{"id":"https://openalex.org/W2149159583","doi":"https://doi.org/10.1109/tfuzz.2010.2070842","title":"Robust Optimal Reference-Tracking Design Method for Stochastic Synthetic Biology Systems: T\u2013S Fuzzy Approach","display_name":"Robust Optimal Reference-Tracking Design Method for Stochastic Synthetic Biology Systems: T\u2013S Fuzzy Approach","publication_year":2010,"publication_date":"2010-09-01","ids":{"openalex":"https://openalex.org/W2149159583","doi":"https://doi.org/10.1109/tfuzz.2010.2070842","mag":"2149159583"},"language":"en","primary_location":{"id":"doi:10.1109/tfuzz.2010.2070842","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tfuzz.2010.2070842","pdf_url":null,"source":{"id":"https://openalex.org/S134177497","display_name":"IEEE Transactions on Fuzzy Systems","issn_l":"1063-6706","issn":["1063-6706","1941-0034"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Fuzzy Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038219293","display_name":"Bor\u2010Sen Chen","orcid":"https://orcid.org/0000-0003-1644-6106"},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Bor-Sen Chen","raw_affiliation_strings":["Laboratory of Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu, Taiwan"],"affiliations":[{"raw_affiliation_string":"Laboratory of Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004066253","display_name":"Chih\u2010Hung Wu","orcid":"https://orcid.org/0000-0003-3804-0852"},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chih-Hung Wu","raw_affiliation_strings":["Laboratory of Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu, Taiwan"],"affiliations":[{"raw_affiliation_string":"Laboratory of Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I25846049"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5038219293"],"corresponding_institution_ids":["https://openalex.org/I25846049"],"apc_list":null,"apc_paid":null,"fwci":4.2295,"has_fulltext":false,"cited_by_count":77,"citation_normalized_percentile":{"value":0.95014459,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"18","issue":"6","first_page":"1144","last_page":"1159"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9732999801635742,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nonlinear-system","display_name":"Nonlinear system","score":0.6332738399505615},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5789162516593933},{"id":"https://openalex.org/keywords/synthetic-biology","display_name":"Synthetic biology","score":0.5460157990455627},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.5231174826622009},{"id":"https://openalex.org/keywords/control-theory","display_name":"Control theory (sociology)","score":0.5205134749412537},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.46789777278900146},{"id":"https://openalex.org/keywords/robust-control","display_name":"Robust control","score":0.4461984634399414},{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.43739423155784607},{"id":"https://openalex.org/keywords/stochastic-process","display_name":"Stochastic process","score":0.42965418100357056},{"id":"https://openalex.org/keywords/convex-optimization","display_name":"Convex optimization","score":0.4122537672519684},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2935577630996704},{"id":"https://openalex.org/keywords/regular-polygon","display_name":"Regular polygon","score":0.19608867168426514},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.15292054414749146},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.10066935420036316},{"id":"https://openalex.org/keywords/control","display_name":"Control (management)","score":0.08950874209403992}],"concepts":[{"id":"https://openalex.org/C158622935","wikidata":"https://www.wikidata.org/wiki/Q660848","display_name":"Nonlinear system","level":2,"score":0.6332738399505615},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5789162516593933},{"id":"https://openalex.org/C191908910","wikidata":"https://www.wikidata.org/wiki/Q862838","display_name":"Synthetic biology","level":2,"score":0.5460157990455627},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.5231174826622009},{"id":"https://openalex.org/C47446073","wikidata":"https://www.wikidata.org/wiki/Q5165890","display_name":"Control theory (sociology)","level":3,"score":0.5205134749412537},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.46789777278900146},{"id":"https://openalex.org/C31531917","wikidata":"https://www.wikidata.org/wiki/Q915157","display_name":"Robust control","level":3,"score":0.4461984634399414},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.43739423155784607},{"id":"https://openalex.org/C8272713","wikidata":"https://www.wikidata.org/wiki/Q176737","display_name":"Stochastic process","level":2,"score":0.42965418100357056},{"id":"https://openalex.org/C157972887","wikidata":"https://www.wikidata.org/wiki/Q463359","display_name":"Convex optimization","level":3,"score":0.4122537672519684},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2935577630996704},{"id":"https://openalex.org/C112680207","wikidata":"https://www.wikidata.org/wiki/Q714886","display_name":"Regular polygon","level":2,"score":0.19608867168426514},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.15292054414749146},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.10066935420036316},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.08950874209403992},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/tfuzz.2010.2070842","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tfuzz.2010.2070842","pdf_url":null,"source":{"id":"https://openalex.org/S134177497","display_name":"IEEE Transactions on Fuzzy Systems","issn_l":"1063-6706","issn":["1063-6706","1941-0034"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Fuzzy Systems","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W562026345","https://openalex.org/W1501946873","https://openalex.org/W1515213997","https://openalex.org/W1532932064","https://openalex.org/W1547106545","https://openalex.org/W1599969036","https://openalex.org/W1602992657","https://openalex.org/W1645305843","https://openalex.org/W1699920107","https://openalex.org/W1972826618","https://openalex.org/W1987184800","https://openalex.org/W1988898793","https://openalex.org/W2006188622","https://openalex.org/W2008880969","https://openalex.org/W2017496074","https://openalex.org/W2017862866","https://openalex.org/W2029682651","https://openalex.org/W2045095831","https://openalex.org/W2055093780","https://openalex.org/W2058221907","https://openalex.org/W2061974849","https://openalex.org/W2065868883","https://openalex.org/W2079325629","https://openalex.org/W2089022150","https://openalex.org/W2091731123","https://openalex.org/W2096127979","https://openalex.org/W2096438606","https://openalex.org/W2102872235","https://openalex.org/W2103931515","https://openalex.org/W2107461460","https://openalex.org/W2110071847","https://openalex.org/W2110553053","https://openalex.org/W2114020393","https://openalex.org/W2116322295","https://openalex.org/W2121354282","https://openalex.org/W2130565092","https://openalex.org/W2131465376","https://openalex.org/W2137510998","https://openalex.org/W2142581072","https://openalex.org/W2143142281","https://openalex.org/W2144588155","https://openalex.org/W2148131504","https://openalex.org/W2150989626","https://openalex.org/W2158601988","https://openalex.org/W2161487768","https://openalex.org/W2185337155","https://openalex.org/W2491188924","https://openalex.org/W2528271650","https://openalex.org/W2914825457","https://openalex.org/W3210839039","https://openalex.org/W4213345774","https://openalex.org/W4246586762","https://openalex.org/W4302033101"],"related_works":["https://openalex.org/W2501936778","https://openalex.org/W2072526354","https://openalex.org/W3141738981","https://openalex.org/W2099102792","https://openalex.org/W4254255930","https://openalex.org/W1987184800","https://openalex.org/W4296154543","https://openalex.org/W4312717466","https://openalex.org/W2475404136","https://openalex.org/W1542318010"],"abstract_inverted_index":{"At":[0],"present,":[1],"the":[2,5,41,66,70,80,95,112,137,141,161,165,175,184,191,205,229,253],"development":[3],"in":[4,74,103,128],"nascent":[6],"field":[7],"of":[8,35,99,123,130,147,164,258],"synthetic":[9,75,100,114,149,172,224,259],"gene":[10,18,50,101,115,150,173,225,260],"networks":[11,19,102,151,226],"is":[12,53,69,152,180,221,244],"still":[13,153],"difficult.":[14],"Most":[15],"newly":[16],"created":[17],"are":[20,92,108],"nonfunctioning":[21],"due":[22],"to":[23,45,54,110,155,159,182,227,233,251],"intrinsic":[24,61,81,132],"parameter":[25,82],"fluctuations,":[26,83],"uncertain":[27,84],"interactions":[28,85],"with":[29,86],"unknown":[30,87],"molecules":[31,88],"and":[32,37,62,89,133],"external":[33],"disturbances":[34,64,135],"intra":[36],"extracellular":[38],"environments":[39],"on":[40,65,136],"host":[42,67,138],"cell.":[43,139],"How":[44],"design":[46,106,145,162,170,188,195,199,219,231,242,256],"a":[47,124,217],"completely":[48],"new":[49],"network,":[51,116],"that":[52],"track":[55],"some":[56],"desired":[57,125],"behaviors":[58],"under":[59,197],"these":[60,131],"extrinsic":[63,134],"cell,":[68],"most":[71],"important":[72],"topic":[73],"biology.":[76],"In":[77,157],"this":[78],"study,":[79],"environmental":[90],"disturbances,":[91],"modeled":[93],"into":[94],"nonlinear":[96,148,168,185],"stochastic":[97,113,186,254],"systems":[98],"vivo.":[104],"Four":[105],"specifications":[107,200,232],"introduced":[109,181],"guarantee":[111],"which":[117],"can":[118,201],"achieve":[119,234],"robust":[120,142,166,192,235],"optimal":[121,143,167,193,236],"tracking":[122],"reference":[126,237],"model":[127],"spite":[129],"However,":[140],"reference-tracking":[144,194],"problem":[146,196],"hard":[154],"solve.":[156],"order":[158],"simplify":[160],"procedure":[163,220],"stochastic-tracking":[169],"for":[171,223],"networks,":[174],"Takagi-Sugeno":[176],"(T-S)":[177],"fuzzy":[178],"method":[179,211,243,257],"solve":[183],"minimum-error-tracking":[187],"problem.":[189],"Hence,":[190],"four":[198,230],"be":[202],"solved":[203],"by":[204],"linear":[206],"matrix":[207],"inequality":[208],"(LMI)-constrained":[209],"optimization":[210,214],"using":[212],"convex":[213],"techniques.":[215],"Further,":[216],"simple":[218],"developed":[222],"meet":[228],"tracking.":[238],"Finally,":[239],"an":[240,248],"eigenvalue-shifted":[241],"also":[245],"proposed":[246],"as":[247],"expedient":[249],"scheme":[250],"improve":[252],"optimal-tracking":[255],"oscillators.":[261]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":9}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}