{"id":"https://openalex.org/W3006386970","doi":"https://doi.org/10.1109/tcbb.2020.2973148","title":"FUNMarker: Fusion Network-Based Method to Identify Prognostic and Heterogeneous Breast Cancer Biomarkers","display_name":"FUNMarker: Fusion Network-Based Method to Identify Prognostic and Heterogeneous Breast Cancer Biomarkers","publication_year":2020,"publication_date":"2020-02-11","ids":{"openalex":"https://openalex.org/W3006386970","doi":"https://doi.org/10.1109/tcbb.2020.2973148","mag":"3006386970","pmid":"https://pubmed.ncbi.nlm.nih.gov/32070993"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2020.2973148","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2020.2973148","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100687807","display_name":"Xingyi Li","orcid":"https://orcid.org/0000-0002-6004-4174"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xingyi Li","raw_affiliation_strings":["School of Computer Science and Engineering, Central South University, Changsha, Hunan, P. R. China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Central South University, Changsha, Hunan, P. R. China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046328933","display_name":"Ju Xiang","orcid":"https://orcid.org/0000-0002-3045-5706"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I165911609","display_name":"Changsha Medical University","ror":"https://ror.org/05dt7z971","country_code":"CN","type":"education","lineage":["https://openalex.org/I165911609"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ju Xiang","raw_affiliation_strings":["Neuroscience Research Center & Department of Basic Medical Sciences, Changsha Medical University, Changsha, Hunan, P. R. China","School of Computer Science and Engineering, Central South University, Changsha, Hunan, P. R. China"],"affiliations":[{"raw_affiliation_string":"Neuroscience Research Center & Department of Basic Medical Sciences, Changsha Medical University, Changsha, Hunan, P. R. China","institution_ids":["https://openalex.org/I165911609"]},{"raw_affiliation_string":"School of Computer Science and Engineering, Central South University, Changsha, Hunan, P. R. China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100438360","display_name":"Jianxin Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianxin Wang","raw_affiliation_strings":["School of Computer Science and Engineering, Central South University, Changsha, Hunan, P. R. China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Central South University, Changsha, Hunan, P. R. China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017861049","display_name":"Jinyan Li","orcid":"https://orcid.org/0000-0003-1833-7413"},"institutions":[{"id":"https://openalex.org/I114017466","display_name":"University of Technology Sydney","ror":"https://ror.org/03f0f6041","country_code":"AU","type":"education","lineage":["https://openalex.org/I114017466"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jinyan Li","raw_affiliation_strings":["Advanced Analytics Institute, Faculty of Engineering & IT, University of Technology Sydney, Ultimo, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"Advanced Analytics Institute, Faculty of Engineering & IT, University of Technology Sydney, Ultimo, NSW, Australia","institution_ids":["https://openalex.org/I114017466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091157395","display_name":"Fang\u2010Xiang Wu","orcid":"https://orcid.org/0000-0002-4593-9332"},"institutions":[{"id":"https://openalex.org/I32625721","display_name":"University of Saskatchewan","ror":"https://ror.org/010x8gc63","country_code":"CA","type":"education","lineage":["https://openalex.org/I32625721"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Fang-Xiang Wu","raw_affiliation_strings":["Division of Biomedical Engineering and Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, Canada"],"affiliations":[{"raw_affiliation_string":"Division of Biomedical Engineering and Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, Canada","institution_ids":["https://openalex.org/I32625721"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100719013","display_name":"Min Li","orcid":"https://orcid.org/0000-0002-0188-1394"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Li","raw_affiliation_strings":["School of Computer Science and Engineering, Central South University, Changsha, Hunan, P. R. China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Central South University, Changsha, Hunan, P. R. China","institution_ids":["https://openalex.org/I139660479"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5100687807"],"corresponding_institution_ids":["https://openalex.org/I139660479"],"apc_list":null,"apc_paid":null,"fwci":0.9195,"has_fulltext":false,"cited_by_count":56,"citation_normalized_percentile":{"value":0.72543194,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"18","issue":"6","first_page":"2483","last_page":"2491"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.8152291774749756},{"id":"https://openalex.org/keywords/interactome","display_name":"Interactome","score":0.7635248899459839},{"id":"https://openalex.org/keywords/discriminative-model","display_name":"Discriminative model","score":0.5843284130096436},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.4885445535182953},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4672926068305969},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.45639321208000183},{"id":"https://openalex.org/keywords/genetic-heterogeneity","display_name":"Genetic heterogeneity","score":0.45442134141921997},{"id":"https://openalex.org/keywords/heterogeneous-network","display_name":"Heterogeneous network","score":0.45399484038352966},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.4427301585674286},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.37831375002861023},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.34635841846466064},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3403288722038269},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.32509148120880127},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.2638247609138489},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.2419722080230713},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.19880229234695435},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.10573288798332214},{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.10348236560821533},{"id":"https://openalex.org/keywords/wireless-network","display_name":"Wireless network","score":0.06988650560379028}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.8152291774749756},{"id":"https://openalex.org/C9760119","wikidata":"https://www.wikidata.org/wiki/Q841382","display_name":"Interactome","level":3,"score":0.7635248899459839},{"id":"https://openalex.org/C97931131","wikidata":"https://www.wikidata.org/wiki/Q5282087","display_name":"Discriminative model","level":2,"score":0.5843284130096436},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4885445535182953},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4672926068305969},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.45639321208000183},{"id":"https://openalex.org/C64618202","wikidata":"https://www.wikidata.org/wiki/Q3733697","display_name":"Genetic heterogeneity","level":4,"score":0.45442134141921997},{"id":"https://openalex.org/C158207573","wikidata":"https://www.wikidata.org/wiki/Q5747224","display_name":"Heterogeneous network","level":4,"score":0.45399484038352966},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4427301585674286},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.37831375002861023},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.34635841846466064},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3403288722038269},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32509148120880127},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2638247609138489},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2419722080230713},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.19880229234695435},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10573288798332214},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.10348236560821533},{"id":"https://openalex.org/C108037233","wikidata":"https://www.wikidata.org/wiki/Q11375","display_name":"Wireless network","level":3,"score":0.06988650560379028},{"id":"https://openalex.org/C555944384","wikidata":"https://www.wikidata.org/wiki/Q249","display_name":"Wireless","level":2,"score":0.0},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/tcbb.2020.2973148","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2020.2973148","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:32070993","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32070993","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null},{"id":"pmh:oai:opus.lib.uts.edu.au:10453/148377","is_oa":false,"landing_page_url":"http://hdl.handle.net/10453/148377","pdf_url":null,"source":{"id":"https://openalex.org/S4306401357","display_name":"UTS ePRESS (University of Technology Sydney)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I114017466","host_organization_name":"University of Technology Sydney","host_organization_lineage":["https://openalex.org/I114017466"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7699999809265137,"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities"}],"awards":[{"id":"https://openalex.org/G1121271761","display_name":null,"funder_award_id":"Program","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1474490597","display_name":null,"funder_award_id":"111 Project","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1527238211","display_name":null,"funder_award_id":"2018WK4001","funder_id":"https://openalex.org/F4320321471","funder_display_name":"Hunan Provincial Science and Technology Department"},{"id":"https://openalex.org/G1793668383","display_name":null,"funder_award_id":"60832019","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2087396116","display_name":null,"funder_award_id":"China","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2942911309","display_name":null,"funder_award_id":"2019012","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3317480652","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G391238517","display_name":null,"funder_award_id":", and","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4020255992","display_name":null,"funder_award_id":"Project","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4043378463","display_name":null,"funder_award_id":"61832019","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4066238608","display_name":null,"funder_award_id":"B18059","funder_id":"https://openalex.org/F4320327912","funder_display_name":"Higher Education Discipline Innovation Project"},{"id":"https://openalex.org/G5131139713","display_name":null,"funder_award_id":"CX20190123","funder_id":"https://openalex.org/F4320326217","funder_display_name":"Hunan Provincial Innovation Foundation for Postgraduate"},{"id":"https://openalex.org/G5169721444","display_name":null,"funder_award_id":"201901","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5939423041","display_name":null,"funder_award_id":"Technology","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5994120800","display_name":null,"funder_award_id":"Natural","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6541504238","display_name":null,"funder_award_id":"6177255","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7631435625","display_name":null,"funder_award_id":"B18059","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8740223855","display_name":null,"funder_award_id":"61772552","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321471","display_name":"Hunan Provincial Science and Technology Department","ror":"https://ror.org/04qgr7x96"},{"id":"https://openalex.org/F4320326217","display_name":"Hunan Provincial Innovation Foundation for Postgraduate","ror":null},{"id":"https://openalex.org/F4320327912","display_name":"Higher Education Discipline Innovation Project","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W1607267312","https://openalex.org/W1892363833","https://openalex.org/W1964302896","https://openalex.org/W1965302838","https://openalex.org/W1976173969","https://openalex.org/W1994803330","https://openalex.org/W2004280628","https://openalex.org/W2009019945","https://openalex.org/W2010707723","https://openalex.org/W2020541351","https://openalex.org/W2038122249","https://openalex.org/W2041993682","https://openalex.org/W2050002679","https://openalex.org/W2050574264","https://openalex.org/W2056782561","https://openalex.org/W2058865073","https://openalex.org/W2062533676","https://openalex.org/W2067305633","https://openalex.org/W2067803871","https://openalex.org/W2081375228","https://openalex.org/W2084709428","https://openalex.org/W2085934079","https://openalex.org/W2095867585","https://openalex.org/W2096079397","https://openalex.org/W2098085902","https://openalex.org/W2101181377","https://openalex.org/W2102596641","https://openalex.org/W2103017472","https://openalex.org/W2108371618","https://openalex.org/W2122863289","https://openalex.org/W2122889774","https://openalex.org/W2128985829","https://openalex.org/W2134539328","https://openalex.org/W2139372524","https://openalex.org/W2140416663","https://openalex.org/W2141393790","https://openalex.org/W2148043260","https://openalex.org/W2156166905","https://openalex.org/W2157658519","https://openalex.org/W2160450758","https://openalex.org/W2163563958","https://openalex.org/W2165253681","https://openalex.org/W2166898290","https://openalex.org/W2537679995","https://openalex.org/W2548625812","https://openalex.org/W2604808360","https://openalex.org/W2615110909","https://openalex.org/W2624701078","https://openalex.org/W2740528188","https://openalex.org/W2915108429","https://openalex.org/W2915554882","https://openalex.org/W2920876032","https://openalex.org/W2965200854","https://openalex.org/W3004474617","https://openalex.org/W6981678552"],"related_works":["https://openalex.org/W4292634579","https://openalex.org/W2964314049","https://openalex.org/W2022326234","https://openalex.org/W4388694323","https://openalex.org/W3215098729","https://openalex.org/W1531941329","https://openalex.org/W4243081378","https://openalex.org/W2622356054","https://openalex.org/W2804670115","https://openalex.org/W1979330259"],"abstract_inverted_index":{"Breast":[0],"cancer":[1,27,44,62],"is":[2,28],"a":[3,15,51,135,140],"heterogeneous":[4,23,60],"disease":[5,128],"with":[6,126,166,194],"many":[7],"clinically":[8],"distinguishable":[9],"molecular":[10],"subtypes":[11],"each":[12,102],"corresponding":[13],"to":[14,29,56,104],"cluster":[16],"of":[17,20,42,68,81,83,98,109,151,159,161],"patients.":[18],"Identification":[19],"prognostic":[21,58,122,196],"and":[22,59,71,124,153,170,182],"biomarkers":[24,33,63,175],"for":[25,38],"breast":[26,43,61,112],"detect":[30],"cluster-specific":[31],"gene":[32,99],"which":[34],"can":[35],"be":[36],"used":[37],"accurate":[39],"survival":[40],"prediction":[41],"outcomes.":[45,197],"In":[46],"this":[47],"study,":[48],"we":[49],"proposed":[50],"FUsion":[52],"Network-based":[53],"method":[54],"(FUNMarker)":[55],"identify":[57],"by":[64,177],"considering":[65],"the":[66,79,90,95,107,157,171,188],"heterogeneity":[67,82],"patient":[69],"samples":[70,85],"biological":[72,120,180],"information":[73],"from":[74,117,148],"multiple":[75],"sources.":[76],"To":[77],"reduce":[78,156],"affect":[80],"patients,":[84],"were":[86,115,132,179],"first":[87],"clustered":[88],"using":[89],"K-means":[91],"algorithm":[92],"based":[93],"on":[94,111,139],"principal":[96],"components":[97],"expression.":[100],"For":[101],"cluster,":[103],"comprehensively":[105],"evaluate":[106],"influence":[108],"genes":[110,114],"cancer,":[113],"weighted":[116],"three":[118,167],"aspects:":[119],"function,":[121],"ability":[123],"correlation":[125],"known":[127],"genes.":[129],"Then":[130],"they":[131],"ranked":[133],"via":[134],"label":[136],"propagation":[137],"model":[138],"fusion":[141],"network":[142],"that":[143,174],"combined":[144],"physical":[145],"protein":[146],"interactions":[147],"seven":[149],"types":[150],"networks":[152],"thus":[154],"could":[155],"impact":[158],"incompleteness":[160],"interactome.":[162],"We":[163],"compared":[164],"FUNMarker":[165,178],"state-of-the-art":[168],"methods":[169,190],"results":[172],"showed":[173],"identified":[176],"interpretable":[181],"had":[183],"stronger":[184],"discriminative":[185],"power":[186],"than":[187],"existing":[189],"in":[191],"differentiating":[192],"patients":[193],"different":[195]},"counts_by_year":[{"year":2026,"cited_by_count":30},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3}],"updated_date":"2026-04-15T08:11:43.952461","created_date":"2025-10-10T00:00:00"}