{"id":"https://openalex.org/W4379382501","doi":"https://doi.org/10.1109/tcbb.2023.3282798","title":"Recurrence Network Analysis of Histopathological Images for the Detection of Invasive Ductal Carcinoma in Breast Cancer","display_name":"Recurrence Network Analysis of Histopathological Images for the Detection of Invasive Ductal Carcinoma in Breast Cancer","publication_year":2023,"publication_date":"2023-06-05","ids":{"openalex":"https://openalex.org/W4379382501","doi":"https://doi.org/10.1109/tcbb.2023.3282798","pmid":"https://pubmed.ncbi.nlm.nih.gov/37276118"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2023.3282798","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2023.3282798","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026639468","display_name":"Cheng\u2010Bang Chen","orcid":"https://orcid.org/0000-0003-0025-6447"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Cheng-Bang Chen","raw_affiliation_strings":["Department of Industrial and Systems Engineering, University of Miami, Coral Gables, FL, USA"],"raw_orcid":"https://orcid.org/0000-0003-0025-6447","affiliations":[{"raw_affiliation_string":"Department of Industrial and Systems Engineering, University of Miami, Coral Gables, FL, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114500332","display_name":"Yujie Wang","orcid":"https://orcid.org/0009-0003-0310-1077"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yujie Wang","raw_affiliation_strings":["Department of Industrial and Systems Engineering, University of Miami, Coral Gables, FL, USA"],"raw_orcid":"https://orcid.org/0009-0003-0310-1077","affiliations":[{"raw_affiliation_string":"Department of Industrial and Systems Engineering, University of Miami, Coral Gables, FL, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101209464","display_name":"Xuanya Fu","orcid":"https://orcid.org/0009-0002-0894-8704"},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xuanya Fu","raw_affiliation_strings":["Department of Industrial & Manufacturing Engineering, Penn State University, University Park, PA, USA"],"raw_orcid":"https://orcid.org/0009-0002-0894-8704","affiliations":[{"raw_affiliation_string":"Department of Industrial & Manufacturing Engineering, Penn State University, University Park, PA, USA","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062699999","display_name":"Hui Yang","orcid":"https://orcid.org/0000-0001-5997-6823"},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hui Yang","raw_affiliation_strings":["Department of Industrial & Manufacturing Engineering, Penn State University, University Park, PA, USA"],"raw_orcid":"https://orcid.org/0000-0001-5997-6823","affiliations":[{"raw_affiliation_string":"Department of Industrial & Manufacturing Engineering, Penn State University, University Park, PA, USA","institution_ids":["https://openalex.org/I130769515"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5026639468"],"corresponding_institution_ids":["https://openalex.org/I145608581"],"apc_list":null,"apc_paid":null,"fwci":1.8745,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.88225373,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"20","issue":"5","first_page":"3234","last_page":"3244"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10688","display_name":"Image and Signal Denoising Methods","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10824","display_name":"Image Retrieval and Classification Techniques","score":0.9876999855041504,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6365196704864502},{"id":"https://openalex.org/keywords/histopathological-examination","display_name":"Histopathological examination","score":0.5431209802627563},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5351119637489319},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.5282715559005737},{"id":"https://openalex.org/keywords/ductal-carcinoma","display_name":"Ductal carcinoma","score":0.5184023380279541},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4917786419391632},{"id":"https://openalex.org/keywords/invasive-ductal-carcinoma","display_name":"Invasive ductal carcinoma","score":0.45883670449256897},{"id":"https://openalex.org/keywords/wavelet","display_name":"Wavelet","score":0.4516512453556061},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.42692768573760986},{"id":"https://openalex.org/keywords/medical-imaging","display_name":"Medical imaging","score":0.4161769151687622},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.41097766160964966},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.34490418434143066},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.325983464717865},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2841310501098633},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.2778746485710144},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.07521495223045349}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6365196704864502},{"id":"https://openalex.org/C3020547009","wikidata":"https://www.wikidata.org/wiki/Q1070952","display_name":"Histopathological examination","level":2,"score":0.5431209802627563},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5351119637489319},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5282715559005737},{"id":"https://openalex.org/C2780862961","wikidata":"https://www.wikidata.org/wiki/Q5311598","display_name":"Ductal carcinoma","level":4,"score":0.5184023380279541},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4917786419391632},{"id":"https://openalex.org/C3020375857","wikidata":"https://www.wikidata.org/wiki/Q1671685","display_name":"Invasive ductal carcinoma","level":4,"score":0.45883670449256897},{"id":"https://openalex.org/C47432892","wikidata":"https://www.wikidata.org/wiki/Q831390","display_name":"Wavelet","level":2,"score":0.4516512453556061},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.42692768573760986},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.4161769151687622},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.41097766160964966},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.34490418434143066},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.325983464717865},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2841310501098633},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2778746485710144},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.07521495223045349},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018270","descriptor_name":"Carcinoma, Ductal, Breast","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D018270","descriptor_name":"Carcinoma, Ductal, Breast","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D018270","descriptor_name":"Carcinoma, Ductal, Breast","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D018270","descriptor_name":"Carcinoma, Ductal, Breast","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D018270","descriptor_name":"Carcinoma, Ductal, Breast","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D018270","descriptor_name":"Carcinoma, Ductal, Breast","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tcbb.2023.3282798","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2023.3282798","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:37276118","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37276118","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5799999833106995,"display_name":"Peace, Justice and strong institutions","id":"https://metadata.un.org/sdg/16"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W202858203","https://openalex.org/W1661633619","https://openalex.org/W1835905048","https://openalex.org/W1966720965","https://openalex.org/W1981510969","https://openalex.org/W2014705735","https://openalex.org/W2025244431","https://openalex.org/W2036313666","https://openalex.org/W2041376115","https://openalex.org/W2053953532","https://openalex.org/W2062177968","https://openalex.org/W2080194173","https://openalex.org/W2081681829","https://openalex.org/W2085226702","https://openalex.org/W2099593264","https://openalex.org/W2105811964","https://openalex.org/W2118570688","https://openalex.org/W2132911732","https://openalex.org/W2134993189","https://openalex.org/W2138786254","https://openalex.org/W2143093135","https://openalex.org/W2164347644","https://openalex.org/W2302302587","https://openalex.org/W2393733645","https://openalex.org/W2418166239","https://openalex.org/W2504150216","https://openalex.org/W2514611596","https://openalex.org/W2523539920","https://openalex.org/W2564170690","https://openalex.org/W2591620585","https://openalex.org/W2888995381","https://openalex.org/W2989297316","https://openalex.org/W2994910508","https://openalex.org/W2999211107","https://openalex.org/W3081268292","https://openalex.org/W3123833307","https://openalex.org/W3131926350","https://openalex.org/W3213783748","https://openalex.org/W4200018954","https://openalex.org/W4210314683","https://openalex.org/W4292533917","https://openalex.org/W4294926720"],"related_works":["https://openalex.org/W4308631024","https://openalex.org/W2089969489","https://openalex.org/W2255866468","https://openalex.org/W3029777594","https://openalex.org/W2360615271","https://openalex.org/W2896408981","https://openalex.org/W4210639371","https://openalex.org/W2391796841","https://openalex.org/W4236264508","https://openalex.org/W4402649093"],"abstract_inverted_index":{"The":[0,128,183],"histopathological":[1,48,110,139,167],"image":[2,191],"analysis":[3,72,131,159],"is":[4,25],"one":[5],"of":[6,41,61,108,138,147],"the":[7,47,86,90,95,105,109,135,143,180],"most":[8],"crucial":[9],"diagnostic":[10],"procedures":[11],"to":[12,56,84,103,161,176,190],"identify":[13,163],"Invasive":[14],"ductal":[15],"carcinoma":[16],"(IDC)":[17],"in":[18,46,89,166,179],"breast":[19],"cancers.":[20],"However,":[21,50],"this":[22],"diagnosis":[23],"process":[24],"currently":[26],"time-consuming":[27],"and":[28,141],"heavily":[29],"dependent":[30],"on":[31],"human":[32],"expertise.":[33],"Prior":[34],"research":[35,154],"has":[36,53],"shown":[37],"that":[38],"different":[39],"degrees":[40],"tumors":[42],"present":[43],"various":[44],"microstructures":[45,62,137],"images.":[49,91,111],"very":[51],"little":[52],"been":[54],"done":[55],"utilize":[57,81],"spatial":[58,124,157],"recurrence":[59,71,100,106,125,130,158],"features":[60,126],"for":[63,74,169,193],"identifying":[64],"IDC.":[65],"This":[66,153],"paper":[67],"presents":[68],"a":[69,98,156,173],"novel":[70],"methodology":[73,160,185],"automatic":[75],"image-guided":[76],"IDC":[77,116,144,164],"detection.":[78],"We":[79],"first":[80],"wavelet":[82],"decomposition":[83],"delineate":[85],"subtle":[87],"information":[88],"Then,":[92],"we":[93,113],"model":[94],"patches":[96],"with":[97,123],"weighted":[99],"network":[101],"approach":[102],"characterize":[104,134],"patterns":[107],"Finally,":[112],"develop":[114],"automated":[115],"detection":[117,145],"models":[118,132],"leveraging":[119],"machine":[120],"learning":[121],"methods":[122],"extracted.":[127],"developed":[129,155],"successfully":[133],"complex":[136],"images":[140,168],"achieve":[142],"performances":[146],"at":[148],"least":[149],"AUC":[150],"=":[151],"0.96.":[152],"effectively":[162],"regions":[165],"BC.":[170],"It":[171],"shows":[172],"high":[174],"potential":[175],"assist":[177],"physicians":[178],"decision-making":[181],"process.":[182],"proposed":[184],"can":[186],"further":[187],"be":[188],"applicable":[189],"processing":[192],"other":[194],"medical":[195],"or":[196],"biological":[197],"applications.":[198]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}