{"id":"https://openalex.org/W3094232608","doi":"https://doi.org/10.1109/tim.2020.3033057","title":"Automatic Repair of 3-D Neuron Reconstruction Based on Topological Feature Points and an MOST-Based Repairer","display_name":"Automatic Repair of 3-D Neuron Reconstruction Based on Topological Feature Points and an MOST-Based Repairer","publication_year":2020,"publication_date":"2020-10-22","ids":{"openalex":"https://openalex.org/W3094232608","doi":"https://doi.org/10.1109/tim.2020.3033057","mag":"3094232608"},"language":"en","primary_location":{"id":"doi:10.1109/tim.2020.3033057","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tim.2020.3033057","pdf_url":null,"source":{"id":"https://openalex.org/S10892749","display_name":"IEEE Transactions on Instrumentation and Measurement","issn_l":"0018-9456","issn":["0018-9456","1557-9662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Instrumentation and Measurement","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070673707","display_name":"Fuhao Yu","orcid":"https://orcid.org/0000-0002-6861-0003"},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]},{"id":"https://openalex.org/I4210144102","display_name":"Wuhu Hit Robot Technology Research Institute","ror":"https://ror.org/049w4dp92","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210144102"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fuhao Yu","raw_affiliation_strings":["College of Electrical and Information Engineering, Hunan University, Changsha, China","National Engineering Laboratory for Robot Visual Perception and Control Technology, Changsha, China"],"raw_orcid":"https://orcid.org/0000-0003-4713-4789","affiliations":[{"raw_affiliation_string":"College of Electrical and Information Engineering, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"National Engineering Laboratory for Robot Visual Perception and Control Technology, Changsha, China","institution_ids":["https://openalex.org/I4210144102"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100343854","display_name":"Min Liu","orcid":"https://orcid.org/0000-0001-6406-4896"},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]},{"id":"https://openalex.org/I4210144102","display_name":"Wuhu Hit Robot Technology Research Institute","ror":"https://ror.org/049w4dp92","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210144102"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Liu","raw_affiliation_strings":["College of Electrical and Information Engineering, Hunan University, Changsha, China","National Engineering Laboratory for Robot Visual Perception and Control Technology, Changsha, China"],"raw_orcid":"https://orcid.org/0000-0001-6406-4896","affiliations":[{"raw_affiliation_string":"College of Electrical and Information Engineering, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"National Engineering Laboratory for Robot Visual Perception and Control Technology, Changsha, China","institution_ids":["https://openalex.org/I4210144102"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011466255","display_name":"Weixun Chen","orcid":"https://orcid.org/0000-0002-1583-5807"},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]},{"id":"https://openalex.org/I4210144102","display_name":"Wuhu Hit Robot Technology Research Institute","ror":"https://ror.org/049w4dp92","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210144102"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weixun Chen","raw_affiliation_strings":["College of Electrical and Information Engineering, Hunan University, Changsha, China","National Engineering Laboratory for Robot Visual Perception and Control Technology, Changsha, China"],"raw_orcid":"https://orcid.org/0000-0002-1583-5807","affiliations":[{"raw_affiliation_string":"College of Electrical and Information Engineering, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"National Engineering Laboratory for Robot Visual Perception and Control Technology, Changsha, China","institution_ids":["https://openalex.org/I4210144102"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100682305","display_name":"He Wen","orcid":"https://orcid.org/0000-0001-8024-1899"},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]},{"id":"https://openalex.org/I4210144102","display_name":"Wuhu Hit Robot Technology Research Institute","ror":"https://ror.org/049w4dp92","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210144102"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"He Wen","raw_affiliation_strings":["College of Electrical and Information Engineering, Hunan University, Changsha, China","National Engineering Laboratory for Robot Visual Perception and Control Technology, Changsha, China"],"raw_orcid":"https://orcid.org/0000-0001-8024-1899","affiliations":[{"raw_affiliation_string":"College of Electrical and Information Engineering, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"National Engineering Laboratory for Robot Visual Perception and Control Technology, Changsha, China","institution_ids":["https://openalex.org/I4210144102"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025640070","display_name":"Yaonan Wang","orcid":"https://orcid.org/0000-0002-0519-6458"},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]},{"id":"https://openalex.org/I4210144102","display_name":"Wuhu Hit Robot Technology Research Institute","ror":"https://ror.org/049w4dp92","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210144102"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaonan Wang","raw_affiliation_strings":["College of Electrical and Information Engineering, Hunan University, Changsha, China","National Engineering Laboratory for Robot Visual Perception and Control Technology, Changsha, China"],"raw_orcid":"https://orcid.org/0000-0002-0519-6458","affiliations":[{"raw_affiliation_string":"College of Electrical and Information Engineering, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"National Engineering Laboratory for Robot Visual Perception and Control Technology, Changsha, China","institution_ids":["https://openalex.org/I4210144102"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059443966","display_name":"Tieyong Zeng","orcid":"https://orcid.org/0000-0002-0688-202X"},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Tieyong Zeng","raw_affiliation_strings":["The Chinese University of Hong Kong, Hong Kong"],"raw_orcid":"https://orcid.org/0000-0002-0688-202X","affiliations":[{"raw_affiliation_string":"The Chinese University of Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I177725633"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1297,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.84106357,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"70","issue":null,"first_page":"1","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9925000071525574,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.6556222438812256},{"id":"https://openalex.org/keywords/tracing","display_name":"Tracing","score":0.6549479961395264},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5969215035438538},{"id":"https://openalex.org/keywords/point","display_name":"Point (geometry)","score":0.5475415587425232},{"id":"https://openalex.org/keywords/ray-tracing","display_name":"Ray tracing (physics)","score":0.531618058681488},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5315154790878296},{"id":"https://openalex.org/keywords/feature-vector","display_name":"Feature vector","score":0.49288201332092285},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.4549540877342224},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.45329588651657104},{"id":"https://openalex.org/keywords/iterative-reconstruction","display_name":"Iterative reconstruction","score":0.4516840875148773},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.4381885528564453},{"id":"https://openalex.org/keywords/topology","display_name":"Topology (electrical circuits)","score":0.43786975741386414},{"id":"https://openalex.org/keywords/feature-extraction","display_name":"Feature extraction","score":0.4288303554058075},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.42637431621551514},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2701886296272278},{"id":"https://openalex.org/keywords/geometry","display_name":"Geometry","score":0.17278042435646057},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.11573615670204163},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.10384520888328552}],"concepts":[{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.6556222438812256},{"id":"https://openalex.org/C138673069","wikidata":"https://www.wikidata.org/wiki/Q322229","display_name":"Tracing","level":2,"score":0.6549479961395264},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5969215035438538},{"id":"https://openalex.org/C28719098","wikidata":"https://www.wikidata.org/wiki/Q44946","display_name":"Point (geometry)","level":2,"score":0.5475415587425232},{"id":"https://openalex.org/C121483023","wikidata":"https://www.wikidata.org/wiki/Q7298343","display_name":"Ray tracing (physics)","level":2,"score":0.531618058681488},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5315154790878296},{"id":"https://openalex.org/C83665646","wikidata":"https://www.wikidata.org/wiki/Q42139305","display_name":"Feature vector","level":2,"score":0.49288201332092285},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4549540877342224},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.45329588651657104},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.4516840875148773},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.4381885528564453},{"id":"https://openalex.org/C184720557","wikidata":"https://www.wikidata.org/wiki/Q7825049","display_name":"Topology (electrical circuits)","level":2,"score":0.43786975741386414},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.4288303554058075},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.42637431621551514},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2701886296272278},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.17278042435646057},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.11573615670204163},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.10384520888328552},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/tim.2020.3033057","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tim.2020.3033057","pdf_url":null,"source":{"id":"https://openalex.org/S10892749","display_name":"IEEE Transactions on Instrumentation and Measurement","issn_l":"0018-9456","issn":["0018-9456","1557-9662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Instrumentation and Measurement","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1259047040","display_name":null,"funder_award_id":"62073126","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3261378140","display_name":null,"funder_award_id":"2020JJ2008","funder_id":"https://openalex.org/F4320322843","funder_display_name":"Natural Science Foundation of\u00a0Hunan Province"},{"id":"https://openalex.org/G8810697831","display_name":"\u663e\u5fae\u56fe\u50cf\u6808\u4e2d\u8702\u7a9d\u72b6\u4e09\u7ef4\u7ec6\u80de\u7fa4\u7684\u8ffd\u8e2a\u53ca\u8c31\u7cfb\u6784\u5efa\u7814\u7a76","funder_award_id":"61771189","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322843","display_name":"Natural Science Foundation of\u00a0Hunan Province","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1427337929","https://openalex.org/W1508135620","https://openalex.org/W1534763723","https://openalex.org/W1559344731","https://openalex.org/W1971167883","https://openalex.org/W1973195069","https://openalex.org/W1989396876","https://openalex.org/W1992621211","https://openalex.org/W2010467836","https://openalex.org/W2011650974","https://openalex.org/W2018227909","https://openalex.org/W2028941104","https://openalex.org/W2036901575","https://openalex.org/W2074076835","https://openalex.org/W2075058103","https://openalex.org/W2086197761","https://openalex.org/W2092859932","https://openalex.org/W2108436498","https://openalex.org/W2119112562","https://openalex.org/W2124257654","https://openalex.org/W2153965609","https://openalex.org/W2156012604","https://openalex.org/W2157408013","https://openalex.org/W2202170526","https://openalex.org/W2209890352","https://openalex.org/W2404192493","https://openalex.org/W2560171554","https://openalex.org/W2587001086","https://openalex.org/W2618518139","https://openalex.org/W2677352953","https://openalex.org/W2889811300","https://openalex.org/W2910669864","https://openalex.org/W2912077506","https://openalex.org/W2917105198","https://openalex.org/W2921453818","https://openalex.org/W2951175011","https://openalex.org/W2952846208","https://openalex.org/W2966593583","https://openalex.org/W2971899185","https://openalex.org/W2979910668","https://openalex.org/W2982679883","https://openalex.org/W2997930275","https://openalex.org/W3001577996","https://openalex.org/W3011830677","https://openalex.org/W6632082525"],"related_works":["https://openalex.org/W2054109135","https://openalex.org/W2888673113","https://openalex.org/W2527954625","https://openalex.org/W2012819262","https://openalex.org/W2056065966","https://openalex.org/W2062641654","https://openalex.org/W2120224698","https://openalex.org/W2352602608","https://openalex.org/W2043557177","https://openalex.org/W2349351862"],"abstract_inverted_index":{"The":[0,95,119,141,172,190],"digital":[1],"reconstruction":[2,30],"of":[3,15,77,184],"neurons":[4],"is":[5,82,144,198],"essential":[6],"to":[7,12,42,146,168],"various":[8],"neuroscientific":[9],"studies.":[10],"Due":[11],"the":[13,22,49,74,78,98,102,109,124,129,133,138,148,153,159,165,169,178,185,195],"existence":[14],"gaps":[16],"and":[17,72,91,101,132],"ambiguities":[18],"in":[19,36,45],"neuron":[20,23,130],"images,":[21],"tracing":[24,161],"results":[25,174,192],"generated":[26],"by":[27,107,151],"most":[28],"automatic":[29,50],"algorithms":[31],"may":[32],"be":[33,43],"incomplete,":[34],"resulting":[35],"false":[37],"negatives":[38],"(FNs),":[39],"which":[40,81,163],"need":[41],"repaired":[44],"proof":[46],"editing.":[47],"However,":[48],"proof-editing":[51,67],"methods":[52],"for":[53,69,201],"repairing":[54,73],"FN":[55,75,99],"branches":[56,76],"have":[57],"rarely":[58],"been":[59],"explored.":[60],"In":[61],"this":[62],"study,":[63],"we":[64],"propose":[65],"a":[66,85,115],"algorithm":[68],"automatically":[70],"detecting":[71],"initial":[79,139,160],"reconstruction,":[80],"based":[83],"on":[84],"multiscale":[86,110],"upgraded":[87],"ray":[88],"(MUR)-shooting":[89],"model":[90],"an":[92],"MOST-based":[93,142],"repairer.":[94],"MUR":[96],"detects":[97],"branch":[100,104,155],"corresponding":[103],"direction":[105,156],"vector":[106,157],"analyzing":[108],"intensity":[111],"distribution":[112],"features":[113],"around":[114],"topological":[116,120],"feature":[117,121],"point.":[118],"points":[122,126],"contain":[123],"junction":[125],"detected":[127,154],"from":[128,137],"image":[131],"tip":[134],"nodes":[135,166],"extracted":[136],"reconstruction.":[140],"repairer":[143],"proposed":[145,179,196],"prevent":[147],"redundant":[149],"reconstructions":[150],"assigning":[152],"as":[158],"direction,":[162],"rejects":[164],"returning":[167],"traced":[170],"area.":[171],"experimental":[173,191],"demonstrate":[175],"clearly":[176],"that":[177,194],"method":[180,197],"can":[181],"reduce":[182],"20%":[183],"false-negative":[186],"rate":[187],"at":[188],"most.":[189],"confirm":[193],"extremely":[199],"helpful":[200],"generating":[202],"faithful":[203],"reconstructions.":[204]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":3}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}
