{"id":"https://openalex.org/W2170419021","doi":"https://doi.org/10.1109/titb.2007.903519","title":"A Semantic Grid Infrastructure Enabling Integrated Access and Analysis of Multilevel Biomedical Data in Support of Postgenomic Clinical Trials on Cancer","display_name":"A Semantic Grid Infrastructure Enabling Integrated Access and Analysis of Multilevel Biomedical Data in Support of Postgenomic Clinical Trials on Cancer","publication_year":2008,"publication_date":"2008-03-01","ids":{"openalex":"https://openalex.org/W2170419021","doi":"https://doi.org/10.1109/titb.2007.903519","mag":"2170419021","pmid":"https://pubmed.ncbi.nlm.nih.gov/18348950"},"language":"en","primary_location":{"id":"doi:10.1109/titb.2007.903519","is_oa":false,"landing_page_url":"https://doi.org/10.1109/titb.2007.903519","pdf_url":null,"source":{"id":"https://openalex.org/S68937846","display_name":"IEEE Transactions on Information Technology in Biomedicine","issn_l":"1089-7771","issn":["1089-7771","1558-0032"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Information Technology in Biomedicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087123353","display_name":"Manolis Tsiknakis","orcid":"https://orcid.org/0000-0001-8454-1450"},"institutions":[{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"M. Tsiknakis","raw_affiliation_strings":["Foundation for Research and Technology-Hellas, Institute of Computer Science, GR-71110 Heraklion, Greece. tsiknaki@ics.forth.gr","Foundation for Research and Technology Hellas, Institute for Computer Science, Heraklion, Greece"],"affiliations":[{"raw_affiliation_string":"Foundation for Research and Technology-Hellas, Institute of Computer Science, GR-71110 Heraklion, Greece. tsiknaki@ics.forth.gr","institution_ids":["https://openalex.org/I8901234"]},{"raw_affiliation_string":"Foundation for Research and Technology Hellas, Institute for Computer Science, Heraklion, Greece","institution_ids":["https://openalex.org/I8901234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047229883","display_name":"Mathias Brochhausen","orcid":"https://orcid.org/0000-0003-1834-3856"},"institutions":[{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Brochhausen","raw_affiliation_strings":["Institute of Formal Ontologies and Medical Information Science (IFOMIS), University of Saarland, Saarbruecken, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Formal Ontologies and Medical Information Science (IFOMIS), University of Saarland, Saarbruecken, Germany","institution_ids":["https://openalex.org/I91712215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009442343","display_name":"Jaros\u0142aw Nabrzyski","orcid":null},"institutions":[{"id":"https://openalex.org/I4210117901","display_name":"Poznan Supercomputing and Networking Center","ror":"https://ror.org/025cj6e44","country_code":"PL","type":"nonprofit","lineage":["https://openalex.org/I4210117901","https://openalex.org/I4210152414","https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"J. Nabrzyski","raw_affiliation_strings":["Poznan Supercomputing and Networking Center, Poznan, Poland"],"affiliations":[{"raw_affiliation_string":"Poznan Supercomputing and Networking Center, Poznan, Poland","institution_ids":["https://openalex.org/I4210117901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082058733","display_name":"J. Pucacki","orcid":null},"institutions":[{"id":"https://openalex.org/I4210117901","display_name":"Poznan Supercomputing and Networking Center","ror":"https://ror.org/025cj6e44","country_code":"PL","type":"nonprofit","lineage":["https://openalex.org/I4210117901","https://openalex.org/I4210152414","https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"J. Pucacki","raw_affiliation_strings":["Poznan Supercomputing and Networking Center, Poznan, Poland"],"affiliations":[{"raw_affiliation_string":"Poznan Supercomputing and Networking Center, Poznan, Poland","institution_ids":["https://openalex.org/I4210117901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012956979","display_name":"Stelios Sfakianakis","orcid":"https://orcid.org/0000-0001-8424-4157"},"institutions":[{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"S.G. Sfakianakis","raw_affiliation_strings":["Foundation for Research and Technology-Hellas, Institute of Computer Science and Institute of Molecular Biology and Biotechnology, Heraklion, Greece"],"affiliations":[{"raw_affiliation_string":"Foundation for Research and Technology-Hellas, Institute of Computer Science and Institute of Molecular Biology and Biotechnology, Heraklion, Greece","institution_ids":["https://openalex.org/I8901234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084193547","display_name":"George Potamias","orcid":"https://orcid.org/0000-0001-8129-4191"},"institutions":[{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"G. Potamias","raw_affiliation_strings":["Foundation for Research and Technology-Hellas, Institute of Computer Science and Institute of Molecular Biology and Biotechnology, Heraklion, Greece"],"affiliations":[{"raw_affiliation_string":"Foundation for Research and Technology-Hellas, Institute of Computer Science and Institute of Molecular Biology and Biotechnology, Heraklion, Greece","institution_ids":["https://openalex.org/I8901234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049771372","display_name":"Christine Desmedt","orcid":"https://orcid.org/0000-0002-5223-5579"},"institutions":[{"id":"https://openalex.org/I2801838318","display_name":"Institut Jules Bordet","ror":"https://ror.org/05e8s8534","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801838318"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"C. Desmedt","raw_affiliation_strings":["Functional Genomics and Translational Research Unit, Jules Bordet Institute, Brussels, Belgium"],"affiliations":[{"raw_affiliation_string":"Functional Genomics and Translational Research Unit, Jules Bordet Institute, Brussels, Belgium","institution_ids":["https://openalex.org/I2801838318"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044951417","display_name":"Dimitris Kafetzopoulos","orcid":"https://orcid.org/0000-0002-8086-0371"},"institutions":[{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"D. Kafetzopoulos","raw_affiliation_strings":["Foundation for Research and Technology-Hellas, Institute of Computer Science and Institute of Molecular Biology and Biotechnology, Heraklion, Greece"],"affiliations":[{"raw_affiliation_string":"Foundation for Research and Technology-Hellas, Institute of Computer Science and Institute of Molecular Biology and Biotechnology, Heraklion, Greece","institution_ids":["https://openalex.org/I8901234"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5087123353"],"corresponding_institution_ids":["https://openalex.org/I8901234"],"apc_list":null,"apc_paid":null,"fwci":5.1173,"has_fulltext":false,"cited_by_count":51,"citation_normalized_percentile":{"value":0.9625121,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"12","issue":"2","first_page":"205","last_page":"217"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11986","display_name":"Scientific Computing and Data Management","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/1802","display_name":"Information Systems and Management"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metadata","display_name":"Metadata","score":0.7839183807373047},{"id":"https://openalex.org/keywords/ontology","display_name":"Ontology","score":0.6879678964614868},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6815034747123718},{"id":"https://openalex.org/keywords/grid","display_name":"Grid","score":0.5218616724014282},{"id":"https://openalex.org/keywords/semantic-grid","display_name":"Semantic grid","score":0.4897499084472656},{"id":"https://openalex.org/keywords/clinical-trial","display_name":"Clinical trial","score":0.45571091771125793},{"id":"https://openalex.org/keywords/grid-computing","display_name":"Grid computing","score":0.4457458257675171},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.42102867364883423},{"id":"https://openalex.org/keywords/semantic-web","display_name":"Semantic Web","score":0.2731538414955139},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.18425709009170532},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.15470772981643677},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.09977000951766968}],"concepts":[{"id":"https://openalex.org/C93518851","wikidata":"https://www.wikidata.org/wiki/Q180160","display_name":"Metadata","level":2,"score":0.7839183807373047},{"id":"https://openalex.org/C25810664","wikidata":"https://www.wikidata.org/wiki/Q44325","display_name":"Ontology","level":2,"score":0.6879678964614868},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6815034747123718},{"id":"https://openalex.org/C187691185","wikidata":"https://www.wikidata.org/wiki/Q2020720","display_name":"Grid","level":2,"score":0.5218616724014282},{"id":"https://openalex.org/C103692084","wikidata":"https://www.wikidata.org/wiki/Q1765824","display_name":"Semantic grid","level":3,"score":0.4897499084472656},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.45571091771125793},{"id":"https://openalex.org/C70429105","wikidata":"https://www.wikidata.org/wiki/Q249999","display_name":"Grid computing","level":3,"score":0.4457458257675171},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.42102867364883423},{"id":"https://openalex.org/C2129575","wikidata":"https://www.wikidata.org/wiki/Q54837","display_name":"Semantic Web","level":2,"score":0.2731538414955139},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.18425709009170532},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15470772981643677},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.09977000951766968},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003299","descriptor_name":"Cooperative Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003299","descriptor_name":"Cooperative Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003299","descriptor_name":"Cooperative Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012660","descriptor_name":"Semantics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012660","descriptor_name":"Semantics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012660","descriptor_name":"Semantics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018511","descriptor_name":"Systems Integration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018511","descriptor_name":"Systems Integration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018511","descriptor_name":"Systems Integration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D033181","descriptor_name":"Information Dissemination","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D033181","descriptor_name":"Information Dissemination","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D033181","descriptor_name":"Information Dissemination","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1109/titb.2007.903519","is_oa":false,"landing_page_url":"https://doi.org/10.1109/titb.2007.903519","pdf_url":null,"source":{"id":"https://openalex.org/S68937846","display_name":"IEEE Transactions on Information Technology in Biomedicine","issn_l":"1089-7771","issn":["1089-7771","1558-0032"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Information Technology in Biomedicine","raw_type":"journal-article"},{"id":"pmid:18348950","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18348950","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.463.5571","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.463.5571","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.imbb.forth.gr/people/kafetzo/pdf/Publications/9.pdf","raw_type":"text"},{"id":"pmh:oai:dipot.ulb.ac.be:2013/153542","is_oa":false,"landing_page_url":"http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/153542","pdf_url":null,"source":{"id":"https://openalex.org/S4306401063","display_name":"D\u00e9p\u00f4t institutionnel de l'Universit\u00e9 libre de Bruxelles (Universit\u00e9 Libre de Bruxelles)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I132053463","host_organization_name":"Universit\u00e9 Libre de Bruxelles","host_organization_lineage":["https://openalex.org/I132053463"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE transactions on information technology in biomedicine, 12 (2","raw_type":"info:ulb-repo/semantics/openurl/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/9","display_name":"Industry, innovation and infrastructure","score":0.6299999952316284}],"awards":[],"funders":[{"id":"https://openalex.org/F4320306217","display_name":"Alliance for Cancer Gene Therapy","ror":"https://ror.org/00mms0j12"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W12633767","https://openalex.org/W70048713","https://openalex.org/W142986263","https://openalex.org/W173647602","https://openalex.org/W1501546233","https://openalex.org/W1523293200","https://openalex.org/W1546709038","https://openalex.org/W1552211698","https://openalex.org/W1555993967","https://openalex.org/W1557389692","https://openalex.org/W1968945485","https://openalex.org/W1985362378","https://openalex.org/W1999463736","https://openalex.org/W2004407704","https://openalex.org/W2042037135","https://openalex.org/W2047771918","https://openalex.org/W2070710170","https://openalex.org/W2074465378","https://openalex.org/W2076066161","https://openalex.org/W2077318760","https://openalex.org/W2091122332","https://openalex.org/W2099796212","https://openalex.org/W2105882193","https://openalex.org/W2110613589","https://openalex.org/W2128985829","https://openalex.org/W2132722663","https://openalex.org/W2137079713","https://openalex.org/W2139306864","https://openalex.org/W2139347953","https://openalex.org/W2147343434","https://openalex.org/W2152844712","https://openalex.org/W2153477637","https://openalex.org/W2157840751","https://openalex.org/W2163563958","https://openalex.org/W2166520171","https://openalex.org/W3148640261","https://openalex.org/W4212848460","https://openalex.org/W4238256486","https://openalex.org/W4285719527","https://openalex.org/W6602917394","https://openalex.org/W6605776017"],"related_works":["https://openalex.org/W2181389252","https://openalex.org/W169905258","https://openalex.org/W1824707887","https://openalex.org/W1503969631","https://openalex.org/W2147457882","https://openalex.org/W2978352833","https://openalex.org/W2103102902","https://openalex.org/W2114445820","https://openalex.org/W2169162452","https://openalex.org/W2116735528"],"abstract_inverted_index":{"This":[0,74],"paper":[1,75],"reports":[2],"on":[3,11,16,35,177],"original":[4],"results":[5],"of":[6,21,29,68,72,79,82,95,103,126,154,168,211],"the":[7,17,59,66,80,93,99,104,107,112,145,150,181,190,212],"Advancing":[8],"Clinico-Genomic":[9],"Trials":[10],"Cancer":[12],"integrated":[13],"project":[14,113],"focusing":[15],"design":[18,151],"and":[19,42,45,49,65,88,116,121,139,152,170,185,202],"development":[20,153],"a":[22,63,77,208],"European":[23],"biomedical":[24],"grid":[25,157],"infrastructure":[26],"in":[27,55,70,85,92],"support":[28],"multicentric,":[30],"postgenomic":[31,86],"clinical":[32,41,135],"trials":[33],"(CTs)":[34],"cancer.":[36],"Postgenomic":[37],"CTs":[38],"use":[39,167],"multilevel":[40],"genomic":[43],"data":[44,201],"advanced":[46],"computational":[47,203],"analysis":[48],"visualization":[50],"tools":[51],"to":[52,57,188],"test":[53],"hypothesis":[54],"trying":[56],"identify":[58],"molecular":[60],"reasons":[61],"for":[62,132],"disease":[64],"stratification":[67],"patients":[69],"terms":[71],"treatment.":[73],"provides":[76],"presentation":[78],"needs":[81,91],"users":[83],"involved":[84],"CTs,":[87],"presents":[89],"such":[90,127,163],"form":[94],"scenarios,":[96],"which":[97,194],"drive":[98],"requirements":[100],"engineering":[101],"phase":[102],"project.":[105],"Subsequently,":[106],"initial":[108],"architecture":[109],"specified":[110],"by":[111,180],"is":[114,159,183,205,216],"presented,":[115,184],"its":[117],"services":[118,128,158],"are":[119,129,172],"classified":[120],"discussed.":[122,160],"A":[123],"key":[124],"set":[125],"those":[130],"used":[131],"wrapping":[133],"heterogeneous":[134],"trial":[136],"management":[137],"systems":[138],"other":[140],"public":[141],"biological":[142],"databases.":[143],"Also,":[144],"main":[146],"technological":[147],"challenge,":[148],"i.e.":[149],"semantically":[155,196],"rich":[156,197],"In":[161],"achieving":[162],"an":[164],"objective,":[165],"extensive":[166],"ontologies":[169],"metadata":[171,192],"required.":[173],"The":[174],"Master":[175],"Ontology":[176],"Cancer,":[178],"developed":[179],"project,":[182],"our":[186],"approach":[187],"develop":[189],"required":[191],"registries,":[193],"provide":[195],"information":[198],"about":[199],"available":[200],"services,":[204],"provided.":[206],"Finally,":[207],"short":[209],"discussion":[210],"work":[213],"lying":[214],"ahead":[215],"included.":[217]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}