{"id":"https://openalex.org/W4402569411","doi":"https://doi.org/10.1109/tmbmc.2024.3462727","title":"Molecular Quantum (MolQ) Communication Channel in the Gut-Brain Axis Synapse","display_name":"Molecular Quantum (MolQ) Communication Channel in the Gut-Brain Axis Synapse","publication_year":2024,"publication_date":"2024-09-17","ids":{"openalex":"https://openalex.org/W4402569411","doi":"https://doi.org/10.1109/tmbmc.2024.3462727"},"language":"en","primary_location":{"id":"doi:10.1109/tmbmc.2024.3462727","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmbmc.2024.3462727","pdf_url":null,"source":{"id":"https://openalex.org/S2490853239","display_name":"IEEE Transactions on Molecular Biological and Multi-Scale Communications","issn_l":"2332-7804","issn":["2332-7804","2372-2061"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057707623","display_name":"Bitop Maitra","orcid":"https://orcid.org/0000-0003-3948-229X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bitop Maitra","raw_affiliation_strings":["Department of Electrical and Electronics Engineering, Center for neXt-generation Communications (CXC), Ko&#x00E7; University, Istanbul, Turkey"],"raw_orcid":"https://orcid.org/0000-0003-3948-229X","affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronics Engineering, Center for neXt-generation Communications (CXC), Ko&#x00E7; University, Istanbul, Turkey","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042130660","display_name":"\u00d6zg\u00fcr B. Akan","orcid":"https://orcid.org/0000-0003-2523-3858"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ozgur B. Akan","raw_affiliation_strings":["Department of Electrical and Electronics Engineering, Center for neXt-generation Communications (CXC), Ko&#x00E7; University, Istanbul, Turkey"],"raw_orcid":"https://orcid.org/0000-0003-2523-3858","affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronics Engineering, Center for neXt-generation Communications (CXC), Ko&#x00E7; University, Istanbul, Turkey","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4829,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.60363545,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"10","issue":"4","first_page":"604","last_page":"612"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13052","display_name":"Molecular Communication and Nanonetworks","score":0.9710999727249146,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13052","display_name":"Molecular Communication and Nanonetworks","score":0.9710999727249146,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9621999859809875,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/synapse","display_name":"Synapse","score":0.5843323469161987},{"id":"https://openalex.org/keywords/channel","display_name":"Channel (broadcasting)","score":0.49034571647644043},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.4839182496070862},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.39340412616729736},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.34244850277900696},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.26953059434890747},{"id":"https://openalex.org/keywords/computer-network","display_name":"Computer network","score":0.18463566899299622}],"concepts":[{"id":"https://openalex.org/C127445978","wikidata":"https://www.wikidata.org/wiki/Q187181","display_name":"Synapse","level":2,"score":0.5843323469161987},{"id":"https://openalex.org/C127162648","wikidata":"https://www.wikidata.org/wiki/Q16858953","display_name":"Channel (broadcasting)","level":2,"score":0.49034571647644043},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4839182496070862},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.39340412616729736},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.34244850277900696},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.26953059434890747},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.18463566899299622}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/tmbmc.2024.3462727","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tmbmc.2024.3462727","pdf_url":null,"source":{"id":"https://openalex.org/S2490853239","display_name":"IEEE Transactions on Molecular Biological and Multi-Scale Communications","issn_l":"2332-7804","issn":["2332-7804","2372-2061"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321048","display_name":"AXA Research Fund","ror":"https://ror.org/02zxqxw53"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W1968128476","https://openalex.org/W1974849576","https://openalex.org/W1976818745","https://openalex.org/W1984920148","https://openalex.org/W1985940938","https://openalex.org/W1990323937","https://openalex.org/W1996185141","https://openalex.org/W2000129051","https://openalex.org/W2006413126","https://openalex.org/W2008002200","https://openalex.org/W2009551406","https://openalex.org/W2043590898","https://openalex.org/W2049647155","https://openalex.org/W2050327333","https://openalex.org/W2059093744","https://openalex.org/W2073882807","https://openalex.org/W2075562222","https://openalex.org/W2085139899","https://openalex.org/W2116194016","https://openalex.org/W2119259421","https://openalex.org/W2133301037","https://openalex.org/W2148126095","https://openalex.org/W2150075151","https://openalex.org/W2159785127","https://openalex.org/W2163496989","https://openalex.org/W2334173195","https://openalex.org/W2619109450","https://openalex.org/W2755483873","https://openalex.org/W2790416725","https://openalex.org/W2794333910","https://openalex.org/W2898390164","https://openalex.org/W2908925932","https://openalex.org/W2954096078","https://openalex.org/W2963970956","https://openalex.org/W2987309209","https://openalex.org/W3007159566","https://openalex.org/W3037776276","https://openalex.org/W3067594884","https://openalex.org/W3153509308","https://openalex.org/W4210955860","https://openalex.org/W4212861831","https://openalex.org/W4292414234","https://openalex.org/W4297238654","https://openalex.org/W4309664380","https://openalex.org/W4322775721","https://openalex.org/W4379795547","https://openalex.org/W4388041827","https://openalex.org/W4392645981","https://openalex.org/W6636890641","https://openalex.org/W6851714193","https://openalex.org/W6861150088","https://openalex.org/W7009171728"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2935759653","https://openalex.org/W3105167352","https://openalex.org/W54078636","https://openalex.org/W2954470139","https://openalex.org/W1501425562","https://openalex.org/W2902782467","https://openalex.org/W3084825885","https://openalex.org/W2298861036","https://openalex.org/W2271181815"],"abstract_inverted_index":{"The":[0],"gut-brain":[1,19,80],"axis":[2,20],"is":[3,15,30,41,155],"the":[4,8,11,18,44,52,68,71,79,86,93,99,103,113,116,121,125,128,144,150,158,166,169,173],"communication":[5,40,109,122,136],"link":[6],"between":[7],"gut":[9,126],"and":[10,153,162,168,178],"brain.":[12,129],"Although":[13],"it":[14,105],"known":[16],"that":[17,62],"plays":[21],"a":[22,107,132],"pivotal":[23],"role":[24],"in":[25],"homeostasis,":[26],"its":[27],"overall":[28],"mechanism":[29],"still":[31],"not":[32],"known.":[33],"However,":[34],"for":[35],"neural":[36],"synapses,":[37],"classical":[38],"molecular":[39,90],"described":[42],"by":[43,164],"formation":[45],"of":[46,54,70,102,115,135,172],"ligand-receptor":[47],"complexes,":[48],"which":[49,111],"leads":[50],"to":[51,64,127],"opening":[53,69,114],"ion":[55,72,117,181],"channels.":[56],"Moreover,":[57],"there":[58],"are":[59],"some":[60],"conditions":[61],"need":[63],"be":[65],"fulfilled":[66],"before":[67],"channel.":[73],"In":[74],"this":[75],"study,":[76],"we":[77,147],"consider":[78],"axis,":[81],"where":[82],"neurotransmitters":[83],"diffuse":[84],"through":[85],"synaptic":[87],"cleft,":[88],"considering":[89,157],"communication.":[91,141],"On":[92],"vagus":[94],"nerve":[95],"(VN)":[96],"membrane,":[97],"i.e.,":[98,175,180],"post-synaptic":[100],"membrane":[101],"synapse,":[104],"undergoes":[106],"quantum":[108],"(QC),":[110],"initiates":[112],"channel,":[118],"thus":[119],"initiating":[120],"signal":[123],"from":[124],"It":[130],"evolves":[131],"new":[133],"paradigm":[134],"approach,":[137],"Molecular":[138],"Quantum":[139],"(MolQ)":[140],"Based":[142],"on":[143],"QC":[145,154],"model,":[146],"theoretically":[148],"analyze":[149],"output":[151],"states,":[152],"simulated":[156],"incoming":[159],"neurotransmitter\u2019s":[160,176],"concentration":[161],"validated":[163],"analyzing":[165],"entropy":[167],"mutual":[170],"information":[171],"input,":[174],"concentration,":[177],"output,":[179],"channel":[182],"opening.":[183]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2}],"updated_date":"2026-06-18T10:00:31.954636","created_date":"2025-10-10T00:00:00"}
