{"id":"https://openalex.org/W2107799700","doi":"https://doi.org/10.1109/tmi.2009.2031492","title":"Discretization Error Analysis and Adaptive Meshing Algorithms for Fluorescence Diffuse Optical Tomography: Part I","display_name":"Discretization Error Analysis and Adaptive Meshing Algorithms for Fluorescence Diffuse Optical Tomography: Part I","publication_year":2010,"publication_date":"2010-02-01","ids":{"openalex":"https://openalex.org/W2107799700","doi":"https://doi.org/10.1109/tmi.2009.2031492","mag":"2107799700","pmid":"https://pubmed.ncbi.nlm.nih.gov/20129842"},"language":"en","primary_location":{"id":"doi:10.1109/tmi.2009.2031492","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2009.2031492","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052382855","display_name":"Murat Guven","orcid":null},"institutions":[{"id":"https://openalex.org/I1343180700","display_name":"Intel (United States)","ror":"https://ror.org/01ek73717","country_code":"US","type":"company","lineage":["https://openalex.org/I1343180700"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Guven","raw_affiliation_strings":["Intel Corporation, Santa Clara, CA 95054 USA. guven@rpi.edu","Santa Clara, Intel Corporation, Santa Clara, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Intel Corporation, Santa Clara, CA 95054 USA. guven@rpi.edu","institution_ids":["https://openalex.org/I1343180700"]},{"raw_affiliation_string":"Santa Clara, Intel Corporation, Santa Clara, CA, USA","institution_ids":["https://openalex.org/I1343180700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031225594","display_name":"Laurel K. Reilly-Raska","orcid":null},"institutions":[{"id":"https://openalex.org/I4210122954","display_name":"MIT Lincoln Laboratory","ror":"https://ror.org/022z6jk58","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210122954","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Reilly-Raska","raw_affiliation_strings":["Lincoln Laboratory, Massachusetts Institute of Technology, Lexington, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lincoln Laboratory, Massachusetts Institute of Technology, Lexington, MA, USA","institution_ids":["https://openalex.org/I4210122954","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044087584","display_name":"Lu Zhou","orcid":"https://orcid.org/0000-0002-7215-6245"},"institutions":[{"id":"https://openalex.org/I165799507","display_name":"Rensselaer Polytechnic Institute","ror":"https://ror.org/01rtyzb94","country_code":"US","type":"education","lineage":["https://openalex.org/I165799507"]},{"id":"https://openalex.org/I4210122954","display_name":"MIT Lincoln Laboratory","ror":"https://ror.org/022z6jk58","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210122954","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lu Zhou","raw_affiliation_strings":["Departments of Electrical Computer and Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA","Lincoln Laboratory, Massachusetts Institute of Technology, Lexington, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Electrical Computer and Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA","institution_ids":["https://openalex.org/I165799507"]},{"raw_affiliation_string":"Lincoln Laboratory, Massachusetts Institute of Technology, Lexington, MA, USA","institution_ids":["https://openalex.org/I4210122954","https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056090082","display_name":"Birsen Yaz\u0131c\u0131","orcid":"https://orcid.org/0000-0002-0912-0848"},"institutions":[{"id":"https://openalex.org/I165799507","display_name":"Rensselaer Polytechnic Institute","ror":"https://ror.org/01rtyzb94","country_code":"US","type":"education","lineage":["https://openalex.org/I165799507"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B. Yazici","raw_affiliation_strings":["Departments of Electrical Computer and Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Electrical Computer and Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA","institution_ids":["https://openalex.org/I165799507"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2605,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.80758239,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"29","issue":"2","first_page":"217","last_page":"229"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11205","display_name":"Numerical methods in inverse problems","score":0.9898999929428101,"subfield":{"id":"https://openalex.org/subfields/2610","display_name":"Mathematical Physics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/discretization","display_name":"Discretization","score":0.8786414861679077},{"id":"https://openalex.org/keywords/inverse-problem","display_name":"Inverse problem","score":0.7228760123252869},{"id":"https://openalex.org/keywords/diffuse-optical-imaging","display_name":"Diffuse optical imaging","score":0.5769137740135193},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4939904808998108},{"id":"https://openalex.org/keywords/finite-element-method","display_name":"Finite element method","score":0.48233696818351746},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.4561033844947815},{"id":"https://openalex.org/keywords/applied-mathematics","display_name":"Applied mathematics","score":0.4480481743812561},{"id":"https://openalex.org/keywords/inverse","display_name":"Inverse","score":0.4425019323825836},{"id":"https://openalex.org/keywords/regularization","display_name":"Regularization (linguistics)","score":0.43033742904663086},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4208429455757141},{"id":"https://openalex.org/keywords/tikhonov-regularization","display_name":"Tikhonov regularization","score":0.4172112047672272},{"id":"https://openalex.org/keywords/discretization-of-continuous-features","display_name":"Discretization of continuous features","score":0.4136744439601898},{"id":"https://openalex.org/keywords/a-priori-and-a-posteriori","display_name":"A priori and a posteriori","score":0.4121832847595215},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.34959930181503296},{"id":"https://openalex.org/keywords/iterative-reconstruction","display_name":"Iterative reconstruction","score":0.30667608976364136},{"id":"https://openalex.org/keywords/mathematical-analysis","display_name":"Mathematical analysis","score":0.2623659372329712},{"id":"https://openalex.org/keywords/discretization-error","display_name":"Discretization error","score":0.17886129021644592},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.1361624300479889},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.12427499890327454},{"id":"https://openalex.org/keywords/geometry","display_name":"Geometry","score":0.11721235513687134}],"concepts":[{"id":"https://openalex.org/C73000952","wikidata":"https://www.wikidata.org/wiki/Q17007827","display_name":"Discretization","level":2,"score":0.8786414861679077},{"id":"https://openalex.org/C135252773","wikidata":"https://www.wikidata.org/wiki/Q1567213","display_name":"Inverse problem","level":2,"score":0.7228760123252869},{"id":"https://openalex.org/C145417883","wikidata":"https://www.wikidata.org/wiki/Q5275421","display_name":"Diffuse optical imaging","level":3,"score":0.5769137740135193},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4939904808998108},{"id":"https://openalex.org/C135628077","wikidata":"https://www.wikidata.org/wiki/Q220184","display_name":"Finite element method","level":2,"score":0.48233696818351746},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.4561033844947815},{"id":"https://openalex.org/C28826006","wikidata":"https://www.wikidata.org/wiki/Q33521","display_name":"Applied mathematics","level":1,"score":0.4480481743812561},{"id":"https://openalex.org/C207467116","wikidata":"https://www.wikidata.org/wiki/Q4385666","display_name":"Inverse","level":2,"score":0.4425019323825836},{"id":"https://openalex.org/C2776135515","wikidata":"https://www.wikidata.org/wiki/Q17143721","display_name":"Regularization (linguistics)","level":2,"score":0.43033742904663086},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4208429455757141},{"id":"https://openalex.org/C152442038","wikidata":"https://www.wikidata.org/wiki/Q2778212","display_name":"Tikhonov regularization","level":3,"score":0.4172112047672272},{"id":"https://openalex.org/C105427703","wikidata":"https://www.wikidata.org/wiki/Q665193","display_name":"Discretization of continuous features","level":4,"score":0.4136744439601898},{"id":"https://openalex.org/C75553542","wikidata":"https://www.wikidata.org/wiki/Q178161","display_name":"A priori and a posteriori","level":2,"score":0.4121832847595215},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.34959930181503296},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.30667608976364136},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.2623659372329712},{"id":"https://openalex.org/C126148662","wikidata":"https://www.wikidata.org/wiki/Q3890355","display_name":"Discretization error","level":3,"score":0.17886129021644592},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1361624300479889},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.12427499890327454},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.11721235513687134},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005453","descriptor_name":"Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005453","descriptor_name":"Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005453","descriptor_name":"Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020342","descriptor_name":"Finite Element Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020342","descriptor_name":"Finite Element Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020342","descriptor_name":"Finite Element Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tmi.2009.2031492","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmi.2009.2031492","pdf_url":null,"source":{"id":"https://openalex.org/S58069681","display_name":"IEEE Transactions on Medical Imaging","issn_l":"0278-0062","issn":["0278-0062","1558-254X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Medical Imaging","raw_type":"journal-article"},{"id":"pmid:20129842","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20129842","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on medical imaging","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":58,"referenced_works":["https://openalex.org/W40037269","https://openalex.org/W591221906","https://openalex.org/W604177120","https://openalex.org/W1492326914","https://openalex.org/W1493981498","https://openalex.org/W1531455566","https://openalex.org/W1533569303","https://openalex.org/W1567244019","https://openalex.org/W1968735445","https://openalex.org/W1974424152","https://openalex.org/W1976357678","https://openalex.org/W1976435787","https://openalex.org/W1989594010","https://openalex.org/W1990381576","https://openalex.org/W1992522720","https://openalex.org/W1994336408","https://openalex.org/W2009814556","https://openalex.org/W2014303698","https://openalex.org/W2023474980","https://openalex.org/W2025642183","https://openalex.org/W2033106066","https://openalex.org/W2047615998","https://openalex.org/W2052635053","https://openalex.org/W2056027508","https://openalex.org/W2060819023","https://openalex.org/W2069009977","https://openalex.org/W2069156483","https://openalex.org/W2071036364","https://openalex.org/W2071182807","https://openalex.org/W2071544995","https://openalex.org/W2075127061","https://openalex.org/W2082425338","https://openalex.org/W2085231630","https://openalex.org/W2085510720","https://openalex.org/W2088955745","https://openalex.org/W2095715860","https://openalex.org/W2097879622","https://openalex.org/W2102295719","https://openalex.org/W2106147817","https://openalex.org/W2107799700","https://openalex.org/W2110483649","https://openalex.org/W2115657970","https://openalex.org/W2116641053","https://openalex.org/W2117519878","https://openalex.org/W2120062331","https://openalex.org/W2123913404","https://openalex.org/W2130002602","https://openalex.org/W2130611075","https://openalex.org/W2141471272","https://openalex.org/W2144534840","https://openalex.org/W2163108870","https://openalex.org/W2163887005","https://openalex.org/W2483892835","https://openalex.org/W2810685934","https://openalex.org/W3039083618","https://openalex.org/W4232421488","https://openalex.org/W4292361795","https://openalex.org/W4302436815"],"related_works":["https://openalex.org/W2749105521","https://openalex.org/W2360343897","https://openalex.org/W140737605","https://openalex.org/W2564453433","https://openalex.org/W2058033086","https://openalex.org/W3188213007","https://openalex.org/W2374214022","https://openalex.org/W1947575127","https://openalex.org/W2029137001","https://openalex.org/W376746440"],"abstract_inverted_index":{"For":[0,81],"imaging":[1],"problems":[2,145],"in":[3,97,133],"which":[4,90,150],"numerical":[5,75,207],"solutions":[6],"need":[7],"to":[8,121,137,158,185,220],"be":[9,22],"computed":[10],"for":[11,73],"both":[12],"the":[13,16,28,37,42,51,61,74,78,82,98,110,123,127,131,138,141,153,163,167,172,189,192,198,210,214],"inverse":[14,83,111,124,144,170,193],"and":[15,63,66,102,117,143,146,169,176,180,188,200],"underlying":[17],"forward":[18,52,79,142,168],"problems,":[19,171],"discretization":[20,40,71,139,224],"can":[21],"a":[23,55,68,94,114],"major":[24],"factor":[25],"that":[26,155],"determines":[27],"accuracy":[29,43],"of":[30,39,44,57,77,93,100,140,166,174,191,202,213],"imaging.":[31],"In":[32,209],"this":[33],"work,":[34],"we":[35,85,108,129,196,216],"analyze":[36,130],"effect":[38],"on":[41],"fluorescence":[45],"diffuse":[46],"optical":[47],"tomography.":[48],"We":[49],"model":[50],"problem":[53,112,116],"by":[54,206],"pair":[56],"diffusion":[58],"equations":[59],"at":[60],"excitation":[62],"emission":[64],"wavelengths":[65],"consider":[67],"finite":[69],"element":[70],"method":[72],"solution":[76],"problem.":[80,125,194],"problem,":[84],"use":[86,118],"an":[87],"optimization":[88],"framework":[89],"allows":[91],"incorporation":[92],"priori":[95],"information":[96],"form":[99],"zeroth-":[101],"first-order":[103],"Tikhonov":[104],"regularization":[105],"terms.":[106],"Next,":[107],"convert":[109],"into":[113],"variational":[115],"Galerkin":[119],"projection":[120],"discretize":[122],"Following":[126],"discretization,":[128],"error":[132,160,204],"reconstructed":[134],"images":[135],"due":[136],"present":[147],"two":[148],"theorems":[149],"point":[151],"out":[152],"factors":[154],"may":[156],"lead":[157],"high":[159],"such":[161],"as":[162],"mutual":[164],"dependence":[165],"number":[173],"sources":[175],"detectors,":[177],"their":[178,181],"configuration":[179],"positions":[182],"with":[183],"respect":[184],"fluorophore":[186],"concentration,":[187],"formulation":[190],"Finally,":[195],"demonstrate":[197],"results":[199,219],"implications":[201],"our":[203,218],"analysis":[205],"experiments.":[208],"second":[211],"part":[212],"paper,":[215],"apply":[217],"design":[221],"novel":[222],"adaptive":[223],"algorithms.":[225]},"counts_by_year":[{"year":2019,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}