{"id":"https://openalex.org/W4410086689","doi":"https://doi.org/10.1109/tim.2025.3566713","title":"Label-Free In Situ Detection of DNA Hybridization Based on Long-Range Surface Plasmon Resonance in Microstructured Optical Fiber","display_name":"Label-Free In Situ Detection of DNA Hybridization Based on Long-Range Surface Plasmon Resonance in Microstructured Optical Fiber","publication_year":2025,"publication_date":"2025-01-01","ids":{"openalex":"https://openalex.org/W4410086689","doi":"https://doi.org/10.1109/tim.2025.3566713"},"language":"en","primary_location":{"id":"doi:10.1109/tim.2025.3566713","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tim.2025.3566713","pdf_url":null,"source":{"id":"https://openalex.org/S10892749","display_name":"IEEE Transactions on Instrumentation and Measurement","issn_l":"0018-9456","issn":["0018-9456","1557-9662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Instrumentation and Measurement","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075171056","display_name":"Zhigang Gao","orcid":"https://orcid.org/0000-0002-1746-7382"},"institutions":[{"id":"https://openalex.org/I169351748","display_name":"Bengbu Medical College","ror":"https://ror.org/01f8qvj05","country_code":"CN","type":"education","lineage":["https://openalex.org/I169351748"]},{"id":"https://openalex.org/I39333907","display_name":"Yanshan University","ror":"https://ror.org/02txfnf15","country_code":"CN","type":"education","lineage":["https://openalex.org/I39333907"]},{"id":"https://openalex.org/I4400573172","display_name":"Bengbu University","ror":"https://ror.org/05p8d2v16","country_code":null,"type":"education","lineage":["https://openalex.org/I4400573172"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhigang Gao","raw_affiliation_strings":["State Key Laboratory of Metastable Materials Science and Technology and Hebei Key Laboratory of Microstructural Material Physics, School of Science, Yanshan University, Qinhuangdao, China","School of Mathematics and Physics, Bengbu University, Bengbu, China"],"raw_orcid":"https://orcid.org/0000-0002-1746-7382","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Metastable Materials Science and Technology and Hebei Key Laboratory of Microstructural Material Physics, School of Science, Yanshan University, Qinhuangdao, China","institution_ids":["https://openalex.org/I39333907"]},{"raw_affiliation_string":"School of Mathematics and Physics, Bengbu University, Bengbu, China","institution_ids":["https://openalex.org/I169351748","https://openalex.org/I4400573172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085777661","display_name":"Ruyue Shi","orcid":"https://orcid.org/0000-0003-2495-1444"},"institutions":[{"id":"https://openalex.org/I39333907","display_name":"Yanshan University","ror":"https://ror.org/02txfnf15","country_code":"CN","type":"education","lineage":["https://openalex.org/I39333907"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruyue Shi","raw_affiliation_strings":["State Key Laboratory of Metastable Materials Science and Technology and Hebei Key Laboratory of Microstructural Material Physics, School of Science, Yanshan University, Qinhuangdao, China","School of Science, State Key Laboratory of Metastable Materials Science &#x0026; Technology and Key Laboratory for Microstructural Material Physics of Hebei Province, Yanshan University, Qinhuangdao, PR China"],"raw_orcid":"https://orcid.org/0000-0003-2495-1444","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Metastable Materials Science and Technology and Hebei Key Laboratory of Microstructural Material Physics, School of Science, Yanshan University, Qinhuangdao, China","institution_ids":["https://openalex.org/I39333907"]},{"raw_affiliation_string":"School of Science, State Key Laboratory of Metastable Materials Science &#x0026; Technology and Key Laboratory for Microstructural Material Physics of Hebei Province, Yanshan University, Qinhuangdao, PR China","institution_ids":["https://openalex.org/I39333907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072197700","display_name":"Hailiang Chen","orcid":"https://orcid.org/0000-0002-5802-2670"},"institutions":[{"id":"https://openalex.org/I39333907","display_name":"Yanshan University","ror":"https://ror.org/02txfnf15","country_code":"CN","type":"education","lineage":["https://openalex.org/I39333907"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hailiang Chen","raw_affiliation_strings":["State Key Laboratory of Metastable Materials Science and Technology and Hebei Key Laboratory of Microstructural Material Physics, School of Science, Yanshan University, Qinhuangdao, China","School of Science, State Key Laboratory of Metastable Materials Science &#x0026; Technology and Key Laboratory for Microstructural Material Physics of Hebei Province, Yanshan University, Qinhuangdao, PR China"],"raw_orcid":"https://orcid.org/0000-0002-5802-2670","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Metastable Materials Science and Technology and Hebei Key Laboratory of Microstructural Material Physics, School of Science, Yanshan University, Qinhuangdao, China","institution_ids":["https://openalex.org/I39333907"]},{"raw_affiliation_string":"School of Science, State Key Laboratory of Metastable Materials Science &#x0026; Technology and Key Laboratory for Microstructural Material Physics of Hebei Province, Yanshan University, Qinhuangdao, PR China","institution_ids":["https://openalex.org/I39333907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014684738","display_name":"Lida Li","orcid":"https://orcid.org/0000-0001-9386-194X"},"institutions":[{"id":"https://openalex.org/I39333907","display_name":"Yanshan University","ror":"https://ror.org/02txfnf15","country_code":"CN","type":"education","lineage":["https://openalex.org/I39333907"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lida Li","raw_affiliation_strings":["State Key Laboratory of Metastable Materials Science and Technology and Hebei Key Laboratory of Microstructural Material Physics, School of Science, Yanshan University, Qinhuangdao, China","School of Science, State Key Laboratory of Metastable Materials Science &#x0026; Technology and Key Laboratory for Microstructural Material Physics of Hebei Province, Yanshan University, Qinhuangdao, PR China"],"raw_orcid":"https://orcid.org/0000-0001-9386-194X","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Metastable Materials Science and Technology and Hebei Key Laboratory of Microstructural Material Physics, School of Science, Yanshan University, Qinhuangdao, China","institution_ids":["https://openalex.org/I39333907"]},{"raw_affiliation_string":"School of Science, State Key Laboratory of Metastable Materials Science &#x0026; Technology and Key Laboratory for Microstructural Material Physics of Hebei Province, Yanshan University, Qinhuangdao, PR China","institution_ids":["https://openalex.org/I39333907"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.8506,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.85231346,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"74","issue":null,"first_page":"1","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10205","display_name":"Advanced Fiber Optic Sensors","score":0.9686999917030334,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10205","display_name":"Advanced Fiber Optic Sensors","score":0.9686999917030334,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.9648000001907349,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.9602000117301941,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.6516185998916626},{"id":"https://openalex.org/keywords/surface-plasmon-resonance","display_name":"Surface plasmon resonance","score":0.6223598122596741},{"id":"https://openalex.org/keywords/optical-fiber","display_name":"Optical fiber","score":0.5821526050567627},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.48649805784225464},{"id":"https://openalex.org/keywords/surface-plasmon","display_name":"Surface plasmon","score":0.48558276891708374},{"id":"https://openalex.org/keywords/in-situ","display_name":"In situ","score":0.4479061961174011},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.44117286801338196},{"id":"https://openalex.org/keywords/resonance","display_name":"Resonance (particle physics)","score":0.4383932948112488},{"id":"https://openalex.org/keywords/photonic-crystal-fiber","display_name":"Photonic-crystal fiber","score":0.41550391912460327},{"id":"https://openalex.org/keywords/plasmon","display_name":"Plasmon","score":0.41408416628837585},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.19630011916160583},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.1680450439453125},{"id":"https://openalex.org/keywords/nanoparticle","display_name":"Nanoparticle","score":0.13423943519592285}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6516185998916626},{"id":"https://openalex.org/C106847996","wikidata":"https://www.wikidata.org/wiki/Q898756","display_name":"Surface plasmon resonance","level":3,"score":0.6223598122596741},{"id":"https://openalex.org/C194232370","wikidata":"https://www.wikidata.org/wiki/Q162","display_name":"Optical fiber","level":2,"score":0.5821526050567627},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.48649805784225464},{"id":"https://openalex.org/C136676167","wikidata":"https://www.wikidata.org/wiki/Q1151829","display_name":"Surface plasmon","level":3,"score":0.48558276891708374},{"id":"https://openalex.org/C2777822432","wikidata":"https://www.wikidata.org/wiki/Q216681","display_name":"In situ","level":2,"score":0.4479061961174011},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.44117286801338196},{"id":"https://openalex.org/C139210041","wikidata":"https://www.wikidata.org/wiki/Q2145840","display_name":"Resonance (particle physics)","level":2,"score":0.4383932948112488},{"id":"https://openalex.org/C107157254","wikidata":"https://www.wikidata.org/wiki/Q1256244","display_name":"Photonic-crystal fiber","level":3,"score":0.41550391912460327},{"id":"https://openalex.org/C110879396","wikidata":"https://www.wikidata.org/wiki/Q58392","display_name":"Plasmon","level":2,"score":0.41408416628837585},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.19630011916160583},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1680450439453125},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.13423943519592285},{"id":"https://openalex.org/C109214941","wikidata":"https://www.wikidata.org/wiki/Q18334","display_name":"Particle physics","level":1,"score":0.0},{"id":"https://openalex.org/C153294291","wikidata":"https://www.wikidata.org/wiki/Q25261","display_name":"Meteorology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/tim.2025.3566713","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tim.2025.3566713","pdf_url":null,"source":{"id":"https://openalex.org/S10892749","display_name":"IEEE Transactions on Instrumentation and Measurement","issn_l":"0018-9456","issn":["0018-9456","1557-9662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Instrumentation and Measurement","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1425157251","display_name":null,"funder_award_id":"12074331","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3030164063","display_name":null,"funder_award_id":"F2021203112","funder_id":"https://openalex.org/F4320322163","funder_display_name":"Natural Science Foundation of Hebei Province"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322163","display_name":"Natural Science Foundation of Hebei Province","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1655364877","https://openalex.org/W2009415312","https://openalex.org/W2010425546","https://openalex.org/W2048702576","https://openalex.org/W2135032572","https://openalex.org/W2143540147","https://openalex.org/W2273887968","https://openalex.org/W2326158222","https://openalex.org/W2327610826","https://openalex.org/W2342556404","https://openalex.org/W2580939229","https://openalex.org/W2606668296","https://openalex.org/W2735577419","https://openalex.org/W2763998334","https://openalex.org/W2910752065","https://openalex.org/W2930472942","https://openalex.org/W2991388975","https://openalex.org/W3004744434","https://openalex.org/W3007834429","https://openalex.org/W3046504233","https://openalex.org/W3108312350","https://openalex.org/W3110460611","https://openalex.org/W3134974945","https://openalex.org/W3158385814","https://openalex.org/W3205932325","https://openalex.org/W4210689493","https://openalex.org/W4282029464","https://openalex.org/W4313312550","https://openalex.org/W4316661138","https://openalex.org/W4327919971","https://openalex.org/W4362591299","https://openalex.org/W4388595195","https://openalex.org/W4396853223","https://openalex.org/W4396877492","https://openalex.org/W4396877639"],"related_works":["https://openalex.org/W4366991816","https://openalex.org/W3141447964","https://openalex.org/W2032954477","https://openalex.org/W2775150149","https://openalex.org/W2013682213","https://openalex.org/W2090877574","https://openalex.org/W1533020838","https://openalex.org/W2098412915","https://openalex.org/W2044592186","https://openalex.org/W2897594299"],"abstract_inverted_index":{"Deoxyribonucleic":[0],"acid":[1],"(DNA),":[2],"which":[3,93],"is":[4,28],"considered":[5],"to":[6,12,30,33,61,75,85,96,112,122,137,152],"be":[7,173],"the":[8,38,63,77,87,98,124,131,138,153,161],"gene":[9],"code":[10],"relating":[11],"some":[13],"serious":[14],"diseases":[15],"such":[16],"as":[17],"breast":[18],"cancer,":[19,21,27],"lymph":[20],"leukemia,":[22],"intestinal":[23],"cancer":[24],"and":[25,84,114,169],"lung":[26],"difficult":[29],"detect":[31,62,97],"due":[32],"its":[34],"low":[35,64],"concentration":[36,65,145],"in":[37,108,177],"early":[39],"stage":[40],"of":[41,51,70,80,101,146,163],"diseases.":[42],"In":[43],"this":[44],"paper,":[45],"we":[46],"propose":[47],"a":[48,174],"composite":[49,104],"film":[50,69],"Au/MgF<sub":[52],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[53,72],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">2</sub>":[54,73],"coated":[55],"pomelo-type":[56],"microstructured":[57],"optical":[58],"fiber":[59],"(MOF)":[60],"DNA.":[66,102],"The":[67,103,157],"dielectric":[68],"MgF<sub":[71],"helped":[74],"enhance":[76],"penetration":[78],"depth":[79],"surface":[81,89],"plasmon":[82,90],"polaritons":[83],"achieve":[86],"long-range":[88],"resonance":[91],"(LRSPR)":[92],"was":[94,135],"utilized":[95],"micron-size":[99],"molecule":[100],"film-coated":[105],"MOF":[106],"immersed":[107],"mercaptoethylamine":[109],"(MEA)":[110],"solution":[111],"aminate":[113],"then":[115],"functionalized":[116],"with":[117,142],"COOH-modified":[118],"probe":[119,134],"DNA":[120,140,155,178],"(pDNA)":[121],"fabricate":[123],"sensing":[125,133],"probe.":[126],"Experimental":[127],"results":[128],"showed":[129],"that":[130],"fabricated":[132],"sensitive":[136],"target":[139],"(tDNA)":[141],"an":[143],"ultra-low":[144],"2":[147],"\u03bc":[148],"M,":[149],"but":[150],"insensitive":[151],"non-target":[154],"(nonDNA).":[156],"proposed":[158],"sensor,":[159],"showing":[160],"merits":[162],"label-free,":[164],"in-situ,":[165],"real-time,":[166],"specificity,":[167],"stability,":[168],"high":[170],"sensitivity,":[171],"could":[172],"competitive":[175],"candidate":[176],"detection.":[179]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}
