{"id":"https://openalex.org/W3140530748","doi":"https://doi.org/10.1109/tim.2021.3066469","title":"Evaluation of Cerebral Tissue Oximeters Using Multilayered Dynamic Head Models","display_name":"Evaluation of Cerebral Tissue Oximeters Using Multilayered Dynamic Head Models","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3140530748","doi":"https://doi.org/10.1109/tim.2021.3066469","mag":"3140530748"},"language":"en","primary_location":{"id":"doi:10.1109/tim.2021.3066469","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tim.2021.3066469","pdf_url":null,"source":{"id":"https://openalex.org/S10892749","display_name":"IEEE Transactions on Instrumentation and Measurement","issn_l":"0018-9456","issn":["0018-9456","1557-9662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Instrumentation and Measurement","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032135106","display_name":"Meltem \u0130zzeto\u011flu","orcid":"https://orcid.org/0000-0002-1768-3384"},"institutions":[{"id":"https://openalex.org/I7863295","display_name":"Villanova University","ror":"https://ror.org/02g7kd627","country_code":"US","type":"education","lineage":["https://openalex.org/I7863295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Meltem Izzetoglu","raw_affiliation_strings":["Electrical and Computer Engineering Department, Villanova University, Villanova, PA, USA"],"raw_orcid":"https://orcid.org/0000-0002-1768-3384","affiliations":[{"raw_affiliation_string":"Electrical and Computer Engineering Department, Villanova University, Villanova, PA, USA","institution_ids":["https://openalex.org/I7863295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009294693","display_name":"Kambiz Pourrezaei","orcid":"https://orcid.org/0000-0002-6031-2669"},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kambiz Pourrezaei","raw_affiliation_strings":["School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, PA, USA"],"raw_orcid":"https://orcid.org/0000-0002-6031-2669","affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I72816309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100412673","display_name":"Juan Du","orcid":"https://orcid.org/0000-0002-7978-0665"},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Juan Du","raw_affiliation_strings":["School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, PA, USA"],"raw_orcid":"https://orcid.org/0000-0002-7978-0665","affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I72816309"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012896273","display_name":"Patricia A. Shewokis","orcid":"https://orcid.org/0000-0001-9246-9495"},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patricia A. Shewokis","raw_affiliation_strings":["Nutrition Sciences Department, College of Nursing and Health Professions, Drexel University, Philadelphia, PA, USA","School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA, USA"],"raw_orcid":"https://orcid.org/0000-0001-9246-9495","affiliations":[{"raw_affiliation_string":"Nutrition Sciences Department, College of Nursing and Health Professions, Drexel University, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I72816309"]},{"raw_affiliation_string":"School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I72816309"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9846,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.74779691,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"70","issue":null,"first_page":"1","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11196","display_name":"Non-Invasive Vital Sign Monitoring","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/imaging-phantom","display_name":"Imaging phantom","score":0.6333768367767334},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.44538724422454834},{"id":"https://openalex.org/keywords/detector","display_name":"Detector","score":0.444699227809906},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4321284592151642},{"id":"https://openalex.org/keywords/notation","display_name":"Notation","score":0.43010902404785156},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.35295242071151733},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.27496659755706787},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.2628435492515564},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.19587993621826172},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.14608928561210632},{"id":"https://openalex.org/keywords/arithmetic","display_name":"Arithmetic","score":0.13371217250823975}],"concepts":[{"id":"https://openalex.org/C104293457","wikidata":"https://www.wikidata.org/wiki/Q28324852","display_name":"Imaging phantom","level":2,"score":0.6333768367767334},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.44538724422454834},{"id":"https://openalex.org/C94915269","wikidata":"https://www.wikidata.org/wiki/Q1834857","display_name":"Detector","level":2,"score":0.444699227809906},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4321284592151642},{"id":"https://openalex.org/C45357846","wikidata":"https://www.wikidata.org/wiki/Q2001982","display_name":"Notation","level":2,"score":0.43010902404785156},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.35295242071151733},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.27496659755706787},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2628435492515564},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.19587993621826172},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.14608928561210632},{"id":"https://openalex.org/C94375191","wikidata":"https://www.wikidata.org/wiki/Q11205","display_name":"Arithmetic","level":1,"score":0.13371217250823975},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/tim.2021.3066469","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tim.2021.3066469","pdf_url":null,"source":{"id":"https://openalex.org/S10892749","display_name":"IEEE Transactions on Instrumentation and Measurement","issn_l":"0018-9456","issn":["0018-9456","1557-9662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Instrumentation and Measurement","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W1540238411","https://openalex.org/W1919672897","https://openalex.org/W1948714585","https://openalex.org/W1965264388","https://openalex.org/W1981300574","https://openalex.org/W1989260609","https://openalex.org/W2016096865","https://openalex.org/W2033969122","https://openalex.org/W2051124281","https://openalex.org/W2058875695","https://openalex.org/W2063461906","https://openalex.org/W2063467100","https://openalex.org/W2065270937","https://openalex.org/W2070023462","https://openalex.org/W2085307945","https://openalex.org/W2087650854","https://openalex.org/W2093497547","https://openalex.org/W2106991982","https://openalex.org/W2111338181","https://openalex.org/W2112299151","https://openalex.org/W2126730443","https://openalex.org/W2130698183","https://openalex.org/W2132458261","https://openalex.org/W2132672139","https://openalex.org/W2135048288","https://openalex.org/W2148024230","https://openalex.org/W2150476025","https://openalex.org/W2154020433","https://openalex.org/W2163340196","https://openalex.org/W2166504108","https://openalex.org/W2254857825","https://openalex.org/W2322330265","https://openalex.org/W2340776089","https://openalex.org/W2343603483","https://openalex.org/W2430769700","https://openalex.org/W2464552791","https://openalex.org/W2528751697","https://openalex.org/W2532433594","https://openalex.org/W2548487117","https://openalex.org/W2570759363","https://openalex.org/W2578090560","https://openalex.org/W2611626092","https://openalex.org/W2772933431","https://openalex.org/W2792697330","https://openalex.org/W2793415794","https://openalex.org/W2797713293","https://openalex.org/W2889761000","https://openalex.org/W2902209227","https://openalex.org/W2939838557","https://openalex.org/W2954184802","https://openalex.org/W2978474546","https://openalex.org/W2986307104","https://openalex.org/W3000079306","https://openalex.org/W3009305891","https://openalex.org/W3019035599","https://openalex.org/W4248162713","https://openalex.org/W4385363761","https://openalex.org/W6678630771","https://openalex.org/W6929845168"],"related_works":["https://openalex.org/W2504004674","https://openalex.org/W2417440389","https://openalex.org/W4385556839","https://openalex.org/W4378746257","https://openalex.org/W2051487156","https://openalex.org/W2734382758","https://openalex.org/W2073681303","https://openalex.org/W2024638892","https://openalex.org/W2498744856","https://openalex.org/W763418848"],"abstract_inverted_index":{"Cerebral":[0],"tissue":[1,13,46],"oximetry":[2],"(CTO)":[3],"based":[4],"on":[5,12],"near-infrared":[6],"spectroscopy":[7],"provides":[8],"clinically":[9],"relevant":[10],"information":[11],"perfusion":[14],"and":[15,23,34,39,41,75,83,100,105,111,136,159,181,193,211,232,242,270],"has":[16],"been":[17],"used":[18],"specifically":[19],"in":[20,31,45,115,154,162],"infant":[21],"monitoring":[22],"during":[24],"cardiac":[25],"surgeries.":[26],"With":[27],"different":[28,60],"sensor":[29],"designs":[30],"the":[32,78,87,116,149,251],"selection":[33],"configuration":[35],"of":[36,89,118,151,207,250,265],"light":[37],"sources":[38],"detectors":[40],"implemented":[42,97],"analysis":[43,246],"algorithms":[44],"oxygen":[47,144],"saturation":[48,145],"(StO":[49],"<sub":[50],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[51,172,186,195,216],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">2</sub>":[52],")":[53,202],"extraction,":[54],"substantial":[55],"differences":[56],"were":[57,125,167,254],"observed":[58],"between":[59],"commercially":[61,120],"available":[62,121],"CTO":[63,90,122,129,155,164,252],"device":[64,91,130,139,156,165],"measurements.":[65],"Tissue":[66],"models":[67],"(phantoms)":[68],"mimicking":[69],"a":[70,137,263],"human":[71],"head":[72],"both":[73],"optically":[74],"anatomically":[76],"provide":[77],"controllable,":[79],"safe,":[80],"universally":[81],"agreeable,":[82],"reproducible":[84],"environment":[85],"for":[86,127],"evaluation":[88,117],"performances.":[92],"In":[93,238],"this":[94],"article,":[95],"we":[96],"our":[98,152],"realistic":[99],"dynamic":[101],"multilayer":[102],"mixed":[103],"solid":[104],"liquid":[106],"phantom":[107],"design":[108],"with":[109,258],"controlled":[110],"repeatable":[112],"test":[113],"procedures":[114],"multiple":[119],"devices.":[123],"Performances":[124],"evaluated":[126],"each":[128,134],"within":[131,255],"themselves,":[132],"across":[133],"other":[135],"reference":[138],"simultaneously":[140],"under":[141],"continuously":[142],"changing":[143],"conditions.":[146],"Results":[147],"indicated":[148],"feasibility":[150],"phantoms":[153],"performance":[157],"testing":[158],"suggested":[160],"that":[161,248],"general,":[163],"measurements":[166],"very":[168],"precise":[169],"(":[170,184,214],"<inline-formula":[171,185,194,215],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">":[173,187,196,217],"<tex-math":[174,188,197,218],"notation=\"LaTeX\">$S_{\\mathrm":[175],"{res}}":[176],"&lt;":[177,199,222],"1.48$":[178],"</tex-math></inline-formula>":[179,192,201,224],"%)":[180],"highly":[182],"correlated":[183],"notation=\"LaTeX\">$R^{2}":[189],"&gt;":[190],"0.89$":[191],"notation=\"LaTeX\">$p":[198],"0.0001$":[200],"but":[203],"had":[204],"varying":[205],"levels":[206],"accuracy,":[208],"sensitivity,":[209],"static,":[210],"proportional":[212],"bias":[213,234],"notation=\"LaTeX\">$15.4{\\%}&lt;":[219],"A_{\\mathrm":[220],"{rms}}":[221],"21.1$":[223],"%,":[225],"0.31":[226],"<":[227],"sensitivity":[228],"(regression":[229,235],"slope)":[230],"<0.43,":[231],"35.94<":[233],"intercept)":[236],"<49.74).":[237],"addition,":[239],"gauge":[240],"repeatability":[241],"reproducibility":[243],"(Gauge":[244],"R&R)":[245],"provided":[247],"most":[249],"devices":[253],"acceptable":[256],"ranges":[257],"precision-to-tolerance":[259],"(P/T)":[260],"ratio":[261],"<10%,":[262],"number":[264],"distinct":[266],"categories":[267],"(NDC)":[268],">5,":[269],"intraclass":[271],"correlation":[272],"coefficient":[273],"(ICC)":[274],">80%.":[275]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
