{"id":"https://openalex.org/W3007926858","doi":"https://doi.org/10.1109/tim.2020.2973913","title":"BrightNet: A Deep CNN for OLED-Based Point of Care Immunofluorescent Diagnostic Systems","display_name":"BrightNet: A Deep CNN for OLED-Based Point of Care Immunofluorescent Diagnostic Systems","publication_year":2020,"publication_date":"2020-02-18","ids":{"openalex":"https://openalex.org/W3007926858","doi":"https://doi.org/10.1109/tim.2020.2973913","mag":"3007926858"},"language":"en","primary_location":{"id":"doi:10.1109/tim.2020.2973913","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tim.2020.2973913","pdf_url":null,"source":{"id":"https://openalex.org/S10892749","display_name":"IEEE Transactions on Instrumentation and Measurement","issn_l":"0018-9456","issn":["0018-9456","1557-9662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Instrumentation and Measurement","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hdl.handle.net/11585/771945","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015743482","display_name":"Andrea Samor\u00e8","orcid":"https://orcid.org/0000-0001-9524-4443"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Samore","raw_affiliation_strings":["Department of Mathematics, University of Bologna, Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mathematics, University of Bologna, Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030025275","display_name":"Manuele Rusci","orcid":"https://orcid.org/0000-0001-7458-4019"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Manuele Rusci","raw_affiliation_strings":["Department of Electrical, Electronic and Information Engineering, University of Bologna, Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical, Electronic and Information Engineering, University of Bologna, Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020989016","display_name":"Damiana Lazzaro","orcid":"https://orcid.org/0000-0002-2029-9842"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Damiana Lazzaro","raw_affiliation_strings":["Department of Mathematics, University of Bologna, Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mathematics, University of Bologna, Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014261537","display_name":"Patrizia Melpignano","orcid":null},"institutions":[{"id":"https://openalex.org/I4210151289","display_name":"Elektro Ljubljana (Slovenia)","ror":"https://ror.org/03r9v0161","country_code":"SI","type":"company","lineage":["https://openalex.org/I4210151289"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Patrizia Melpignano","raw_affiliation_strings":["OR-EL d.o.o. Organska Elektronika, Kobarid, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"OR-EL d.o.o. Organska Elektronika, Kobarid, Slovenia","institution_ids":["https://openalex.org/I4210151289"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043408422","display_name":"Luca Benini","orcid":"https://orcid.org/0000-0001-8068-3806"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luca Benini","raw_affiliation_strings":["Department of Electrical, Electronic and Information Engineering, University of Bologna, Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical, Electronic and Information Engineering, University of Bologna, Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058921917","display_name":"Serena Morigi","orcid":"https://orcid.org/0000-0001-8334-8798"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Serena Morigi","raw_affiliation_strings":["Department of Mathematics, University of Bologna, Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mathematics, University of Bologna, Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5158,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.56514441,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"69","issue":"9","first_page":"6766","last_page":"6775"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.666429340839386},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.6278003454208374},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.597252607345581},{"id":"https://openalex.org/keywords/point-of-care","display_name":"Point of care","score":0.5210741758346558},{"id":"https://openalex.org/keywords/detector","display_name":"Detector","score":0.5026431083679199},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3933791220188141},{"id":"https://openalex.org/keywords/computer-hardware","display_name":"Computer hardware","score":0.35652345418930054},{"id":"https://openalex.org/keywords/embedded-system","display_name":"Embedded system","score":0.3303224742412567}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.666429340839386},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.6278003454208374},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.597252607345581},{"id":"https://openalex.org/C51915194","wikidata":"https://www.wikidata.org/wiki/Q17075487","display_name":"Point of care","level":2,"score":0.5210741758346558},{"id":"https://openalex.org/C94915269","wikidata":"https://www.wikidata.org/wiki/Q1834857","display_name":"Detector","level":2,"score":0.5026431083679199},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3933791220188141},{"id":"https://openalex.org/C9390403","wikidata":"https://www.wikidata.org/wiki/Q3966","display_name":"Computer hardware","level":1,"score":0.35652345418930054},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.3303224742412567},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/tim.2020.2973913","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tim.2020.2973913","pdf_url":null,"source":{"id":"https://openalex.org/S10892749","display_name":"IEEE Transactions on Instrumentation and Measurement","issn_l":"0018-9456","issn":["0018-9456","1557-9662"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Instrumentation and Measurement","raw_type":"journal-article"},{"id":"pmh:oai:cris.unibo.it:11585/768714","is_oa":false,"landing_page_url":"http://hdl.handle.net/11585/768714","pdf_url":null,"source":{"id":"https://openalex.org/S4306402579","display_name":"Archivio istituzionale della ricerca (Alma Mater Studiorum Universit\u00e0 di Bologna)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210117483","host_organization_name":"Istituto di Ematologia di Bologna","host_organization_lineage":["https://openalex.org/I4210117483"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:cris.unibo.it:11585/771945","is_oa":true,"landing_page_url":"https://hdl.handle.net/11585/771945","pdf_url":null,"source":{"id":"https://openalex.org/S4306402579","display_name":"Archivio istituzionale della ricerca (Alma Mater Studiorum Universit\u00e0 di Bologna)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210117483","host_organization_name":"Istituto di Ematologia di Bologna","host_organization_lineage":["https://openalex.org/I4210117483"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:cris.unibo.it:11585/771945","is_oa":true,"landing_page_url":"https://hdl.handle.net/11585/771945","pdf_url":null,"source":{"id":"https://openalex.org/S4306402579","display_name":"Archivio istituzionale della ricerca (Alma Mater Studiorum Universit\u00e0 di Bologna)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210117483","host_organization_name":"Istituto di Ematologia di Bologna","host_organization_lineage":["https://openalex.org/I4210117483"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/16","score":0.6700000166893005,"display_name":"Peace, Justice and strong institutions"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W639708223","https://openalex.org/W1522301498","https://openalex.org/W1533861849","https://openalex.org/W1901129140","https://openalex.org/W2043826743","https://openalex.org/W2046033161","https://openalex.org/W2076958395","https://openalex.org/W2079258367","https://openalex.org/W2093378116","https://openalex.org/W2108598243","https://openalex.org/W2121988986","https://openalex.org/W2137216039","https://openalex.org/W2193145675","https://openalex.org/W2346062110","https://openalex.org/W2612445135","https://openalex.org/W2766652319","https://openalex.org/W2768879211","https://openalex.org/W2794183899","https://openalex.org/W2812373594","https://openalex.org/W2895432151","https://openalex.org/W2899280016","https://openalex.org/W2899771611","https://openalex.org/W2963037989","https://openalex.org/W2963163009","https://openalex.org/W2963364380","https://openalex.org/W2964121744","https://openalex.org/W2964249569","https://openalex.org/W3106250896","https://openalex.org/W3110237708","https://openalex.org/W4297775537","https://openalex.org/W4313315460","https://openalex.org/W6631190155","https://openalex.org/W6631943919","https://openalex.org/W6737664043","https://openalex.org/W6745905613","https://openalex.org/W6755325935","https://openalex.org/W6756040250","https://openalex.org/W7023881829"],"related_works":["https://openalex.org/W4293226380","https://openalex.org/W2366906938","https://openalex.org/W2349391998","https://openalex.org/W4205655149","https://openalex.org/W2000775715","https://openalex.org/W2795393339","https://openalex.org/W2074467390","https://openalex.org/W4254303342","https://openalex.org/W4390618967","https://openalex.org/W2626393719"],"abstract_inverted_index":{"An":[0],"automatic":[1],"tool,":[2],"targeting":[3],"low-cost,":[4],"low-power,":[5],"point-of-care":[6],"embedded":[7,34],"system,":[8],"is":[9,62,103,117,128],"proposed":[10,56],"for":[11,17,105,150,172],"fluorescence":[12],"diagnostic":[13,187],"imaging.":[14],"This":[15],"allows":[16],"a":[18,53,65,81,109,164,195],"quick":[19],"and":[20,87,127,153,210],"accurate":[21],"diagnosis":[22,174],"even":[23],"when":[24],"used":[25],"by":[26],"nonexpert":[27],"operators.":[28],"To":[29],"achieve":[30],"this":[31],"goal,":[32],"an":[33,40,122,137],"system":[35],"has":[36,146],"been":[37,147],"equipped":[38],"with":[39,203],"end-to-end":[41],"deep-learning":[42],"algorithm":[43],"that":[44,199],"does":[45],"not":[46],"require":[47],"manual":[48],"parameter":[49],"tuning":[50],"to":[51,71,96,130],"perform":[52],"diagnosis.":[54,90,212],"The":[55,113],"deep":[57],"convolutional":[58],"model,":[59],"named":[60],"BrightNet,":[61],"based":[63],"on":[64,121,136,184],"single-shot":[66],"detector":[67],"neural":[68],"network,":[69],"modified":[70],"estimate":[72],"the":[73,76,89,98,106,151,160,173,185],"brightness":[74],"of":[75,155,159,166,175,207],"detected":[77],"fluorescent":[78],"spots":[79],"in":[80,163,179],"low-density":[82],"protein":[83],"or":[84],"DNA":[85],"microarray":[86],"finalize":[88],"Several":[91],"optimization":[92],"steps":[93],"are":[94],"presented":[95],"compress":[97],"inference":[99,115],"model":[100],"size,":[101],"which":[102],"required":[104],"deployment":[107],"into":[108],"portable":[110],"resource-constrained":[111],"device.":[112],"resulting":[114],"time":[116],"about":[118],"66":[119],"[ms]":[120],"i7":[123],"3770K":[124],"desktop":[125],"CPU":[126],"estimated":[129],"be":[131],"lower":[132],"than":[133,194],"5":[134],"[s]":[135],"ARM-Cortex":[138],"M7":[139],"considering":[140],"1.1":[141],"\u00d7":[142],"109multiply-accumulate":[143],"operations.":[144],"BrightNet":[145,189],"successfully":[148],"validated":[149],"detection":[152],"discrimination":[154],"four":[156],"different":[157],"serotypes":[158],"dengue":[161],"virus":[162,178],"set":[165],"human":[167],"samples":[168],"as":[169,171],"well":[170],"West":[176],"Nile":[177],"horse":[180],"sera.":[181],"When":[182],"evaluated":[183],"considered":[186],"tasks,":[188],"provides":[190],"better":[191],"average":[192],"accuracy":[193],"state-of-the-art":[196],"variational":[197],"approach":[198],"requires":[200],"operator":[201],"intervention,":[202],"significant":[204],"additional":[205],"advantages":[206],"complete":[208],"automation":[209],"quicker":[211]},"counts_by_year":[{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-07-29T09:40:50.615796","created_date":"2020-03-06T00:00:00"}