{"id":"https://openalex.org/W2840627412","doi":"https://doi.org/10.1109/tcbb.2020.2965919","title":"Using Weighted Extreme Learning Machine Combined With Scale-Invariant Feature Transform to Predict Protein-Protein Interactions From Protein Evolutionary Information","display_name":"Using Weighted Extreme Learning Machine Combined With Scale-Invariant Feature Transform to Predict Protein-Protein Interactions From Protein Evolutionary Information","publication_year":2020,"publication_date":"2020-01-10","ids":{"openalex":"https://openalex.org/W2840627412","doi":"https://doi.org/10.1109/tcbb.2020.2965919","mag":"2840627412","pmid":"https://pubmed.ncbi.nlm.nih.gov/31940546"},"language":"en","primary_location":{"id":"doi:10.1109/tcbb.2020.2965919","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2020.2965919","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100393871","display_name":"Jianqiang Li","orcid":"https://orcid.org/0000-0002-2208-962X"},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianqiang Li","raw_affiliation_strings":["College of Computer and Software Engineering, Shenzhen University, Shenzhen, China"],"raw_orcid":"https://orcid.org/0000-0002-2208-962X","affiliations":[{"raw_affiliation_string":"College of Computer and Software Engineering, Shenzhen University, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101585698","display_name":"Xiaofeng Shi","orcid":"https://orcid.org/0000-0002-6119-1088"},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaofeng Shi","raw_affiliation_strings":["College of Computer and Software Engineering, Shenzhen University, Shenzhen, China"],"raw_orcid":"https://orcid.org/0000-0002-6119-1088","affiliations":[{"raw_affiliation_string":"College of Computer and Software Engineering, Shenzhen University, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019805735","display_name":"Zhu\u2010Hong You","orcid":"https://orcid.org/0000-0003-1266-2696"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106108","display_name":"Xinjiang Technical Institute of Physics & Chemistry","ror":"https://ror.org/00x44h034","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106108"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhu-Hong You","raw_affiliation_strings":["Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, China"],"raw_orcid":"https://orcid.org/0000-0003-1266-2696","affiliations":[{"raw_affiliation_string":"Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, China","institution_ids":["https://openalex.org/I4210106108","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102010573","display_name":"Hai-Cheng Yi","orcid":"https://orcid.org/0000-0001-8339-396X"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106108","display_name":"Xinjiang Technical Institute of Physics & Chemistry","ror":"https://ror.org/00x44h034","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106108"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hai-Cheng Yi","raw_affiliation_strings":["Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, China"],"raw_orcid":"https://orcid.org/0000-0001-8339-396X","affiliations":[{"raw_affiliation_string":"Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, China","institution_ids":["https://openalex.org/I4210106108","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008344915","display_name":"Zhuangzhuang Chen","orcid":"https://orcid.org/0000-0002-0336-1181"},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuangzhuang Chen","raw_affiliation_strings":["College of Computer and Software Engineering, Shenzhen University, Shenzhen, China"],"raw_orcid":"https://orcid.org/0000-0002-0336-1181","affiliations":[{"raw_affiliation_string":"College of Computer and Software Engineering, Shenzhen University, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066935890","display_name":"Qiuzhen Lin","orcid":"https://orcid.org/0000-0003-2415-0401"},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiuzhen Lin","raw_affiliation_strings":["College of Computer and Software Engineering, Shenzhen University, Shenzhen, China"],"raw_orcid":"https://orcid.org/0000-0003-2415-0401","affiliations":[{"raw_affiliation_string":"College of Computer and Software Engineering, Shenzhen University, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101922755","display_name":"Min Fang","orcid":"https://orcid.org/0000-0001-6428-0345"},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Fang","raw_affiliation_strings":["College of Computer and Software Engineering, Shenzhen University, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Computer and Software Engineering, Shenzhen University, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.4771,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.91128061,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"17","issue":"5","first_page":"1546","last_page":"1554"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12676","display_name":"Machine Learning and ELM","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12676","display_name":"Machine Learning and ELM","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9455999732017517,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.554684579372406},{"id":"https://openalex.org/keywords/invariant","display_name":"Invariant (physics)","score":0.5228143930435181},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4751165509223938},{"id":"https://openalex.org/keywords/scale","display_name":"Scale (ratio)","score":0.45634186267852783},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.434726357460022},{"id":"https://openalex.org/keywords/scale-invariance","display_name":"Scale invariance","score":0.4343760013580322},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3733091950416565},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.25150781869888306},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.11102056503295898},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.10232082009315491}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.554684579372406},{"id":"https://openalex.org/C190470478","wikidata":"https://www.wikidata.org/wiki/Q2370229","display_name":"Invariant (physics)","level":2,"score":0.5228143930435181},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4751165509223938},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.45634186267852783},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.434726357460022},{"id":"https://openalex.org/C135593079","wikidata":"https://www.wikidata.org/wiki/Q1750766","display_name":"Scale invariance","level":2,"score":0.4343760013580322},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3733091950416565},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.25150781869888306},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.11102056503295898},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.10232082009315491},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C37914503","wikidata":"https://www.wikidata.org/wiki/Q156495","display_name":"Mathematical physics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016480","descriptor_name":"Helicobacter pylori","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016480","descriptor_name":"Helicobacter pylori","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016480","descriptor_name":"Helicobacter pylori","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060066","descriptor_name":"Protein Interaction Maps","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D060066","descriptor_name":"Protein Interaction Maps","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D060066","descriptor_name":"Protein Interaction Maps","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tcbb.2020.2965919","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tcbb.2020.2965919","pdf_url":null,"source":{"id":"https://openalex.org/S36029991","display_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","issn_l":"1545-5963","issn":["1545-5963","1557-9964","2374-0043"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM Transactions on Computational Biology and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31940546","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31940546","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/ACM transactions on computational biology and bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G5693537545","display_name":"\u590d\u6742\u73af\u5883\u4e0b\u7a7a\u4e2d/\u5730\u9762\u591a\u5f02\u6784\u673a\u5668\u4eba\u7acb\u4f53\u534f\u540c\u7b56\u7565\u7814\u7a76","funder_award_id":"61572330","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6733505969","display_name":null,"funder_award_id":"U1713212","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7570340352","display_name":null,"funder_award_id":"61602319","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":69,"referenced_works":["https://openalex.org/W76924599","https://openalex.org/W1530641120","https://openalex.org/W1787012077","https://openalex.org/W1884509322","https://openalex.org/W1886978693","https://openalex.org/W1985919127","https://openalex.org/W2001012564","https://openalex.org/W2001168095","https://openalex.org/W2007618103","https://openalex.org/W2021635472","https://openalex.org/W2026029065","https://openalex.org/W2032408510","https://openalex.org/W2037036397","https://openalex.org/W2037442572","https://openalex.org/W2038681300","https://openalex.org/W2048917743","https://openalex.org/W2052034930","https://openalex.org/W2057000344","https://openalex.org/W2075337064","https://openalex.org/W2077745337","https://openalex.org/W2078622091","https://openalex.org/W2079035862","https://openalex.org/W2084619201","https://openalex.org/W2090123586","https://openalex.org/W2091411809","https://openalex.org/W2094397139","https://openalex.org/W2095691234","https://openalex.org/W2095867585","https://openalex.org/W2111072639","https://openalex.org/W2124158580","https://openalex.org/W2124386111","https://openalex.org/W2127616922","https://openalex.org/W2130687290","https://openalex.org/W2134603844","https://openalex.org/W2137009853","https://openalex.org/W2138234357","https://openalex.org/W2145955247","https://openalex.org/W2145957695","https://openalex.org/W2147339185","https://openalex.org/W2147580225","https://openalex.org/W2150248355","https://openalex.org/W2150452800","https://openalex.org/W2151103935","https://openalex.org/W2152653671","https://openalex.org/W2152705149","https://openalex.org/W2153635508","https://openalex.org/W2155004936","https://openalex.org/W2161710599","https://openalex.org/W2162392441","https://openalex.org/W2167869241","https://openalex.org/W2170682402","https://openalex.org/W2191134648","https://openalex.org/W2208578958","https://openalex.org/W2295745415","https://openalex.org/W2405065882","https://openalex.org/W2513786151","https://openalex.org/W2559588458","https://openalex.org/W2612377862","https://openalex.org/W2621850397","https://openalex.org/W2734575741","https://openalex.org/W2746460995","https://openalex.org/W2793344725","https://openalex.org/W2923922207","https://openalex.org/W2994158303","https://openalex.org/W4232946552","https://openalex.org/W4233751197","https://openalex.org/W6678135826","https://openalex.org/W6678649364","https://openalex.org/W6679935922"],"related_works":["https://openalex.org/W2907003000","https://openalex.org/W2904588995","https://openalex.org/W2961085424","https://openalex.org/W2039913312","https://openalex.org/W1651110247","https://openalex.org/W4224009465","https://openalex.org/W2097033632","https://openalex.org/W2021670453","https://openalex.org/W2021783512","https://openalex.org/W2334047832"],"abstract_inverted_index":{"Protein-Protein":[0],"Interactions":[1],"(PPIs)":[2],"play":[3],"an":[4],"irreplaceable":[5],"role":[6],"in":[7,49,72,196],"biological":[8],"activities":[9],"of":[10,24,95,113,149,157,203],"organisms.":[11],"Although":[12],"many":[13],"high-throughput":[14],"methods":[15,42,195],"are":[16,43,65,116,125,164],"used":[17,80,126],"to":[18,45,56,81,91,107,127,177,213],"identify":[19],"PPIs":[20,58,109,147],"from":[21],"different":[22,197],"kinds":[23],"organisms,":[25],"they":[26],"have":[27],"some":[28],"shortcomings,":[29],"such":[30,217],"as":[31,166,168,218],"high":[32,167],"cost":[33],"and":[34,110,123,130,152,171,192,222],"time-consuming.":[35],"To":[36],"solve":[37],"the":[38,93,135,141,154,179,200,214],"above":[39],"problems,":[40],"computational":[41],"developed":[44],"predict":[46,57,108],"PPIs.":[47],"Thus,":[48],"this":[50],"paper,":[51],"we":[52,133,183],"present":[53],"a":[54,111],"method":[55,137,143,159,205],"using":[59,160],"protein":[60,63],"sequences.":[61],"First,":[62],"sequences":[64],"transformed":[66],"into":[67],"Position":[68],"Weight":[69],"Matrix":[70],"(PWM),":[71],"which":[73,209],"Scale-Invariant":[74],"Feature":[75],"Transform":[76],"(SIFT)":[77],"algorithm":[78],"is":[79,89,105,206,210],"extract":[82,128],"features.":[83,96],"Then":[84],"Principal":[85],"Component":[86],"Analysis":[87],"(PCA)":[88],"applied":[90],"reduce":[92],"dimension":[94],"At":[97],"last,":[98],"Weighted":[99],"Extreme":[100],"Learning":[101],"Machine":[102,189],"(WELM)":[103],"classifier":[104,191],"employed":[106],"series":[112],"evaluation":[114],"results":[115],"obtained.":[117],"In":[118,175],"our":[119,158,204],"method,":[120],"since":[121],"SIFT":[122],"WELM":[124],"features":[129],"classify":[131],"respectively,":[132],"called":[134],"proposed":[136,142,180],"SIFT-WELM.":[138],"When":[139],"applying":[140],"on":[144],"three":[145],"well-known":[146],"datasets":[148],"Yeast,":[150],"Human":[151],"Helicobacter.pylori,":[153],"average":[155],"accuracies":[156],"five-fold":[161],"cross":[162],"validation":[163],"obtained":[165],"94.83,":[169],"97.60":[170],"83.64":[172],"percent,":[173],"respectively.":[174],"order":[176],"evaluate":[178],"approach":[181],"properly,":[182],"compare":[184],"it":[185],"with":[186],"Support":[187],"Vector":[188],"(SVM)":[190],"other":[193],"recent-developed":[194],"aspects.":[198],"Moreover,":[199],"training":[201],"time":[202],"greatly":[207],"shortened,":[208],"obviously":[211],"superior":[212],"previous":[215],"methods,":[216],"SVM,":[219],"ACC,":[220],"PCVMZM":[221],"so":[223],"on.":[224]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":4},{"year":2018,"cited_by_count":1}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}