{"id":"https://openalex.org/W4310465624","doi":"https://doi.org/10.1109/tcbb.2022.3225300","title":"Improved Computational Drug-Repositioning by Self-Paced Non-Negative Matrix Tri-Factorization","display_name":"Improved Computational Drug-Repositioning by Self-Paced Non-Negative Matrix Tri-Factorization","publication_year":2022,"publication_date":"2022-11-29","ids":{"openalex":"https://openalex.org/W4310465624","doi":"https://doi.org/10.1109/tcbb.2022.3225300","pmid":"https://pubmed.ncbi.nlm.nih.gov/36445996"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2022.3225300","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2022.3225300","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103148242","display_name":"Qi Dang","orcid":"https://orcid.org/0000-0003-1947-4997"},"institutions":[{"id":"https://openalex.org/I111950717","display_name":"Macau University of Science and Technology","ror":"https://ror.org/03jqs2n27","country_code":"MO","type":"education","lineage":["https://openalex.org/I111950717","https://openalex.org/I4391767947"]}],"countries":["MO"],"is_corresponding":true,"raw_author_name":"Qi Dang","raw_affiliation_strings":["Faculty of Innovation Engineering, Macau University of Science and Technology, Taipa, Macau, China"],"affiliations":[{"raw_affiliation_string":"Faculty of Innovation Engineering, Macau University of Science and Technology, Taipa, Macau, China","institution_ids":["https://openalex.org/I111950717"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059383536","display_name":"Yong Liang","orcid":"https://orcid.org/0000-0003-2403-1971"},"institutions":[{"id":"https://openalex.org/I4210136793","display_name":"Peng Cheng Laboratory","ror":"https://ror.org/03qdqbt06","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210136793"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yong Liang","raw_affiliation_strings":["Peng Cheng Laboratory, Shenzhen, Guangdong, China"],"affiliations":[{"raw_affiliation_string":"Peng Cheng Laboratory, Shenzhen, Guangdong, China","institution_ids":["https://openalex.org/I4210136793"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110092597","display_name":"Dong Ouyang","orcid":"https://orcid.org/0000-0003-3756-6748"},"institutions":[{"id":"https://openalex.org/I111950717","display_name":"Macau University of Science and Technology","ror":"https://ror.org/03jqs2n27","country_code":"MO","type":"education","lineage":["https://openalex.org/I111950717","https://openalex.org/I4391767947"]}],"countries":["MO"],"is_corresponding":false,"raw_author_name":"Dong Ouyang","raw_affiliation_strings":["Faculty of Innovation Engineering, Macau University of Science and Technology, Taipa, Macau, China"],"affiliations":[{"raw_affiliation_string":"Faculty of Innovation Engineering, Macau University of Science and Technology, Taipa, Macau, China","institution_ids":["https://openalex.org/I111950717"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025130985","display_name":"Rui Miao","orcid":"https://orcid.org/0000-0002-1800-454X"},"institutions":[{"id":"https://openalex.org/I182386381","display_name":"Zunyi Medical University","ror":"https://ror.org/00g5b0g93","country_code":"CN","type":"education","lineage":["https://openalex.org/I182386381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rui Miao","raw_affiliation_strings":["Basic Teaching Department, Zunyi Medical University, Zhuhai, Guangdong, China"],"affiliations":[{"raw_affiliation_string":"Basic Teaching Department, Zunyi Medical University, Zhuhai, Guangdong, China","institution_ids":["https://openalex.org/I182386381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020303638","display_name":"Caijin Ling","orcid":"https://orcid.org/0000-0002-4574-886X"},"institutions":[{"id":"https://openalex.org/I111950717","display_name":"Macau University of Science and Technology","ror":"https://ror.org/03jqs2n27","country_code":"MO","type":"education","lineage":["https://openalex.org/I111950717","https://openalex.org/I4391767947"]}],"countries":["MO"],"is_corresponding":false,"raw_author_name":"Caijin Ling","raw_affiliation_strings":["Faculty of Innovation Engineering, Macau University of Science and Technology, Taipa, Macau, China"],"affiliations":[{"raw_affiliation_string":"Faculty of Innovation Engineering, Macau University of Science and Technology, Taipa, Macau, China","institution_ids":["https://openalex.org/I111950717"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100394460","display_name":"Xiaoying Liu","orcid":"https://orcid.org/0000-0002-9359-1457"},"institutions":[{"id":"https://openalex.org/I32820368","display_name":"Guangdong Polytechnic of Science and Technology","ror":"https://ror.org/01wq2p249","country_code":"CN","type":"education","lineage":["https://openalex.org/I32820368"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoying Liu","raw_affiliation_strings":["Computer Engineering Technical College, Guangdong Polytechnic of Science and Technology, Zhuhai, Guangdong, China"],"affiliations":[{"raw_affiliation_string":"Computer Engineering Technical College, Guangdong Polytechnic of Science and Technology, Zhuhai, Guangdong, China","institution_ids":["https://openalex.org/I32820368"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043262479","display_name":"Shengli Xie","orcid":"https://orcid.org/0000-0003-2041-5214"},"institutions":[{"id":"https://openalex.org/I4210107815","display_name":"Guangdong-Hongkong-Macau Joint Laboratory of Collaborative Innovation for Environmental Quality","ror":"https://ror.org/02gwsx029","country_code":"CN","type":"education","lineage":["https://openalex.org/I111950717","https://openalex.org/I159948400","https://openalex.org/I200769079","https://openalex.org/I4210107815","https://openalex.org/I4210144285","https://openalex.org/I4391767947"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shengli Xie","raw_affiliation_strings":["Guangdong-HongKong-Macao Joint Laboratory for Smart Discrete Manufacturing, Guangzhou, Guangdong, China"],"affiliations":[{"raw_affiliation_string":"Guangdong-HongKong-Macao Joint Laboratory for Smart Discrete Manufacturing, Guangzhou, Guangdong, China","institution_ids":["https://openalex.org/I4210107815"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5103148242"],"corresponding_institution_ids":["https://openalex.org/I111950717"],"apc_list":null,"apc_paid":null,"fwci":0.4383,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.65930956,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":96},"biblio":{"volume":"20","issue":"3","first_page":"1953","last_page":"1962"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9950000047683716,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6958969831466675},{"id":"https://openalex.org/keywords/matrix-decomposition","display_name":"Matrix decomposition","score":0.6589873433113098},{"id":"https://openalex.org/keywords/factorization","display_name":"Factorization","score":0.5554608702659607},{"id":"https://openalex.org/keywords/weighting","display_name":"Weighting","score":0.5459900498390198},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5361288785934448},{"id":"https://openalex.org/keywords/code","display_name":"Code (set theory)","score":0.5259911417961121},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.48915722966194153},{"id":"https://openalex.org/keywords/non-negative-matrix-factorization","display_name":"Non-negative matrix factorization","score":0.4656440019607544},{"id":"https://openalex.org/keywords/quality","display_name":"Quality (philosophy)","score":0.4426478147506714},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.434188574552536},{"id":"https://openalex.org/keywords/drug-repositioning","display_name":"Drug repositioning","score":0.42484840750694275},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.3438130021095276},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.33547350764274597},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.22558417916297913},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.11172541975975037},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.10898596048355103}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6958969831466675},{"id":"https://openalex.org/C42355184","wikidata":"https://www.wikidata.org/wiki/Q1361088","display_name":"Matrix decomposition","level":3,"score":0.6589873433113098},{"id":"https://openalex.org/C187834632","wikidata":"https://www.wikidata.org/wiki/Q188804","display_name":"Factorization","level":2,"score":0.5554608702659607},{"id":"https://openalex.org/C183115368","wikidata":"https://www.wikidata.org/wiki/Q856577","display_name":"Weighting","level":2,"score":0.5459900498390198},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5361288785934448},{"id":"https://openalex.org/C2776760102","wikidata":"https://www.wikidata.org/wiki/Q5139990","display_name":"Code (set theory)","level":3,"score":0.5259911417961121},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.48915722966194153},{"id":"https://openalex.org/C152671427","wikidata":"https://www.wikidata.org/wiki/Q10843505","display_name":"Non-negative matrix factorization","level":4,"score":0.4656440019607544},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.4426478147506714},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.434188574552536},{"id":"https://openalex.org/C103637391","wikidata":"https://www.wikidata.org/wiki/Q5308921","display_name":"Drug repositioning","level":3,"score":0.42484840750694275},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.3438130021095276},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.33547350764274597},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.22558417916297913},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11172541975975037},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.10898596048355103},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0},{"id":"https://openalex.org/C158693339","wikidata":"https://www.wikidata.org/wiki/Q190524","display_name":"Eigenvalues and eigenvectors","level":2,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000076722","descriptor_name":"Drug Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000076722","descriptor_name":"Drug Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000076722","descriptor_name":"Drug Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tcbb.2022.3225300","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2022.3225300","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:36445996","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36445996","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6600000262260437}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W17583692","https://openalex.org/W183401690","https://openalex.org/W880548201","https://openalex.org/W1971106435","https://openalex.org/W1974095883","https://openalex.org/W2005817231","https://openalex.org/W2114445615","https://openalex.org/W2132984949","https://openalex.org/W2138337932","https://openalex.org/W2139736926","https://openalex.org/W2151357092","https://openalex.org/W2183717576","https://openalex.org/W2184981123","https://openalex.org/W2209906241","https://openalex.org/W2256388387","https://openalex.org/W2301625241","https://openalex.org/W2331947132","https://openalex.org/W2540547679","https://openalex.org/W2576544908","https://openalex.org/W2586149740","https://openalex.org/W2682265686","https://openalex.org/W2785145011","https://openalex.org/W2793951981","https://openalex.org/W2799845593","https://openalex.org/W2804488518","https://openalex.org/W2887766329","https://openalex.org/W2910137768","https://openalex.org/W2946099214","https://openalex.org/W2952332592","https://openalex.org/W2953544853","https://openalex.org/W2960557205","https://openalex.org/W2988260770","https://openalex.org/W3010839774","https://openalex.org/W3022121690","https://openalex.org/W3035015656","https://openalex.org/W3044334750","https://openalex.org/W3165796371","https://openalex.org/W4211067395","https://openalex.org/W4213265077","https://openalex.org/W6600722119","https://openalex.org/W6679390333","https://openalex.org/W6686420396"],"related_works":["https://openalex.org/W2127243424","https://openalex.org/W4390394189","https://openalex.org/W2037504162","https://openalex.org/W2792706544","https://openalex.org/W1568451138","https://openalex.org/W2539013788","https://openalex.org/W2156699640","https://openalex.org/W2045265907","https://openalex.org/W2972997031","https://openalex.org/W2075222291"],"abstract_inverted_index":{"Drug":[0],"repositioning":[1],"(DR)":[2],"is":[3],"a":[4,67,77,85,106,152],"strategy":[5],"to":[6,64,75,117,139,157],"find":[7],"new":[8],"targets":[9],"for":[10],"existing":[11],"drugs,":[12],"which":[13,92,147],"plays":[14],"an":[15],"important":[16],"role":[17],"in":[18,38,142,194],"reducing":[19],"the":[20,30,39,54,72,119,123,126,128,143,159,163,184],"costs,":[21],"time,":[22],"and":[23,103,175,189,199],"risk":[24],"of":[25,41,96,122,162,172],"traditional":[26],"drug":[27,195],"development.":[28],"Recently,":[29],"matrix":[31,88,111],"factorization":[32],"approach":[33],"has":[34],"been":[35],"widely":[36],"used":[37],"field":[40],"DR":[42],"prediction.":[43],"Nevertheless,":[44],"there":[45],"are":[46,202],"still":[47],"two":[48,169],"challenges:":[49],"1)":[50],"Learning":[51],"ability":[52,121],"deficiencies,":[53],"model":[55,73,130],"cannot":[56],"accurately":[57],"predict":[58],"more":[59,115],"potential":[60],"associations.":[61],"2)":[62],"Easy":[63],"fall":[65],"into":[66,105,134,151],"bad":[68,153],"local":[69,154],"optimal":[70,155],"solution,":[71],"tends":[74],"get":[76],"suboptimal":[78],"result.":[79],"In":[80,125],"this":[81],"study,":[82],"we":[83],"propose":[84],"self-paced":[86],"non-negative":[87,110],"tri-factorization":[89],"(SPLNMTF)":[90],"model,":[91],"integrates":[93],"three":[94],"types":[95],"different":[97],"biological":[98],"data":[99,198],"from":[100,136],"patients,":[101],"genes,":[102],"drugs":[104],"heterogeneous":[107],"network":[108],"through":[109],"tri-factorization,":[112],"thereby":[113],"learning":[114,120],"information":[116],"improve":[118,158],"model.":[124,164],"meantime,":[127],"SPLNMTF":[129,182],"sequentially":[131],"includes":[132],"samples":[133],"training":[135],"easy":[137],"(high-quality)":[138],"complex":[140],"(low-quality)":[141],"soft":[144],"weighting":[145],"way,":[146],"effectively":[148],"alleviates":[149],"falling":[150],"solution":[156],"prediction":[160,192],"performance":[161,193],"The":[165,197],"experimental":[166],"results":[167],"on":[168],"real":[170],"datasets":[171],"ovarian":[173],"cancer":[174],"acute":[176],"myeloid":[177],"leukemia":[178],"(AML)":[179],"show":[180],"that":[181],"outperforms":[183],"other":[185],"eight":[186],"state-of-the-art":[187],"models":[188],"gets":[190],"better":[191],"repositioning.":[196],"source":[200],"code":[201],"available":[203],"at:":[204],"https://github.com/qi0906/SPLNMTF.":[205]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}