{"id":"https://openalex.org/W1974169954","doi":"https://doi.org/10.1109/titb.2011.2181529","title":"A Novel Semiautomated Atherosclerotic Plaque Characterization Method Using Grayscale Intravascular Ultrasound Images: Comparison With Virtual Histology","display_name":"A Novel Semiautomated Atherosclerotic Plaque Characterization Method Using Grayscale Intravascular Ultrasound Images: Comparison With Virtual Histology","publication_year":2011,"publication_date":"2011-12-23","ids":{"openalex":"https://openalex.org/W1974169954","doi":"https://doi.org/10.1109/titb.2011.2181529","mag":"1974169954","pmid":"https://pubmed.ncbi.nlm.nih.gov/22203721"},"language":"en","primary_location":{"id":"doi:10.1109/titb.2011.2181529","is_oa":false,"landing_page_url":"https://doi.org/10.1109/titb.2011.2181529","pdf_url":null,"source":{"id":"https://openalex.org/S68937846","display_name":"IEEE Transactions on Information Technology in Biomedicine","issn_l":"1089-7771","issn":["1089-7771","1558-0032"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Information Technology in Biomedicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://zenodo.org/record/3435341","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056992421","display_name":"Lambros S. Athanasiou","orcid":"https://orcid.org/0000-0002-8029-1332"},"institutions":[{"id":"https://openalex.org/I194019607","display_name":"University of Ioannina","ror":"https://ror.org/01qg3j183","country_code":"GR","type":"education","lineage":["https://openalex.org/I194019607"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"L. S. Athanasiou","raw_affiliation_strings":["Department of Materials Science and Engineering, University of Ioannina, Ioannina, Greece. lmathanas@cc.uoi.gr","Dept. of Mater. Sci. & Eng., Univ. of Ioannina, Ioannina, Greece"],"affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, University of Ioannina, Ioannina, Greece. lmathanas@cc.uoi.gr","institution_ids":["https://openalex.org/I194019607"]},{"raw_affiliation_string":"Dept. of Mater. Sci. & Eng., Univ. of Ioannina, Ioannina, Greece","institution_ids":["https://openalex.org/I194019607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058278718","display_name":"Petros Karvelis","orcid":"https://orcid.org/0000-0002-0483-4868"},"institutions":[{"id":"https://openalex.org/I194019607","display_name":"University of Ioannina","ror":"https://ror.org/01qg3j183","country_code":"GR","type":"education","lineage":["https://openalex.org/I194019607"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"P. S. Karvelis","raw_affiliation_strings":["Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina (UoI), Ioannina, Greece","Dept. of Mater. Sci. & Eng., Univ. of Ioannina, Ioannina, Greece"],"affiliations":[{"raw_affiliation_string":"Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina (UoI), Ioannina, Greece","institution_ids":["https://openalex.org/I194019607"]},{"raw_affiliation_string":"Dept. of Mater. Sci. & Eng., Univ. of Ioannina, Ioannina, Greece","institution_ids":["https://openalex.org/I194019607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009035288","display_name":"Vassilis Tsakanikas","orcid":"https://orcid.org/0000-0002-2868-1720"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V. D. Tsakanikas","raw_affiliation_strings":["Biomedical Research Institute, FORTH, Ioannina, Greece","Biomed. Res. Inst.-FORTH, Ioannina, Greece"],"affiliations":[{"raw_affiliation_string":"Biomedical Research Institute, FORTH, Ioannina, Greece","institution_ids":[]},{"raw_affiliation_string":"Biomed. Res. Inst.-FORTH, Ioannina, Greece","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025715284","display_name":"Katerina \u039a. Naka","orcid":"https://orcid.org/0000-0002-9900-9659"},"institutions":[{"id":"https://openalex.org/I194019607","display_name":"University of Ioannina","ror":"https://ror.org/01qg3j183","country_code":"GR","type":"education","lineage":["https://openalex.org/I194019607"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"K. K. Naka","raw_affiliation_strings":["Michaelideion Cardiac Center, Department of Cardiology, Medical School, University of Ioannina (UoI), Ioannina, Greece","[Dept. of Cardiology, University of Ioannina, Ioannina, Greece]"],"affiliations":[{"raw_affiliation_string":"Michaelideion Cardiac Center, Department of Cardiology, Medical School, University of Ioannina (UoI), Ioannina, Greece","institution_ids":["https://openalex.org/I194019607"]},{"raw_affiliation_string":"[Dept. of Cardiology, University of Ioannina, Ioannina, Greece]","institution_ids":["https://openalex.org/I194019607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108123560","display_name":"Lampros K. Michalis","orcid":"https://orcid.org/0000-0001-8834-4462"},"institutions":[{"id":"https://openalex.org/I194019607","display_name":"University of Ioannina","ror":"https://ror.org/01qg3j183","country_code":"GR","type":"education","lineage":["https://openalex.org/I194019607"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"L. K. Michalis","raw_affiliation_strings":["Michaelideion Cardiac Center, Department of Cardiology, Medical School, University of Ioannina (UoI), Ioannina, Greece","[Dept. of Cardiology, University of Ioannina, Ioannina, Greece]"],"affiliations":[{"raw_affiliation_string":"Michaelideion Cardiac Center, Department of Cardiology, Medical School, University of Ioannina (UoI), Ioannina, Greece","institution_ids":["https://openalex.org/I194019607"]},{"raw_affiliation_string":"[Dept. of Cardiology, University of Ioannina, Ioannina, Greece]","institution_ids":["https://openalex.org/I194019607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050124666","display_name":"Christos V. Bourantas","orcid":"https://orcid.org/0000-0001-5319-1064"},"institutions":[{"id":"https://openalex.org/I2801269832","display_name":"Castle Hill Hospital","ror":"https://ror.org/042asnw05","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800043709","https://openalex.org/I2801269832"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"C. V. Bourantas","raw_affiliation_strings":["Department of Academic Cardiology, Castle Hill Hospital, East Yorkshire, UK","Dept. of Acad. Cardiology, Castle Hill Hosp., Cottingham, UK"],"affiliations":[{"raw_affiliation_string":"Department of Academic Cardiology, Castle Hill Hospital, East Yorkshire, UK","institution_ids":["https://openalex.org/I2801269832"]},{"raw_affiliation_string":"Dept. of Acad. Cardiology, Castle Hill Hosp., Cottingham, UK","institution_ids":["https://openalex.org/I2801269832"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057894101","display_name":"Dimitrios I. Fotiadis","orcid":"https://orcid.org/0000-0002-5987-9350"},"institutions":[{"id":"https://openalex.org/I194019607","display_name":"University of Ioannina","ror":"https://ror.org/01qg3j183","country_code":"GR","type":"education","lineage":["https://openalex.org/I194019607"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"D. I. Fotiadis","raw_affiliation_strings":["Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina (UoI), Ioannina, Greece","Dept. of Mater. Sci. & Eng., Univ. of Ioannina, Ioannina, Greece"],"affiliations":[{"raw_affiliation_string":"Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina (UoI), Ioannina, Greece","institution_ids":["https://openalex.org/I194019607"]},{"raw_affiliation_string":"Dept. of Mater. Sci. & Eng., Univ. of Ioannina, Ioannina, Greece","institution_ids":["https://openalex.org/I194019607"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5056992421"],"corresponding_institution_ids":["https://openalex.org/I194019607"],"apc_list":null,"apc_paid":null,"fwci":1.4723,"has_fulltext":false,"cited_by_count":42,"citation_normalized_percentile":{"value":0.81755279,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"16","issue":"3","first_page":"391","last_page":"400"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10727","display_name":"Ultrasound Imaging and Elastography","score":0.9919000267982483,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10816","display_name":"Cerebrovascular and Carotid Artery Diseases","score":0.9879999756813049,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intravascular-ultrasound","display_name":"Intravascular ultrasound","score":0.7201297879219055},{"id":"https://openalex.org/keywords/grayscale","display_name":"Grayscale","score":0.6994342803955078},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6163992881774902},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5847045183181763},{"id":"https://openalex.org/keywords/pixel","display_name":"Pixel","score":0.48602157831192017},{"id":"https://openalex.org/keywords/region-of-interest","display_name":"Region of interest","score":0.47911643981933594},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.42423075437545776},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.41170114278793335},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.33731716871261597},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.330845445394516},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2522277235984802}],"concepts":[{"id":"https://openalex.org/C2776931568","wikidata":"https://www.wikidata.org/wiki/Q1671577","display_name":"Intravascular ultrasound","level":2,"score":0.7201297879219055},{"id":"https://openalex.org/C78201319","wikidata":"https://www.wikidata.org/wiki/Q685727","display_name":"Grayscale","level":3,"score":0.6994342803955078},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6163992881774902},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5847045183181763},{"id":"https://openalex.org/C160633673","wikidata":"https://www.wikidata.org/wiki/Q355198","display_name":"Pixel","level":2,"score":0.48602157831192017},{"id":"https://openalex.org/C19609008","wikidata":"https://www.wikidata.org/wiki/Q2138203","display_name":"Region of interest","level":2,"score":0.47911643981933594},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.42423075437545776},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.41170114278793335},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.33731716871261597},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.330845445394516},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2522277235984802}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003663","descriptor_name":"Decision Trees","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003663","descriptor_name":"Decision Trees","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003663","descriptor_name":"Decision Trees","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006652","descriptor_name":"Histological Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006652","descriptor_name":"Histological Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006652","descriptor_name":"Histological Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018084","descriptor_name":"Ultrasonography, Interventional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018084","descriptor_name":"Ultrasonography, Interventional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018084","descriptor_name":"Ultrasonography, Interventional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058226","descriptor_name":"Plaque, Atherosclerotic","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D058226","descriptor_name":"Plaque, Atherosclerotic","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D058226","descriptor_name":"Plaque, Atherosclerotic","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D058226","descriptor_name":"Plaque, Atherosclerotic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D058226","descriptor_name":"Plaque, Atherosclerotic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D058226","descriptor_name":"Plaque, Atherosclerotic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/titb.2011.2181529","is_oa":false,"landing_page_url":"https://doi.org/10.1109/titb.2011.2181529","pdf_url":null,"source":{"id":"https://openalex.org/S68937846","display_name":"IEEE Transactions on Information Technology in Biomedicine","issn_l":"1089-7771","issn":["1089-7771","1558-0032"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Information Technology in Biomedicine","raw_type":"journal-article"},{"id":"pmid:22203721","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22203721","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society","raw_type":null},{"id":"pmh:oai:zenodo.org:3435341","is_oa":true,"landing_page_url":"https://zenodo.org/record/3435341","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:zenodo.org:3435341","is_oa":true,"landing_page_url":"https://zenodo.org/record/3435341","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/15","score":0.6600000262260437,"display_name":"Life in Land"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W147723833","https://openalex.org/W1486296693","https://openalex.org/W1502139799","https://openalex.org/W1557290961","https://openalex.org/W1663973292","https://openalex.org/W1977177161","https://openalex.org/W1992152105","https://openalex.org/W2002986652","https://openalex.org/W2005931379","https://openalex.org/W2047334981","https://openalex.org/W2058125218","https://openalex.org/W2060672892","https://openalex.org/W2080363053","https://openalex.org/W2085344137","https://openalex.org/W2086304126","https://openalex.org/W2089575713","https://openalex.org/W2094941678","https://openalex.org/W2104095591","https://openalex.org/W2109286340","https://openalex.org/W2109331709","https://openalex.org/W2112020699","https://openalex.org/W2118045195","https://openalex.org/W2119724493","https://openalex.org/W2119821739","https://openalex.org/W2120179549","https://openalex.org/W2124598893","https://openalex.org/W2163352848","https://openalex.org/W2168846437","https://openalex.org/W2170770739","https://openalex.org/W2172181482","https://openalex.org/W2302876338","https://openalex.org/W2412291070","https://openalex.org/W2480734025","https://openalex.org/W2594639291","https://openalex.org/W2911964244","https://openalex.org/W4239510810","https://openalex.org/W4249858935","https://openalex.org/W4256068510"],"related_works":["https://openalex.org/W586678879","https://openalex.org/W2478820723","https://openalex.org/W630410593","https://openalex.org/W304835647","https://openalex.org/W2349476719","https://openalex.org/W3140681711","https://openalex.org/W617755160","https://openalex.org/W1691631808","https://openalex.org/W1586320973","https://openalex.org/W2064771172"],"abstract_inverted_index":{"Intravascular":[0],"ultrasound":[1,20],"(IVUS)":[2],"virtual":[3,167],"histology":[4,168],"(VH-IVUS)":[5],"is":[6,89,106,117,134,186],"a":[7,74,92,113,130],"new":[8],"technique,":[9],"which":[10,36,56],"provides":[11],"automated":[12],"plaque":[13,75,100],"characterization":[14,76],"in":[15,48,82,126,193],"IVUS":[16,43,84,163],"frames,":[17],"using":[18],"the":[19,39,61,96,99,110,123,127,177,194],"backscattered":[21],"RF-signals.":[22],"However,":[23],"its":[24],"computation":[25],"can":[26,79],"only":[27],"be":[28,65,80,190],"performed":[29],"once":[30],"per":[31],"cardiac":[32],"cycle":[33],"(ECG-gated":[34],"technique),":[35],"significantly":[37],"decreases":[38],"number":[40],"of":[41,103,115,122,176],"characterized":[42],"frames.":[44],"Also":[45],"atherosclerotic":[46],"plaques":[47],"images":[49],"that":[50,78,183],"have":[51,72],"been":[52],"acquired":[53,165],"by":[54],"machines,":[55],"are":[57],"not":[58],"equipped":[59],"with":[60],"VH":[62],"software,":[63],"cannot":[64],"characterized.":[66],"To":[67],"address":[68],"these":[69,138],"limitations,":[70],"we":[71,160],"developed":[73],"technique":[77],"applied":[81],"grayscale":[83],"images.":[85],"Our":[86],"semiautomated":[87],"method":[88,179],"based":[90],"on":[91],"three-step":[93],"approach.":[94],"In":[95,109,152],"first":[97],"step,":[98,112,129],"area":[101],"[region":[102],"interest":[104],"(ROI)]":[105],"detected":[107],"semiautomatically.":[108],"second":[111],"set":[114],"features":[116],"extracted":[118],"for":[119],"each":[120],"pixel":[121],"ROI":[124],"and":[125,149,156,188,196],"third":[128],"random":[131],"forest":[132],"classifier":[133],"used":[135,161],"to":[136,154],"classify":[137],"pixels":[139],"into":[140],"four":[141],"classes:":[142],"dense":[143],"calcium,":[144],"necrotic":[145],"core,":[146],"fibrotic":[147],"tissue,":[148],"fibro-fatty":[150],"tissue.":[151],"order":[153],"train":[155],"validate":[157],"our":[158,184],"method,":[159],"300":[162],"frames":[164],"from":[166,170],"examinations":[169],"ten":[171],"patients.":[172],"The":[173],"overall":[174],"accuracy":[175],"proposed":[178],"was":[180],"85.65%":[181],"suggesting":[182],"approach":[185],"reliable":[187],"may":[189],"further":[191],"investigated":[192],"clinical":[195],"research":[197],"arena.":[198]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1}],"updated_date":"2026-03-09T08:58:05.943551","created_date":"2025-10-10T00:00:00"}