{"id":"https://openalex.org/W4210602267","doi":"https://doi.org/10.1109/tcbb.2022.3146176","title":"MSF-LRR: Multi-Similarity Information Fusion Through Low-Rank Representation to Predict Disease-Associated Microbes","display_name":"MSF-LRR: Multi-Similarity Information Fusion Through Low-Rank Representation to Predict Disease-Associated Microbes","publication_year":2022,"publication_date":"2022-01-27","ids":{"openalex":"https://openalex.org/W4210602267","doi":"https://doi.org/10.1109/tcbb.2022.3146176","pmid":"https://pubmed.ncbi.nlm.nih.gov/35085090"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2022.3146176","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2022.3146176","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043","2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073144090","display_name":"Jin\u2010Xing Liu","orcid":"https://orcid.org/0000-0001-6104-2149"},"institutions":[{"id":"https://openalex.org/I202126657","display_name":"Qufu Normal University","ror":"https://ror.org/03ceheh96","country_code":"CN","type":"education","lineage":["https://openalex.org/I202126657"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jin-Xing Liu","raw_affiliation_strings":["School of Computer Science, Qufu Normal University, Rizhao, Shandong, China"],"raw_orcid":"https://orcid.org/0000-0001-6104-2149","affiliations":[{"raw_affiliation_string":"School of Computer Science, Qufu Normal University, Rizhao, Shandong, China","institution_ids":["https://openalex.org/I202126657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018925936","display_name":"Meng-Meng Yin","orcid":"https://orcid.org/0000-0001-6143-023X"},"institutions":[{"id":"https://openalex.org/I202126657","display_name":"Qufu Normal University","ror":"https://ror.org/03ceheh96","country_code":"CN","type":"education","lineage":["https://openalex.org/I202126657"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Meng-Meng Yin","raw_affiliation_strings":["School of Computer Science, Qufu Normal University, Rizhao, Shandong, China"],"raw_orcid":"https://orcid.org/0000-0001-6143-023X","affiliations":[{"raw_affiliation_string":"School of Computer Science, Qufu Normal University, Rizhao, Shandong, China","institution_ids":["https://openalex.org/I202126657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026569643","display_name":"Ying-Lian Gao","orcid":"https://orcid.org/0000-0003-0483-5622"},"institutions":[{"id":"https://openalex.org/I202126657","display_name":"Qufu Normal University","ror":"https://ror.org/03ceheh96","country_code":"CN","type":"education","lineage":["https://openalex.org/I202126657"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying-Lian Gao","raw_affiliation_strings":["Qufu Normal University Library, Qufu Normal University, Rizhao, Shandong, China"],"raw_orcid":"https://orcid.org/0000-0003-0483-5622","affiliations":[{"raw_affiliation_string":"Qufu Normal University Library, Qufu Normal University, Rizhao, Shandong, China","institution_ids":["https://openalex.org/I202126657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007539735","display_name":"Junliang Shang","orcid":"https://orcid.org/0000-0002-8488-2228"},"institutions":[{"id":"https://openalex.org/I202126657","display_name":"Qufu Normal University","ror":"https://ror.org/03ceheh96","country_code":"CN","type":"education","lineage":["https://openalex.org/I202126657"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junliang Shang","raw_affiliation_strings":["School of Computer Science, Qufu Normal University, Rizhao, Shandong, China"],"raw_orcid":"https://orcid.org/0000-0002-8488-2228","affiliations":[{"raw_affiliation_string":"School of Computer Science, Qufu Normal University, Rizhao, Shandong, China","institution_ids":["https://openalex.org/I202126657"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064185915","display_name":"Chun-Hou Zheng","orcid":"https://orcid.org/0000-0002-2695-1926"},"institutions":[{"id":"https://openalex.org/I202126657","display_name":"Qufu Normal University","ror":"https://ror.org/03ceheh96","country_code":"CN","type":"education","lineage":["https://openalex.org/I202126657"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chun-Hou Zheng","raw_affiliation_strings":["School of Computer Science, Qufu Normal University, Rizhao, Shandong, China"],"raw_orcid":"https://orcid.org/0000-0002-2695-1926","affiliations":[{"raw_affiliation_string":"School of Computer Science, Qufu Normal University, Rizhao, Shandong, China","institution_ids":["https://openalex.org/I202126657"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I202126657"],"apc_list":null,"apc_paid":null,"fwci":1.4893,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.8161658,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"20","issue":"1","first_page":"534","last_page":"543"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.992900013923645,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9894999861717224,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.6909705996513367},{"id":"https://openalex.org/keywords/rank","display_name":"Rank (graph theory)","score":0.5657045841217041},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.5568761825561523},{"id":"https://openalex.org/keywords/representation","display_name":"Representation (politics)","score":0.5555854439735413},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5094309449195862},{"id":"https://openalex.org/keywords/perspective","display_name":"Perspective (graphical)","score":0.5058298110961914},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.45249056816101074},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.42284929752349854},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.37258055806159973},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.36469537019729614},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2898722290992737},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2574714422225952},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.20781147480010986},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.0734281837940216}],"concepts":[{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.6909705996513367},{"id":"https://openalex.org/C164226766","wikidata":"https://www.wikidata.org/wiki/Q7293202","display_name":"Rank (graph theory)","level":2,"score":0.5657045841217041},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5568761825561523},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.5555854439735413},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5094309449195862},{"id":"https://openalex.org/C12713177","wikidata":"https://www.wikidata.org/wiki/Q1900281","display_name":"Perspective (graphical)","level":2,"score":0.5058298110961914},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.45249056816101074},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.42284929752349854},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.37258055806159973},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.36469537019729614},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2898722290992737},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2574714422225952},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20781147480010986},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0734281837940216},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000076662","descriptor_name":"Host Microbial Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000076662","descriptor_name":"Host Microbial Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000076662","descriptor_name":"Host Microbial Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tcbb.2022.3146176","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2022.3146176","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043","2998-4165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:35085090","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35085090","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.4300000071525574}],"awards":[{"id":"https://openalex.org/G1350247206","display_name":null,"funder_award_id":"62172254","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G247010507","display_name":null,"funder_award_id":"61873001","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5609717784","display_name":"\u57fa\u4e8e\u4f4e\u79e9\u548c\u56fe\u6b63\u5219\u7ea6\u675f\u7684\u77e9\u9635\u5206\u89e3\u65b9\u6cd5\u7814\u7a76\u53ca\u5728\u764c\u75c7\u591a\u7ec4\u5b66\u6570\u636e\u4e2d\u7684\u5e94\u7528","funder_award_id":"61872220","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W935252537","https://openalex.org/W1530034318","https://openalex.org/W1921707153","https://openalex.org/W1967087625","https://openalex.org/W2012606594","https://openalex.org/W2017153096","https://openalex.org/W2030108859","https://openalex.org/W2041073071","https://openalex.org/W2053277762","https://openalex.org/W2103972604","https://openalex.org/W2141222510","https://openalex.org/W2142678478","https://openalex.org/W2145336165","https://openalex.org/W2146341019","https://openalex.org/W2152970345","https://openalex.org/W2262946425","https://openalex.org/W2311203695","https://openalex.org/W2312962182","https://openalex.org/W2322763599","https://openalex.org/W2343107734","https://openalex.org/W2462108616","https://openalex.org/W2567465856","https://openalex.org/W2590194234","https://openalex.org/W2737240357","https://openalex.org/W2739664659","https://openalex.org/W2765928324","https://openalex.org/W2765950793","https://openalex.org/W2776589520","https://openalex.org/W2803434593","https://openalex.org/W2896829849","https://openalex.org/W2901312953","https://openalex.org/W2913027027","https://openalex.org/W2918544540","https://openalex.org/W2918882492","https://openalex.org/W2922817064","https://openalex.org/W2966354805","https://openalex.org/W3006879221","https://openalex.org/W3048259272","https://openalex.org/W4211248483"],"related_works":["https://openalex.org/W2899084033","https://openalex.org/W2149537132","https://openalex.org/W2018871932","https://openalex.org/W641279757","https://openalex.org/W370975646","https://openalex.org/W1670566515","https://openalex.org/W4242022592","https://openalex.org/W596972243","https://openalex.org/W4313230280","https://openalex.org/W69751022"],"abstract_inverted_index":{"An":[0],"Increase":[1],"in":[2,152],"microbial":[3],"activity":[4],"is":[5,43,81,127,142,186],"shown":[6],"to":[7,26,50,55,83,105,129,144,197],"be":[8],"intimately":[9],"connected":[10],"with":[11,168],"the":[12,17,90,94,99,107,111,122,137,163,180],"pathogenesis":[13],"of":[14,19,68,72,98,124,140,162,190],"diseases.":[15],"Considering":[16,59],"expense":[18],"traditional":[20],"verification":[21],"methods,":[22],"researchers":[23],"are":[24,77],"working":[25],"develop":[27],"high-efficiency":[28],"methods":[29,63],"for":[30,110],"detecting":[31],"potential":[32,191],"disease-related":[33,57],"microbes.":[34,58],"In":[35,183],"this":[36],"article,":[37],"a":[38,102,116,135,187],"new":[39],"prediction":[40,112,118],"method,":[41],"MSF-LRR,":[42],"established,":[44],"which":[45],"uses":[46],"Low-Rank":[47],"Representation":[48],"(LRR)":[49],"perform":[51],"multi-similarity":[52],"information":[53,108],"fusion":[54],"predict":[56,130],"that":[60,120],"most":[61],"existing":[62,146],"only":[64],"use":[65],"one":[66],"class":[67],"similarity,":[69],"three":[70],"classes":[71],"microbe":[73],"and":[74,160,171,194,200],"disease":[75],"similarity":[76,87],"added.":[78],"Then,":[79],"LRR":[80],"used":[82,109],"obtain":[84],"low-rank":[85,96],"structural":[86],"information.":[88],"Additionally,":[89],"method":[91,119],"adaptively":[92],"extracts":[93],"local":[95],"structure":[97],"data":[100],"from":[101],"global":[103],"perspective,":[104],"make":[106],"more":[113],"effective.":[114],"Finally,":[115],"neighbor-based":[117],"utilizes":[121],"concept":[123],"collaborative":[125],"filtering":[126],"applied":[128],"unknown":[131],"microbe-disease":[132,192],"pairs.":[133],"As":[134],"result,":[136],"AUC":[138],"value":[139],"MSF-LRR":[141,185],"superior":[143],"other":[145],"algorithms":[147],"under":[148],"5-fold":[149],"cross-validation.":[150],"Furthermore,":[151],"case":[153],"studies,":[154],"excluding":[155],"originally":[156],"known":[157],"associations,":[158],"16":[159],"19":[161],"top":[164],"20":[165],"microbes":[166],"associated":[167],"Bacterial":[169],"Vaginosis":[170],"Irritable":[172],"Bowel":[173],"Syndrome,":[174],"respectively,":[175],"have":[176],"been":[177],"confirmed":[178],"by":[179],"recent":[181],"literature.":[182],"summary,":[184],"good":[188],"predictor":[189],"associations":[193],"can":[195],"contribute":[196],"drug":[198],"discovery":[199],"biological":[201],"research.":[202]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":2}],"updated_date":"2026-07-30T17:31:21.811387","created_date":"2025-10-10T00:00:00"}