{"id":"https://openalex.org/W4384159555","doi":"https://doi.org/10.1109/tmbmc.2023.3295338","title":"Affinity-Division Multiplexing for Molecular Communications With Promiscuous Ligand Receptors","display_name":"Affinity-Division Multiplexing for Molecular Communications With Promiscuous Ligand Receptors","publication_year":2023,"publication_date":"2023-07-13","ids":{"openalex":"https://openalex.org/W4384159555","doi":"https://doi.org/10.1109/tmbmc.2023.3295338"},"language":"en","primary_location":{"id":"doi:10.1109/tmbmc.2023.3295338","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/tmbmc.2023.3295338","pdf_url":null,"source":{"id":"https://openalex.org/S2490853239","display_name":"IEEE Transactions on Molecular Biological and Multi-Scale Communications","issn_l":"2332-7804","issn":["2332-7804","2372-2061"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Molecular, Biological and Multi-Scale Communications","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015182402","display_name":"Ahmet R. Emirdagi","orcid":null},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ahmet R. Emirdagi","raw_affiliation_strings":["Department of Electrical and Electronics Engineering, Nano/Bio/Physical Information and Communications Laboratory, Koç University, Istanbul, Turkey"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronics Engineering, Nano/Bio/Physical Information and Communications Laboratory, Koç University, Istanbul, Turkey","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040070616","display_name":"M. Serkan Kopuzlu","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Serkan Kopuzlu","raw_affiliation_strings":["Department of Electrical and Electronics Engineering, Nano/Bio/Physical Information and Communications Laboratory, Koç University, Istanbul, Turkey"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronics Engineering, Nano/Bio/Physical Information and Communications Laboratory, Koç University, Istanbul, Turkey","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070728886","display_name":"M. Okan Araz","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Okan Araz","raw_affiliation_strings":["Department of Electrical and Electronics Engineering, Nano/Bio/Physical Information and Communications Laboratory, Koç University, Istanbul, Turkey"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronics Engineering, Nano/Bio/Physical Information and Communications Laboratory, Koç University, Istanbul, Turkey","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048937970","display_name":"Murat Ku\u015fcu","orcid":"https://orcid.org/0000-0002-8463-6027"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Murat Kuscu","raw_affiliation_strings":["Department of Electrical and Electronics Engineering, Nano/Bio/Physical Information and Communications Laboratory, Koç University, Istanbul, Turkey"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronics Engineering, Nano/Bio/Physical Information and Communications Laboratory, Koç University, Istanbul, Turkey","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5015182402"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1125,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.39040884,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"9","issue":"3","first_page":"318","last_page":"322"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13052","display_name":"Molecular Communication and Nanonetworks","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13052","display_name":"Molecular Communication and Nanonetworks","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9918000102043152,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11932","display_name":"Wireless Body Area Networks","score":0.9905999898910522,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiplexing","display_name":"Multiplexing","score":0.8384804725646973},{"id":"https://openalex.org/keywords/statistical-time-division-multiplexing","display_name":"Statistical time division multiplexing","score":0.47773095965385437},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.4548126459121704},{"id":"https://openalex.org/keywords/leverage","display_name":"Leverage (statistics)","score":0.44065988063812256},{"id":"https://openalex.org/keywords/channel","display_name":"Channel (broadcasting)","score":0.42798754572868347},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.41080594062805176},{"id":"https://openalex.org/keywords/affinities","display_name":"Affinities","score":0.41018950939178467},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.3552681803703308},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.35177284479141235},{"id":"https://openalex.org/keywords/topology","display_name":"Topology (electrical circuits)","score":0.3482108414173126},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.32345062494277954},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.30711060762405396},{"id":"https://openalex.org/keywords/telecommunications","display_name":"Telecommunications","score":0.2751072645187378},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2711201310157776},{"id":"https://openalex.org/keywords/stereochemistry","display_name":"Stereochemistry","score":0.175550639629364},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.13241171836853027},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.09995415806770325},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.06709077954292297}],"concepts":[{"id":"https://openalex.org/C19275194","wikidata":"https://www.wikidata.org/wiki/Q222903","display_name":"Multiplexing","level":2,"score":0.8384804725646973},{"id":"https://openalex.org/C173512123","wikidata":"https://www.wikidata.org/wiki/Q5978010","display_name":"Statistical time division multiplexing","level":3,"score":0.47773095965385437},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4548126459121704},{"id":"https://openalex.org/C153083717","wikidata":"https://www.wikidata.org/wiki/Q6535263","display_name":"Leverage (statistics)","level":2,"score":0.44065988063812256},{"id":"https://openalex.org/C127162648","wikidata":"https://www.wikidata.org/wiki/Q16858953","display_name":"Channel (broadcasting)","level":2,"score":0.42798754572868347},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.41080594062805176},{"id":"https://openalex.org/C2780283098","wikidata":"https://www.wikidata.org/wiki/Q4688960","display_name":"Affinities","level":2,"score":0.41018950939178467},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3552681803703308},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.35177284479141235},{"id":"https://openalex.org/C184720557","wikidata":"https://www.wikidata.org/wiki/Q7825049","display_name":"Topology (electrical circuits)","level":2,"score":0.3482108414173126},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.32345062494277954},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.30711060762405396},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.2751072645187378},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2711201310157776},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.175550639629364},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13241171836853027},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.09995415806770325},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.06709077954292297}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/tmbmc.2023.3295338","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/tmbmc.2023.3295338","pdf_url":null,"source":{"id":"https://openalex.org/S2490853239","display_name":"IEEE Transactions on Molecular Biological and Multi-Scale Communications","issn_l":"2332-7804","issn":["2332-7804","2372-2061"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Molecular, Biological and Multi-Scale Communications","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1403622336","display_name":null,"funder_award_id":"120E301","funder_id":"https://openalex.org/F4320322626","funder_display_name":"T\u00fcrkiye Bilimsel ve Teknolojik Ara\u015ft\u0131rma Kurumu"}],"funders":[{"id":"https://openalex.org/F4320322626","display_name":"T\u00fcrkiye Bilimsel ve Teknolojik Ara\u015ft\u0131rma Kurumu","ror":"https://ror.org/04w9kkr77"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1892246357","https://openalex.org/W1924752536","https://openalex.org/W2071423255","https://openalex.org/W2148043530","https://openalex.org/W2169061810","https://openalex.org/W2556381928","https://openalex.org/W2605641522","https://openalex.org/W2759224817","https://openalex.org/W2967821152","https://openalex.org/W3018860287","https://openalex.org/W3122734871","https://openalex.org/W3135293353","https://openalex.org/W3184210572","https://openalex.org/W3201835288","https://openalex.org/W4200037314","https://openalex.org/W4242046293","https://openalex.org/W4300773841"],"related_works":["https://openalex.org/W3030636240","https://openalex.org/W431360389","https://openalex.org/W2063698109","https://openalex.org/W2166601301","https://openalex.org/W1538654733","https://openalex.org/W1580283584","https://openalex.org/W2361869782","https://openalex.org/W2045290981","https://openalex.org/W2044046257","https://openalex.org/W2388548392"],"abstract_inverted_index":{"A":[0],"key":[1],"challenge":[2],"in":[3,26,114],"Molecular":[4],"Communications":[5],"(MC)":[6],"is":[7,28,63],"low":[8],"data":[9],"transmission":[10],"rates,":[11],"which":[12,62],"can":[13],"be":[14],"addressed":[15],"by":[16],"channel":[17,24],"multiplexing":[18,25,58],"techniques.":[19],"One":[20],"way":[21],"to":[22,29,39],"achieve":[23],"MC":[27,105,151],"leverage":[30],"the":[31,66,83,96,120,124,130,140,147],"diversity":[32,67],"of":[33,68,79,87,110,116,122,126,132,142,149],"different":[34],"molecule":[35],"types":[36],"with":[37,89],"respect":[38],"their":[40,117],"receptor":[41,81,118],"binding":[42,70],"characteristics,":[43],"such":[44],"as":[45,107],"affinity":[46],"and":[47,129,136],"kinetic":[48],"binding/unbinding":[49],"rates.":[50],"In":[51],"this":[52],"study,":[53],"we":[54],"propose":[55],"a":[56,76,108],"practical":[57],"scheme":[59],"for":[60],"MC,":[61],"based":[64],"on":[65,82,146],"ligand-receptor":[69],"affinities.":[71],"This":[72],"method":[73],"requires":[74],"only":[75],"single":[77],"type":[78],"promiscuous":[80],"receiver":[84],"side,":[85],"capable":[86],"interacting":[88],"multiple":[90],"ligand":[91],"types.":[92],"We":[93,138],"analytically":[94],"derive":[95],"mean":[97],"Bit":[98],"Error":[99],"Probability":[100],"(BEP)":[101],"over":[102],"all":[103],"multiplexed":[104,127,150],"channels":[106],"function":[109],"similarity":[111],"among":[112],"ligands":[113],"terms":[115],"affinities,":[119],"number":[121,125],"receptors,":[123],"channels,":[128],"ratio":[131],"concentrations":[133],"encoding":[134],"bit-1":[135],"bit-0.":[137],"investigate":[139],"impact":[141],"each":[143],"design":[144],"parameter":[145],"performance":[148],"system.":[152]},"counts_by_year":[{"year":2023,"cited_by_count":1}],"updated_date":"2025-12-22T23:10:17.713674","created_date":"2025-10-10T00:00:00"}