{"id":"https://openalex.org/W4412722614","doi":"https://doi.org/10.1109/tim.2025.3593540","title":"Cycle-PSFCNN: A Two-Stage Defocus Reasoning and Restoration Network for Microfluidic Systems","display_name":"Cycle-PSFCNN: A Two-Stage Defocus Reasoning and Restoration Network for Microfluidic Systems","publication_year":2025,"publication_date":"2025-01-01","ids":{"openalex":"https://openalex.org/W4412722614","doi":"https://doi.org/10.1109/tim.2025.3593540"},"language":"en","primary_location":{"id":"doi:10.1109/tim.2025.3593540","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tim.2025.3593540","pdf_url":null,"source":{"id":"https://openalex.org/S10892749","display_name":"IEEE Transactions on Instrumentation and Measurement","issn_l":"0018-9456","issn":["0018-9456","1557-9662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Instrumentation and Measurement","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077287089","display_name":"Qiushu Chen","orcid":"https://orcid.org/0000-0002-5679-2188"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210100356","display_name":"Ministry of Education","ror":"https://ror.org/018f7hf93","country_code":"CL","type":"government","lineage":["https://openalex.org/I4210100356"]}],"countries":["CL","CN"],"is_corresponding":true,"raw_author_name":"Qiushu Chen","raw_affiliation_strings":["Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I4210100356"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yuzhe Liu","orcid":"https://orcid.org/0009-0003-2775-8700"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210100356","display_name":"Ministry of Education","ror":"https://ror.org/018f7hf93","country_code":"CL","type":"government","lineage":["https://openalex.org/I4210100356"]}],"countries":["CL","CN"],"is_corresponding":false,"raw_author_name":"Yuzhe Liu","raw_affiliation_strings":["Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I4210100356"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101626936","display_name":"Xuan Zhao","orcid":"https://orcid.org/0000-0001-8517-0276"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuan Zhao","raw_affiliation_strings":["Academy for Engineering and Technology, Fudan University, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Academy for Engineering and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100730191","display_name":"Liwen Chen","orcid":"https://orcid.org/0000-0002-7271-2467"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210100356","display_name":"Ministry of Education","ror":"https://ror.org/018f7hf93","country_code":"CL","type":"government","lineage":["https://openalex.org/I4210100356"]}],"countries":["CL","CN"],"is_corresponding":false,"raw_author_name":"Liwen Chen","raw_affiliation_strings":["Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I4210100356"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070458178","display_name":"Chongjun Ma","orcid":null},"institutions":[{"id":"https://openalex.org/I4210159344","display_name":"Viva Biotech (China)","ror":"https://ror.org/05p50vw42","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210159344"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chongjun Ma","raw_affiliation_strings":["Drug Product Development Department, Shanghai Henlius Biotech Inc., Shanghai, China","Drug Product Development Department, Shanghai Henlius Biotech, Inc, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Drug Product Development Department, Shanghai Henlius Biotech Inc., Shanghai, China","institution_ids":["https://openalex.org/I4210159344"]},{"raw_affiliation_string":"Drug Product Development Department, Shanghai Henlius Biotech, Inc, Shanghai, China","institution_ids":["https://openalex.org/I4210159344"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zhijun Zhang","orcid":"https://orcid.org/0009-0001-2076-5663"},"institutions":[{"id":"https://openalex.org/I4210147972","display_name":"MKS Instruments (Japan)","ror":"https://ror.org/03wfqxa90","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210092805","https://openalex.org/I4210147972"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Zhijun Zhang","raw_affiliation_strings":["Scientific Instruments, DKSH Technology, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Scientific Instruments, DKSH Technology, Shanghai, China","institution_ids":["https://openalex.org/I4210147972"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019940896","display_name":"Ruijiao Li","orcid":"https://orcid.org/0000-0002-3191-3828"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruijiao Li","raw_affiliation_strings":["Academy for Engineering and Technology, Fudan University, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Academy for Engineering and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078269576","display_name":"Lan Mi","orcid":"https://orcid.org/0000-0002-2320-2225"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210100356","display_name":"Ministry of Education","ror":"https://ror.org/018f7hf93","country_code":"CL","type":"government","lineage":["https://openalex.org/I4210100356"]}],"countries":["CL","CN"],"is_corresponding":false,"raw_author_name":"Lan Mi","raw_affiliation_strings":["Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I4210100356"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044855414","display_name":"Yiyan Fei","orcid":"https://orcid.org/0000-0002-2413-130X"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210100356","display_name":"Ministry of Education","ror":"https://ror.org/018f7hf93","country_code":"CL","type":"government","lineage":["https://openalex.org/I4210100356"]}],"countries":["CL","CN"],"is_corresponding":false,"raw_author_name":"Yiyan Fei","raw_affiliation_strings":["Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I4210100356"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110301590","display_name":"Huiliang Shang","orcid":"https://orcid.org/0000-0002-9553-1589"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huiliang Shang","raw_affiliation_strings":["School of Information Science and Technology, Fudan University, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"School of Information Science and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Dongmei Han","orcid":"https://orcid.org/0009-0008-5137-0681"},"institutions":[{"id":"https://openalex.org/I4210159344","display_name":"Viva Biotech (China)","ror":"https://ror.org/05p50vw42","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210159344"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dongmei Han","raw_affiliation_strings":["Drug Product Development Department, Shanghai Henlius Biotech Inc., Shanghai, China","Drug Product Development Department, Shanghai Henlius Biotech, Inc, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Drug Product Development Department, Shanghai Henlius Biotech Inc., Shanghai, China","institution_ids":["https://openalex.org/I4210159344"]},{"raw_affiliation_string":"Drug Product Development Department, Shanghai Henlius Biotech, Inc, Shanghai, China","institution_ids":["https://openalex.org/I4210159344"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074838630","display_name":"Jiong Ma","orcid":"https://orcid.org/0000-0003-3632-4624"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210100356","display_name":"Ministry of Education","ror":"https://ror.org/018f7hf93","country_code":"CL","type":"government","lineage":["https://openalex.org/I4210100356"]}],"countries":["CL","CN"],"is_corresponding":false,"raw_author_name":"Jiong Ma","raw_affiliation_strings":["Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China"],"affiliations":[{"raw_affiliation_string":"Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I4210100356"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5077287089"],"corresponding_institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210100356"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.25277314,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"74","issue":null,"first_page":"1","last_page":"14"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.958299994468689,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12452","display_name":"Electrowetting and Microfluidic Technologies","score":0.939300000667572,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.6197149157524109},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5480478405952454},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.21085768938064575},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.16255950927734375}],"concepts":[{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.6197149157524109},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5480478405952454},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.21085768938064575},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.16255950927734375}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/tim.2025.3593540","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tim.2025.3593540","pdf_url":null,"source":{"id":"https://openalex.org/S10892749","display_name":"IEEE Transactions on Instrumentation and Measurement","issn_l":"0018-9456","issn":["0018-9456","1557-9662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Instrumentation and Measurement","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/15","score":0.4099999964237213,"display_name":"Life in Land"}],"awards":[{"id":"https://openalex.org/G1867520023","display_name":null,"funder_award_id":"32271510","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5148114150","display_name":null,"funder_award_id":"62175036","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5273798321","display_name":null,"funder_award_id":"62175034","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W2122651297","https://openalex.org/W2141955292","https://openalex.org/W2790594255","https://openalex.org/W2884585870","https://openalex.org/W2891158090","https://openalex.org/W2910897194","https://openalex.org/W2962793481","https://openalex.org/W2963073614","https://openalex.org/W2965427761","https://openalex.org/W2982795046","https://openalex.org/W3007990071","https://openalex.org/W3017220821","https://openalex.org/W3026309659","https://openalex.org/W3035504497","https://openalex.org/W3037300642","https://openalex.org/W3041148285","https://openalex.org/W3047237378","https://openalex.org/W3112598205","https://openalex.org/W3173667207","https://openalex.org/W3180322328","https://openalex.org/W3204971388","https://openalex.org/W3212022416","https://openalex.org/W4200101273","https://openalex.org/W4220694560","https://openalex.org/W4220798619","https://openalex.org/W4223483730","https://openalex.org/W4225269970","https://openalex.org/W4226266309","https://openalex.org/W4282046443","https://openalex.org/W4288052579","https://openalex.org/W4290375470","https://openalex.org/W4294992465","https://openalex.org/W4311923563","https://openalex.org/W4316660751","https://openalex.org/W4379056571","https://openalex.org/W4382934793","https://openalex.org/W4385360935","https://openalex.org/W4387229378","https://openalex.org/W4393140498","https://openalex.org/W4394764020"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W3103016203","https://openalex.org/W2106238498","https://openalex.org/W2463681241","https://openalex.org/W161520385","https://openalex.org/W97203997","https://openalex.org/W2624661525","https://openalex.org/W1572874849"],"abstract_inverted_index":{"There":[0],"is":[1,65,137],"an":[2],"issue":[3],"in":[4,26,36,115],"microfluidic":[5,122],"systems":[6,41,71,123],"where":[7],"particles":[8,25],"become":[9],"out-of-focus":[10],"during":[11],"imaging":[12],"due":[13],"to":[14,44,76,89],"excessively":[15],"wide":[16],"flow":[17],"channels,":[18],"which":[19],"interferes":[20],"with":[21,79],"the":[22,27,34,46,49,56,68,77,129],"detection":[23,35],"of":[24,58],"pharmaceutical":[28],"manufacturing":[29],"process,":[30],"as":[31,33],"well":[32],"biochemical":[37],"analysis.":[38],"Deep":[39],"learning":[40],"are":[42],"necessary":[43],"do":[45],"restoration.":[47],"However,":[48],"traditional":[50],"defocus":[51,134],"coefficient":[52],"predicting":[53],"networks":[54],"require":[55],"aid":[57],"deconvolution":[59],"operation,":[60],"whose":[61],"texture":[62],"restoration":[63,84,100],"capability":[64],"limited;":[66],"while":[67],"end-to-end":[69],"GAN":[70],"introduce":[72],"distortion":[73],"and":[74,98,109,112,118],"artifacts":[75],"images":[78],"weak":[80],"interpretability.":[81],"A":[82],"two-step":[83],"network,":[85],"Cycle-PSFCNN,":[86],"was":[87,104],"proposed":[88],"combine":[90],"those":[91],"two":[92],"tasks,":[93],"forming":[94],"a":[95],"more":[96,125],"robust":[97],"interpretable":[99],"process.":[101],"The":[102],"network":[103],"evaluated":[105],"on":[106],"both":[107],"simulation":[108],"real-world":[110],"datasets,":[111],"its":[113],"applications":[114],"particle":[116],"counting":[117],"size":[119],"statistics":[120],"helped":[121],"achieve":[124],"accurate":[126],"results,":[127],"reducing":[128],"statistical":[130],"errors":[131],"caused":[132],"by":[133],"blur.":[135],"Code":[136],"available":[138],"at":[139],"https://github.com/qiushu-chen/Cycle-PSFCNN.":[140]},"counts_by_year":[],"updated_date":"2026-04-09T08:11:56.329763","created_date":"2025-10-10T00:00:00"}
