{"id":"https://openalex.org/W3157631795","doi":"https://doi.org/10.1109/tcbb.2021.3076422","title":"PAN: Personalized Annotation-Based Networks for the Prediction of Breast Cancer Relapse","display_name":"PAN: Personalized Annotation-Based Networks for the Prediction of Breast Cancer Relapse","publication_year":2021,"publication_date":"2021-04-28","ids":{"openalex":"https://openalex.org/W3157631795","doi":"https://doi.org/10.1109/tcbb.2021.3076422","mag":"3157631795","pmid":"https://pubmed.ncbi.nlm.nih.gov/33909569"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2021.3076422","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2021.3076422","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100705489","display_name":"Thin Nguyen","orcid":"https://orcid.org/0000-0003-3467-8963"},"institutions":[{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Thin Nguyen","raw_affiliation_strings":["Applied Artificial Intelligence Institute, Deakin University, Burwood, VIC, Australia"],"affiliations":[{"raw_affiliation_string":"Applied Artificial Intelligence Institute, Deakin University, Burwood, VIC, Australia","institution_ids":["https://openalex.org/I149704539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087978393","display_name":"Sam Lee","orcid":"https://orcid.org/0000-0002-6805-4051"},"institutions":[{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Samuel C. Lee","raw_affiliation_strings":["Applied Artificial Intelligence Institute, Deakin University, Burwood, VIC, Australia"],"affiliations":[{"raw_affiliation_string":"Applied Artificial Intelligence Institute, Deakin University, Burwood, VIC, Australia","institution_ids":["https://openalex.org/I149704539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100780236","display_name":"Thomas P. Quinn","orcid":"https://orcid.org/0000-0003-0286-6329"},"institutions":[{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Thomas P. Quinn","raw_affiliation_strings":["Applied Artificial Intelligence Institute, Deakin University, Burwood, VIC, Australia"],"affiliations":[{"raw_affiliation_string":"Applied Artificial Intelligence Institute, Deakin University, Burwood, VIC, Australia","institution_ids":["https://openalex.org/I149704539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066650734","display_name":"Buu Truong","orcid":"https://orcid.org/0000-0003-0043-0812"},"institutions":[{"id":"https://openalex.org/I170239107","display_name":"University of South Australia","ror":"https://ror.org/01p93h210","country_code":"AU","type":"education","lineage":["https://openalex.org/I170239107"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Buu Truong","raw_affiliation_strings":["School of Information Technology and Mathematical Sciences, University of South Australia, Adelaide, SA, Australia"],"affiliations":[{"raw_affiliation_string":"School of Information Technology and Mathematical Sciences, University of South Australia, Adelaide, SA, Australia","institution_ids":["https://openalex.org/I170239107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100413473","display_name":"Xiaomei Li","orcid":"https://orcid.org/0000-0002-8870-3186"},"institutions":[{"id":"https://openalex.org/I170239107","display_name":"University of South Australia","ror":"https://ror.org/01p93h210","country_code":"AU","type":"education","lineage":["https://openalex.org/I170239107"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Xiaomei Li","raw_affiliation_strings":["School of Information Technology and Mathematical Sciences, University of South Australia, Adelaide, SA, Australia"],"affiliations":[{"raw_affiliation_string":"School of Information Technology and Mathematical Sciences, University of South Australia, Adelaide, SA, Australia","institution_ids":["https://openalex.org/I170239107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085471517","display_name":"Truyen Tran","orcid":"https://orcid.org/0000-0001-6531-8907"},"institutions":[{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Truyen Tran","raw_affiliation_strings":["Applied Artificial Intelligence Institute, Deakin University, Burwood, VIC, Australia"],"affiliations":[{"raw_affiliation_string":"Applied Artificial Intelligence Institute, Deakin University, Burwood, VIC, Australia","institution_ids":["https://openalex.org/I149704539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045540854","display_name":"Svetha Venkatesh","orcid":"https://orcid.org/0000-0001-8675-6631"},"institutions":[{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Svetha Venkatesh","raw_affiliation_strings":["Applied Artificial Intelligence Institute, Deakin University, Burwood, VIC, Australia"],"affiliations":[{"raw_affiliation_string":"Applied Artificial Intelligence Institute, Deakin University, Burwood, VIC, Australia","institution_ids":["https://openalex.org/I149704539"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035846381","display_name":"Thuc Duy Le","orcid":"https://orcid.org/0000-0002-9732-4313"},"institutions":[{"id":"https://openalex.org/I170239107","display_name":"University of South Australia","ror":"https://ror.org/01p93h210","country_code":"AU","type":"education","lineage":["https://openalex.org/I170239107"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Thuc Duy Le","raw_affiliation_strings":["School of Information Technology and Mathematical Sciences, University of South Australia, Adelaide, SA, Australia"],"affiliations":[{"raw_affiliation_string":"School of Information Technology and Mathematical Sciences, University of South Australia, Adelaide, SA, Australia","institution_ids":["https://openalex.org/I170239107"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5100705489"],"corresponding_institution_ids":["https://openalex.org/I149704539"],"apc_list":null,"apc_paid":null,"fwci":0.5631,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.63552972,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"18","issue":"6","first_page":"2841","last_page":"2847"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9782000184059143,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6791159510612488},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.6598289012908936},{"id":"https://openalex.org/keywords/classifier","display_name":"Classifier (UML)","score":0.5812028050422668},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.5389145016670227},{"id":"https://openalex.org/keywords/python","display_name":"Python (programming language)","score":0.5337364077568054},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.4899672567844391},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4593712091445923},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.43967968225479126},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.43773430585861206},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4026256203651428},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.38449811935424805},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.17028477787971497},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.12908700108528137},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.1268230676651001}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6791159510612488},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.6598289012908936},{"id":"https://openalex.org/C95623464","wikidata":"https://www.wikidata.org/wiki/Q1096149","display_name":"Classifier (UML)","level":2,"score":0.5812028050422668},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.5389145016670227},{"id":"https://openalex.org/C519991488","wikidata":"https://www.wikidata.org/wiki/Q28865","display_name":"Python (programming language)","level":2,"score":0.5337364077568054},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.4899672567844391},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4593712091445923},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.43967968225479126},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.43773430585861206},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4026256203651428},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.38449811935424805},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.17028477787971497},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12908700108528137},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.1268230676651001},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D060066","descriptor_name":"Protein Interaction Maps","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D060066","descriptor_name":"Protein Interaction Maps","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D060066","descriptor_name":"Protein Interaction Maps","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tcbb.2021.3076422","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2021.3076422","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:33909569","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33909569","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6200000047683716,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W1854214752","https://openalex.org/W1992570579","https://openalex.org/W1993362565","https://openalex.org/W2005895632","https://openalex.org/W2007997332","https://openalex.org/W2028133290","https://openalex.org/W2033911267","https://openalex.org/W2056944867","https://openalex.org/W2057151160","https://openalex.org/W2099474055","https://openalex.org/W2099970772","https://openalex.org/W2107665951","https://openalex.org/W2110237047","https://openalex.org/W2113878188","https://openalex.org/W2134345937","https://openalex.org/W2136410628","https://openalex.org/W2139522545","https://openalex.org/W2142295792","https://openalex.org/W2146512944","https://openalex.org/W2169353806","https://openalex.org/W2172358623","https://openalex.org/W2309067861","https://openalex.org/W2344167575","https://openalex.org/W2508622936","https://openalex.org/W2611825467","https://openalex.org/W2748889255","https://openalex.org/W2754346778","https://openalex.org/W2767281692","https://openalex.org/W2784142616","https://openalex.org/W2792132368","https://openalex.org/W2889646458","https://openalex.org/W2893493339","https://openalex.org/W2964234453","https://openalex.org/W4239510810","https://openalex.org/W4294216483","https://openalex.org/W6639055396","https://openalex.org/W6658668078","https://openalex.org/W6675071289","https://openalex.org/W6698498768","https://openalex.org/W6755128102"],"related_works":["https://openalex.org/W2361861616","https://openalex.org/W2263699433","https://openalex.org/W2341492732","https://openalex.org/W2377979023","https://openalex.org/W3187193180","https://openalex.org/W106542691","https://openalex.org/W2218034408","https://openalex.org/W2392921965","https://openalex.org/W1699080303","https://openalex.org/W2789551765"],"abstract_inverted_index":{"The":[0],"classification":[1,167],"of":[2,14,30,112,165],"clinical":[3],"samples":[4,60],"based":[5],"on":[6,58],"gene":[7,24,50,96,146],"expression":[8,25,97],"data":[9,26,63,98,194],"is":[10,72],"an":[11],"important":[12],"part":[13],"precision":[15],"medicine.":[16],"In":[17],"this":[18,87],"manuscript,":[19],"we":[20,75,134],"show":[21,135],"how":[22],"transforming":[23],"into":[27,99],"a":[28,69,77,100,117,131,174],"set":[29],"personalized":[31,49],"(sample-specific)":[32],"networks":[33,51],"can":[34],"allow":[35],"us":[36],"to":[37,42,48,94,121,177],"harness":[38],"existing":[39],"graph-based":[40,157,166],"methods":[41],"improve":[43],"classifier":[44],"performance.":[45],"Existing":[46],"approaches":[47],"have":[52],"the":[53,62,113,162,185],"limitation":[54,88],"that":[55,85,136],"they":[56],"depend":[57],"other":[59],"in":[61,189],"and":[64,155,184,193],"must":[65],"get":[66],"re-computed":[67],"whenever":[68],"new":[70,175],"sample":[71,110],"introduced.":[73],"Here,":[74],"propose":[76],"novel":[78],"method,":[79],"called":[80],"Personalized":[81],"Annotation-based":[82],"Networks":[83],"(PAN),":[84],"avoids":[86],"by":[89],"using":[90],"curated":[91],"annotation":[92],"databases":[93],"transform":[95],"graph.":[101],"Unlike":[102],"competing":[103],"methods,":[104],"PANs":[105],"are":[106,187,195],"calculated":[107],"for":[108,168],"each":[109],"independent":[111],"population,":[114],"making":[115,178],"it":[116],"more":[118],"efficient":[119],"way":[120],"obtain":[122],"single-sample":[123],"networks.":[124,180],"Using":[125],"three":[126],"breast":[127],"cancer":[128,142],"datasets":[129],"as":[130],"case":[132],"study,":[133],"PAN":[137,183],"classifiers":[138],"not":[139],"only":[140],"predict":[141],"relapse":[143],"better":[144],"than":[145],"features":[147],"alone,":[148],"but":[149],"also":[150],"outperform":[151],"PPI":[152],"(protein-protein":[153],"interactions)":[154],"population-level":[156],"classifiers.":[158],"This":[159],"work":[160],"demonstrates":[161],"practical":[163],"advantages":[164],"high-dimensional":[169],"genomic":[170],"data,":[171],"while":[172],"offering":[173],"approach":[176],"sample-specific":[179],"Supplementary":[181],"information:":[182],"baselines":[186],"implemented":[188],"Python.":[190],"Source":[191],"code":[192],"available":[196],"at":[197],"https://github.com/thinng/PAN.":[198]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}