{"id":"https://openalex.org/W2888867330","doi":"https://doi.org/10.1109/tip.2018.2860255","title":"Automatic Segmentation of Retinal Layer in OCT Images With Choroidal Neovascularization","display_name":"Automatic Segmentation of Retinal Layer in OCT Images With Choroidal Neovascularization","publication_year":2018,"publication_date":"2018-07-26","ids":{"openalex":"https://openalex.org/W2888867330","doi":"https://doi.org/10.1109/tip.2018.2860255","mag":"2888867330","pmid":"https://pubmed.ncbi.nlm.nih.gov/30059302"},"language":"en","primary_location":{"id":"doi:10.1109/tip.2018.2860255","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tip.2018.2860255","pdf_url":null,"source":{"id":"https://openalex.org/S4210173141","display_name":"IEEE Transactions on Image Processing","issn_l":"1057-7149","issn":["1057-7149","1941-0042"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Image Processing","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031688232","display_name":"Dehui Xiang","orcid":"https://orcid.org/0000-0001-7873-9778"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Dehui Xiang","raw_affiliation_strings":["State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China","institution_ids":["https://openalex.org/I3923682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045518534","display_name":"Haihong Tian","orcid":"https://orcid.org/0000-0002-7052-9239"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haihong Tian","raw_affiliation_strings":["State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China","institution_ids":["https://openalex.org/I3923682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084505514","display_name":"Xiaoling Yang","orcid":"https://orcid.org/0000-0002-0403-852X"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoling Yang","raw_affiliation_strings":["State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China","institution_ids":["https://openalex.org/I3923682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048091475","display_name":"Fei Shi","orcid":"https://orcid.org/0000-0002-8878-6655"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fei Shi","raw_affiliation_strings":["State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China","institution_ids":["https://openalex.org/I3923682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058024483","display_name":"Weifang Zhu","orcid":"https://orcid.org/0000-0001-9540-4101"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weifang Zhu","raw_affiliation_strings":["State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China","institution_ids":["https://openalex.org/I3923682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100763973","display_name":"Haoyu Chen","orcid":"https://orcid.org/0000-0003-0676-4610"},"institutions":[{"id":"https://openalex.org/I32574673","display_name":"Shantou University","ror":"https://ror.org/01a099706","country_code":"CN","type":"education","lineage":["https://openalex.org/I32574673"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haoyu Chen","raw_affiliation_strings":["Joint Shantou International Eye Center, Shantou University, Shantou, China"],"affiliations":[{"raw_affiliation_string":"Joint Shantou International Eye Center, Shantou University, Shantou, China","institution_ids":["https://openalex.org/I32574673"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079807652","display_name":"Xinjian Chen","orcid":"https://orcid.org/0000-0002-0871-293X"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinjian Chen","raw_affiliation_strings":["State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, China","institution_ids":["https://openalex.org/I3923682"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5031688232"],"corresponding_institution_ids":["https://openalex.org/I3923682"],"apc_list":null,"apc_paid":null,"fwci":7.0089,"has_fulltext":false,"cited_by_count":65,"citation_normalized_percentile":{"value":0.97649004,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"27","issue":"12","first_page":"5880","last_page":"5891"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9921000003814697,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9891999959945679,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7398350834846497},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.7021675705909729},{"id":"https://openalex.org/keywords/optical-coherence-tomography","display_name":"Optical coherence tomography","score":0.6924059987068176},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.662901759147644},{"id":"https://openalex.org/keywords/macular-degeneration","display_name":"Macular degeneration","score":0.644951581954956},{"id":"https://openalex.org/keywords/retinal","display_name":"Retinal","score":0.5927372574806213},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5689327716827393},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.543790876865387},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.49909162521362305},{"id":"https://openalex.org/keywords/cut","display_name":"Cut","score":0.4484175443649292},{"id":"https://openalex.org/keywords/ophthalmology","display_name":"Ophthalmology","score":0.15812203288078308},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.09571745991706848}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7398350834846497},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.7021675705909729},{"id":"https://openalex.org/C2778818243","wikidata":"https://www.wikidata.org/wiki/Q899552","display_name":"Optical coherence tomography","level":2,"score":0.6924059987068176},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.662901759147644},{"id":"https://openalex.org/C2776403814","wikidata":"https://www.wikidata.org/wiki/Q27429789","display_name":"Macular degeneration","level":2,"score":0.644951581954956},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.5927372574806213},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5689327716827393},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.543790876865387},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.49909162521362305},{"id":"https://openalex.org/C5134670","wikidata":"https://www.wikidata.org/wiki/Q1626444","display_name":"Cut","level":4,"score":0.4484175443649292},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.15812203288078308},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.09571745991706848}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/tip.2018.2860255","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tip.2018.2860255","pdf_url":null,"source":{"id":"https://openalex.org/S4210173141","display_name":"IEEE Transactions on Image Processing","issn_l":"1057-7149","issn":["1057-7149","1941-0042"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Image Processing","raw_type":"journal-article"},{"id":"pmid:30059302","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30059302","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on image processing : a publication of the IEEE Signal Processing Society","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1437628622","display_name":null,"funder_award_id":"81401472","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2714381650","display_name":null,"funder_award_id":"81401451","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2782879477","display_name":null,"funder_award_id":"61401293","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7406829425","display_name":null,"funder_award_id":"2014CB748600","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G8587028467","display_name":null,"funder_award_id":"81371629","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8630419004","display_name":null,"funder_award_id":"61401294","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320310161","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1545791100","https://openalex.org/W1710476689","https://openalex.org/W1873693865","https://openalex.org/W1881919258","https://openalex.org/W1925219021","https://openalex.org/W1964869106","https://openalex.org/W1990889412","https://openalex.org/W2009195969","https://openalex.org/W2013107002","https://openalex.org/W2038850290","https://openalex.org/W2043670674","https://openalex.org/W2051578148","https://openalex.org/W2072086181","https://openalex.org/W2083181574","https://openalex.org/W2086295185","https://openalex.org/W2100546771","https://openalex.org/W2127318120","https://openalex.org/W2129534965","https://openalex.org/W2132830939","https://openalex.org/W2138157582","https://openalex.org/W2160226180","https://openalex.org/W2164774194","https://openalex.org/W2194775991","https://openalex.org/W2206167351","https://openalex.org/W2289913085","https://openalex.org/W2340171706","https://openalex.org/W2344912502","https://openalex.org/W2419784643","https://openalex.org/W2593233895","https://openalex.org/W2606534623","https://openalex.org/W2608854843","https://openalex.org/W2614500948","https://openalex.org/W2748622717","https://openalex.org/W2749433617","https://openalex.org/W2790408330","https://openalex.org/W2952426750","https://openalex.org/W2963446712","https://openalex.org/W2963703618","https://openalex.org/W4298289240","https://openalex.org/W6637568146","https://openalex.org/W6743194397","https://openalex.org/W6743446608"],"related_works":["https://openalex.org/W1014602304","https://openalex.org/W1033756233","https://openalex.org/W2109407305","https://openalex.org/W2032319136","https://openalex.org/W2897997384","https://openalex.org/W2088651901","https://openalex.org/W1544828638","https://openalex.org/W2086619084","https://openalex.org/W2000036183","https://openalex.org/W2049858394"],"abstract_inverted_index":{"Age-related":[0],"macular":[1,144],"degeneration":[2],"is":[3,46,110],"one":[4],"of":[5,9,15,28,74,120],"the":[6,12,26,37,67,123,151],"main":[7],"causes":[8],"blindness.":[10],"However,":[11],"internal":[13],"structures":[14],"retinas":[16],"are":[17,64,103,125],"complex":[18],"and":[19,52,60,87,94,98],"difficult":[20],"to":[21,25,113],"be":[22,83],"recognized":[23],"due":[24],"occurrence":[27],"neovascularization.":[29,53],"Traditional":[30],"surface":[31],"detection":[32,101],"methods":[33],"may":[34],"fail":[35],"in":[36,122],"layer":[38,100],"segmentation.":[39],"In":[40],"this":[41],"paper,":[42],"a":[43],"supervised":[44],"method":[45,134,153],"reported":[47],"for":[48,66],"simultaneously":[49],"segmenting":[50],"layers":[51,90],"Three":[54],"spatial":[55],"features,":[56,59],"seven":[57],"gray-level-based":[58],"14":[61],"layer-like":[62,130],"features":[63],"extracted":[65],"neural":[68],"network":[69],"classifier.":[70],"The":[71,118,132,146],"coarse":[72],"surfaces":[73],"different":[75,92],"optical":[76],"coherence":[77],"tomography":[78],"(OCT)":[79],"images":[80,141],"can":[81],"thus":[82],"found.":[84],"To":[85],"describe":[86],"enhance":[88],"retinal":[89,116],"with":[91,142],"thicknesses":[93],"abnormalities,":[95],"multi-scale":[96],"bright":[97],"dark":[99],"filters":[102],"introduced.":[104],"A":[105],"constrained":[106],"graph":[107,124],"search":[108],"algorithm":[109],"also":[111],"proposed":[112,133,152],"accurately":[114],"detect":[115],"surfaces.":[117],"weights":[119],"nodes":[121],"computed":[126],"based":[127],"on":[128,137],"these":[129],"responses.":[131],"was":[135],"evaluated":[136],"42":[138],"spectral-domain":[139],"OCT":[140],"age-related":[143],"degeneration.":[145],"experimental":[147],"results":[148],"show":[149],"that":[150],"outperforms":[154],"state-of-the-art":[155],"methods.":[156]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":1}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}