{"id":"https://openalex.org/W2884449147","doi":"https://doi.org/10.1109/tcomm.2018.2859308","title":"Parity-Check Coding Based on Genetic Circuits for Engineered Molecular Communication Between Biological Cells","display_name":"Parity-Check Coding Based on Genetic Circuits for Engineered Molecular Communication Between Biological Cells","publication_year":2018,"publication_date":"2018-07-24","ids":{"openalex":"https://openalex.org/W2884449147","doi":"https://doi.org/10.1109/tcomm.2018.2859308","mag":"2884449147"},"language":"en","primary_location":{"id":"doi:10.1109/tcomm.2018.2859308","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcomm.2018.2859308","pdf_url":null,"source":{"id":"https://openalex.org/S196647941","display_name":"IEEE Transactions on Communications","issn_l":"0090-6778","issn":["0090-6778","1558-0857"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310316002","host_organization_name":"IEEE Communications Society","host_organization_lineage":["https://openalex.org/P4310316002","https://openalex.org/P4310319808"],"host_organization_lineage_names":["IEEE Communications Society","Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Communications","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11311/1085578","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050547654","display_name":"Alessio Marcone","orcid":null},"institutions":[{"id":"https://openalex.org/I93860229","display_name":"Politecnico di Milano","ror":"https://ror.org/01nffqt88","country_code":"IT","type":"education","lineage":["https://openalex.org/I93860229"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Alessio Marcone","raw_affiliation_strings":["Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy","institution_ids":["https://openalex.org/I93860229"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039872937","display_name":"Massimiliano Pierobon","orcid":"https://orcid.org/0000-0003-1074-6925"},"institutions":[{"id":"https://openalex.org/I114395901","display_name":"University of Nebraska\u2013Lincoln","ror":"https://ror.org/043mer456","country_code":"US","type":"education","lineage":["https://openalex.org/I114395901"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Massimiliano Pierobon","raw_affiliation_strings":["Department of Computer Science and Engineering, University of Nebraska\u2013Lincoln, Lincoln, NE, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, University of Nebraska\u2013Lincoln, Lincoln, NE, USA","institution_ids":["https://openalex.org/I114395901"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026125746","display_name":"Maurizio Magarini","orcid":"https://orcid.org/0000-0001-9288-0452"},"institutions":[{"id":"https://openalex.org/I93860229","display_name":"Politecnico di Milano","ror":"https://ror.org/01nffqt88","country_code":"IT","type":"education","lineage":["https://openalex.org/I93860229"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maurizio Magarini","raw_affiliation_strings":["Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy","institution_ids":["https://openalex.org/I93860229"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5050547654"],"corresponding_institution_ids":["https://openalex.org/I93860229"],"apc_list":null,"apc_paid":null,"fwci":3.3271,"has_fulltext":true,"cited_by_count":44,"citation_normalized_percentile":{"value":0.9264811,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"66","issue":"12","first_page":"6221","last_page":"6236"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13052","display_name":"Molecular Communication and Nanonetworks","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13052","display_name":"Molecular Communication and Nanonetworks","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9919000267982483,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.984499990940094,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/molecular-communication","display_name":"Molecular communication","score":0.8645312786102295},{"id":"https://openalex.org/keywords/synthetic-biology","display_name":"Synthetic biology","score":0.7622616291046143},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6350672841072083},{"id":"https://openalex.org/keywords/electronic-circuit","display_name":"Electronic circuit","score":0.5799316167831421},{"id":"https://openalex.org/keywords/encoder","display_name":"Encoder","score":0.5366384983062744},{"id":"https://openalex.org/keywords/digital-electronics","display_name":"Digital electronics","score":0.4581855833530426},{"id":"https://openalex.org/keywords/electronic-engineering","display_name":"Electronic engineering","score":0.4491522014141083},{"id":"https://openalex.org/keywords/decoding-methods","display_name":"Decoding methods","score":0.4381554424762726},{"id":"https://openalex.org/keywords/encoding","display_name":"Encoding (memory)","score":0.41594821214675903},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.3459450602531433},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.21168005466461182},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.19574299454689026},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.16416937112808228},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.16024908423423767},{"id":"https://openalex.org/keywords/telecommunications","display_name":"Telecommunications","score":0.15880754590034485},{"id":"https://openalex.org/keywords/electrical-engineering","display_name":"Electrical engineering","score":0.1559896171092987},{"id":"https://openalex.org/keywords/channel","display_name":"Channel (broadcasting)","score":0.13339194655418396},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.12780681252479553}],"concepts":[{"id":"https://openalex.org/C2779767902","wikidata":"https://www.wikidata.org/wiki/Q17037278","display_name":"Molecular communication","level":4,"score":0.8645312786102295},{"id":"https://openalex.org/C191908910","wikidata":"https://www.wikidata.org/wiki/Q862838","display_name":"Synthetic biology","level":2,"score":0.7622616291046143},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6350672841072083},{"id":"https://openalex.org/C134146338","wikidata":"https://www.wikidata.org/wiki/Q1815901","display_name":"Electronic circuit","level":2,"score":0.5799316167831421},{"id":"https://openalex.org/C118505674","wikidata":"https://www.wikidata.org/wiki/Q42586063","display_name":"Encoder","level":2,"score":0.5366384983062744},{"id":"https://openalex.org/C81843906","wikidata":"https://www.wikidata.org/wiki/Q173156","display_name":"Digital electronics","level":3,"score":0.4581855833530426},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.4491522014141083},{"id":"https://openalex.org/C57273362","wikidata":"https://www.wikidata.org/wiki/Q576722","display_name":"Decoding methods","level":2,"score":0.4381554424762726},{"id":"https://openalex.org/C125411270","wikidata":"https://www.wikidata.org/wiki/Q18653","display_name":"Encoding (memory)","level":2,"score":0.41594821214675903},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.3459450602531433},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.21168005466461182},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.19574299454689026},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.16416937112808228},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.16024908423423767},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.15880754590034485},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.1559896171092987},{"id":"https://openalex.org/C127162648","wikidata":"https://www.wikidata.org/wiki/Q16858953","display_name":"Channel (broadcasting)","level":2,"score":0.13339194655418396},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12780681252479553},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C47798520","wikidata":"https://www.wikidata.org/wiki/Q190157","display_name":"Transmitter","level":3,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/tcomm.2018.2859308","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcomm.2018.2859308","pdf_url":null,"source":{"id":"https://openalex.org/S196647941","display_name":"IEEE Transactions on Communications","issn_l":"0090-6778","issn":["0090-6778","1558-0857"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310316002","host_organization_name":"IEEE Communications Society","host_organization_lineage":["https://openalex.org/P4310316002","https://openalex.org/P4310319808"],"host_organization_lineage_names":["IEEE Communications Society","Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Communications","raw_type":"journal-article"},{"id":"pmh:oai:re.public.polimi.it:11311/1085578","is_oa":true,"landing_page_url":"http://hdl.handle.net/11311/1085578","pdf_url":"http://hdl.handle.net/11311/1085578","source":{"id":"https://openalex.org/S4306400312","display_name":"Virtual Community of Pathological Anatomy (University of Castilla La Mancha)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I79189158","host_organization_name":"University of Castilla-La Mancha","host_organization_lineage":["https://openalex.org/I79189158"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:re.public.polimi.it:11311/1085578","is_oa":true,"landing_page_url":"http://hdl.handle.net/11311/1085578","pdf_url":"http://hdl.handle.net/11311/1085578","source":{"id":"https://openalex.org/S4306400312","display_name":"Virtual Community of Pathological Anatomy (University of Castilla La Mancha)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I79189158","host_organization_name":"University of Castilla-La Mancha","host_organization_lineage":["https://openalex.org/I79189158"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1860884660","display_name":null,"funder_award_id":"CCF-1816969","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G2307325783","display_name":null,"funder_award_id":"CISE CCF-1816969","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G3605044243","display_name":"CIF: Small: WetComm:Foundations of Wet Communication Theory","funder_award_id":"1816969","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G5660979040","display_name":null,"funder_award_id":"CCF-1816969","funder_id":"https://openalex.org/F4320332169","funder_display_name":"Directorate for Computer and Information Science and Engineering"},{"id":"https://openalex.org/G848032724","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332169","display_name":"Directorate for Computer and Information Science and Engineering","ror":"https://ror.org/025kzpk63"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2884449147.pdf","grobid_xml":"https://content.openalex.org/works/W2884449147.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W35463602","https://openalex.org/W257897778","https://openalex.org/W655237379","https://openalex.org/W1530997919","https://openalex.org/W1584397582","https://openalex.org/W1599016019","https://openalex.org/W1599969036","https://openalex.org/W1651537430","https://openalex.org/W1977624796","https://openalex.org/W1981083886","https://openalex.org/W1983823597","https://openalex.org/W1984920148","https://openalex.org/W1990856168","https://openalex.org/W2023645154","https://openalex.org/W2026016792","https://openalex.org/W2027576577","https://openalex.org/W2032013720","https://openalex.org/W2042513636","https://openalex.org/W2050492893","https://openalex.org/W2059488492","https://openalex.org/W2065833295","https://openalex.org/W2079514822","https://openalex.org/W2090609904","https://openalex.org/W2093072521","https://openalex.org/W2112296120","https://openalex.org/W2116194016","https://openalex.org/W2119742312","https://openalex.org/W2125287028","https://openalex.org/W2130173145","https://openalex.org/W2139129605","https://openalex.org/W2143177102","https://openalex.org/W2148064314","https://openalex.org/W2149778176","https://openalex.org/W2151930053","https://openalex.org/W2168002711","https://openalex.org/W2168762395","https://openalex.org/W2169061810","https://openalex.org/W2171125625","https://openalex.org/W2185382521","https://openalex.org/W2244769090","https://openalex.org/W2317153111","https://openalex.org/W2486112781","https://openalex.org/W2509167823","https://openalex.org/W2511512977","https://openalex.org/W2513698684","https://openalex.org/W2545779952","https://openalex.org/W2742163087","https://openalex.org/W2761811715","https://openalex.org/W2778051563","https://openalex.org/W2965858921","https://openalex.org/W3098477036","https://openalex.org/W3100991707","https://openalex.org/W3195319736","https://openalex.org/W4233304250","https://openalex.org/W6635806747","https://openalex.org/W6799871304"],"related_works":["https://openalex.org/W2163496989","https://openalex.org/W2054910325","https://openalex.org/W3135645983","https://openalex.org/W3000508184","https://openalex.org/W2554633690","https://openalex.org/W4283822356","https://openalex.org/W1950940422","https://openalex.org/W2129146436","https://openalex.org/W2032507829","https://openalex.org/W2147282173"],"abstract_inverted_index":{"Synthetic":[0],"biology,":[1],"through":[2,163],"genetic":[3,86],"circuit":[4],"engineering":[5,77],"in":[6,117,159],"biological":[7,32,118],"cells,":[8],"is":[9,95,135],"paving":[10],"the":[11,14,31,34,39,63,67,83,110,122,129,142,147,151,160,183],"way":[12],"toward":[13],"realization":[15],"of":[16,38,66,69,85,112,124,131,146,167],"programmable":[17],"man-made":[18],"living":[19],"devices,":[20,47],"able":[21],"to":[22,78,88,181],"naturally":[23],"operate":[24],"within":[25],"normally":[26],"less":[27],"accessible":[28],"domains,":[29],"i.e.,":[30,54],"and":[33,42,51,104,165,169],"nanoscale.":[35],"The":[36],"control":[37],"information":[40,102,148],"processing":[41],"exchange":[43],"between":[44,92],"these":[45],"engineered-cell":[46],"based":[48],"on":[49],"molecules":[50],"biochemical":[52,161,170],"reactions,":[53,171],"molecular":[55],"communication":[56],"(MC),":[57],"will":[58],"be":[59],"enabling":[60],"technologies":[61],"for":[62,101,128],"emerging":[64],"paradigm":[65],"Internet":[68],"Bio-Nano":[70],"Things,":[71],"with":[72,137],"applications":[73],"ranging":[74],"from":[75,99,150],"tissue":[76],"bioremediation.":[79],"In":[80,120],"this":[81],"paper,":[82],"design":[84,123,185],"circuits":[87],"enable":[89],"MC":[90],"links":[91],"engineered":[93],"cells":[94],"proposed":[96,184],"by":[97,106,196],"stemming":[98],"techniques":[100],"coding":[103],"inspired":[105],"recent":[107],"studies":[108],"favoring":[109],"efficiency":[111],"analog":[113],"computation":[114],"over":[115],"digital":[116],"cells.":[119],"particular,":[121],"a":[125,138,187],"joint":[126],"encoder-modulator":[127],"transmission":[130],"binary-modulated":[132],"molecule":[133],"concentration":[134],"coupled":[136],"decoder":[139],"that":[140],"computes":[141],"a-posteriori":[143],"log-likelihood":[144],"ratio":[145],"bits":[149],"propagated":[152],"concentration.":[153],"These":[154],"functionalities":[155],"are":[156,179],"implemented":[157],"entirely":[158],"domain":[162],"activation":[164],"repression":[166],"genes,":[168],"rather":[172],"than":[173],"classical":[174],"electrical":[175],"circuits.":[176],"Biochemical":[177],"simulations":[178],"used":[180],"evaluate":[182],"against":[186],"theoretical":[188],"encoder/decoder":[189],"implementation":[190],"taking":[191],"into":[192],"account":[193],"impairments":[194],"introduced":[195],"diffusion":[197],"noise.":[198]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":15},{"year":2018,"cited_by_count":1}],"updated_date":"2026-03-18T14:38:29.013473","created_date":"2025-10-10T00:00:00"}