{"id":"https://openalex.org/W4414162130","doi":"https://doi.org/10.1109/tcbbio.2025.3609315","title":"Link Prediction in Multipartite Graphs With Application to Drug Repositioning Studies","display_name":"Link Prediction in Multipartite Graphs With Application to Drug Repositioning Studies","publication_year":2025,"publication_date":"2025-09-12","ids":{"openalex":"https://openalex.org/W4414162130","doi":"https://doi.org/10.1109/tcbbio.2025.3609315","pmid":"https://pubmed.ncbi.nlm.nih.gov/40938726"},"language":"en","primary_location":{"id":"doi:10.1109/tcbbio.2025.3609315","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbbio.2025.3609315","pdf_url":null,"source":{"id":"https://openalex.org/S5407042751","display_name":"IEEE Transactions on Computational Biology and Bioinformatics","issn_l":"2998-4165","issn":["2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12800381/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100420610","display_name":"Cheng Chen","orcid":"https://orcid.org/0009-0009-8134-983X"},"institutions":[{"id":"https://openalex.org/I75027704","display_name":"University of Tennessee at Knoxville","ror":"https://ror.org/020f3ap87","country_code":"US","type":"education","lineage":["https://openalex.org/I75027704"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Cheng Chen","raw_affiliation_strings":["Department of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN, USA","institution_ids":["https://openalex.org/I75027704"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067280372","display_name":"Stephen K. Grady","orcid":"https://orcid.org/0000-0002-1599-3338"},"institutions":[{"id":"https://openalex.org/I75027704","display_name":"University of Tennessee at Knoxville","ror":"https://ror.org/020f3ap87","country_code":"US","type":"education","lineage":["https://openalex.org/I75027704"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen K. Grady","raw_affiliation_strings":["Department of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN, USA","institution_ids":["https://openalex.org/I75027704"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033823994","display_name":"Levente Dojcsak","orcid":"https://orcid.org/0000-0002-7679-3268"},"institutions":[{"id":"https://openalex.org/I75027704","display_name":"University of Tennessee at Knoxville","ror":"https://ror.org/020f3ap87","country_code":"US","type":"education","lineage":["https://openalex.org/I75027704"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Levente Dojcsak","raw_affiliation_strings":["Department of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN, USA","institution_ids":["https://openalex.org/I75027704"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048121967","display_name":"Sally R. Ellingson","orcid":"https://orcid.org/0009-0004-3527-4041"},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sally R. Ellingson","raw_affiliation_strings":["Division of Biomedical Informatics, College of Medicine, University of Kentucky, Lexington, KY, USA"],"affiliations":[{"raw_affiliation_string":"Division of Biomedical Informatics, College of Medicine, University of Kentucky, Lexington, KY, USA","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011863644","display_name":"Michael A. Langston","orcid":"https://orcid.org/0000-0001-5945-5796"},"institutions":[{"id":"https://openalex.org/I75027704","display_name":"University of Tennessee at Knoxville","ror":"https://ror.org/020f3ap87","country_code":"US","type":"education","lineage":["https://openalex.org/I75027704"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael A. Langston","raw_affiliation_strings":["Department of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN, USA","institution_ids":["https://openalex.org/I75027704"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100420610"],"corresponding_institution_ids":["https://openalex.org/I75027704"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.25338373,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"22","issue":"6","first_page":"3055","last_page":"3064"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.995199978351593,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.995199978351593,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11273","display_name":"Advanced Graph Neural Networks","score":0.9724000096321106,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9692000150680542,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pairwise-comparison","display_name":"Pairwise comparison","score":0.7488999962806702},{"id":"https://openalex.org/keywords/bipartite-graph","display_name":"Bipartite graph","score":0.6665999889373779},{"id":"https://openalex.org/keywords/multipartite","display_name":"Multipartite","score":0.635200023651123},{"id":"https://openalex.org/keywords/link","display_name":"Link (geometry)","score":0.5145000219345093},{"id":"https://openalex.org/keywords/enumeration","display_name":"Enumeration","score":0.5002999901771545},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.41179999709129333}],"concepts":[{"id":"https://openalex.org/C184898388","wikidata":"https://www.wikidata.org/wiki/Q1435712","display_name":"Pairwise comparison","level":2,"score":0.7488999962806702},{"id":"https://openalex.org/C197657726","wikidata":"https://www.wikidata.org/wiki/Q174733","display_name":"Bipartite graph","level":3,"score":0.6665999889373779},{"id":"https://openalex.org/C166733315","wikidata":"https://www.wikidata.org/wiki/Q6934831","display_name":"Multipartite","level":4,"score":0.635200023651123},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.5202999711036682},{"id":"https://openalex.org/C2778753846","wikidata":"https://www.wikidata.org/wiki/Q6554239","display_name":"Link (geometry)","level":2,"score":0.5145000219345093},{"id":"https://openalex.org/C156340839","wikidata":"https://www.wikidata.org/wiki/Q2704791","display_name":"Enumeration","level":2,"score":0.5002999901771545},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.47760000824928284},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.41179999709129333},{"id":"https://openalex.org/C134119311","wikidata":"https://www.wikidata.org/wiki/Q913598","display_name":"Complete bipartite graph","level":4,"score":0.400299996137619},{"id":"https://openalex.org/C43214815","wikidata":"https://www.wikidata.org/wiki/Q7310987","display_name":"Reliability (semiconductor)","level":3,"score":0.39570000767707825},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.391400009393692},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3271999955177307},{"id":"https://openalex.org/C103637391","wikidata":"https://www.wikidata.org/wiki/Q5308921","display_name":"Drug repositioning","level":3,"score":0.31790000200271606},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.31150001287460327},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.31130000948905945},{"id":"https://openalex.org/C1173588","wikidata":"https://www.wikidata.org/wiki/Q6554294","display_name":"Link analysis","level":2,"score":0.305400013923645},{"id":"https://openalex.org/C88230418","wikidata":"https://www.wikidata.org/wiki/Q131476","display_name":"Graph theory","level":2,"score":0.2752000093460083},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.2662999927997589},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.2572999894618988}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1109/tcbbio.2025.3609315","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbbio.2025.3609315","pdf_url":null,"source":{"id":"https://openalex.org/S5407042751","display_name":"IEEE Transactions on Computational Biology and Bioinformatics","issn_l":"2998-4165","issn":["2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:40938726","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40938726","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on computational biology and bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:12800381","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12800381/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Comput Biol Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:12800381","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12800381/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Comput Biol Bioinform","raw_type":"Text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3114061957","display_name":null,"funder_award_id":"G17D112354237","funder_id":"https://openalex.org/F4320320835","funder_display_name":"Environmental Protection Agency"},{"id":"https://openalex.org/G3545296333","display_name":null,"funder_award_id":"R01HD092653","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6983318435","display_name":null,"funder_award_id":"P30CA177558","funder_id":"https://openalex.org/F4320333743","funder_display_name":"Markey Cancer Center, University of Kentucky"}],"funders":[{"id":"https://openalex.org/F4320317220","display_name":"National Energy Research Scientific Computing Center","ror":"https://ror.org/05v3mvq14"},{"id":"https://openalex.org/F4320320835","display_name":"Environmental Protection Agency","ror":"https://ror.org/05qbqeh37"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320333743","display_name":"Markey Cancer Center, University of Kentucky","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":60,"referenced_works":["https://openalex.org/W174753650","https://openalex.org/W1484040084","https://openalex.org/W1532875325","https://openalex.org/W1800166884","https://openalex.org/W1969124854","https://openalex.org/W1984084871","https://openalex.org/W1997754619","https://openalex.org/W2006571730","https://openalex.org/W2024829861","https://openalex.org/W2029667189","https://openalex.org/W2045204781","https://openalex.org/W2055043387","https://openalex.org/W2063342754","https://openalex.org/W2067643341","https://openalex.org/W2069320017","https://openalex.org/W2085050037","https://openalex.org/W2105668062","https://openalex.org/W2112937261","https://openalex.org/W2134967712","https://openalex.org/W2146341019","https://openalex.org/W2151036184","https://openalex.org/W2151697120","https://openalex.org/W2169589032","https://openalex.org/W2169678694","https://openalex.org/W2200017991","https://openalex.org/W2218939898","https://openalex.org/W2253261722","https://openalex.org/W2753460943","https://openalex.org/W2753953057","https://openalex.org/W2767891136","https://openalex.org/W2782382515","https://openalex.org/W2894695827","https://openalex.org/W2896002881","https://openalex.org/W2901527454","https://openalex.org/W2910185186","https://openalex.org/W2915806464","https://openalex.org/W2946586366","https://openalex.org/W3007743886","https://openalex.org/W3017154096","https://openalex.org/W3019535438","https://openalex.org/W3019793073","https://openalex.org/W3040062994","https://openalex.org/W3083358089","https://openalex.org/W3097658527","https://openalex.org/W3104537585","https://openalex.org/W3121001695","https://openalex.org/W3136198265","https://openalex.org/W3153939186","https://openalex.org/W3156260318","https://openalex.org/W3160021293","https://openalex.org/W4226111144","https://openalex.org/W4240563808","https://openalex.org/W4319983239","https://openalex.org/W4320909584","https://openalex.org/W4323045190","https://openalex.org/W4389239050","https://openalex.org/W4391788770","https://openalex.org/W4396584787","https://openalex.org/W4398249849","https://openalex.org/W4406698124"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2952287968","https://openalex.org/W2094758646","https://openalex.org/W1606665185","https://openalex.org/W2056683690","https://openalex.org/W2347515247","https://openalex.org/W2950685989","https://openalex.org/W2143516466"],"abstract_inverted_index":{"Developing":[0],"new":[1,47],"ethical":[2],"drugs":[3],"is":[4,113,130,168],"exceedingly":[5],"expensive":[6],"in":[7,52,56,120],"terms":[8],"of":[9,46,55,79,98,127,138,150,165],"both":[10],"time":[11],"and":[12,62,108,147,152],"resources.":[13],"A":[14],"single":[15],"drug":[16],"can":[17,67],"take":[18],"up":[19],"to":[20,23,25,30,43,70,82,115],"a":[21,32,96,105],"decade":[22],"bring":[24],"market,":[26],"with":[27,49,84,153],"costs":[28],"soaring":[29],"over":[31],"billion":[33],"dollars.":[34],"Drug":[35],"repositioning":[36,58],"has":[37],"thus":[38],"become":[39],"an":[40,121],"attractive":[41],"alternative":[42],"the":[44,53,163],"development":[45],"compounds,":[48],"growing":[50],"interest":[51],"use":[54],"silico":[57],"predictions.":[59],"Bipartite":[60],"graphs":[61],"efficient":[63,109],"biclique":[64],"enumeration":[65],"algorithms":[66],"be":[68],"used":[69],"study":[71],"drug-protein":[72],"or":[73,86,159],"other":[74],"pairwise":[75],"crucial":[76],"interactions.":[77],"Extensions":[78],"this":[80,103,128],"approach":[81],"datasets":[83],"three":[85,139],"more":[87],"divergent":[88],"data":[89],"types":[90],"have":[91],"been":[92],"hobbled,":[93],"however,":[94],"by":[95],"lack":[97],"effective":[99],"analytics.":[100],"To":[101],"address":[102],"shortcoming,":[104],"highly":[106],"innovative":[107],"graph":[110],"theoretical":[111],"technique":[112],"introduced":[114],"impute":[116],"potential":[117],"edges":[118,155,167],"(links)":[119],"arbitrary":[122],"multipartite":[123],"graph.":[124],"The":[125],"utility":[126],"method":[129],"demonstrated":[131],"on":[132],"five":[133],"tripartite":[134],"graphs,":[135],"each":[136,143],"comprised":[137],"partite":[140],"sets,":[141],"one":[142],"for":[144,162],"diseases,":[145],"drugs,":[146],"gene":[148],"products":[149],"interest,":[151],"interpartite":[154],"denoting":[156],"known":[157],"interactions":[158],"associations.":[160],"Evidence":[161],"reliability":[164],"imputed":[166],"also":[169],"reported.":[170]},"counts_by_year":[],"updated_date":"2026-04-09T08:11:56.329763","created_date":"2025-10-10T00:00:00"}