{"id":"https://openalex.org/W3036981277","doi":"https://doi.org/10.1109/tcbb.2020.3002771","title":"PDGNet: Predicting Disease Genes Using a Deep Neural Network With Multi-View Features","display_name":"PDGNet: Predicting Disease Genes Using a Deep Neural Network With Multi-View Features","publication_year":2020,"publication_date":"2020-06-16","ids":{"openalex":"https://openalex.org/W3036981277","doi":"https://doi.org/10.1109/tcbb.2020.3002771","mag":"3036981277","pmid":"https://pubmed.ncbi.nlm.nih.gov/32750864"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2020.3002771","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2020.3002771","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051184139","display_name":"Kuo Yang","orcid":"https://orcid.org/0000-0003-0736-4512"},"institutions":[{"id":"https://openalex.org/I21193070","display_name":"Beijing Jiaotong University","ror":"https://ror.org/01yj56c84","country_code":"CN","type":"education","lineage":["https://openalex.org/I21193070"]},{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kuo Yang","raw_affiliation_strings":["BNRIST/Department of Automation, Tsinghua University, Beijing, China","Institute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0003-0736-4512","affiliations":[{"raw_affiliation_string":"BNRIST/Department of Automation, Tsinghua University, Beijing, China","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"Institute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China","institution_ids":["https://openalex.org/I21193070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100624069","display_name":"Yi Zheng","orcid":"https://orcid.org/0009-0005-9043-7103"},"institutions":[{"id":"https://openalex.org/I21193070","display_name":"Beijing Jiaotong University","ror":"https://ror.org/01yj56c84","country_code":"CN","type":"education","lineage":["https://openalex.org/I21193070"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Zheng","raw_affiliation_strings":["Institute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China","institution_ids":["https://openalex.org/I21193070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021877509","display_name":"Kezhi Lu","orcid":"https://orcid.org/0000-0003-4979-5097"},"institutions":[{"id":"https://openalex.org/I21193070","display_name":"Beijing Jiaotong University","ror":"https://ror.org/01yj56c84","country_code":"CN","type":"education","lineage":["https://openalex.org/I21193070"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kezhi Lu","raw_affiliation_strings":["Institute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0003-4979-5097","affiliations":[{"raw_affiliation_string":"Institute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China","institution_ids":["https://openalex.org/I21193070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101534582","display_name":"Kai Chang","orcid":"https://orcid.org/0000-0002-4677-2466"},"institutions":[{"id":"https://openalex.org/I21193070","display_name":"Beijing Jiaotong University","ror":"https://ror.org/01yj56c84","country_code":"CN","type":"education","lineage":["https://openalex.org/I21193070"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kai Chang","raw_affiliation_strings":["Institute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China","institution_ids":["https://openalex.org/I21193070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100387157","display_name":"Ning Wang","orcid":"https://orcid.org/0000-0002-5640-5336"},"institutions":[{"id":"https://openalex.org/I21193070","display_name":"Beijing Jiaotong University","ror":"https://ror.org/01yj56c84","country_code":"CN","type":"education","lineage":["https://openalex.org/I21193070"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ning Wang","raw_affiliation_strings":["Institute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China","institution_ids":["https://openalex.org/I21193070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004926341","display_name":"Zixin Shu","orcid":"https://orcid.org/0000-0001-6078-5645"},"institutions":[{"id":"https://openalex.org/I21193070","display_name":"Beijing Jiaotong University","ror":"https://ror.org/01yj56c84","country_code":"CN","type":"education","lineage":["https://openalex.org/I21193070"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zixin Shu","raw_affiliation_strings":["Institute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China","institution_ids":["https://openalex.org/I21193070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027501725","display_name":"Jian Yu","orcid":"https://orcid.org/0000-0002-9488-5182"},"institutions":[{"id":"https://openalex.org/I21193070","display_name":"Beijing Jiaotong University","ror":"https://ror.org/01yj56c84","country_code":"CN","type":"education","lineage":["https://openalex.org/I21193070"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jian Yu","raw_affiliation_strings":["Beijing Key Lab of Traffic Data Analysis and Mining, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Lab of Traffic Data Analysis and Mining, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China","institution_ids":["https://openalex.org/I21193070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073555542","display_name":"Baoyan Liu","orcid":"https://orcid.org/0000-0002-9677-5366"},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Baoyan Liu","raw_affiliation_strings":["Data Center of Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Data Center of Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing, China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062246119","display_name":"Z Gao","orcid":"https://orcid.org/0000-0002-6255-141X"},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4210127599","display_name":"Xiyuan Hospital","ror":"https://ror.org/02y0vze35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127599"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuye Gao","raw_affiliation_strings":["Xiyuan Hospital, China Academy of China Academy of Chinese Medical Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xiyuan Hospital, China Academy of China Academy of Chinese Medical Sciences, Beijing, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4210127599"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052838340","display_name":"Xuezhong Zhou","orcid":"https://orcid.org/0000-0002-4713-3594"},"institutions":[{"id":"https://openalex.org/I21193070","display_name":"Beijing Jiaotong University","ror":"https://ror.org/01yj56c84","country_code":"CN","type":"education","lineage":["https://openalex.org/I21193070"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuezhong Zhou","raw_affiliation_strings":["Institute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Intelligence, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China","institution_ids":["https://openalex.org/I21193070"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.7087,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.8461287,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"19","issue":"1","first_page":"575","last_page":"584"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.6751874089241028},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5512163639068604},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5363088846206665},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4963567852973938},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.4610639214515686},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4420580267906189},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4414491355419159},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.41404181718826294},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4132944643497467},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.41010645031929016},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.27997976541519165},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.25289469957351685},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.10632312297821045}],"concepts":[{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.6751874089241028},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5512163639068604},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5363088846206665},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4963567852973938},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.4610639214515686},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4420580267906189},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4414491355419159},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.41404181718826294},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4132944643497467},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.41010645031929016},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.27997976541519165},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.25289469957351685},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10632312297821045},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005246","descriptor_name":"Feedback","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005246","descriptor_name":"Feedback","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005246","descriptor_name":"Feedback","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tcbb.2020.3002771","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2020.3002771","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:32750864","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32750864","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1634564638","display_name":null,"funder_award_id":"2017YFC1703506","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G4797440519","display_name":null,"funder_award_id":"2018JBZ006","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G6821227287","display_name":null,"funder_award_id":"2019ZX09201005-002-006","funder_id":"https://openalex.org/F4320329860","funder_display_name":"National Science and Technology Major Project"},{"id":"https://openalex.org/G8996403396","display_name":null,"funder_award_id":"2017YFC1703502","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320329860","display_name":"National Science and Technology Major Project","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":78,"referenced_works":["https://openalex.org/W1577352482","https://openalex.org/W1644641054","https://openalex.org/W1677182931","https://openalex.org/W1932469787","https://openalex.org/W1970456555","https://openalex.org/W1985849948","https://openalex.org/W2010611103","https://openalex.org/W2019787708","https://openalex.org/W2038122249","https://openalex.org/W2043764521","https://openalex.org/W2048533654","https://openalex.org/W2053039860","https://openalex.org/W2056782561","https://openalex.org/W2062533676","https://openalex.org/W2074395112","https://openalex.org/W2080240378","https://openalex.org/W2089350319","https://openalex.org/W2091110954","https://openalex.org/W2097498614","https://openalex.org/W2097532544","https://openalex.org/W2099471712","https://openalex.org/W2100251770","https://openalex.org/W2100495367","https://openalex.org/W2104107436","https://openalex.org/W2104261859","https://openalex.org/W2116341502","https://openalex.org/W2116868464","https://openalex.org/W2117540545","https://openalex.org/W2118607021","https://openalex.org/W2126249571","https://openalex.org/W2136848157","https://openalex.org/W2143969840","https://openalex.org/W2144086069","https://openalex.org/W2147768505","https://openalex.org/W2148145769","https://openalex.org/W2153280946","https://openalex.org/W2153578526","https://openalex.org/W2154579312","https://openalex.org/W2154866190","https://openalex.org/W2163605009","https://openalex.org/W2187413858","https://openalex.org/W2274610632","https://openalex.org/W2405275595","https://openalex.org/W2409852956","https://openalex.org/W2537623931","https://openalex.org/W2557385283","https://openalex.org/W2558586574","https://openalex.org/W2604665028","https://openalex.org/W2618530766","https://openalex.org/W2742947407","https://openalex.org/W2768768463","https://openalex.org/W2768793602","https://openalex.org/W2775321412","https://openalex.org/W2786016794","https://openalex.org/W2788043421","https://openalex.org/W2792771702","https://openalex.org/W2799259690","https://openalex.org/W2884001105","https://openalex.org/W2890210261","https://openalex.org/W2898593560","https://openalex.org/W2911429108","https://openalex.org/W2912672202","https://openalex.org/W2913340985","https://openalex.org/W2916288174","https://openalex.org/W2918081425","https://openalex.org/W2918454358","https://openalex.org/W2921983621","https://openalex.org/W2930902918","https://openalex.org/W2942942195","https://openalex.org/W2962876161","https://openalex.org/W2963678509","https://openalex.org/W2963869731","https://openalex.org/W2964465226","https://openalex.org/W4211044101","https://openalex.org/W4300871962","https://openalex.org/W6736591718","https://openalex.org/W6758750616","https://openalex.org/W7053107269"],"related_works":["https://openalex.org/W4375867731","https://openalex.org/W2611989081","https://openalex.org/W2731899572","https://openalex.org/W4230611425","https://openalex.org/W4294635752","https://openalex.org/W4304166257","https://openalex.org/W4383066092","https://openalex.org/W3215138031","https://openalex.org/W2804383999","https://openalex.org/W4380075502"],"abstract_inverted_index":{"The":[0,113,140,201],"knowledge":[1],"of":[2,10,35,67,83,92,99,109,168,194,207],"phenotype-genotype":[3],"associations":[4],"is":[5],"crucial":[6],"for":[7,143],"the":[8,31,64,80,89,97,105,128,144,149,164,183,192,198,205],"understanding":[9],"disease":[11,26,47,73,170],"mechanisms.":[12],"Numerous":[13],"studies":[14],"have":[15,152,186],"focused":[16],"on":[17,116,172],"developing":[18,38],"efficient":[19,40],"and":[20,33,69,85,87,103,111,132,137,156,176,204],"accurate":[21],"computing":[22],"approaches":[23],"to":[24,30,45,71,95,190],"predict":[25],"genes.":[27,112,161],"However,":[28],"owing":[29],"sparseness":[32],"complexity":[34],"medical":[36,178],"data,":[37],"an":[39],"deep":[41,58,100,106],"neural":[42,59,101],"network":[43,60,102],"model":[44,61,78],"identify":[46,72],"genes":[48,74,86,146,151,167,185,196],"remains":[49],"a":[50,56,117,187],"huge":[51,188],"challenge.":[52],"Therefore,":[53],"we":[54],"develop":[55],"novel":[57],"that":[62,122,148,182],"fuses":[63],"multi-view":[65,81],"features":[66,82,108],"phenotypes":[68],"genotypes":[70],"(termed":[75],"PDGNet).":[76],"Our":[77],"integrated":[79],"diseases":[84,110],"leveraged":[88],"feedback":[90],"information":[91],"training":[93],"samples":[94],"optimize":[96],"parameters":[98],"obtain":[104],"vector":[107],"evaluation":[114],"experiments":[115],"large":[118],"data":[119,175,206],"set":[120],"indicated":[121,147,181],"PDGNet":[123,208],"obtained":[124],"higher":[125],"performance":[126],"than":[127],"state-of-the-art":[129],"method":[130],"(precision":[131],"recall":[133],"improved":[134],"by":[135],"9.55":[136],"9.63":[138],"percent).":[139],"analysis":[141],"results":[142],"candidate":[145,184],"predicted":[150,166],"strong":[153],"functional":[154],"homogeneity":[155],"dense":[157],"interactions":[158],"with":[159],"known":[160],"We":[162],"validated":[163],"top":[165],"Parkinson's":[169],"based":[171],"external":[173],"curated":[174],"published":[177],"literatures,":[179],"which":[180],"potential":[189],"guide":[191],"selection":[193],"causal":[195],"in":[197],"'wet":[199],"experiment'.":[200],"source":[202],"codes":[203],"are":[209],"available":[210],"at":[211],"https://github.com/yangkuoone/PDGNet.":[212]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
