FMT/MRI":[122,146],"measurements":[123],"without":[124],"interference":[125],"between":[126],"modalities.":[127],"In":[128],"vitro":[129],"characterization":[130],"revealed":[131],"good":[132],"spatial":[133],"accuracy":[134],"FMT":[136],"quantification":[140],"dye":[142],"concentrations.":[143],"Feasibility":[144],"was":[147],"demonstrated":[148],"vivo":[150],"assessment":[153],"protease":[155],"activity":[156],"tumor":[158],"morphology":[159],"murine":[161],"colon":[162],"cancer":[163],"xenografts.":[164]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":9}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}