{"id":"https://openalex.org/W4409883098","doi":"https://doi.org/10.1109/tcbbio.2025.3564952","title":"GPU-Powered Evolutionary Auxiliary Multitasking for Fast SNP Interaction Detection","display_name":"GPU-Powered Evolutionary Auxiliary Multitasking for Fast SNP Interaction Detection","publication_year":2025,"publication_date":"2025-04-28","ids":{"openalex":"https://openalex.org/W4409883098","doi":"https://doi.org/10.1109/tcbbio.2025.3564952","pmid":"https://pubmed.ncbi.nlm.nih.gov/40811325"},"language":"en","primary_location":{"id":"doi:10.1109/tcbbio.2025.3564952","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbbio.2025.3564952","pdf_url":null,"source":{"id":"https://openalex.org/S5407042751","display_name":"IEEE Transactions on Computational Biology and Bioinformatics","issn_l":"2998-4165","issn":["2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039354723","display_name":"Fangting Li","orcid":"https://orcid.org/0000-0002-1483-1820"},"institutions":[{"id":"https://openalex.org/I9224756","display_name":"Northeastern University","ror":"https://ror.org/03awzbc87","country_code":"CN","type":"education","lineage":["https://openalex.org/I9224756"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Fangting Li","raw_affiliation_strings":["College of Computer Science and Engineering, Northeastern University, Shenyang, China","College of Computer Science and Engineering, Northeastern University, Shenyang, Liaoning, China"],"affiliations":[{"raw_affiliation_string":"College of Computer Science and Engineering, Northeastern University, Shenyang, China","institution_ids":["https://openalex.org/I9224756"]},{"raw_affiliation_string":"College of Computer Science and Engineering, Northeastern University, Shenyang, Liaoning, China","institution_ids":["https://openalex.org/I9224756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103672994","display_name":"Yin Ying","orcid":null},"institutions":[{"id":"https://openalex.org/I9224756","display_name":"Northeastern University","ror":"https://ror.org/03awzbc87","country_code":"CN","type":"education","lineage":["https://openalex.org/I9224756"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Yin","raw_affiliation_strings":["College of Computer Science and Engineering, Northeastern University, Shenyang, China","College of Computer Science and Engineering, Northeastern University, Shenyang, Liaoning, China"],"affiliations":[{"raw_affiliation_string":"College of Computer Science and Engineering, Northeastern University, Shenyang, China","institution_ids":["https://openalex.org/I9224756"]},{"raw_affiliation_string":"College of Computer Science and Engineering, Northeastern University, Shenyang, Liaoning, China","institution_ids":["https://openalex.org/I9224756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029403476","display_name":"Xin Wang","orcid":"https://orcid.org/0000-0002-3522-5627"},"institutions":[{"id":"https://openalex.org/I9224756","display_name":"Northeastern University","ror":"https://ror.org/03awzbc87","country_code":"CN","type":"education","lineage":["https://openalex.org/I9224756"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xin Wang","raw_affiliation_strings":["College of Computer Science and Engineering, Northeastern University, Shenyang, China","College of Computer Science and Engineering, Northeastern University, Shenyang, Liaoning, China"],"affiliations":[{"raw_affiliation_string":"College of Computer Science and Engineering, Northeastern University, Shenyang, China","institution_ids":["https://openalex.org/I9224756"]},{"raw_affiliation_string":"College of Computer Science and Engineering, Northeastern University, Shenyang, Liaoning, China","institution_ids":["https://openalex.org/I9224756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102845995","display_name":"Changyong Yu","orcid":null},"institutions":[{"id":"https://openalex.org/I9224756","display_name":"Northeastern University","ror":"https://ror.org/03awzbc87","country_code":"CN","type":"education","lineage":["https://openalex.org/I9224756"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Changyong Yu","raw_affiliation_strings":["College of Computer Science and Engineering, Northeastern University, Shenyang, China","College of Computer Science and Engineering, Northeastern University, Shenyang, Liaoning, China"],"affiliations":[{"raw_affiliation_string":"College of Computer Science and Engineering, Northeastern University, Shenyang, China","institution_ids":["https://openalex.org/I9224756"]},{"raw_affiliation_string":"College of Computer Science and Engineering, Northeastern University, Shenyang, Liaoning, China","institution_ids":["https://openalex.org/I9224756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101620559","display_name":"Yuhai Zhao","orcid":"https://orcid.org/0000-0002-1080-0859"},"institutions":[{"id":"https://openalex.org/I9224756","display_name":"Northeastern University","ror":"https://ror.org/03awzbc87","country_code":"CN","type":"education","lineage":["https://openalex.org/I9224756"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuhai Zhao","raw_affiliation_strings":["College of Computer Science and Engineering, Northeastern University, Shenyang, China","College of Computer Science and Engineering, Northeastern University, Shenyang, Liaoning, China"],"affiliations":[{"raw_affiliation_string":"College of Computer Science and Engineering, Northeastern University, Shenyang, China","institution_ids":["https://openalex.org/I9224756"]},{"raw_affiliation_string":"College of Computer Science and Engineering, Northeastern University, Shenyang, Liaoning, China","institution_ids":["https://openalex.org/I9224756"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002218208","display_name":"Ye Tian","orcid":"https://orcid.org/0000-0003-1772-8850"},"institutions":[{"id":"https://openalex.org/I91656880","display_name":"China Medical University","ror":"https://ror.org/032d4f246","country_code":"CN","type":"education","lineage":["https://openalex.org/I91656880"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ye Tian","raw_affiliation_strings":["Department of Orthopedics, Shengjing Hospital of China Medical University, Shenyang, China"],"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Shengjing Hospital of China Medical University, Shenyang, China","institution_ids":["https://openalex.org/I91656880"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5039354723"],"corresponding_institution_ids":["https://openalex.org/I9224756"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.09751397,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"22","issue":"4","first_page":"1662","last_page":"1673"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9822999835014343,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9822999835014343,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9736999869346619,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9560999870300293,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-multitasking","display_name":"Human multitasking","score":0.9502930641174316},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5900331139564514},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.22820788621902466},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.09031200408935547}],"concepts":[{"id":"https://openalex.org/C107418235","wikidata":"https://www.wikidata.org/wiki/Q1520565","display_name":"Human multitasking","level":2,"score":0.9502930641174316},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5900331139564514},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22820788621902466},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.09031200408935547}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/tcbbio.2025.3564952","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbbio.2025.3564952","pdf_url":null,"source":{"id":"https://openalex.org/S5407042751","display_name":"IEEE Transactions on Computational Biology and Bioinformatics","issn_l":"2998-4165","issn":["2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:40811325","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40811325","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on computational biology and bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Affordable and clean energy","id":"https://metadata.un.org/sdg/7","score":0.6000000238418579}],"awards":[{"id":"https://openalex.org/G1671140559","display_name":null,"funder_award_id":"92267206","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4262796517","display_name":null,"funder_award_id":"62401129","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7797178789","display_name":null,"funder_award_id":"62432003","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W1822695366","https://openalex.org/W1868492295","https://openalex.org/W1968536479","https://openalex.org/W1971299565","https://openalex.org/W1980991473","https://openalex.org/W2110808585","https://openalex.org/W2113784410","https://openalex.org/W2120423544","https://openalex.org/W2126105956","https://openalex.org/W2126964466","https://openalex.org/W2134783591","https://openalex.org/W2307163007","https://openalex.org/W2413527939","https://openalex.org/W2506176420","https://openalex.org/W2605140612","https://openalex.org/W2776317535","https://openalex.org/W2884533157","https://openalex.org/W2884728126","https://openalex.org/W2900352840","https://openalex.org/W2912348516","https://openalex.org/W2921687288","https://openalex.org/W2951212842","https://openalex.org/W2983670712","https://openalex.org/W2988685366","https://openalex.org/W3010321770","https://openalex.org/W3013264051","https://openalex.org/W3076243292","https://openalex.org/W3134616382","https://openalex.org/W3150264202","https://openalex.org/W3157359833","https://openalex.org/W3186153394","https://openalex.org/W3197383437","https://openalex.org/W4213217555","https://openalex.org/W4282940296","https://openalex.org/W4283817905","https://openalex.org/W4288060525","https://openalex.org/W4293240407","https://openalex.org/W4308169299","https://openalex.org/W4313413205","https://openalex.org/W4328007163","https://openalex.org/W4383302036","https://openalex.org/W4384024233","https://openalex.org/W4384080532","https://openalex.org/W4387425072","https://openalex.org/W4389328387","https://openalex.org/W4390992228","https://openalex.org/W4391100374","https://openalex.org/W4394805110","https://openalex.org/W4396867853","https://openalex.org/W4400260125","https://openalex.org/W4405187188","https://openalex.org/W4406238286"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W4388263628","https://openalex.org/W4242930893","https://openalex.org/W3140336604","https://openalex.org/W2488058330","https://openalex.org/W1988895983","https://openalex.org/W4237084280","https://openalex.org/W2886487614"],"abstract_inverted_index":{"Identifying":[0],"complex":[1,27],"interactions":[2],"among":[3],"millions":[4],"of":[5,26,208,221],"single":[6],"nucleotide":[7],"polymorphisms":[8],"(SNPs)":[9],"is":[10,201],"a":[11,83,124,139],"key":[12],"challenge":[13],"in":[14,65],"Genome-Wide":[15],"Association":[16],"Studies":[17],"(GWAS),":[18],"offering":[19],"crucial":[20],"insights":[21],"into":[22],"the":[23,77,98,150,157,162,176,183,205,209,218,222,254],"genetic":[24],"architecture":[25],"diseases.":[28],"Evolutionary":[29],"algorithm":[30,129],"(EA)-based":[31],"methods":[32,58],"have":[33],"gained":[34],"significant":[35],"attention":[36],"for":[37,131],"their":[38,114],"global":[39],"search":[40,159,165,206,249,255],"capabilities,":[41],"controllable":[42],"runtime,":[43],"and":[44,68,89,101,117,233,240,251],"multi-objective":[45],"optimization":[46,171],"potential.":[47],"However,":[48],"when":[49],"applied":[50],"to":[51,148,168,182,203],"high-dimensional":[52],"GWAS":[53],"datasets,":[54],"many":[55],"existing":[56],"EA-based":[57],"encounter":[59],"challenges":[60],"such":[61],"as":[62],"getting":[63],"trapped":[64],"local":[66,170],"optima":[67],"facing":[69],"high":[70,115],"computational":[71],"demands.":[72],"To":[73],"address":[74],"these":[75],"issues,":[76],"evolutionary":[78,126],"multitasking":[79,128],"(EMT)":[80],"paradigm":[81],"presents":[82],"promising":[84],"solution,":[85],"enhancing":[86],"population":[87],"diversity":[88],"convergence":[90],"speed":[91,252],"through":[92],"collaborative,":[93],"cross-task":[94],"knowledge":[95],"sharing.":[96],"Furthermore,":[97],"multi-tasking":[99],"framework":[100],"EA":[102],"can":[103,246],"be":[104],"seamlessly":[105],"deployed":[106],"across":[107,226],"multiple":[108,227],"Graphics":[109],"Processing":[110],"Units":[111],"(GPUs),":[112],"leveraging":[113],"parallelism":[116],"aggregated":[118],"memory":[119],"bandwidth.":[120],"Therefore,":[121],"we":[122],"introduce":[123],"GPU-powered":[125],"auxiliary":[127,146,163,177,193,210],"(GEAMT)":[130],"fast":[132],"SNP":[133],"interaction":[134],"detection.":[135],"GEAMT":[136,229,245],"first":[137],"constructs":[138],"main":[140,154,184,223],"task":[141,155,185,194],"along":[142],"with":[143],"several":[144],"low-dimensional":[145],"tasks":[147,164,178],"redefine":[149],"original":[151],"task.":[152,224],"The":[153,212],"explores":[156],"entire":[158],"space,":[160],"while":[161],"distinct":[166],"subspaces":[167,207],"enhance":[169,248],"capabilities.":[172],"In":[173],"each":[174],"iteration,":[175],"transfer":[179,189],"high-quality":[180],"information":[181,188],"via":[186],"an":[187,192],"mechanism.":[190],"Subsequently,":[191],"update":[195],"strategy":[196],"based":[197],"on":[198,237],"feature":[199],"regrouping":[200],"employed":[202],"switch":[204],"tasks.":[211],"final":[213],"results":[214],"are":[215],"derived":[216],"from":[217],"Pareto-optimal":[219],"solutions":[220],"Implemented":[225],"GPUs,":[228],"achieves":[230],"notable":[231],"scalability":[232],"efficiency.":[234],"Comprehensive":[235],"experiments":[236],"both":[238],"synthetic":[239],"real-world":[241],"datasets":[242],"demonstrate":[243],"that":[244],"significantly":[247],"accuracy":[250],"up":[253],"process.":[256]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}